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https://www.readbyqxmd.com/read/27912743/str-realigner-a-realignment-method-for-short-tandem-repeat-regions
#1
Kaname Kojima, Yosuke Kawai, Kazuharu Misawa, Takahiro Mimori, Masao Nagasaki
BACKGROUND: In the estimation of repeat numbers in a short tandem repeat (STR) region from high-throughput sequencing data, two types of strategies are mainly taken: a strategy based on counting repeat patterns included in sequence reads spanning the region and a strategy based on estimating the difference between the actual insert size and the insert size inferred from paired-end reads. The quality of sequence alignment is crucial, especially in the former approaches although usual alignment methods have difficulty in STR regions due to insertions and deletions caused by the variations of repeat numbers...
December 3, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27903195/dosimetric-effects-of-onyx-embolization-on-gamma-knife-arteriovenous-malformation-dose-distributions
#2
David J Schlesinger, Håkan Nordström, Anders Lundin, Zhiyuan Xu, Jason P Sheehan
OBJECTIVE Patients with arteriovenous malformations (AVMs) treated with Gamma Knife radiosurgery (GKRS) subsequent to embolization suffer from elevated local failure rates and differences in adverse radiation effects. Onyx is a common embolic material for AVMs. Onyx is formulated with tantalum, a high atomic number (Z = 73) element that has been investigated as a source of dosimetric uncertainty contributing to the less favorable clinical results. However, prior studies have not modeled the complicated anatomical and beam geometries characteristic of GKRS...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27894610/-reconstruction-of-proximal-nasal-defect-after-deep-carcinological-resection-interest-to-combine-titane-mesh-with-fat-grafting
#3
R Aimard, C Lalloué, C Ho Quoc, D Girodet, P Zrounba, E Delay
INTRODUCTION: The mucosal cylindroma or adenoid cystic carcinoma is the second sinonasal non-epithelial malignant tumor frequency argument. Due to the achievement of the nasal mucosa and a late diagnosis reconstructions are often complex. We report the case of a mucous cylindroma recurrence of nasal septum requiring a wide and deep excision of the root of the nose with nasal reconstruction. CASE REPORT: A patient aged 66 years whose history resection two years ago with a mucous adenoid cystic carcinoma of the right side of the nasal septum, had a local recurrence T2NOM0 imposing a wide excision with amputation nasal septum own bones of nose, the anterior portion of the triangular cartilages...
November 25, 2016: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/27891263/coverage-root-after-removing-peripheral-ossifying-fibroma-5-year-follow-up-case-report
#4
Paulo S G Henriques, Luciana S Okajima, Marcelo P Nunes, Victor A M Montalli
When lesions in soft tissue reach the gingival margin, they can produce aesthetic defects during its permanence and after its removal. Periodontal plastic surgery allows the correction of the gingival contour using different techniques. This paper is a case report of a peripheral ossifying fibroma removal in the interproximal area of teeth 21 and 22 in addition to root coverage of the affected area through two surgical phases: keratinized gingival tissue augmentation surgery with free gingival graft concurrent with removal of the lesion and, in a second stage, root coverage by performing coronally advanced flap technique with a follow-up of five years...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27870054/a-plant-growth-form-dataset-for-the-new-world
#5
K Engemann, B Sandel, B Boyle, B J Enquist, P M Jørgensen, J Kattge, B J McGill, N Morueta-Holme, R K Peet, N J Spencer, C Violle, S K Wiser, J-C Svenning
This dataset provides growth form classifications for 67,413 vascular plant species from North, Central, and South America. The data used to determine growth form were compiled from five major integrated sources and two original publications: the Botanical Information and Ecology Network (BIEN), the Plant Trait Database (TRY), the SALVIAS database, the USDA PLANTS database, Missouri Botanical Garden's Tropicos database, Wright (2010), and Boyle (1996). We defined nine plant growth forms based on woodiness (woody or non-woody), shoot structure (self-supporting or not self-supporting), and root traits (rooted in soil, not rooted in soil, parasitic or aquatic): Epiphyte, Liana, Vine, Herb, Shrub, Tree, Parasite, or Aquatic...
