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neonatal developmental care

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https://www.readbyqxmd.com/read/30021468/effect-of-maternal-psychopathology-on-neurodevelopmental-outcome-and-quality-of-the-dyadic-relationship-in-preterm-infants-an-explorative-study
#1
C Pisoni, S Spairani, F Fauci, G Ariaudo, C Tzialla, C Tinelli, P Politi, U Balottin, M Stronati, S Orcesi
BACKGROUND: The literature shows that parents of preterm infants are at risk of psychological distress and that this may impact on the quality of the parent-child relationship and on the child's development. AIM: This longitudinal study was conducted to examine in preterm infants relationships between maternal psychological variables, parental protective factors, perinatal infant variables, and neurodevelopmental outcome. Furthermore, we explored the impact of these variables on the quality of the mother-infant relationship (dyadic synchrony)...
July 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30010451/the-prognosis-of-infants-with-neonatal-respiratory-inhibition-syndrome
#2
Hideki Minowa, Kumiko Takagi, Ikuyo Arai, Hajime Yasuhara, Reiko Ebisu, Ayako Ohgitani
OBJECTIVE: The goal of this study was to investigate the prognosis of infants with neonatal respiratory inhibition syndrome (NRIS). METHODS: Infants with a gestational age of at least 36 weeks and a birth weight of at least 2000 grams who were born at Nara Prefecture General Medical Center, in Nara, Japan, between March 2013 and June 2016 were screened for NRIS using our established method. NRIS was defined as severe hypoxemia caused by respiratory inhibition immediately after crying (RIAC) or gastroesophageal reflux (RIGER) or as a respiratory pause during feeding (feeding hypoxemia), accompanied clinically by central cyanosis and a decrease in SpO2 to less than 70%...
July 16, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29989087/breastfeeding-self-efficacy-and-breastmilk-feeding-for-moderate-and-late-preterm-infants-in-the-family-integrated-care-trial-a-mixed-methods-protocol
#3
Meredith Brockway, Karen M Benzies, Eloise Carr, Khalid Aziz
Background: Breastmilk is the ideal nutrition for preterm infants. Yet, breastmilk feeding rates among preterm infants are substantially lower than those of full-term infants. Barriers incurred through hospital care practices as well as the physical environment of the neonatal intensive care unit (NICU) can result in physical and emotional separation of infants from their parents, posing a substantial risk to establishing and maintaining breastfeeding. Additionally, current practitioner-focused care provision in the NICU can result in decreased breastfeeding self-efficacy (BSE), which is predictive of breastfeeding rates in mothers of preterm infants at 6 weeks postpartum...
2018: International Breastfeeding Journal
https://www.readbyqxmd.com/read/29980223/semilobar-holoprosencephaly-with-cebocephaly-associated-with-maternal-early-onset-preeclampsia-a-case-report
#4
Ahmed Amdihun Essa, Lakachew Asrade Feleke, Dawed Muhammed Ahmed
BACKGROUND: The term holoprosencephaly was proposed by DeMyer and Zeman. It is a developmental defect of the embryonic forebrain with heterogeneous etiology including genetic and environmental factors. It is commonly associated with midfacial defects and has a spectrum of presentations. There are four types: alobar, semilobar, lobar, and variant. Holoprosencephaly is relatively rare. The overall prevalence in a multicenter study was 1 in 13,000 to 18,000 live births. However, the presentation of holoprosencephaly with cebocephaly, micropenis, agenesis of middle phalanges of the fifth finger, and postaxial polydactyly in association with early onset preeclampsia is extremely rare...
July 7, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29966515/newborn-weight-change-and-childhood-cardio-metabolic-traits-a-prospective-cohort-study
#5
Maria João Fonseca, Milton Severo, Debbie A Lawlor, Henrique Barros, Ana Cristina Santos
BACKGROUND: Newborn weight change (NWC) in the first 4 days represents short-term adaptations to external environment. It may be a key developmental period for future cardio-metabolic health, but this has not been explored. We aimed to determine the associations of NWC with childhood cardio-metabolic traits. METHODS: As part of Generation XXI birth cohort, children were recruited in 2005/2006 at all public units providing obstetrical and neonatal care in Porto...
