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https://www.readbyqxmd.com/read/29244732/middleware-for-plug-and-play-integration-of-heterogeneous-sensor-resources-into-the-sensor-web
#1
Enoc Martínez, Daniel M Toma, Simon Jirka, Joaquín Del Río
The study of global phenomena requires the combination of a considerable amount of data coming from different sources, acquired by different observation platforms and managed by institutions working in different scientific fields. Merging this data to provide extensive and complete data sets to monitor the long-term, global changes of our oceans is a major challenge. The data acquisition and data archival procedures usually vary significantly depending on the acquisition platform. This lack of standardization ultimately leads to information silos, preventing the data to be effectively shared across different scientific communities...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244633/leveraging-the-global-health-service-partnership-model-for-workforce-development-in-global-radiation-oncology
#2
Omoruyi Credit Irabor, Vanessa Bradford Kerry, Juliet Matton, Wilfred Ngwa
A major contributor to the disparity in cancer outcome across the globe is the limited health care access in low- and middle-income countries that results from the shortfall in human resources for health (HRH), fomented by the limited training and leadership capacity of low-resource countries. In 2012, Seed Global Health teamed up with the Peace Corps to create the Global Health Service Partnership, an initiative that has introduced a novel model for tackling the HRH crises in developing regions of the world...
December 15, 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29243742/corrigendum-a-comprehensive-infrastructure-for-big-data-in-cancer-research-accelerating-cancer-research-and-precision-medicine
#3
Izumi V Hinkson, Tanja M Davidsen, Juli D Klemm, Ishwar Chandramouliswaran, Anthony R Kerlavage, Warren A Kibbe
[This corrects the article on p. 83 in vol. 5, PMID: 28983483.].
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/29243574/stock-outs-improvisations-and-processes-of-infrastructuring-in-uganda-s-hiv-aids-and-malaria-programmes
#4
René Umlauf, Sung-Joon Park
This paper examines the stock-outs of medicines and diagnostic devices in Uganda. Our aim is to trace and compare interruptions in the supply of antiretrovirals and Rapid Diagnostic Tests in order to provide an ethnographic account of the complex role that improvisations play within global health infrastructures. We will argue that the fragmented and mobile infrastructures of these key global health technologies require and necessitate improvisations by the different actors involved as well as on almost all levels of the Ugandan health-care system...
December 15, 2017: Global Public Health
https://www.readbyqxmd.com/read/29243483/relative-binding-free-energy-calculations-in-drug-discovery-recent-advances-and-practical-considerations
#5
Zoe Cournia, Bryce Allen, Woody Sherman
Accurate in silico prediction of protein-ligand binding affinities has been a primary objective of structure-based drug design for decades due to the putative value it would bring to the drug discovery process. However, computational methods have historically failed to deliver value in real-world drug discovery applications due to a variety of scientific, technical, and practical challenges. Recently, a family of approaches commonly referred to as relative binding free energy (RBFE) calculations, which rely on physics-based molecular simulations and statistical mechanics, have shown promise in reliably generating accurate predictions in the context of drug discovery projects...
December 15, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29242749/setting-the-research-and-implementation-agenda-for-equitable-access-to-surgical-care-in-south-africa
#6
REVIEW
Sarah Rayne, Sule Burger, Stephanie Van Straten, Bruce Biccard, Mathume Joseph Phaahla, Martin Smith
South Africa is an upper-middle-income country with widespread social and geographical inequality of surgical provision. The National Forum on Surgery and Anaesthesia in South Africa brought together various stakeholders, including government, societies, academic clinicians and the biomedical industry, to define the core strategy for a national surgical plan. During the forum, presentations and breakaway workshops explored and reported the challenges and opportunities these stakeholders may have in sustaining and improving surgical provision in South Africa...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29242711/effect-of-point-of-care-diagnostics-on-maternal-outcomes-in-human-immunodeficiency-virus-infected-women-systematic-review-and-meta-analysis
#7
Tivani P Mashamba-Thompson, Rebecca L Morgan, Benn Sartorius, Brittany Dennis, Paul K Drain, Lehana Thabane
Introduction: The World Health Organization advocates for increased accessibility of HIV-related point-of-care (POC) diagnostics in settings that lack laboratory infrastructure. The aim of this study is to assess the impact of POC diagnostics on maternal health outcomes in HIV-infected women. Methods: A systematic literature review used multiple data sources as follows: Cochrane Infectious Disease Group Specialized Register; Cochrane Central Register of Control Trials, published in The Cochrane Library; PubMed; EBSCOhost and LILACS from January 2000 to October 2015...
