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https://www.readbyqxmd.com/read/27891518/size-and-proportions-of-slow-twitch-and-fast-twitch-muscle-fibers-in-human-costal-diaphragm
#1
Marija Meznaric, Erika Cvetko
Smaller diaphragmatic motor unit potentials (MUPs) compared to MUPs of limb muscles lead to the hypothesis that diaphragmatic muscle fibers, being the generators of MUPs, might be also smaller. We compared autopsy samples of costal diaphragm and vastus lateralis of healthy men with respect to fibers' size and expression of slow myosin heavy chain isoform (MyHC-1) and fast 2A isoform (MyHC-2A). Diaphragmatic fibers were smaller than fibers in vastus lateralis with regard to the mean minimal fiber diameter of slow-twitch (46...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27771429/total-knee-implant-posterior-stabilised-by-a-third-condyle-design-evolution-and-post-operative-complications
#2
R Gaillard, S Lustig, A Peltier, V Villa, E Servien, P Neyret
BACKGROUND: Despite excellent long-term outcomes, posterior stabilisation by a third condyle continues to receive unwarranted criticism regarding patellar complications and instability. HYPOTHESIS: Complication rates with a tri-condylar posterior-stabilised implant are similar to those with other posterior-stabilised prostheses and have diminished over time due to improvements in prosthesis design. MATERIAL AND METHODS: Post-operative complications and revision rates were assessed retrospectively in a prospective cohort of 4189 consecutive patients who had primary total knee arthroplasty (TKA) using a tri-condylar posterior-stabilised implant (Wright-Tornier) and were then followed-up for at least 24 months...
October 19, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27722504/autonomous-microfluidic-capillaric-circuits-replicated-from-3d-printed-molds
#3
A O Olanrewaju, A Robillard, M Dagher, D Juncker
We recently developed capillaric circuits (CCs) - advanced capillary microfluidic devices assembled from capillary fluidic elements in a modular manner similar to the design of electric circuits (Safavieh & Juncker, Lab Chip, 2013, 13, 4180-4189). CCs choreograph liquid delivery operations according to pre-programmed capillary pressure differences with minimal user intervention. CCs were thought to require high-precision micron-scale features manufactured by conventional photolithography, which is slow and expensive...
September 21, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27681698/association-between-polymorphisms-of-ogg1-epha2-and-age-related-cataract-risk-a-meta-analysis
#4
Hongxu Zhang, Jianguang Zhong, Zhenyu Bian, Xiang Fang, You Peng, Yongping Hu
BACKGROUND: Evidences have identified the correlation of 8-oxoguanine DNA glycosylase-1 (OGG1) and eph-receptor tyrosine kinase-type A2 (EPHA2) polymorphisms in age-related cataract (ARC) risk. However, the results were not consistent. The objective of this study was to examine the role of these two gene polymorphisms in ARC susceptibility. METHODS: Eligible case-control studies published between January 2000 and 2015 were searched and retrieved in the electronic databases...
September 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27461017/the-impact-of-depot-medroxyprogesterone-acetate-on-fracture-risk-a-case-control-study-from-the-uk
#5
I Kyvernitakis, K Kostev, T Nassour, F Thomasius, P Hadji
: There has been concerning about women receiving depot medroxyprogesterone acetate (DMPA) contraception because of the prolonged hypoestrogenemic state regarding the potential negative effects on bone health. This study showed that DMPA exposure is associated with increased fracture risk and that fracture risk increases with longer DMPA exposure. INTRODUCTION: DMPA has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life...
