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https://www.readbyqxmd.com/read/29779269/-the-applications-of-periodontal-gingival-surgery-%C3%A2-alternative-materials
#1
Er-Jia Mao
The main purposes of periodontal graft surgery include achieving root coverage, improving the clinical attachment level and keratinized tissue, and advancing the procedure of periodontal plastic surgery. Autogenous graft, such as subepithelial connective tissue graft-based procedure, provide the best outcomes for mean and complete root coverage, as well as increase in keratinized tissue. However, a disadvantage of the procedure is in the location of the operation itself: the additional surgical site (palate)...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29775151/selection-of-endoscopic-or-transcranial-surgery-for-tuberculum-sellae-meningiomas-according-to-specific-anatomical-features-a-retrospective-multicenter-analysis-kosen-002
#2
Doo-Sik Kong, Chang-Ki Hong, Sang Duk Hong, Do-Hyun Nam, Jung-Il Lee, Ho Jun Seol, Jiwoong Oh, Dong Gyu Kim, Yong Hwy Kim
OBJECTIVE The endoscopic endonasal approach (EEA) and the transcranial approach (TCA) are good options for the treatment of tuberculum sellae (TS) meningiomas. The objective of this study was to identify the key anatomical features in TS meningiomas and compare the two surgical approaches. METHODS The authors retrospectively reviewed clinical data in 178 patients with TS meningiomas treated at 3 institutions between January 2010 and July 2016. Patients with tumors encasing the internal carotid artery or anterior cerebral artery or involving the anterior clinoid process or cavernous sinus were excluded...
May 18, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29767762/surgical-outcomes-following-repeat-transsphenoidal-surgery-for-nonfunctional-pituitary-adenomas-a-retrospective-comparative-study
#3
Joshua Bakhsheshian, Sarah Wheeler, Ben A Strickland, Martin H Pham, Robert C Rennert, John Carmichael, Martin Weiss, Gabriel Zada
BACKGROUND: Endonasal transsphenoidal surgery (ETSS) remains the preferred treatment for recurrent or residual nonfunctional pituitary adenomas (NFPAs). However, surgical complications and outcomes with repeat ETSS are unclear. OBJECTIVE: To compare outcomes from primary and repeat ETSS in patients with NFPAs. METHODS: Retrospective review of ETSS for NFPAs at USC University Hospital and LAC + USC Medical Center between 2000 and 2015. Patients with ≥3-mo follow-up data were included...
May 15, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29766937/enhanced-resection-of-primary-high-grade-gliomas-using-a-combination-of-intraoperative-magnetic-resonance-imaging-and-intraoperative-fluorescence-5-aminolevulinic-acid-a-single-centre-experience
#4
Vikas Sharma, Rishabh Kedia, Karanjit S Narang, Ajaya N Jha
Background: The extent of resection (EOR) of a tumor is a proven prognostic factor in patients undergoing surgery for suspected high grade glioma. A few recent publications have shown the importance of intraoperative magnetic resonance imaging (iMRI) with 5-aminolevulinic acid (5-ALA) fluorescence-guidance in order to maximally increase the EOR. Aim: The objective of our study was to calculate the effect on survival of patients with high grade gliomas of resection using both iMRI and 5-ALA fluorescence-guidance as intraoperative adjuncts...
May 2018: Neurology India
https://www.readbyqxmd.com/read/29738687/o-antigens-of-escherichia-coli-strains-o81-and-hs3-104-are-structurally-and-genetically-related-except-o-antigen-glucosylation-in-e-coli-hs3-104
#5
E L Zdorovenko, Y Wang, A S Shashkov, T Chen, O G Ovchinnikova, B Liu, A K Golomidova, V V Babenko, A V Letarov, Y A Knirel
Glycerophosphate-containing O-specific polysaccharides (OPSs) were obtained by mild acidic degradation of lipopolysaccharides isolated from Escherichia coli type strain O81 and E. coli strain HS3-104 from horse feces. The structures of both OPSs and of the oligosaccharide derived from the strain O81 OPS by treatment with 48% HF were studied by monosaccharide analysis and one- and two-dimensional 1H- and 13C-NMR spectroscopy. Both OPSs had similar structures and differed only in the presence of a side-chain glucose residue in the strain HS3-104 OPS...
