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https://www.readbyqxmd.com/read/28548887/effects-of-bone-morphogenetic-protein-2-on-vertical-bone-augmentation-in-a-canine-model
#1
Yung-Ting Hsu, Khalid Al-Hezaimi, Pablo Galindo-Moreno, Francisco O'Valle, Abdulaziz Al-Rasheed, Hom-Lay Wang
BACKGROUND: Vertical bone augmentation (VBA) remains unpredictable and challenging for most clinicians. This study was aimed to compare hard tissue outcomes of VBA, with and without rhBMP-2, under space-making titanium mesh in a canine model. METHODS: Eleven male beagle dogs were used in the study. Experimental ridge defects were created to form atrophic ridges. VBA was performed via guide bone regeneration (GBR) using titanium mesh and allografts. In experimental hemimandibles, rhBMP-2/ACS was well mixed with allografts prior to procedures, whereas a control buffer was applied within controls...
May 26, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28527186/fabrication-of-nano-hydroxyapatite-chitosan-membrane-with-asymmetric-structure-and-its-applications-in-guided-bone-regeneration
#2
Ying Tu, Chen Chen, Yubao Li, Yi Hou, Min Huang, Li Zhang
The development of guided bone regeneration (GBR) technique brings a promising alternative for bone defects and fracture healing. In this study, an asymmetric nano-hydroxyapatite/chitosan (n-HA/CS) composite GBR membrane was fabricated by means of solution-blending and solvent-evaporating in vacuum. The membranes were characterized using SEM, XPS and contact angle. It was found that the composite membrane displayed an asymmetric structure, in which the upper surface was CS and the under surface was a complex of n-HA and CS, and some interactions between n-HA and CS were also confirmed to exist...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28527001/the-relative-abundance-of-dimethylsulfoniopropionate-dmsp-among-other-zwitterions-in-branching-coral-at-heron-island-southern-great-barrier-reef
#3
Hilton B Swan, Elisabeth S M Deschaseaux, Graham B Jones, Bradley D Eyre
Dimethylsulfoniopropionate (DMSP) and eleven other target zwitterions were quantified in the branch tips of six Acropora species and Stylophora pistillata hard coral growing on the reef flat surrounding Heron Island in the southern Great Barrier Reef (GBR), Australia. Hydrophilic interaction liquid chromatography mass spectrometry (HILIC-MS) was used for sample analysis with isotope dilution MS applied to quantify DMSP. The concentration of DMSP was ten times greater in A. aspera than A. valida, with this difference being maintained throughout the spring, summer and winter seasons...
May 20, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28526119/effects-of-temperature-salinity-and-composition-of-the-dinoflagellate-assemblage-on-the-growth-of-gambierdiscus-carpenteri-isolated-from-the-great-barrier-reef
#4
Leanne Sparrow, Paolo Momigliano, Garry R Russ, Kirsten Heimann
Increases in reported incidence of ciguatera fish poisoning (hereafter ciguatera) have been linked to warmer sea temperatures that are known to trigger coral bleaching events. The drivers that trigger blooms of ciguatera-causing dinoflagellates on the Great Barrier Reef (GBR) are poorly understood. This study investigated the effects of increased temperatures and lowered salinities, often associated with environmental disturbance events, on the population growth of two strains of the potentially ciguatera-causing dinoflagellate, Gambierdiscus carpenteri (NQAIF116 and NQAIF380)...
May 2017: Harmful Algae
https://www.readbyqxmd.com/read/28521935/rainfall-contributes-30-of-the-dissolved-inorganic-nitrogen-exported-from-a-southern-great-barrier-reef-river-basin
#5
Robert Packett
A study was conducted to estimate how much of the annual load of dissolved inorganic nitrogen (DIN) from Great Barrier Reef (GBR) river basins could come from rainfall. Results suggest rainfall contributed ~37% of the average annual DIN load from the Fitzroy Basin over three wet seasons. Rainfall DIN contribution at plot to sub-catchment scale ranged from 5 to >100% for study sites in the Fitzroy and Pioneer Basins. An estimate using measured and modelled data indicates ~28% of the longer-term average annual DIN load from the entire GBR catchment may originate from rainfall...