June 2017: Point of Care
https://www.readbyqxmd.com/read/29242103/the-neural-network-for-face-recognition-insights-from-an-fmri-study-on-developmental-prosopagnosia
#8
Yuanfang Zhao, Zonglei Zhen, Xiqin Liu, Yiying Song, Jia Liu
Face recognition is supported by collaborative work of multiple face-responsive regions in the brain. Based on findings from individuals with normal face recognition ability, a neural model has been proposed with the occipital face area (OFA), fusiform face area (FFA), and face-selective posterior superior temporal sulcus (pSTS) as the core face network (CFN) and the rest of the face-responsive regions as the extended face network (EFN). However, little is known about how these regions work collaboratively for face recognition in our daily life...
December 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/29241376/non-endoscopic-biopsy-techniques-a-review
#9
David O Otuya, Yogesh Verma, Hamid Farrokhi, Lisa Higgins, Mireille Rosenberg, Christopher Damman, Guillermo J Tearney
Diseases of the stomach and small intestine account for approximately 20% of all gastrointestinal (GI)-related mortality. Biopsy of the stomach and small intestine remains a key diagnostic tool for most of the major diseases that affect the GI tract. While endoscopic means for obtaining biopsy is generally the standard of care, it has several limitations that make it less ideal for pediatric patients and in low resource areas of the world. Therefore, non-endoscopic means for obtaining biopsy samples is of interest in these settings...
December 15, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29240684/optimal-multi-type-sensor-placement-for-structural-identification-by-static-load-testing
#10
Numa Joy Bertola, Maria Papadopoulou, Didier Vernay, Ian F C Smith
Assessing ageing infrastructure is a critical challenge for civil engineers due to the difficulty in the estimation and integration of uncertainties in structural models. Field measurements are increasingly used to improve knowledge of the real behavior of a structure; this activity is called structural identification. Error-domain model falsification (EDMF) is an easy-to-use model-based structural-identification methodology which robustly accommodates systematic uncertainties originating from sources such as boundary conditions, numerical modelling and model fidelity, as well as aleatory uncertainties from sources such as measurement error and material parameter-value estimations...
December 14, 2017: Sensors
https://www.readbyqxmd.com/read/29240569/paediatric-procedural-sedation-and-analgesia-by-emergency-physicians-in-a-country-with-a-recent-establishment-of-emergency-medicine
#11
Maybritt I Kuypers, Gaël J P Smits, Eva P Baerends, Erick Oskam, Eef P J Reijners, Lisette A A Mignot-Evers, Wendy A M H Thijssen, Frans B Plötz, Erik H M Korsten
OBJECTIVES: Paediatric patients receive less procedural sedation and analgesia (PSA) in the emergency department compared with adults, especially in countries where emergency medicine is at an early stage of development. The objectives of this study were to evaluate the adverse events and efficacy of paediatric PSA in a country with a recent establishment of emergency medicine and to describe which factors aided implementation. METHODS: This is a prospective, multicentre, observational study of paediatric patients undergoing PSA by the first trained emergency physicians (EPs) in The Netherlands...
December 13, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/29240466/developing-an-infrastructure-to-support-clinical-academic-careers
#12
Karen Strickland
Research and evidence-based practice underpins the delivery of high-quality patient care. Developing the research capacity and capability of nurses, midwives and allied health professionals requires a robust emphasis and the necessary support infrastructure to encourage and develop practitioners to follow a clinical academic career pathway. Clinical academic partnerships between higher education and healthcare institutions can offer a blend of required expertise with mutual benefits. This article reports on a recent Florence Nightingale Foundation and Council of Deans of Health Leadership Scholarship improvement project to establish an infrastructure to support the development of clinical academic roles to enhance the provision of evidence-based patient care in the North East of Scotland...
December 14, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29239943/achieving-milestones-as-a-prerequisite-for-proceeding-with-a-clinical-trial
#13
Angela M Mickle, Hannah R Maybrier, Anke C Winter, Sherry L McKinnon, Brian A Torres, Nan Lin, Eric J Lenze, Susan Stark, Maxwell R Muench, Eric Jacobsohn, Sharon K Inouye, Michael S Avidan, Troy S Wildes
BACKGROUND: Although the National Institutes of Health (NIH) invests $30 billion in research annually, many funded studies fail to generate results that can inform practice. The National Institutes of Health introduced a phased funding mechanism as one potential solution. Study-specific milestones are established for an initial pilot phase. We assess the utility of this phased approach through the ongoing Electroencephalography (EEG) Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES) pragmatic clinical trial...