July 26, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27173217/association-of-beclin-1-and-microrna-30a-expression-with-the-severity-and-treatment-response-of-colorectal-cancer
#6
L Liu, T Meng, Q S Wang, H Z Jin, Z Q Sun, B Jin, F Fang, H J Wang
We investigated the associations between Beclin-1 and microRNA-30a (miR-30a) expression and the severity and treatment response in colorectal cancer (CRC). Our sample size consisted of 139 CRC patients who were treated with surgery alone. Immunohistochemistry was used to investigate the expression and prognostic significance of Beclin-1 in CRC, while the weak expression of Beclin-1 in normal tissue was used as the basis for assessing tumors (control group). Real-time reverse transcription-polymerase chain reaction quantified miR-30a levels...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27063410/genetic-diversity-of-leishmania-tropica-strains-isolated-from-clinical-forms-of-cutaneous-leishmaniasis-in-rural-districts-of-herat-province-western-afghanistan-based-on-its1-rdna
#7
Mahdi Fakhar, Hossein Pazoki Ghohe, Sayed Abobakar Rasooli, Mehdi Karamian, Abdul Satar Mohib, Hajar Ziaei Hezarjaribi, Abdol Sattar Pagheh, Mohammad Amin Ghatee
Despite the high incidence of cutaneous leishmaniasis (CL) in Afghanistan, there is a little information concerning epidemiological status of the disease and phylogenetic relationship and population structure of causative agents. This study was conducted to determine the prevalence and distribution of CL cases and investigate the Leishmania tropica population structure in rural districts of Heart province in the West of Afghanistan in comparison to neighboring foci. Overall, 4189 clinically suspected CL cases from 177 villages (including 12 districts) in Herat province were enrolled in the referral laboratory of WHO sub-office in Herat city from January 2012 to December 2013...
July 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27009910/post-acute-referral-of-stroke-victims-in-a-french-urban-area-results-of-a-specific-program
#8
H Cassoudesalle, A Nozères, H Petit, V Cressot, F Muller, F Rouanet, I Sibon, P-A Joseph, P Dehail
OBJECTIVE: The main objective of this study was to describe the distribution of referrals offered to patients assessed in the "Post-Acute Stroke program" of Bordeaux University Hospital (France). This program was developed in 2008 to organize the dispensation of care in rehabilitation units specialized in neurological diseases. MATERIAL AND METHODS: This was a single-centre observational study. Between July 2008 and December 2012, data on the number of stroke patients hospitalized at the Bordeaux University Hospital and their post-acute referral were collected from the local hospital discharge database...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/26602922/identification-of-pathogenicity-related-genes-in-biofilm-defective-acidovorax-citrulli-by-transposon-tn5-mutagenesis
#9
Jinyan Luo, Wen Qiu, Lei Chen, Syed Ishtiaq Anjum, Menghao Yu, Changlin Shan, Mehmoona Ilyas, Bin Li, Yanli Wang, Guochang Sun
Biofilm formation is important for virulence of a large number of plant pathogenic bacteria. Indeed, some virulence genes have been found to be involved in the formation of biofilm in bacterial fruit blotch pathogen Acidovorax citrulli. However, some virulent strains of A. citrulli were unable to format biofilm, indicating the complexity between biofilm formation and virulence. In this study, virulence-related genes were identified in the biofilm-defective strain A1 of A. citrulli by using Tn5 insertion, pathogenicity test, and high-efficiency thermal asymmetric interlaced PCR (hiTAIL-PCR)...
2015: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/26384063/gestational-weight-gain-and-risks-for-adverse-perinatal-outcomes-a-retrospective-cohort-study-based-on-the-2009-institute-of-medicine-guidelines
#10
COMPARATIVE STUDY
Tai-Ho Hung, Szu-Fu Chen, Jenn-Jeih Hsu, T'sang-T'ang Hsieh
OBJECTIVE: To investigate perinatal outcomes according to the 2009 Institute of Medicine (IOM) gestational weight gain (GWG) guidelines. MATERIALS AND METHODS: A retrospective cohort study was conducted among all term, singleton, live births to women who delivered at the Taipei Chang Gung Memorial Hospital, Taipei, Taiwan between 2009 and 2014. Women were categorized into three groups based on prepregnancy body mass index and GWG relative to the IOM guidelines. Multivariable logistic regression analysis was used to assess the associations between GWG outside the IOM guidelines and adverse perinatal outcomes...