May 2018: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/29715576/prognostic-factors-and-the-management-of-anaplastic-meningioma
#6
Gui-Jun Zhang, Yun-Sheng Zhang, Guo-Bin Zhang, Da Li, Li-Wei Zhang, Zhen Wu, Jun-Ting Zhang
OBJECTIVES: Anaplastic meningiomas (AMs)tend to have a higher local recurrence rate and metastasize. but few studies have reported on the prognosis and management of patients with AM, this study aimed to increase the understanding of the prognosis, management and history of AM. PATIENTS AND METHODS: All patients (n = 56) underwent surgeries in our hospital between December 2008 and January 2016. Postoperative pathology reports confirmed the diagnosis of AM. Prognostic factors and the management were analysed in this study...
March 27, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29702217/resolving-the-systematic-positions-of-enigmatic-taxa-manipulating-the-chloroplast-genome-data-of-saxifragales
#7
Wenpan Dong, Chao Xu, Ping Wu, Tao Cheng, Jing Yu, Shiliang Zhou, De-Yuan Hong
Accurately resolving the phylogeny of enigmatic taxa is always a challenge in phylogenetic inference. Such uncertainties could be due to systematic errors or model violations. Here, we provide an example demonstrating how these factors affect the positioning of Paeoniaceae within Saxifragales based on chloroplast genome data. We newly assembled 14 chloroplast genomes from Saxifragales, and by combining these genomes with those of 63 other angiosperms, three datasets were assembled to test different hypotheses proposed by recent studies...
April 24, 2018: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/29698392/gtr-ego-independent-torc1-activation-is-achieved-through-a-glutamine-sensitive-interaction-with-pib2-on-the-vacuolar-membrane
#8
Hirofumi Ukai, Yasuhiro Araki, Shintaro Kira, Yu Oikawa, Alexander I May, Takeshi Noda
TORC1 is a central regulator of cell growth in response to amino acids. The role of the evolutionarily conserved Gtr/Rag pathway in the regulation of TORC1 is well-established. Recent genetic studies suggest that an additional regulatory pathway, depending on the activity of Pib2, plays a role in TORC1 activation independently of the Gtr/Rag pathway. However, the interplay between the Pib2 pathway and the Gtr/Rag pathway remains unclear. In this study, we show that Pib2 and Gtr/Ego form distinct complexes with TORC1 in a mutually exclusive manner, implying dedicated functional relationships between TORC1 and Pib2 or Gtr/Rag in response to specific amino acids...
April 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29691776/management-of-glioblastoma-at-safety-net-hospitals
#9
Michael G Brandel, Robert C Rennert, Christian Lopez Ramos, David R Santiago-Dieppa, Jeffrey A Steinberg, Reith R Sarkar, Arvin R Wali, J Scott Pannell, James D Murphy, Alexander A Khalessi
BACKGROUND: Safety-net hospitals (SNHs) provide disproportionate care for underserved patients. Prior studies have identified poor outcomes, increased costs, and reduced access to certain complex, elective surgeries at SNHs. However, it is unknown whether similar patterns exist for the management of glioblastoma (GBM). We sought to determine if patients treated at HBHs receive equitable care for GBM, and if safety-net burden status impacts post-treatment survival. METHODS: The National Cancer Database was queried for GBM patients diagnosed between 2010 and 2015...
April 24, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29680921/neurosurgical-treatment-of-gangliogliomas-in-children-and-adolescents-long-term-follow-up-of-a-single-institution-series-of-32-patients
#10
Tryggve Lundar, Bernt Johan Due-Tønnessen, Radek Fric, Arild Egge, Bård Krossnes, Paulina Due-Tønnessen, Einar Stensvold, Petter Brandal
OBJECT: The object of this study was to delineate long-term results of the surgical treatment of pediatric tumors classified as ganglioglioma or gangliocytoma. METHODS: A cohort of consecutive patients 19 years or younger who had undergone primary resection of CNS tumors during the years 1980-2016 at a single institution were reviewed in this retrospective study of surgical morbidity, mortality, and academic achievement and/or work participation. Gross motor function and activities of daily living were scored using the Barthel Index (BI)...
