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https://www.readbyqxmd.com/read/27912929/survival-failure-modes-and-function-of-combined-distal-femur-and-proximal-tibia-reconstruction-following-tumor-resection
#1
F Sevelda, W Waldstein, J Panotopoulos, C Stihsen, A Kaider, P T Funovics, R Windhager
BACKGROUND: Tumor spread to the knee joint or skip metastasis to the adjacent bones of the knee require reconstruction with combined distal femur and proximal tibia replacements. The literature on implant survival and failure modes with this type of reconstruction is sparse. The goals of this study were to determine the implant survival, the different failure modes and the functional outcome of this megaendoprosthetic reconstruction. PATIENTS AND METHODS: Thirty-nine patients with combined distal femur and proximal tibia reconstruction were retrospectively reviewed...
November 23, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27910822/prolonged-in-vitro-precultivation-alleviates-post-implantation-inflammation-and-promotes-stable-subcutaneous-cartilage-formation-in-a-goat-model
#2
Yi Liu, Dan Li, Zongqi Yin, Xusong Luo, Wei Liu, Wenjie Zhang, Zhiyong Zhang, Yilin Cao, Yu Liu, Guangdong Zhou
Synthetic biodegradable scaffolds such as polylactic acid coated polyglycolic acid (PLA-PGA) are especially suitable for engineering shaped cartilage such as auricle, but they induce a serious inflammatory reaction particularly in the immunologically aggressive subcutaneous site, leading to resorption of the engineered autologous cartilage. Our previous study in a rabbit model has demonstrated 2 weeks of in vitro precultivation could significantly alleviate the post-implantation inflammation induced by PLA-PGA engineered cartilaginous grafts, but reproduction of this result failed in a preclinical goat model...
December 2, 2016: Biomedical Materials
https://www.readbyqxmd.com/read/27910136/mitral-valve-surgery-following-failed-mitraclip-implantation
#3
Piotr Mazur, Salvior Mok, Amar Krishnaswamy, Samir Kapadia, Jose L Navia
Mitral valve disruption is a rare but serious complication of MitraClip insertion. This review provides an update on surgical interventions following MitraClip failure, and discusses possible valve injuries and surgical approaches.
December 1, 2016: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/27909532/ajmaline-challenge-to-unmask-infrahisian-disease-in-patients-with-recurrent-and-unexplained-syncope-preserved-ejection-fraction-with-or-without-conduction-abnormalities-on-surface-ecg
#4
Francesco Pentimalli, Luca Bacino, Matteo Ghione, Giambattista Siri, Massimo Gazzarata, Paolo Bellotti
Background: Pharmacological challenge with class I antiarrhythmic drug is a recommended diagnostic test in patients with unexplained syncope only in the presence of bundle branch block, when non-invasive tests have failed to make the diagnosis. Its role in patients with minor or no conduction disturbances on 12-leads ECG has not been evaluated yet. It is also not clear which are the values of His-Ventricular interval to be considered diagnostic. We sought to evaluate the role of ajmaline challenge in unmasking the presence of an infrahisian disease in patients with recurrent and unexplained syncope, regardless of the existence of conduction disturbances on surface ECG...
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27909501/-two-for-the-price-of-one-a-single-lead-implantable-cardioverter-defibrillator-system-with-a-floating-atrial-dipole
#5
REVIEW
Nicole E Worden Md, Musab Alqasrawi Md, Siva M Krothapalli Md, Alexander Mazur Md
In patients known to be a high risk for sudden cardiac arrest, implantable cardioverter defibrillators (ICD) are a proven therapy to reduce risk of death. However, in patients without conventional indications for pacing, the optimal strategy for type of device, dual- versus single-chamber, remains debatable. The benefit of prophylactic pacing in this category of patients has never been documented. Although available atrial electrograms in a dual chamber system improve interpretation of stored arrhythmia events, allow monitoring of atrial fibrillation and may potentially reduce the risk of inappropriate shocks by enhancing automated arrhythmia discrimination, the use of dual-chamber ICDs has a number of disadvantages...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27908653/molecular-changes-in-children-with-heart-failure-undergoing-left-ventricular-assist-device-therapy
#6
Elizabeth Medina, Carmen C Sucharov, Penny Nelson, Shelley D Miyamoto, Brian L Stauffer
OBJECTIVE: To determine whether left ventricular assist device (LVAD) treatment in children with heart failure would result in the modification of molecular pathways involved in heart failure pathophysiology. STUDY DESIGN: Forty-seven explanted hearts from children were studied (16 nonfailing control, 20 failing, and 11 failing post-LVAD implantation [F-LVAD]). Protein expression and phosphorylation states were determined by receptor binding assays and Western blots...