August 2015: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26345888/assessment-of-genotoxicity-of-waterpipe-smoking-using-8-ohdg-biomarker
#11
M Azab, O F Khabour, K H Alzoubi, S A H Mahmoud, M Anabtawi, M Quttina
Waterpipe tobacco smoking is increasing in popularity, particularly among young adults. This popularity is related to the lack knowledge regarding the health effects of waterpipe smoking. In this study, we examined the genotoxicity of waterpipe smoking using an 8-hydroxy deoxyguanosine (8-OHdG) assay. Genotoxicity was evaluated in the saliva, urine, and serum of 66 waterpipe adult smokers and 46 healthy nonsmokers. The level of addiction to waterpipe smoking was evaluated using the Lebanon Waterpipe Dependence Scale-11...
2015: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/26314109/-characteristics-of-atmospheric-nitrogen-wet-deposition-and-associated-impact-on-n-transport-in-the-watershed-of-red-soil-area-in-southern-china
#12
Zhuo Hao, Yang Gao, Jin-zhong Zhang, Ya-juan Xu, Gui-rui Yu
In this study, Qianyanzhou Xiangxi River Basin in the rainy season was monitored to measure different nitrogen form concentrations of rainfall and rainfall-runoff process, in order to explore the southern red soil region of nitrogen wet deposition characteristics and its influence on N output in watershed. The results showed that there were 27 times rainfall in the 2014 rainy season, wherein N wet deposition load reached 43.64-630.59 kg and N deposition flux were 0.44-6.43 kg · hm(-2), which presented a great seasonal variability...
May 2015: Huan Jing Ke Xue= Huanjing Kexue
https://www.readbyqxmd.com/read/26186526/domestication-as-a-novel-approach-for-improving-the-cultivation-of-calanoid-copepods-a-case-study-with-parvocalanus-crassirostris
#13
Fahad Alajmi, Chaoshu Zeng, Dean R Jerry
Calanoid copepods are an important food source for most fish larvae. Their role as a natural prey item means that it is important to develop culture technology for copepods to meet the requirements of larvae culture in aquaculture hatcheries. Copepods have been cultured successfully for some time; however, the implications of long-term cultivation or domestication on copepod life history traits have not yet been assessed. Therefore, the aim of this study was to determine if the domesticated and wild populations of Parvocalanus crassirostris are phenotypically or physiologically different...
2015: PloS One
https://www.readbyqxmd.com/read/25572276/risk-factors-for-postoperative-intra-abdominal-septic-complications-after-surgery-in-crohn-s-disease-a-meta-analysis-of-observational-studies
#14
REVIEW
Wenpeng Huang, Yanbo Tang, Legen Nong, Yifan Sun
BACKGROUND AND AIMS: Postoperative intra-abdominal septic complications [IASCs] are the most feared risks of surgery for Crohn's disease[CD]. The risk factors for IASCs still remain controversial. The aim of this study was to assess the risk factors for IASCs in CD patients undergoing abdominal surgery. METHODS: MEDLINE, Cochrane Library, and EMBASE were searched to identify observational studies reporting the risk factors for IASCs in CD patients. A meta-analysis was conducted to investigate the impact of various risk factors on IASCs in CD...
March 2015: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/25372355/determination-of-the-persistence-of-dimetridazole-metronidazole-and-ronidazole-residues-in-black-tiger-shrimp-penaeus-monodon-tissue-and-their-stability-during-cooking
#15
Anna Gadaj, Kevin M Cooper, Nitsara Karoonuthaisiri, Ambrose Furey, Martin Danaher
The depletion of three banned nitroimidazole drugs - dimetridazole (DMZ), metronidazole (MNZ) and ronidazole (RNZ) - was investigated in black tiger shrimp (Penaeus monodon) following in-water medication. The highest concentrations of residues were measured immediately after the 24-h immersion (d0). At this time, MNZ and MNZ-OH residues were measured in shrimp tissue samples at concentrations ranging from 361 to 4189 and from 0.28 to 6.6 μg kg(-1), respectively. DMZ and its metabolites HMMNI ranged in concentration between 31,509 and 37,780 and between 15...