May 15, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28500409/physicochemical-and-biological-characteristics-of-bmp-2-igf-1-loaded-three-dimensional-coaxial-electrospun-fibrous-membranes-for-bone-defect-repair
#6
Lihua Yin, Shaohua Yang, Miaomiao He, Yuchen Chang, Kaijuan Wang, Yidan Zhu, Yuhui Liu, Yaoren Chang, Zhanhai Yu
Coaxial electrospun fibrous membranes show favorable mechanical properties for use in guided bone regeneration (GBR). We used coaxial electrospinning technology to fabricate three-dimensional nanofiber membranes loaded with BMP-2 and IGF-1, and assessed the physicochemical and biological properties of these novel membranes in vitro. We fabricated four experimental groups of BMP-2/IGF-1/BSA-loaded membranes with different flow ratios (shell/core). Membrane characteristics were assessed by scanning and transmission electron microscopy, and laser confocal microscopy...
June 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28485822/delayed-coral-recovery-in-a-warming-ocean
#7
Kate Osborne, Angus A Thompson, Alistair J Cheal, Michael J Emslie, Kerryn A Johns, Michelle J Jonker, Murray Logan, Ian R Miller, Hugh P A Sweatman
Climate change threatens coral reefs across the world. Intense bleaching has caused dramatic coral mortality in many tropical regions in recent decades, but less obvious chronic effects of temperature and other stressors can be equally threatening to the long-term persistence of diverse coral-dominated reef systems. Coral reefs persist if coral recovery rates equal or exceed average rates of mortality. While mortality from acute destructive events is often obvious and easy to measure, estimating recovery rates and investigating the factors that influence them requires long-term commitment...
May 9, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28482532/application-of-peg-and-egcg-modified-collagen-base-membrane-to-promote-osteoblasts-proliferation
#8
Chenyu Chu, Jia Deng, Yi Hou, Lin Xiang, Yingying Wu, Yili Qu, Yi Man
Collagen membranes possess ideal biological properties and can be served as a barrier for supporting infiltration and proliferation of osteoblasts in guided bone regeneration (GBR). However, pure collagen lacks desirable mechanical properties and also leads to inflammation, resulting in progressive bone resorption. In our previous study, EGCG cross-linked collagen membranes exhibit better mechanical properties and anti-inflammatory effect. However, higher concentration of EGCG may not improve cell viability...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28481338/eating-glutinous-brown-rice-twice-a-day-for-8-weeks-improves-glycemic-control-in-japanese-patients-with-diabetes-mellitus
#9
T Nakayama, Y Nagai, Y Uehara, Y Nakamura, S Ishii, H Kato, Y Tanaka
OBJECTIVE: We recently reported that eating glutinous brown rice (GBR) for 1 day improved the whole-day glucose profile and postprandial plasma glucose level compared with eating white rice (WR) or standard brown rice. However, it was unknown whether eating GBR could maintain improvement of glycemic control for a longer period. Therefore, we evaluated the effect of GBR intake for 8 weeks on glycemic control in outpatients with diabetes mellitus. METHODS: This was an open-label randomized crossover study in outpatients with type 2 diabetes...
May 8, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28480987/gaba-metabolism-and-its-role-in-gamma-band-oscillatory-activity-during-auditory-processing-an-mrs-and-eeg-study
#10
Christine Wyss, Desmond H Y Tse, Michael Kometer, Jürgen Dammers, Rita Achermann, N Jon Shah, Wolfram Kawohl, Irene Neuner
Gamma-aminobutyric acid (GABA) and glutamate are believed to have inhibitory and exhibitory neuromodulatory effects that regulate the brain's response to sensory perception. Furthermore, frequency-specific synchronization of neuronal excitability within the gamma band (30-80 Hz) is attributable to a homeostatic balance between excitation and inhibition. However, our understanding of the physiological mechanism underlying gamma rhythms is based on animal models. Investigations of the relationship between GABA concentrations, glutamate concentrations, and gamma band activity in humans were mostly restricted to the visual cortex and are conflicting...