November 29, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27906080/tonic-and-burst-spinal-cord-stimulation-waveforms-for-the-treatment-of-chronic-intractable-pain-study-protocol-for-a-randomized-controlled-trial
#7
Konstantin V Slavin, Richard B North, Timothy R Deer, Peter Staats, Kristina Davis, Roni Diaz
BACKGROUND: Burst stimulation is a novel form of neurostimulation for the treatment of chronic pain which has demonstrated promise in small uncontrolled studies, but has not yet gained approval for use in the U.S. We report the study methods for an ongoing multicenter, randomized, controlled, cross-over study designed to gain United States Food and Drug Administration (FDA) approval for burst stimulation. METHODS: Participants who are candidates for a currently approved neurostimulation device were enrolled and screened...
December 1, 2016: Trials
https://www.readbyqxmd.com/read/27902498/immediate-replacement-of-single-teeth-with-immediately-loaded-implants-retrospective-analysis-of-a-clinical-case-series
#8
Ashok Sethi, Thomas Kaus
INTRODUCTION: The purpose of this retrospective analysis of clinical data was to evaluate the predictability of replacing failing single teeth with immediately placed implants loaded via a transitional (provisional) restoration. MATERIALS AND METHODS: Implants were placed immediately at the time of extraction of failing single teeth that met predetermined inclusion criteria. A detailed protocol was followed to enable immediate loading of the implant with the use of prefabricated abutments in combination with transitional restorations...
November 29, 2016: Implant Dentistry
https://www.readbyqxmd.com/read/27895348/a-6-year-evaluation-of-223-tapered-dental-implants-and-associated-prosthesis-in-92-patients-at-a-university-hospital
#9
Sana Ehsen Nagi, Farhan Raza Khan, Rabia Ali
The aim of the retrospective study was to assess the clinical and radiographic outcome of the dental implant surgery and prosthetics. It was conducted at the Aga Khan University Hospital, Karachi, and comprised of medical charts and radiographic records of patients visiting between 2010 and 2015. Variables such as implant dimensions, final prosthesis, method of retention, loading protocol and patient factors were analysed. A total of 223 implants (143(64.1%) in maxilla and 80(35.9%) in mandible) were placed in 92 subjects (50(54...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27895345/a-review-of-the-failed-cases-of-dental-implants-at-a-university-hospital-in-karachi-pakistan
#10
Farhan Raza Khan, Rabia Ali, Sana Ehsan Nagi
The retrospective study was conducted to assess the dental implants that experienced failure. It was conducted at the dental clinic of the Aga Khan University Hospital, Karachi, and comprised record of dental implants from July 2010 to June 2015. Variables such as patient age, gender and systemic status, length and diameter of implants, bone grafting, type of definitive prosthesis (crown or bridge or overdenture), nature of retention (cement versus screw retained), loading strategy (immediate versus delayed loading), etc...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27894264/optical-coherence-tomography-findings-after-longitudinal-ablation-for-an-underexpanded-stent-in-a-heavily-calcified-lesion-a-case-report
#11
Masahiro Koide, Keiji Inoue, Akiko Matsuo, Hiroshi Fujita
BACKGROUND: Heavy coronary artery calcification is responsible for stent underexpansion, which is associated with increased in-stent restenosis. Here we report a case in which optical coherence tomography (OCT) demonstrated that the metal component of an underexpanded stent previously implanted in a heavy calcified lesion had been completely removed after ablation with rotational atherectomy. CASE PRESENTATION: An 83-year-old man with exertional angina was referred to our hospital...
November 29, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27893924/deciding-how-best-to-treat-cartilage-defects
#12
Lucy Oliver-Welsh, Justin W Griffin, Maximilian A Meyer, Matthew E Gitelis, Brian J Cole
The decision-making regarding and treatment of cartilage abnormalities requires a systematic approach. This article reviews the concepts and principles that guide the management of this complex problem. The precise incidence, demographics, and progression of cartilage lesions have not been clearly delineated. Pursuing a patient-centered approach that considers the available nonsurgical and surgical options remains the cornerstone of patient care. The importance of determining concomitant knee pathologies, the proper interpretation and implications of imaging findings, and an accurate determination of the intra-articular and subchondral findings represent the primary elements of the decision analysis...
January 0: Orthopedics
https://www.readbyqxmd.com/read/27893490/total-wrist-arthrodesis-indications-and-clinical-outcomes
#13
David H Wei, Paul Feldon
Total wrist arthrodesis remains an important technique in the surgical armamentarium of upper extremity surgeons. The procedure has evolved over time but continues to provide reliable pain relief at the expense of wrist motion. It is indicated for management of a wide variety of upper extremity conditions, including rheumatoid arthritis, posttraumatic osteoarthritis, cerebral palsy, and brachial plexus injuries, and as a salvage technique after failed implant arthroplasty. Recent studies demonstrate high levels of patient satisfaction and good functional outcomes after bilateral wrist fusion...
