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https://www.readbyqxmd.com/read/29040656/barriers-to-the-success-of-an-electronic-pharmacovigilance-reporting-system-in-kenya-an-evaluation-three-years-post-implementation
#1
Oscar O Agoro, Sarah W Kibira, Jenny V Freeman, Hamish S F Fraser
Objective: Electronic pharmacovigilance reporting systems are being implemented in many developing countries in an effort to improve reporting rates. This study sought to establish the factors that acted as barriers to the success of an electronic pharmacovigilance reporting system in Kenya 3 years after its implementation. Materials and Methods: Factors that could act as barriers to using electronic reporting systems were identified in a review of literature and then used to develop a survey questionnaire that was administered to pharmacists working in government hospitals in 6 counties in Kenya...
October 12, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29040564/n-cadherin-identifies-human-endometrial-epithelial-progenitor-cells-by-in-vitro-stem-cell-assays
#2
Hong P T Nguyen, L Xiao, James A Deane, Ker-Sin Tan, Fiona L Cousins, Hirotaka Masuda, Carl N Sprung, Anna Rosamilia, Caroline E Gargett
STUDY QUESTION: Is there a specific surface marker that identifies human endometrial epithelial progenitor cells with adult stem cell activity using in vitro assays? SUMMARY ANSWER: N-cadherin isolates clonogenic, self-renewing human endometrial epithelial progenitor cells with high proliferative potential that differentiate into cytokeratin+ gland-like structures in vitro and identifies their location in some cells of gland profiles predominantly in basalis endometrium adjacent to the myometrium...
September 27, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29040397/demystifying-the-july-effect-in-plastic-surgery-a-multi-institutional-study
#3
Jordan T Blough, Sumanas W Jordan, Gildasio S De Oliveira, Michael M Vu, John Y S Kim
Background: The "July Effect" refers to a theoretical increase in complications that may occur with the influx of inexperienced interns and residents at the beginning of each academic year in July. Objectives: We endeavored to determine if a July Effect occurs in plastic surgery. Methods: Plastic surgery procedures were isolated from the National Surgical Quality Improvement Program registry. Cases involving residents were grouped as either having occurred within the first academic quarter (AQ1) or remaining year (AQ2-4)...
September 15, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29040303/continuing-professional-development-for-medical-nursing-and-midwifery-cadres-in-malawi-tanzania-and-south-africa-a-qualitative-evaluation
#4
Caryl Feldacker, Jillian Pintye, Sheena Jacob, Michael H Chung, Lyn Middleton, Jill Iliffe, H Nina Kim
BACKGROUND: As innovations in the prevention and treatment of HIV and TB advance, continuing professional development (CPD) of health care workers (HCWs) remains a high priority, particularly in sub-Saharan Africa where dual TB/HIV epidemics are compounded by severe HCW shortages. There is further need to examine CPD programs to identify challenges and effective solutions to strengthen HIV/TB-related CPD. METHODS: Qualitative evaluations in Malawi, Tanzania and South Africa (RSA) were conducted using key informant interviews (KIIs) and focus group discussions (FGDs) in each country to identify barriers and enablers of effective HIV/TB-related CPD...
2017: PloS One
https://www.readbyqxmd.com/read/29040290/complex-conjugated-certificateless-based-signcryption-with-differential-integrated-factor-for-secured-message-communication-in-mobile-network
#5
Sumithra Alagarsamy, S P Rajagopalan
Certificateless-based signcryption overcomes inherent shortcomings in traditional Public Key Infrastructure (PKI) and Key Escrow problem. It imparts efficient methods to design PKIs with public verifiability and cipher text authenticity with minimum dependency. As a classic primitive in public key cryptography, signcryption performs validity of cipher text without decryption by combining authentication, confidentiality, public verifiability and cipher text authenticity much more efficiently than the traditional approach...
2017: PloS One
https://www.readbyqxmd.com/read/29040044/step-up-be-counted-strategies-for-data-collection
#6
Kathleen H Johnson, Erin D Maughan, Martha Dewey Bergren, Linda C Wolfe, Jessica Gerdes
Step Up & Be Counted! (Step Up!) is an innovative project to collect nationally standardized data from the daily documentation of school nurses throughout the United States. Step Up! provides the standardization needed to promote an "apples to apples" analysis of school health resources, interventions, and outcomes across the United States. While some states have collected data for decades and have an effective infrastructure in place, other states are new to data collection and are creating processes to support data collection...