November 2016: Ecology
https://www.readbyqxmd.com/read/27858261/soil-properties-and-species-composition-under-different-grazing-intensity-in-an-alpine-meadow-on-the-eastern-tibetan-plateau-china
#6
Zhen'an Yang, Wan Xiong, Yingyi Xu, Lin Jiang, Erxiong Zhu, Wei Zhan, Yixin He, Dan Zhu, Qiuan Zhu, Changhui Peng, Huai Chen
As the main form of land use and human disturbance of grassland, livestock grazing has great influences on the soil resources and plant communities. This study observed the variation of soil properties and community characteristics of four treatments of different grazing intensity (no grazing, UG; light grazing, LG; moderate grazing, MG; and heavy grazing, HG) in an alpine meadow of Sichuan Province on the northeastern margin of the Tibetan Plateau. The results showed that grazing increased the pH, soil bulk density (BD), and contents of total carbon (TC) and total nitrogen (TN), and the BD increased while the others decreased with the grazing intensity...
December 0: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27845923/the-tofts-model-in-frequency-domain-fast-and-robust-determination-of-pharmacokinetic-maps-for-dynamic-contrast-enhancement-mri
#7
Nithin N Vajuvalli, Dharmendra Kumar K Chikkemenahally, Krupa N Nayak, Manoj G Bhosale, Sairam Geethanath
Dynamic contrast enhancement magnetic resonance imaging (DCE-MRI) is a well-established method for non-invasive detection and therapeutic monitoring of pathologies through administration of intravenous contrast agent. Quantification of pharmacokinetic (PK) maps can be achieved through application of compartmental models relevant to the pathophysiology of the tissue under interrogation. The determination of PK parameters involves fitting of time-concentration data to these models. In this work, the Tofts model in frequency domain (TM-FD) is applied to a weakly vascularized tissue such as the breast...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27834120/2-year-assessment-of-tissue-bioestimulation-with-low-level-laser-on-the-outcomes-of-connective-tissue-graft-in-the-treatment-of-single-gingival-recession-randomized-clinical-trial
#8
Mauro Pedrine Santamaria, Stephanie Botti Fernandes-Dias, Cassia Fernandes Araújo, Felipe Lucas da Silva Neves, Ingrid Fernandes Mathias, Naira Maria Rebelato Bechara Andere, Maria Aparecida Neves Jardini
BACKGROUND: Periodontal wound healing has been accelerated by different low-level laser therapy (LLLT) protocols. However, just few studies evaluated the use of this therapy as adjunctive for periodontal plastic surgery procedures. The present study shows a 2-year result of connective tissue graft associated with LLLT in the treatment of gingival recession defects. METHODS: Forty patients presenting Miller Class I and II gingival recessions were previously treated by: Connective tissue graft (Control group, n = 20) or Connective tissue graft + LLLT (Test group, n = 20)...
November 11, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27829749/management-of-gingival-recession-with-acellular-dermal-matrix-graft-a-clinical-study
#9
V R Balaji, T Ramakrishnan, D Manikandan, R Lambodharan, B Karthikeyan, Thanvir Mohammed Niazi, G Ulaganathan
AIMS AND OBJECTIVES: Obtaining root coverage has become an important part of periodontal therapy. The aims of this studyare to evaluate the clinical efficacy of acellular dermal matrix graft in the coverage of denuded roots and also to examine the change in the width of keratinized gingiva. MATERIALS AND METHODS: A total of 20 sites with more than or equal to 2 mm of recession depth were taken into the study, for treatment with acellular dermal matrix graft. The clinical parameters such as recession depth, recession width, width of keratinized gingiva, probing pocket depth (PD), and clinical attachment level (CAL) were measured at the baseline, 8(th) week, and at the end of the study (16(th) week)...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27809762/transcriptome-analysis-of-the-fungal-pathogen-fusarium-oxysporum-f-sp-medicaginis-during-colonisation-of-resistant-and-susceptible-medicago-truncatula-hosts-identifies-differential-pathogenicity-profiles-and-novel-candidate-effectors
#10
Louise F Thatcher, Angela H Williams, Gagan Garg, Sally-Anne G Buck, Karam B Singh
BACKGROUND: Pathogenic members of the Fusarium oxysporum species complex are responsible for vascular wilt disease on many important crops including legumes, where they can be one of the most destructive disease causing necrotrophic fungi. We previously developed a model legume-infecting pathosystem based on the reference legume Medicago truncatula and a pathogenic F. oxysporum forma specialis (f. sp.) medicaginis (Fom). To dissect the molecular pathogenicity arsenal used by this root-infecting pathogen, we sequenced its transcriptome during infection of a susceptible and resistant host accession...