April 22, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29661677/orthodontic-periodontal-interactions-orthodontic-extrusion-in-interdisciplinary-regenerative-treatments
#11
Maria Giacinta Paolone, Roberto Kaitsas
Orthodontics is a periodontal treatment. "Guided orthodontic regeneration" (GOR) procedures use orthodontic movements in perio-restorative patients. The GOR technique includes a guided orthodontic "soft tissue" regeneration (GOTR) and a guided orthodontic "bone" regeneration (GOBR) with a plastic soft tissue approach and a regenerating reality. The increased amount of soft tissue gained with orthodontic movement can be used for subsequent periodontal regenerative techniques. The increased amount of bone can as well improve primary implant stability and, eventually, simplify a GTR technique to regenerate soft tissues, to restore tooth with external resorption in aesthetic zone or to extract a tooth to create new hard-soft tissue for adjacent teeth...
April 13, 2018: International Orthodontics
https://www.readbyqxmd.com/read/29661278/comparing-survival-outcomes-of-gross-total-resection-and-subtotal-resection-with-radiotherapy-for-craniopharyngioma-a-meta-analysis
#12
Guoqing Wang, Xiaoyang Zhang, Mengzhao Feng, Fuyou Guo
BACKGROUND: Recent studies suggest that subtotal resection (STR) followed by radiation therapy (RT) is an appealing alternative to gross total resection (GTR) for craniopharyngioma, but it remains controversial. We conducted a meta-analysis to determine whether GTR is superior to STR with RT for craniopharyngioma. MATERIALS AND METHODS: A systematic search was performed for articles published until October 2017 in the PubMed, Embase, and Cochrane Central databases...
June 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29629229/ambiguity-in-the-dural-tail-sign-on-mri
#13
Ramesh S Doddamani, Rajesh K Meena, Dattaraj Sawarkar
Background: Meningiomas give rise to the dural tail sign (DTS) on contrast-enhanced magnetic resonance imaging (CEMRI). The presence of DTS does not always qualify for a meningioma, as it is seen in only 60-72% of cases. This sign has been described in various other lesions like lymphomas, metastasis, hemangiopericytomas, schwannomas and very rarely glioblastoma multiforme (GBM). The characteristics of dural-based GBMs are discussed here, as only eleven such cases are reported in the literature till date...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29624151/histopathological-features-predictive-of-local-control-of-atypical-meningioma-after-surgery-and-adjuvant-radiotherapy
#14
William C Chen, Stephen T Magill, Ashley Wu, Harish N Vasudevan, Olivier Morin, Manish K Aghi, Philip V Theodosopoulos, Arie Perry, Michael W McDermott, Penny K Sneed, Steve E Braunstein, David R Raleigh
OBJECTIVE The goal of this study was to investigate the impact of adjuvant radiotherapy (RT) on local recurrence and overall survival in patients undergoing primary resection of atypical meningioma, and to identify predictive factors to inform patient selection for adjuvant RT. METHODS One hundred eighty-two patients who underwent primary resection of atypical meningioma at a single institution between 1993 and 2014 were retrospectively identified. Patient, meningioma, and treatment data were extracted from the medical record and compared using the Kaplan-Meier method, log-rank tests, multivariate analysis (MVA) Cox proportional hazards models with relative risk (RR), and recursive partitioning analysis...
April 6, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29618896/cortical-bone-graft-and-gtr-membrane-as-ceiling-effect-in-alveolar-bone-grafting
#15
Philip Mathew, P Varun Menon
Background: In orofacial cleft deformity cases, bone grafting is a very essential step in reconstruction of the residual alveolar cleft defect. Material and Methods: Though various authors have put forth different techniques and graft sources for alveolar bone grafting, at our center, we have used iliac crest as the graft source and cortical bone graft with GTR membrane as "ceiling effect". Results: We have evaluated a series of cases of secondary alveolar bone grafting done with this technique by same surgeon at our center and have found great success...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29617848/surgery-for-glioblastoma-in-light-of-molecular-markers-impact-of-resection-and-mgmt-promoter-methylation-in-newly-diagnosed-idh-1-wild-type-glioblastomas
#16
Florian Gessler, Joshua D Bernstock, Anne Braczynski, Stephanie Lescher, Peter Baumgarten, Patrick N Harter, Michel Mittelbronn, Tianxia Wu, Volker Seifert, Christian Senft
BACKGROUND: Previous studies addressing the influence of surgery on the outcome of patients with glioblastomas (GBM) have not addressed molecular markers. The value of surgery versus the tumor's major biological markers remains unclear. OBJECTIVE: We investigate the extent of resection as a prognosticator for patients with newly diagnosed primary GBM with the incorporation of molecular diagnostics as per the updated WHO 2016 diagnostic criteria for GBM. METHODS: Patients with newly diagnosed GBM who underwent resection were prospectively included within a database...