November 2017: NASN School Nurse
https://www.readbyqxmd.com/read/29040013/connectome-based-models-predict-separable-components-of-attention-in-novel-individuals
#7
Monica D Rosenberg, Wei-Ting Hsu, Dustin Scheinost, R T Constable, Marvin M Chun
Although we typically talk about attention as a single process, it comprises multiple independent components. But what are these components, and how are they represented in the functional organization of the brain? To investigate whether long-studied components of attention are reflected in the brain's intrinsic functional organization, here we apply connectome-based predictive modeling (CPM) to predict the components of Posner and Petersen's [Posner, M. I., & Petersen, S. E. The attention system of the human brain...
October 17, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/29036895/low-cost-lab-on-chip-for-the-colorimetric-detection-of-nitrate-in-mineral-water-products
#8
Mohammad F Khanfar, Wisam Al-Faqheri, Ala'aldeen Al-Halhouli
The diagnostics of health status and the quality of drinking water are among the most important United Nations sustainable development goals. However, in certain areas, wars and instability have left millions of people setting in refugee camps and dangerous regions where infrastructures are lacking and rapid diagnostics of water quality and medical status are critical. In this work, microfluidic testing chips and photometric setups are developed in cheap and portable way to detect nitrate concentrations in water...
October 14, 2017: Sensors
https://www.readbyqxmd.com/read/29036655/mfib-a-repository-of-protein-complexes-with-mutual-folding-induced-by-binding
#9
Erzsébet Fichó, István Reményi, István Simon, Bálint Mészáros
Motivation: It is commonplace that intrinsically disordered proteins (IDPs) are involved in crucial interactions in the living cell. However, the study of protein complexes formed exclusively by IDPs is hindered by the lack of data and such analyses remain sporadic. Systematic studies benefited other types of protein-protein interactions paving a way from basic science to therapeutics; yet these efforts require reliable datasets that are currently lacking for synergistically folding complexes of IDPs...
August 3, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036400/prediction-and-modeling-of-pre-analytical-sampling-errors-as-a-strategy-to-improve-plasma-nmr-metabolomics-data
#10
Carl Brunius, Anders Pedersen, Daniel Malmodin, B Göran Karlsson, Lars I Andersson, Gunnel Tybring, Rikard Landberg
Motivation: Biobanks are important infrastructures for life science research. Optimal sample handling regarding e.g. collection and processing of biological samples is highly complex, with many variables that could alter sample integrity and even more complex when considering multiple study centers or using legacy samples with limited documentation on sample management. Novel means to understand and take into account such variability would enable high-quality research on archived samples...
July 14, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036359/profia-a-data-preprocessing-workflow-for-flow-injection-analysis-coupled-to-high-resolution-mass-spectrometry
#11
Alexis Delabrière, Ulli M Hohenester, Benoit Colsch, Christophe Junot, François Fenaille, Etienne A Thévenot
Motivation: Flow Injection Analysis coupled to High-Resolution Mass Spectrometry (FIA-HRMS) is a promising approach for high-throughput metabolomics. FIA-HRMS data, however, cannot be preprocessed with current software tools which rely on liquid chromatography separation, or handle low resolution data only. Results: We thus developed the proFIA package, which implements a suite of innovative algorithms to preprocess FIA-HRMS raw files, and generates the table of peak intensities...
July 14, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29035767/life-cycle-energy-impacts-for-adapting-an-urban-water-supply-system-to-droughts
#12
Ka Leung Lam, Jennifer R Stokes-Draut, Arpad Horvath, Joe L Lane, Steven J Kenway, Paul A Lant
In recent years, cities in some water stressed regions have explored alternative water sources such as seawater desalination and potable water recycling in spite of concerns over increasing energy consumption. In this study, we evaluate the current and future life-cycle energy impacts of four alternative water supply strategies introduced during a decade-long drought in South East Queensland (SEQ), Australia. These strategies were: seawater desalination, indirect potable water recycling, network integration, and rainwater tanks...
October 9, 2017: Water Research
https://www.readbyqxmd.com/read/29035630/a-population-health-measurement-framework-evidence-based-metrics-for-assessing-community-level-population-health-in-the-global-budget-context
#13
Elham Hatef, Elyse C Lasser, Hadi H K Kharrazi, Chad Perman, Russ Montgomery, Jonathan P Weiner
Population health is one of the pillars of the Triple Aim to improve US health care. The authors developed a framework for population health measurement and a proposed set of measures for further exploration to guide the population health efforts in Maryland. The authors searched peer-reviewed, expert-authored literature and current public health measures. Using a semi-structured analysis, a framework was proposed, which consisted of a conceptual model of several domains and identified population health measures addressing them...