November 3, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27794230/dune-scale-distribution-pattern-of-herbaceous-plants-and-their-relationship-with-environmental-factors-in-a-saline-alkali-desert-in-central-asia
#11
Ye Tao, Gan-Lin Wu, Yuan-Ming Zhang
Sand dunes are the main landforms in modern deserts worldwide. As an important type of desert vegetation, herbaceous plants have long been acknowledged for their important ecological functions. We focus on the dune-scale distribution pattern of herbaceous plants and their relationship with the environment. During the early summer of 2010, the herbaceous plant density, coverage, aboveground biomass and eighteen environmental factors were surveyed from 214 plots (5m×5m) across two linear sand dunes (220m×110m) located in the Gurbantunggut Desert, China, a typical saline-alkali desert in Central Asia...
October 26, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27790732/root-coverage-using-porcine-collagen-matrix-with-fibroblast-growth-factor-2-a-pilot-study-in-dogs
#12
Jae Kook Cha, Yoo-Kyung Sun, Jung-Seok Lee, Seong-Ho Choi, Ui-Won Jung
AIM: The aim of this study was to evaluate the effect of fibroblast growth factor-2 (FGF-2) in combination with porcine collagen matrix (CM) for coverage of gingival recession defects in dogs. MATERIALS AND METHODS: In five male mongrel dogs, labial gingival recession defects were surgically created in the lower-third incisors bilaterally. The defects were randomly assigned to the CM/FGF-2 group (experimental) or the CM-only group (control). Standardized clinical photographs and silicone impressions were taken at 4 and 16 weeks of healing to calculate the remaining recession area...
October 28, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27785153/developing-a-modular-architecture-for-creation-of-rule-based-clinical-diagnostic-criteria
#13
Na Hong, Jyotishman Pathak, Christopher G Chute, Guoqian Jiang
BACKGROUND: With recent advances in computerized patient records system, there is an urgent need for producing computable and standards-based clinical diagnostic criteria. Notably, constructing rule-based clinical diagnosis criteria has become one of the goals in the International Classification of Diseases (ICD)-11 revision. However, few studies have been done in building a unified architecture to support the need for diagnostic criteria computerization. In this study, we present a modular architecture for enabling the creation of rule-based clinical diagnostic criteria leveraging Semantic Web technologies...
2016: BioData Mining
https://www.readbyqxmd.com/read/27783851/regenerative-potential-of-leucocyte-and-platelet-rich-fibrin-part-a-intra-bony-defects-furcation-defects-and-periodontal-plastic-surgery-a-systematic-review-and-meta-analysis
#14
REVIEW
Ana B Castro, Nastaran Meschi, Andy Temmerman, Nelson Pinto, Paul Lambrechts, Wim Teughels, Marc Quirynen
AIM: To analyse the regenerative potential of leucocyte- and platelet-rich fibrin (L-PRF) during periodontal surgery. MATERIALS AND METHODS: An electronic and hand search were conducted in three databases. Only randomized clinical trials were selected and no follow-up limitation was applied. Pocket depth (PD), clinical attachment level (CAL), bone fill, keratinized tissue width (KTW), recession reduction and root coverage (%) were considered as outcome. When possible, meta-analysis was performed...
October 26, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27761392/periosteum-as-a-lateral-pedicle-graft-for-the-treatment-of-single-tooth-root-recession-a-novel-approach
#15
Avadhesh Kumar, Shalini Kaushal, Neelu Verma, Deepti Chandra
The treatment of gingival recession defects is indicated for esthetic and functional reasons to reduce root sensitivity, to remove muscle pull, to create or augment keratinized tissue, and to prevent disease progression. The presence of sufficient amount of periosteum adjacent to gingival recession defects makes it a suitable graft. The adult human periosteum is a highly vascular connective tissue with immense regenerative potential. It contains fibroblasts, osteogenic progenitor cells, and stem cells as a result of which it has the ability to differentiate into fibroblast, osteoblast, chondrocytes, adipocytes, and skeletal myocytes...