July 2, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29966208/perinatal-asphyxia-in-a-rural-nigerian-hospital-incidence-and-determinants-of-early-outcome
#6
O I Egharevba, B O Kayode-Adedeji, S O Alikah
BACKGROUND: Perinatal asphyxia is an important cause of morbidity and mortality in the neonatal period, accounting for 20-30% of neonatal mortality. A substantial proportion (estimated at 26%) of the 1 million annual intrapartum stillbirths result from asphyxia. Probably higher than the mortality is the plethora of morbidity associated with asphyxia, especially long term neuro-developmental problems including cerebral palsy.The real burden of perinatal asphyxia is difficult to establish because of paucity of information from the rural communities where the majority of neonatal morbidity and deaths occur...
June 23, 2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29927553/computational-analysis-of-neonatal-mouse-ultrasonic-vocalization
#7
Pilib Ó Broin, Michael V Beckert, Tomohisa Takahashi, Takeshi Izumi, Kenny Ye, Gina Kang, Patricia Pouso, Mackenzie Topolski, Jose L Pena, Noboru Hiroi
Neonatal vocalization is structurally altered in mouse models of autism spectrum disorder (ASD). Our published data showed that pup vocalization, under conditions of maternal separation, contains sequences whose alterations in a genetic mouse model of ASD impair social communication between pups and mothers. We describe details of a method which reveals the statistical structure of call sequences that are functionally critical for optimal maternal care. Entropy analysis determines the degree of non-random call sequencing...
June 2018: Current Protocols in Mouse Biology
https://www.readbyqxmd.com/read/29925339/maternal-overweight-is-not-an-independent-risk-factor-for-increased-birth-weight-leptin-and-insulin-in-newborns-of-gestational-diabetic-women-observations-from-the-prospective-each-cohort-study
#8
Raffael Ott, Jens H Stupin, Andrea Loui, Elisabeth Eilers, Kerstin Melchior, Rebecca C Rancourt, Karen Schellong, Thomas Ziska, Joachim W Dudenhausen, Wolfgang Henrich, Andreas Plagemann
BACKGROUND: Both gestational diabetes mellitus (GDM) as well as overweight/obesity during pregnancy are risk factors for detrimental anthropometric and hormonal neonatal outcomes, identified to 'program' adverse health predispositions later on. While overweight/obesity are major determinants of GDM, independent effects on critical birth outcomes remain unclear. Thus, the aim of the present study was to evaluate, in women with GDM, the relative/independent impact of overweight/obesity vs...
June 20, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29925276/exploring-the-impact-of-a-dual-occupancy-neonatal-intensive-care-unit-on-staff-workflow-activity-and-their-perceptions
#9
Margaret Broom, Zsuzsoka Kecskes, Sue Kildea, Anne Gardner
In 2012, a tertiary neonatal intensive care unit (NICU) transitioned from an open plan (OP) to a dual occupancy (DO) NICU. The DO design aimed to provide a developmental appropriate, family-centered environment for neonates and their families. During planning, staff questioned the impact DO would have on staff workflow and activity. To explore the impact of changing from an OP to a DO NICU, a prospective longitudinal study was undertaken from 2011 to 2014, using observational, time and motion, and surveys methods...