October 16, 2017: Population Health Management
https://www.readbyqxmd.com/read/29035454/the-relationship-between-mdm2-t309g-polymorphism-and-leukemia-in-the-chinese-population-evidence-from-a-meta-analysis
#14
Dewan Zhao, Ting Liu
BACKGROUND: Increasing numbers of studies have been carried out on the association of MDM2 T309G polymorphism with susceptibility to leukemia and have generated conflicting results. This meta-analysis updated and revaluated the possible associations between MDM2 T309G polymorphism and leukemia in the Chinese population. METHODS: The PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure, and Chinese Biology Medicine were searched up to February 2017...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29035442/long-noncoding-rna-pvt1-as-a-potent-predictor-of-prognosis-in-cancers-a-meta-analysis
#15
Xuefeng Pan, Baohui Li, Naijun Fan, Juntang Li, Fengbo Cai, Guang Zhao, Guobao Zheng, Chunfang Gao
BACKGROUND: Plasmacytoma variant translocation 1 (PVT1), an oncogenic long noncoding RNA located in a recognized cancer-risk gene region-8q24, is significantly overexpressed in various cancers. Many studies have found that high expression of PVT1 was correlated with poor prognosis. METHODS: This meta-analysis was performed by searching electronic databases Pubmed, Web of Science, Chinese National Knowledge Infrastructure, WanFang, and ChongQing VIP for eligible papers on the prognostic impact and clinicopathological characteristics of PVT1 expression in cancer from inception to January 31, 2017...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29035338/integrating-medication-therapy-management-mtm-services-provided-by-community-pharmacists-into-a-community-based-accountable-care-organization-aco
#16
Brian Isetts
(1) Background: As the U.S. healthcare system evolves from fee-for-service financing to global population-based payments designed to be accountable for both quality and total cost of care, the effective and safe use of medications is gaining increased importance. The purpose of this project was to determine the feasibility of integrating medication therapy management (MTM) services provided by community pharmacists into the clinical care teams and the health information technology (HIT) infrastructure for Minnesota Medicaid recipients of a 12-county community-based accountable care organization (ACO)...
October 16, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29034171/does-exposure-to-new-transport-infrastructure-result-in-modal-shifts-patterns-of-change-in-commute-mode-choices-in-a-four-year-quasi-experimental-cohort-study
#17
Eva Heinen, Amelia Harshfield, Jenna Panter, Roger Mackett, David Ogilvie
BACKGROUND: Intervention studies suggest that changing the built environment may encourage a modal shift from car travel towards active travel. However, little is known about the detail of patterns of changes in travel behaviour. METHOD: Adult commuters working in Cambridge (UK) completed annual questionnaires between 2009 and 2012. Commuting was assessed using a validated seven-day travel-to-work record. The intervention consisted of the opening of a guided busway with a path for walking and cycling in 2011...
September 2017: Journal of Transport & Health
https://www.readbyqxmd.com/read/29034161/going-green-ex-post-valuation-of-a-multipurpose-water-infrastructure-in-northern-italy
#18
Arnaud Reynaud, Denis Lanzanova, Camino Liquete, Bruna Grizzetti
A contingent valuation approach is used to estimate how households value different multipurpose infrastructures (conventional or green) for managing flood risk and water pollution. As a case study we consider the Gorla Maggiore water park located in the Lombardy Region, in Northern Italy. The park is a neo-ecosystem including an infrastructure to treat waste water and store excess rain water, built in 2011 on the shore of the Olona River in an area previously used for poplar plantation. This park is the first one of this type built in Italy...
October 2017: Ecosystem Services
https://www.readbyqxmd.com/read/29032792/centralisation-of-oesophagectomy-in-australia-is-only-caseload-critical
#19
Richard Hummel, Ngoc Hoang Ha, Andrew Lord, Markus I Trochsler, Guy Maddern, Harsh Kanhere
Objective High caseload is considered one of the most important factors for good outcomes after high-risk surgeries such as oesophagectomy. However, many Australian centres perform low volumes of oesophagectomies due to demographics. The aim of the present study was to audit outcome after oesophagectomy in an Australian low-volume centre over a period of 13 years and to discuss potential contributors to outcome other than just case volume.Methods Perioperative and long-term outcomes of all oesophagectomies over a 13-year period in a low-volume Australian tertiary care centre were analysed retrospectively...
October 16, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/29032618/scaling-up-interventions-to-improve-infant-and-young-child-feeding-in-india-what-will-it-take
#20
Rasmi Avula, Vanessa M Oddo, Suneetha Kadiyala, Purnima Menon
We assessed India's readiness to deliver infant and young child feeding (IYCF) interventions by examining elements related to policy, implementation, financing, and evidence. We based our analysis on review of (a) nutrition policy guidance and program platforms, (b) published literature on interventions to improve IYCF in India, and (c) IYCF program models implemented between 2007 and 2012. We find that Indian policies are well aligned with global technical guidance on counselling interventions. However, guidelines for complementary food supplements (CFS) need to be reexamined...
October 2017: Maternal & Child Nutrition
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