Nicole M McDonald, Damla Senturk, Aaron Scheffler, Jessica A Brian, Leslie J Carver, Tony Charman, Katarzyna Chawarska, Suzanne Curtin, Irva Hertz-Piccioto, Emily J H Jones, Ami Klin, Rebecca Landa, Daniel S Messinger, Sally Ozonoff, Wendy L Stone, Helen Tager-Flusberg, Sara Jane Webb, Gregory Young, Lonnie Zwaigenbaum, Shafali S Jeste
Importance: Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with different genetic etiologies. Prospective examination of familial-risk infants informs understanding of developmental trajectories preceding ASD diagnosis, potentially improving early detection. Objective: To compare outcomes and trajectories associated with varying familial risk for ASD across the first 3 years of life. Design, Setting, and Participants: This longitudinal, prospective cohort study used data from 11 sites in the Baby Siblings Research Consortium database...
January 1, 2020: JAMA Neurology