Matthieu Béreau, Astrid Kibleur, Mathieu Servant, Gautier Clément, Kathy Dujardin, Anne-Sophie Rolland, Thomas Wirth, Ouhaid Lagha-Boukbiza, Jimmy Voirin, Marie des Neiges Santin, Elodie Hainque, David Grabli, Alexandre Comte, Sophie Drapier, Franck Durif, Ana Marques, Alexandre Eusebio, Jean-Philippe Azulay, Caroline Giordana, Jean-Luc Houeto, Béchir Jarraya, David Maltete, Olivier Rascol, Tiphaine Rouaud, Mélissa Tir, Caroline Moreau, Teodor Danaila, Stéphane Prange, Laurent Tatu, Christine Tranchant, Jean-Christophe Corvol, David Devos, Stephane Thobois, Maxime Desmarets, Mathieu Anheim
Postoperative apathy is a frequent symptom in Parkinson's disease patients who have undergone bilateral deep brain stimulation of the subthalamic nucleus. Two main hypotheses for postoperative apathy have been suggested: i) dopaminergic withdrawal syndrome relative to postoperative dopaminergic drug tapering and ii) direct effect of chronic stimulation of the subthalamic nucleus. The primary objective of our study was to describe preoperative and one-year postoperative apathy in Parkinson's disease patients who underwent chronic bilateral deep brain stimulation of the subthalamic nucleus...
October 3, 2023: Brain