September 2016: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/27760173/filtration-and-normalization-of-sequencing-read-data-in-whole-metagenome-shotgun-samples
#16
Philippe Chouvarine, Lutz Wiehlmann, Patricia Moran Losada, David S DeLuca, Burkhard Tümmler
Ever-increasing affordability of next-generation sequencing makes whole-metagenome sequencing an attractive alternative to traditional 16S rDNA, RFLP, or culturing approaches for the analysis of microbiome samples. The advantage of whole-metagenome sequencing is that it allows direct inference of the metabolic capacity and physiological features of the studied metagenome without reliance on the knowledge of genotypes and phenotypes of the members of the bacterial community. It also makes it possible to overcome problems of 16S rDNA sequencing, such as unknown copy number of the 16S gene and lack of sufficient sequence similarity of the "universal" 16S primers to some of the target 16S genes...
2016: PloS One
https://www.readbyqxmd.com/read/27754322/reduction-of-kinematic-short-baseline-multipath-effects-based-on-multipath-hemispherical-map
#17
Miaomiao Cai, Wen Chen, Danan Dong, Le Song, Minghua Wang, Zhiren Wang, Feng Zhou, Zhengqi Zheng, Chao Yu
Multipath hemispherical map (MHM) is a kind of multipath mitigation approach that takes advantage of the spatial repeatability of the multipath effect under an unchanged environment. This approach is not only suitable for static environments, but also for some kinematic platforms, such as a moving ship and airplane, where the dominant multipath effects come from the platform itself and the multipath effects from the surrounding environment are considered minor or negligible. Previous studies have verified the feasibility of the MHM approach in static environments...
October 12, 2016: Sensors
https://www.readbyqxmd.com/read/27740648/coverage-of-multiple-mandibular-gingival-recessions-using-tunnel-technique-with-connective-tissue-graft-a-prospective-case-series
#18
Tobias Thalmair, Stefan Fickl, Hannes Wachtel
The aim of this clinical case series was to evaluate the clinical performance of the modified tunnel technique for treatment of multiple gingival recessions in the anterior mandible. A total of 20 patients with 63 Miller Class I and II defects were treated via a modified tunnel technique with subepithelial connective tissue graft. At baseline and 6 months postoperative, recession depth, probing pocket depth, width of keratinized tissue, and gingival tissue thickness were assessed. At 6 months, the results revealed a mean recession coverage of 93...
November 2016: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/27740647/combined-regenerative-and-mucogingival-treatment-of-deep-intrabony-defects-associated-with-buccal-gingival-recession-two-case-reports
#19
Giacomo Santoro, Giovanni Zucchelli, Enrico Gherlone
The case reports presented in this article describe a surgical approach for improving root coverage and regenerative parameters in deep intrabony defects associated with buccal gingival recession. A mandibular canine and a maxillary premolar were treated. The surgical technique consisted of a connective tissue graft (CTG) that was placed and sutured at the inner surface of a coronally advanced envelope flap (CAF), thickening the buccal soft tissue wall of the most coronal extension of the intrabony defect and treated with biomaterials as scaffold...
November 2016: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/27736792/accurate-estimation-of-fungal-diversity-and-abundance-through-improved-lineage-specific-primers-optimized-for-illumina-amplicon-sequencing
#20
D Lee Taylor, William A Walters, Niall J Lennon, James Bochicchio, Andrew Krohn, J Gregory Caporaso, Taina Pennanen
: While high-throughput sequencing methods are revolutionizing fungal ecology, recovering accurate estimates of species richness and abundance has proven elusive. We sought to design internal transcribed spacer (ITS) primers and an Illumina protocol that would maximize coverage of the kingdom Fungi while minimizing nontarget eukaryotes. We inspected alignments of the 5.8S and large subunit (LSU) ribosomal genes and evaluated potential primers using PrimerProspector. We tested the resulting primers using tiered-abundance mock communities and five previously characterized soil samples...
December 15, 2016: Applied and Environmental Microbiology
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