January 1, 2018: HERD
https://www.readbyqxmd.com/read/29922135/music-from-the-very-beginning-a-neuroscience-based-framework-for-music-as-therapy-for-preterm-infants-and-their-parents
#10
Friederike Barbara Haslbeck, Dirk Bassler
Human and animal studies demonstrate that early auditory experiences influence brain development. The findings are particularly crucial following preterm birth as the plasticity of auditory regions, and cortex development are heavily dependent on the quality of auditory stimulation. Brain maturation in preterm infants may be affected among other things by the overwhelming auditory environment of the neonatal intensive care unit (NICU). Conversely, auditory deprivation, (e.g., the lack of the regular intrauterine rhythms of the maternal heartbeat and the maternal voice) may also have an impact on brain maturation...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29921737/selection-bias-and-outcomes-for-preterm-neonates
#11
Kerryn Atwell, Emily Callander, Daniel Lindsay, Peter Blake Marshall, Scott Adam Morris
BACKGROUND: Reported survival and neurodevelopmental outcomes at 23 weeks' gestation are based on the infants admitted to NICUs. In this study, we aim to describe the association between clinical characteristics and admission to NICU at 23, 24 and 25 weeks' gestation. METHODS: Cohort data from 2 national databases enabled comparison of the clinical characteristics all Australian births and all NICU admissions during 2010-2013 at 23, 24, and 25 weeks' gestation. RESULTS: NICU admission occurred in 15% of all births at 23 weeks, in comparison with 49% at 24 weeks and 64% at 25 weeks...
June 19, 2018: Pediatrics
https://www.readbyqxmd.com/read/29893624/developmental-disorders-and-medical-complications-among-infants-with-subclinical-intrauterine-opioid-exposures
#12
Eric S Hall, Jennifer M McAllister, Scott L Wexelblatt
The objective was to compare diagnosis rates representing developmental outcomes and medical complications between infants with intrauterine opioid exposures who did not receive pharmacologic treatment for neonatal abstinence syndrome at the time of birth and infants for whom no exposure to substances of abuse were detected. This retrospective, descriptive study included approximately 95% of Hamilton County, Ohio resident births in 2014 and 2015. Universal maternal drug test results, performed at the time of birth, were documented and linked to electronic health records representing pediatric primary and subspecialty follow-up care as well as urgent care, emergency care, and inpatient services provided by Cincinnati Children's Hospital Medical Center through 2017, when all children were at least 24 months old...
June 12, 2018: Population Health Management
https://www.readbyqxmd.com/read/29890862/improving-diaper-performance-for-extremely-low-birth-weight-infants
#13
Veronica Sanchez, Michelle Maladen-Percy, Jennifer Gustin, Amy Tally, Roger Gibb, Julie Ogle, Dianna C Kenneally, Andrew N Carr
BACKGROUND: Extremely low-birth-weight (ELBW) infants face significant diapering challenges compared with their full-term peers, due to immature musculature, nervous system, and skin development. Advances in medical care have increased an ELBW infant's rate of survival, which creates a growing need for diapers to better serve these infants. Aim of research. The objective of this study was to identify and confirm the requirements for optimal diaper performance from the neonatal intensive care unit nurses' perspective, as well as to assess in-hospital performance to determine if new features improved key developmental care parameters...
August 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/29890513/summary-protocol-for-a-multi-centre-randomised-controlled-trial-of-enteral-lactoferrin-supplementation-in-newborn-very-preterm-infants-elfin
#14
(no author information available yet)
In a multi-centre randomised controlled trial (RCT), we are assessing whether giving very preterm (i.e., born at < 32 weeks' gestation) infants prophylactic enteral bovine lactoferrin supplementation (150 mg/kg/day) from shortly after birth until 34 weeks' post-menstrual age reduces the incidence of late-onset invasive infection (primary outcome), all-cause mortality, bronchopulmonary dysplasia, necrotising enterocolitis, retinopathy of prematurity, and the duration of antibiotic exposure, intensive care, and hospital admission...
June 11, 2018: Neonatology
https://www.readbyqxmd.com/read/29889471/-perinatal-stroke-from-symptoms-to-follow-up
#15
Eszter Vojcek, Márta Csécsei, Edina Flach, Gábor Rudas, Rózsa Gráf, Erzsébet Princzkel
Background and purpose: We aimed to analyze patient characteristics of term neonates with the diagnosis of stroke between 2006 and 2017 at the 3rd level Neonatal Intensive Care Unit of the Szent János Hospital. Methods: We conducted a retrospective and prospective analysis including 18 newborns with stroke. Presentation, imaging methods, etiology and clinical context were discussed. All patients had a follow-up at 2 years of age or later. Subject of the study - In the past 10 years 17 term born and one premature neonate born at 36 weeks of age were diagnosed with stroke in our unit...