November 22, 2016: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/27890199/-what-is-the-role-of-primary-or-secondary-hemiarthroplasty-for-distal-radius-fractures-in-independent-elderly-patients
#14
G Herzberg, M Burnier
The authors report their experience with wrist hemiarthroplasty for acute irreparable distal radius fractures in independent elderly patients (12 women, mean age 76years) and following failed initial treatment in the same population (5 women, mean age 75years). The first 11 cases have a mean follow-up of 30months. No complications requiring implant removal were reported. At follow-up, the mean VAS for pain was 1/10, the mean flexion-extension arc was 60°, the Lyon Wrist score was 73 % and the PRWE (Patient-Related Wrist Evaluation) was 22 points...
December 2016: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/27886358/outcomes-of-total-hip-replacement-in-limbs-affected-by-poliomyelitis
#15
Cesare Faldini, Marcello De Fine, Alberto Di Martino, Daniele Fabbri, Raffaele Borghi, Mohammadreza Chehrassan, Francesco Traina
INTRODUCTION: The outcomes of total hip replacement in patients suffering from residual poliomyelitis are poorly covered in the literature. In this retrospective study we posed the question of whether total hip replacement performed for degenerative hip diseases in limbs with residual poliomyelitis could determine satisfactory mid-term clinical and radiographic results, with a reasonable complication rate. METHODS: A retrospective study was carried out to assess the results of 14 total hip replacements performed on 14 patients with residual poliomyelitis on the involved limb from June 1999 to September 2011...
November 15, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27885966/er-cr-ysgg-laser-effectively-ablates-single-species-biofilms-on-titanium-disks-without-detectable-surface-damage
#16
Jason M Strever, Jaebum Lee, William Ealick, Mark Peacock, Daniel Shelby, Cristiano Susin, Donald Mettenberg, Ahmed El-Awady, Frederick Rueggeberg, Christopher W Cutler
BACKGROUND: Increasing evidence implicates biofilms, consisting of species such as Porphyromonas gingivalis, in the etiology of peri-implantitis. Multiple approaches to ablate biofilms on failing implants have been proposed, include the use of lasers; most recently the Er,Cr:YSGG laser. The purpose of this study is to establish an in-vitro single-species biofilm model on implant surfaces and determine power settings of the Er,Cr:YSGG laser that remove the biofilm while not causing physical damage to the disk...
November 25, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27885230/the-implantation-of-a-loop-recorder-to-detect-the-cause-of-pre-syncope-in-an-85-year-old-man
#17
Yasuhisa Iriki, Naoya Oketani, Mitsuru Ohishi
The patient was an-85-year-old man with hypertension and hyperlipidemia. The patient had a history of faintness on standing. He visited our hospital after experiencing chest oppression and pre-syncope in 2015. Brain magnetic resonance imaging and echocardiography did not detect any structural brain or heart disease. Ischemic heart disease was suspected based on the myocardial scintigraphy findings, but coronary angiography revealed no unusual findings. Holter electrocardiography did not reveal the reason for his symptoms...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27882429/endovascular-management-of-recurrent-spontaneous-hemarthrosis-after-arthroplasty
#18
Marcin K Kolber, Pratik A Shukla, Abhishek Kumar, Adam Zybulewski, Todd Markowitz, James E Silberzweig
PURPOSE: Recurrent spontaneous hemarthrosis is an infrequent but debilitating late complication of joint replacement, affecting up to 1.6% of patients with arthroplasty of the affected joint. Repeated episodes of bleeding result in an inflammatory cascade that further propagates bleeding events. Open and arthroscopic synovectomy are often performed when conservative treatments fail. Transarterial embolization is increasingly utilized as a less invasive option; however, its role is not widely established...
November 23, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27881957/the-effects-of-excitatory-and-inhibitory-social-cues-on-cocaine-seeking-behavior
#19
Mark A Smith, Huailin Zhang, Andrea M Robinson
Social partners influence the likelihood of using drugs, developing a substance use disorder and relapse to drug use after a period of abstinence. Preclinical studies report that social cues influence the acquisition of cocaine use, the escalation of cocaine use over time, and the compulsive patterns of cocaine use that emerge during an extended binge. The purpose of this study was to examine the effects of social cues on the reinstatement of cocaine-seeking behavior after a period of abstinence. Male rats were obtained at weaning, assigned to triads (three rats/cage), reared to adulthood and implanted with intravenous catheters...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27879505/the-effect-of-transpedicular-screw-design-on-its-performance-in-vertebral-bone-under-tensile-loads-a-parametric-study
#20
Ron N Alkaly, Dan L Bader
STUDY DESIGN: A biomechanical study using bovine thoracolumbar spines. OBJECTIVE: To study investigated whether thread design parameters aimed at altering the state of stress at the screw-bone interface increase the screw's holding power. SUMMARY AND BACKGROUND DATA: Internal spinal fixators utilizing transpedicular screw fixation are used to achieve early stabilization of the injured spine in a range of clinical conditions. Despite advances in the design of internal spinal fixation systems, implant loosening, and catastrophic failures at the screw-bone interface remains a serious complication in adult spine surgery...
December 2016: Clinical Spine Surgery
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