March 27, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29607223/single-sitting-surgical-treatment-of-generalized-aggressive-periodontitis-using-gtr-technique-and-immediate-implant-placement-with-10-year-follow-up
#17
Fatme Mouchref Hamasni, Fady El Hajj, Rima Abdallah
This case report exhibits a patient with generalized aggressive periodontitis who has been under maintenance for the past 12 years after being surgically treated in a single sitting and restored with dental implants. A 41-year-old systemically healthy male patient presented complaining of lower anterior teeth mobility and pain in the upper right quadrant. After clinical and radiographic examination, the upper right molars and lower anterior incisors were deemed unrestorable. Covered by doxycycline, the patient received a nonsurgical periodontal treatment...
2018: Case Reports in Dentistry
https://www.readbyqxmd.com/read/29606040/decision-making-algorithm-for-minimally-invasive-approaches-to-anterior-skull-base-meningiomas
#18
Malte Ottenhausen, Kavelin Rumalla, Andrew F Alalade, Prakash Nair, Emanuele La Corte, Iyan Younus, Jonathan A Forbes, Atef Ben Nsir, Matei A Banu, Apostolos John Tsiouris, Theodore H Schwartz
OBJECTIVE Anterior skull base meningiomas are benign lesions that cause neurological symptoms through mass effect on adjacent neurovascular structures. While traditional transcranial approaches have proven to be effective at removing these tumors, minimally invasive approaches that involve using an endoscope offer the possibility of reducing brain and nerve retraction, minimizing incision size, and speeding patient recovery; however, appropriate case selection and results in large series are lacking. METHODS The authors developed an algorithm for selecting a supraorbital keyhole minicraniotomy (SKM) for olfactory groove meningiomas or an expanded endoscopic endonasal approach (EEA) for tuberculum sella (TS) or planum sphenoidale (PS) meningiomas based on the presence or absence of olfaction and the anatomical extent of the tumor...
April 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29600905/therapeutic-outcomes-of-transsphenoidal-surgery-in-pediatric-patients-with-craniopharyngiomas-a-single-center-study
#19
Shozo Yamada, Noriaki Fukuhara, Mitsuo Yamaguchi-Okada, Hiroshi Nishioka, Akira Takeshita, Yasuhiro Takeuchi, Naoko Inoshita, Junko Ito
OBJECTIVE The aim of this study was to analyze the outcomes of transsphenoidal surgery (TSS) in a single-center clinical series of pediatric craniopharyngioma patients treated with gross-total resection (GTR). METHODS The authors retrospectively reviewed the surgical outcomes for 65 consecutive patients with childhood craniopharyngiomas (28 girls and 37 boys, mean age 9.6 years) treated with TSS (45 primary and 20 repeat surgeries) between 1990 and 2015. Tumors were classified as subdiaphragmatic or supradiaphragmatic...
March 30, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29596640/multiple-factors-confounding-phylogenetic-detection-of-selection-on-codon-usage
#20
Simon Laurin-Lemay, Hervé Philippe, Nicolas Rodrigue
Detecting selection on codon usage (CU) is a difficult task, since CU can be shaped by both the mutational process and selective constraints operating at the DNA, RNA and protein levels. Yang and Nielsen (2008) developed a test (which we call CUYN) for detecting selection on CU using two competing mutation-selection models of codon substitution. The null model assumes that CU is determined by the mutation bias alone, whereas the alternative model assumes that both mutation bias and/or selection act on CU. In applications on mammalian-scale alignments, the CUYN test detects selection on CU for numerous genes...
March 27, 2018: Molecular Biology and Evolution
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