March 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29884243/ocular-abnormalities-in-congenital-zika-syndrome-a-case-report-and-review-of-the-literature
#16
Jade Gieseke Guevara, Swati Agarwal-Sinha
BACKGROUND: As the number of children with Zika virus-related complications grows, the long-term developmental trajectory and its effects on families are unknown. We present the first known case of congenital Zika syndrome seen at our institution with significant fundus findings. CASE PRESENTATION: A 3-day-old Hispanic baby girl presented with severe microcephaly of 24 cm and temperature instability at birth. Her mother had traveled to Honduras early in pregnancy and testing of amniotic fluid was positive for Zika virus via polymerase chain reaction...
June 9, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29881666/nicu-hospitalization-long-term-implications-on-parenting-and-child-behaviors
#17
Rachel E Lean, Cynthia E Rogers, Rachel A Paul, Emily D Gerstein
Purpose of review: Parents of infants admitted to the Neonatal Intensive Care Unit (NICU) experience psychological distress, loss of the parenting role, and disruptions to parent-infant bonding. The inclusion of evidence-based practices to address these challenges in the NICU has largely been based upon short-term improvements in parent and infant functioning. However, less is known regarding the extent to which family-based interventions may also be associated with longer-term parenting behaviors and children's neurobehavioral outcomes...
March 2018: Current Treatment Options in Pediatrics
https://www.readbyqxmd.com/read/29852413/diagnostic-yield-of-targeted-massively-parallel-sequencing-in-children-with-epileptic-encephalopathy
#18
Kavitha Kothur, Katherine Holman, Elizabeth Farnsworth, Gladys Ho, Michelle Lorentzos, Christopher Troedson, Sachin Gupta, Richard Webster, Peter G Procopis, Manoj P Menezes, Jayne Antony, Simone Ardern-Holmes, Russell C Dale, John Christodoulou, Deepak Gill, Bruce Bennetts
PURPOSE: To report our institutional experience of targeted massively parallel sequencing (MPS) testing in children with epilepsy. METHOD: We retrospectively analysed the yield of targeted epileptic encephalopathy (EE) panel of 71 known EE genes in patients with epilepsy of unknown cause, who underwent clinical triage by a group of neurologists prior to the testing. We compared cost of the EE panel approach compared to traditional evaluation in patients with identified pathogenic variants...
July 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29843273/post-discharge-outcomes-of-failed-car-seat-tolerance-screens-a-case-control-and-follow-up-study
#19
P Sharma, N L Davis
BACKGROUND: Despite widespread implementation, limited data exists relating morbidity or adverse outcomes to Car Seat Tolerance Screen (CSTS) result in preterm and low birth weight (LBW) neonates. The objective of this study was to determine longer term post-discharge outcomes of infants who failed a CSTS. METHODS: We performed a case control study evaluating outcomes of infants born over one year who failed vs. passed an initial CSTS, utilizing both retrospective medical record review and parental survey data 2- 3 years after discharge...
May 23, 2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29791872/gene-expression-in-cord-blood-links-genetic-risk-for-neurodevelopmental-disorders-with-maternal-psychological-distress-and-adverse-childhood-outcomes
#20
Michael S Breen, Aliza P Wingo, Nastassja Koen, Kirsten A Donald, Mark Nicol, Heather J Zar, Kerry J Ressler, Joseph D Buxbaum, Dan J Stein
Prenatal exposure to maternal stress and depression has been identified as a risk factor for adverse behavioral and neurodevelopmental outcomes in early childhood. However, the molecular mechanisms through which maternal psychopathology shapes offspring development remain poorly understood. We applied transcriptome-wide screens to 149 umbilical cord blood samples from neonates born to mothers with posttraumatic stress disorder (PTSD; n = 20), depression (n = 31) and PTSD with comorbid depression (n = 13), compared to carefully matched trauma exposed controls (n = 23) and healthy mothers (n = 62)...
May 20, 2018: Brain, Behavior, and Immunity
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