Arnaud Bourdin, Jérémy Charriot, Clément Boissin, Engi Ahmed, Carey Suehs, Arthur De Sevin, Mathilde Volpato, Laurie Pahus, Delphine Gras, Isabelle Vachier, Laurence Halimi, Dominic Hamerlijnck, Pascal Chanez
PURPOSE: Asthma exacerbations are inflammatory events that rarely result in full hospitalization following an ER visit. Unfortunately, certain patients require prolonged support, including occasional external lung support through ECMO or ECCOR (with subsequent further exposure to other life-threatening issues), and some die. In parallel, biologics are revolutionizing severe asthma management, mostly in T2 high patients. METHODS: We extensively reviewed the current unmet needs surrounding ICU-admitted asthma exacerbations, with a focus on currently available drugs and the underlying biological processes involved...
August 2021: Allergy