May 8, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28476351/evidence-of-antibiotic-resistance-in-enterobacteriales-isolated-from-green-sea-turtles-chelonia-mydas-on-the-great-barrier-reef
#11
Md Shamim Ahasan, Jacqueline Picard, Lisa Elliott, Robert Kinobe, Leigh Owens, Ellen Ariel
This study investigated Enterobacteriales and their antimicrobial resistance in green sea turtles captured adjacent to the central Great Barrier Reef (GBR) and proximate to urban development. Cloacal swabs were taken from 73 green turtles between 2015 and 2016. A total of 154 out of 341 Gram-negative bacterial isolates were identified as Enterobacteriales that represent 16 different species from 9 different genera. The dominant isolates were Citrobacter (30.52%), Edwardsiella (21.43%) and Escherichia (12.34%)...
May 2, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28466608/guided-bone-regeneration-with-recombinant-human-bone-morphogenetic-protein-9-loaded-on-either-deproteinized-bovine-bone-mineral-or-a-collagen-barrier-membrane
#12
Nikola Saulacic, Masako Fujioka-Kobayashi, Eizaburo Kobayashi, Benoit Schaller, Richard J Miron
BACKGROUND: Recombinant human bone morphogenetic protein 9 (rhBMP9) has been considered the most osteoinductive growth factor of the BMP-family and has much translation potential for guided bone regeneration (GBR) procedures. PURPOSE: The aim of this study was to compare bone formation using rhBMP9 loaded with different carrier systems including deprotenized bovine bone mineral (BioOss, BO) or collagen barrier membranes (BioGide, BG) in a rabbit GBR model. MATERIALS AND METHODS: rhBMP9 was loaded either on BO; named BO/BMP9, or BG; named BG/BMP9 to investigate the better carrier system for rhBMP9...
May 2, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28462006/regenerative-capacity-of-augmented-bone-in-rat-calvarial-guided-bone-augmentation-model
#13
Tatsuya Kubota, Akira Hasuike, Yasumasa Ozawa, Takanobu Yamamoto, Katsuyoshi Tsunori, Yutaka Yamada, Shuichi Sato
PURPOSE: Guided bone regeneration (GBR) is the most widely used technique to regenerate and augment bones. Even though augmented bones (ABs) have been examined histologically in many studies, few studies have been conducted to examine the biological potential of these bones and the healing dynamics following their use. Moreover, whether the bone obtained from the GBR procedure possesses the same functions as the existing autogenous bone is uncertain. In particular, little attention has been paid to the regenerative ability of GBR bone...
April 2017: Journal of Periodontal & Implant Science
https://www.readbyqxmd.com/read/28441338/effects-of-3d-printed-polycaprolactone-%C3%AE-tricalcium-phosphate-membranes-on-guided-bone-regeneration
#14
Jin-Hyung Shim, Joo-Yun Won, Jung-Hyung Park, Ji-Hyeon Bae, Geunseon Ahn, Chang-Hwan Kim, Dong-Hyuk Lim, Dong-Woo Cho, Won-Soo Yun, Eun-Bin Bae, Chang-Mo Jeong, Jung-Bo Huh
This study was conducted to compare 3D-printed polycaprolactone (PCL) and polycaprolactone/β-tricalcium phosphate (PCL/β-TCP) membranes with a conventional commercial collagen membrane in terms of their abilities to facilitate guided bone regeneration (GBR). Fabricated membranes were tested for dry and wet mechanical properties. Fibroblasts and preosteoblasts were seeded into the membranes and rates and patterns of proliferation were analyzed using a kit-8 assay and by scanning electron microscopy. Osteogenic differentiation was verified by alizarin red S and alkaline phosphatase (ALP) staining...
April 25, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28435485/impact-of-health-policy-changes-on-emergency-medicine-in-maryland-stratified-by-socioeconomic-status
#15
Laura Pimentel, David Anderson, Bruce Golden, Edward Wasil, Fermin Barrueto, Jon M Hirshon
INTRODUCTION: On January 1, 2014, the financing and delivery of healthcare in the state of Maryland (MD) profoundly changed. The insurance provisions of the Patient Protection and Affordable Care Act (ACA) began implementation and a major revision of MD's Medicare waiver ushered in a Global Budget Revenue (GBR) structure for hospital reimbursement. Our objective was to analyze the impact of these policy changes on emergency department (ED) utilization, hospitalization practices, insurance profiles, and professional revenue...