December 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29238608/study-protocol-for-enhancing-parenting-in-cancer-epic-development-and-evaluation-of-a-brief-psycho-educational-intervention-to-support-parents-with-cancer-who-have-young-children
#14
Lesley Stafford, Michelle Sinclair, Jane Turner, Louise Newman, Claire Wakefield, Mei Krishnasamy, G Bruce Mann, Leslie Gilham, Kylie Mason, Paula Rauch, Julia Cannell, Penelope Schofield
Background: Parents with cancer have high rates of psychological morbidity, and their children are at risk of poor psychosocial outcomes, particularly in the context of parental distress and poor family communication. Parents express concerns about the impact of cancer on their children and report a lack of professional guidance in meeting their children's needs. Few parenting interventions exist and current interventions have extensive infrastructure demands making them unsuitable for routine use in most health settings...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29238499/exploring-perceptions-of-policymakers-about-main-strategies-to-enhance-fertility-rate-a-qualitative-study-in-iran
#15
Ali Akbar Haghdoost, Roya Safari-Faramani, Mohammad Reza Baneshi, Reza Dehnavieh, Mahlegha Dehghan
Background: Total fertility rate in Iran has declined unprecedentedly over the past thirty years. However, debating on proper strategies to increase fertility is still a matter of discussion among experts. Objective: To explain the main strategies to increase fertility from the viewpoints of the policy makers. Methods: This is a qualitative study using content analysis. Purposeful sampling approach was used to gather data. The data were collected via semi-structured interviews...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238451/a-survey-of-telepractice-in-speech-language-pathology-and-audiology-in-india
#16
Haritha S Mohan, Ayesha Anjum, Prema K S Rao
Telepractice has emerged as a form of service delivery to assess and treat individuals with communication disorders. The present study surveyed speech-language pathologists and audiologists in India about the use of telepractice. Two hundred and five (N=205) speech-language pathologists and audiologists responded to a questionnaire, with 12.19% reporting their use of telepractice to deliver clinical services. Respondents also indicated an urgent shortage of professionals in India to deliver clinical services in speech-language pathology and audiology, and opined that these needs can be met via the use of telepractice...
2017: International Journal of Telerehabilitation
https://www.readbyqxmd.com/read/29238410/saved-by-design-the-case-of-legal-protection-by-design
#17
Mireille Hildebrandt
This discussion note does three things: (1) it explains the notion of 'legal protection by design' in relation to data-driven infrastructures that form the backbone of our new 'onlife world', (2) it explains how the notion of 'by design' relates to the relational nature of what an environment affords its inhabitants, referring to the work of James Gibson, and (3) it explains how this affects our understanding of human capabilities in relation to the affordances of changing environments. Finally, this brief note argues that 'safer by design' in the case of nanotechnology will require legal protection by design to make sure that human capabilities are reinvented and sustained in nano-technical environments...
2017: Nanoethics
https://www.readbyqxmd.com/read/29237960/spritzer-for-diagnostic-cytopathology
#18
Rashmi Metgud, Smitha Naik, Shrikant Patel
BACKGROUND: Exfoliative cytology is an easy, economical, noninvasive, and feasible method for early detection and screening program of any premalignant or malignant lesion. In case of routine cytological procedure, classical Papanicolaou (PAP) stain is widely used while Romanowsky stains are sparingly used. Leishman-Giemsa (LG) cocktail, being a easier, cost effective staining technique, has not been used in exfoliative cytology. Therefore, this pilot study was carried out to compare and contrast the role of LG stain in routine cytological procedure which is very cost-effective, less time-consuming and requires less infrastructural support...
October 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/29236014/identification-of-potential-sewer-mining-locations-a-monte-carlo-based-approach
#19
I K Tsoukalas, C K Makropoulos, S N Michas
Rapid urbanization affecting demand patterns, coupled with potential water shortages due to supply side impacts of climatic changes, has led to the emergence of new technologies for water and wastewater reuse. Sewer mining (SM) is a novel decentralized option that could potentially provide non-potable water for urban uses, including for example the irrigation of urban green spaces, providing a mid-scale solution to effective wastewater reuse. SM is based on extracting wastewater from local sewers and treatment at the point of demand and entails in some cases the return of treatment residuals back to the sewer system...
December 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29235181/fuzheng-huayu-capsule-as-an-adjuvant-treatment-for-hbv-related-cirrhosis-a-systematic-review-and-meta-analysis
#20
REVIEW
Tao Wang, Xuelin Zhou, Honghong Liu, Jiabo Wang, Ping Zhang, Yun Zhu, Kun Li, Shizhang Wei, Haotian Li, Lifu Wang, Ruilin Wang, Yanling Zhao
Fuzheng Huayu (FZHY) capsule, a formulated traditional Chinese medicine product with 6 Chinese herbs, is widely used for HBV-related cirrhosis as an adjuvant treatment. However, the efficacy of FZHY capsule for HBV-induced cirrhosis did not be comprehensively proved by systematic analysis. Our current analysis was aimed to assess the efficacy and safety of FZHY capsule by an evidence-based method. Databases, including China National Knowledge Infrastructure, Wangfang, VIP medicine information system, Pubmed, Embase, and Cochrane Library, were searched, and the randomized controlled trials of FZHY capsule were used for the treatment of HBV-associated liver cirrhosis...
December 13, 2017: Phytotherapy Research: PTR
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