2015: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/25146298/a-meta-analysis-of-prevalence-rates-and-moderating-factors-for-cancer-related-post-traumatic-stress-disorder
#16
Gareth Abbey, Simon B N Thompson, Tamas Hickish, David Heathcote
OBJECTIVE: Systematic reviews highlight a broad range of cancer-related post-traumatic stress disorder (CR-PTSD) prevalence estimates in cancer survivors. This meta-analysis was conducted to provide a prevalence estimate of significant CR-PTSD symptoms and full diagnoses to facilitate the psychological aftercare of cancer survivors. METHODS: A systematic literature search was conducted for studies using samples of cancer survivors by using validated clinical interviews and questionnaires to assess the prevalence of CR-PTSD (k = 25, n = 4189)...
April 2015: Psycho-oncology
https://www.readbyqxmd.com/read/24993449/safety-and-efficacy-of-tandem-hemodialysis-and-plasma-exchange-in-children
#17
COMPARATIVE STUDY
Betti Schaefer, Akos Ujszaszi, Susanne Schaefer, Karl Heinz Heckert, Franz Schaefer, Claus Peter Schmitt
BACKGROUND AND OBJECTIVES: Patients with immune-mediated kidney disease and liver failure often require plasma exchange (PE) and hemodialysis (HD). Combining both methods (i.e., connecting the PE and HD circuits in series [tandem dialysis]) should allow for a more efficient treatment. This work reviews the authors' experience with tandem blood purification. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Chart review was utilized to retrospectively analyze the efficacy and tolerability of 92 combined PE/HD (cPE/HD) sessions in 26 children in comparison with 113 sequential PE/HD (sPE/HD) treatments performed in 32 children between 1988 and 2012 at the University of Heidelberg Center for Pediatric and Adolescent Medicine...
September 5, 2014: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/24594775/early-hospital-mortality-among-adult-trauma-patients-significantly-declined-between-1998-2011-three-single-centre-cohorts-from-mumbai-india
#18
Martin Gerdin, Nobhojit Roy, Satish Dharap, Vineet Kumar, Monty Khajanchi, Göran Tomson, Li Felländer Tsai, Max Petzold, Johan von Schreeb
BACKGROUND: Traumatic injury causes more than five million deaths each year of which about 90% occur in low- and middle-income countries (LMIC). Hospital trauma mortality has been significantly reduced in high-income countries, but to what extent similar results have been achieved in LMIC has not been studied in detail. Here, we assessed if early hospital mortality in patients with trauma has changed over time in an urban lower middle-income setting. METHODS: We conducted a retrospective study of patients admitted due to trauma in 1998, 2002, and 2011 to a large public hospital in Mumbai, India...
2014: PloS One
https://www.readbyqxmd.com/read/24129319/freeway-safety-estimation-using-extreme-value-theory-approaches-a-comparative-study
#19
COMPARATIVE STUDY
Lai Zheng, Karim Ismail, Xianghai Meng
The validity of traffic conflicts and other surrogate events has been a great concern in the development and application of surrogate safety measures. Extreme value theory (EVT) offers a strong modeling framework for linking surrogate measures of safety to crash frequency. This study aims at developing, validating, and comparing two EVT modeling approaches for characterizing extreme events. The two alternative EVT approaches, block maxima (BM) and peak over threshold (POT), are used to relate surrogates and lane change maneuver-related crashes on freeways...
January 2014: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/23785400/pharmacokinetics-study-of-recombinant-hirudin-in-the-plasma-of-rats-using-chromogenic-substrate-elisa-and-radioisotope-assays
#20
Su-Yun Jiang, Jian Jiao, Ting-Ting Zhang, Yong-Ping Xu
AIM: To compare the analytical methods used to study the pharmacokinetics of recombinant hirudin in the plasma of rats that had been injected with (125)I-recombinant hirudin. METHODS: 2.0 mg/kg (125)I-recombinant hirudin were injected intravenously into rats. The recombinant hirudins in the plasma was analyzed by chromogenic substrate assay, enzyme-linked immunosorbent assay (ELISA), total radioisotope assay (RA) and trichloroacetic acid pre-treated total radioisotope assay (TCA-RA)...
2013: PloS One
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