April 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28429906/eating-glutinous-brown-rice-for-one-day-improves-glycemic-control-in-japanese-patients-with-type-2-diabetes-assessed-by-continuous-glucose-monitoring
#16
Yuko Terashima, Yoshio Nagai, Hiroyuki Kato, Akio Ohta, Yasushi Tanaka
BACKGROUND AND OBJECTIVES: We investigated whether intake of non-glutinous brown rice (BR) or glutinous brown rice (GBR) for 1 day had an influence on the daily glucose profile measured by continuous glucose monitoring (CGM) when compared with intake of non-glutinous white rice (WR). METHODS AND STUDY DESIGN: A total of 37 inpatients with type 2 diabetes mellitus (T2DM) were recruited for a 3-day randomized triple cross-over trial in which they ate WR, BR, or GBR for 1 day each...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28401197/platelet-rich-fibrin-prf-in-implants-dentistry-in-combination-with-new-bone-regenerative-flapless-technique-evolution-of-the-technique-and-final-results
#17
Antonio Cortese, Giuseppe Pantaleo, Massimo Amato, Candace M Howard, Lorenzo Pedicini, Pier Paolo Claudio
Most common techniques for alveolar bone augmentation are guided bone regeneration (GBR) and autologous bone grafting. GBR studies demonstrated long-term reabsorption using heterologous bone graft. A general consensus has been achieved in implant surgery for a minimal amount of 2 mm of healthy bone around the implant. A current height loss of about 3-4 mm will result in proper deeper implant insertion when alveolar bone expansion is not planned because of the dome shape of the alveolar crest. To manage this situation a split crest technique has been proposed for alveolar bone expansion and the implants' insertion in one stage surgery...
January 2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28399529/in-utero-exposure-to-germinated-brown-rice-and-its-gaba-extract-attenuates-high-fat-diet-induced-insulin-resistance-in-rat-offspring
#18
Hadiza Altine Adamu, Mustapha Umar Imam, Ooi Der-Jiun, Maznah Ismail
BACKGROUND: Numerous studies have reported on the influence of diet on insulin resistance. Our study provides insight into the effect of germinated brown rice (GBR) and γ-aminobutyric acid (GABA) on early environment-driven programming and susceptibility to insulin resistance in rat offspring. METHODS: Male rat offspring from female Sprague-Dawley rats fed with a high-fat diet (HFD) alone, HFD + GBR, or HFD + GABA extract throughout pregnancy and lactation were weaned 4 weeks after delivery and followed up for 8 weeks...
April 12, 2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28378530/guided-bone-regeneration-with-particulate-vs-block-xenogenic-bone-substitutes-a-pilot-cone-beam-computed-tomographic-investigation
#19
Goran I Benic, Daniel S Thoma, Ronald E Jung, Ignacio M Sanz, Silvan Unger, Antonio Cantalapiedra, Christoph H F Hämmerle
AIM: To test whether an equine bone substitute block used for guided bone regeneration (GBR) of peri-implant defects differs from bovine block or particulate bone substitutes regarding the hard and soft tissue contours of the augmented ridge. MATERIAL & METHODS: Two semi-saddle bone defects were prepared in each side of the mandible of eight dogs, and one titanium implant was inserted into every defect. The defects were randomly allocated to receive one of the following treatments: bone augmentation by GBR using (1) particulate deproteinized bovine bone mineral (DBBM) + a collagen membrane (CM), (2) block DBBM + CM, (3) equine bone substitute block + CM, and (4) empty controls...
April 4, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28348238/evolving-polycentric-governance-of-the-great-barrier-reef
#20
Tiffany H Morrison
A growing field of sustainability science examines how environments are transformed through polycentric governance. However, many studies are only snapshot analyses of the initial design or the emergent structure of polycentric regimes. There is less systematic analysis of the longitudinal robustness of polycentric regimes. The problem of robustness is approached by focusing not only on the structure of a regime but also on its context and effectiveness. These dimensions are examined through a longitudinal analysis of the Great Barrier Reef (GBR) governance regime, drawing on in-depth interviews and demographic, economic, and employment data, as well as organizational records and participant observation...
April 11, 2017: Proceedings of the National Academy of Sciences of the United States of America
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