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https://www.readbyqxmd.com/read/28323192/multimodality-management-of-spetzler-martin-grade-3-brain-arteriovenous-malformations-with-subgroup-analysis
#1
Isaac Josh Abecassis, John D Nerva, Abdullah Feroze, Jason Barber, Basavaraj V Ghodke, Louis J Kim, Laligam N Sekhar
INTRODUCTION: Spetzler-Martin grade 3 (SM3) lesions entail 4 distinct subtypes described based on size, eloquence, and deep venous drainage (DVD) (3A-3D). The ideal management of each is contentious, and the results of A Randomized Trial of Unruptured Brain AVMs (ARUBA) introduced additional controversy and attention towards management strategies of unruptured bAVMs. METHODS: We retrospectively reviewed 114 patients with treated SM3 bAVMs, including both ruptured and unruptured lesions...
March 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28301859/brief-telephone-delivered-cognitive-behavioral-therapy-targeted-to-parents-of-children-with-functional-abdominal-pain-a-randomized-controlled-trial
#2
Rona L Levy, Shelby L Langer, Miranda A L van Tilburg, Joan M Romano, Tasha B Murphy, Lynn S Walker, Lloyd A Mancl, Robyn L Claar, Melissa M DuPen, William E Whitehead, Bisher Abdullah, Kimberly S Swanson, Melissa D Baker, Susan A Stoner, Dennis L Christie, Andrew D Feld
Pediatric functional abdominal pain disorders (FAPDs) are associated with increased health care utilization, school absences, and poor quality of life (QoL). Cost-effective and accessible interventions are needed. This multisite study tested the effects of a 3-session cognitive behavioral intervention delivered to parents, in-person or remotely, on the primary outcome of pain severity and secondary outcomes (process measures) of parental solicitousness, pain beliefs, catastrophizing, and child-reported coping...
April 2017: Pain
https://www.readbyqxmd.com/read/28298418/disrupting-the-cd47-sirp%C3%AE-anti-phagocytic-axis-by-a-humanized-anti-cd47-antibody-is-an-efficacious-treatment-for-malignant-pediatric-brain-tumors
#3
Sharareh Gholamin, Siddhartha S Mitra, Abdullah H Feroze, Jie Liu, Suzana A Kahn, Michael Zhang, Rogelio Esparza, Chase Richard, Vijay Ramaswamy, Marc Remke, Anne K Volkmer, Stephen Willingham, Anitha Ponnuswami, Aaron McCarty, Patricia Lovelace, Theresa A Storm, Simone Schubert, Gregor Hutter, Cyndhavi Narayanan, Pauline Chu, Eric H Raabe, Griffith Harsh, Michael D Taylor, Michelle Monje, Yoon-Jae Cho, Ravi Majeti, Jens P Volkmer, Paul G Fisher, Gerald Grant, Gary K Steinberg, Hannes Vogel, Michael Edwards, Irving L Weissman, Samuel H Cheshier
Morbidity and mortality associated with pediatric malignant primary brain tumors remain high in the absence of effective therapies. Macrophage-mediated phagocytosis of tumor cells via blockade of the anti-phagocytic CD47-SIRPα interaction using anti-CD47 antibodies has shown promise in preclinical xenografts of various human malignancies. We demonstrate the effect of a humanized anti-CD47 antibody, Hu5F9-G4, on five aggressive and etiologically distinct pediatric brain tumors: group 3 medulloblastoma (primary and metastatic), atypical teratoid rhabdoid tumor, primitive neuroectodermal tumor, pediatric glioblastoma, and diffuse intrinsic pontine glioma...
March 15, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28292943/molecular-details-underlying-dynamic-structures-and-regulation-of-the-human-26s-proteasome
#4
Xiaorong Wang, Peter Cimermancic, Clinton Yu, Andreas Schweitzer, Nikita Chopra, James L Engel, Charles H Greenberg, Alexander S Huszagh, Florian Beck, Eri Sakata, Yingying Yang, Eric J Novitsky, Alexander Leitner, Paolo Nanni, Abdullah Kahraman, Xing Guo, Jack E Dixon, Scott D Rychnovsky, Ruedi Aebersold, Wolfgang Baumeister, Andrej Sali, Lan Huang
The 26S proteasome is the macromolecular machine responsible for ATP/ubiquitin dependent degradation. As aberration in proteasomal degradation has been implicated in many human diseases, structural analysis of the human 26S proteasome complex is essential to advance our understanding of its action and regulation mechanisms. In recent years, cross-linking mass spectrometry (XL-MS) has emerged as a powerful tool for elucidating structural topologies of large protein assemblies, with its unique capability of studying protein complexes in cells...
March 14, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/28283372/influenza-vaccine-uptake-determinants-motivators-and-barriers-of-the-vaccine-receipt-among-healthcare-workers-in-a-tertiary-care-hospital-in-saudi-arabia
#5
H K Haridi, K A Salman, E A Basaif, D K Al-Skaibi
BACKGROUND: Influenza vaccination of healthcare workers (HCWs) is essential for patient safety, their own safety, and hospital operation. However, despite its strong recommendation, studies indicates a low rate of vaccine uptake. AIM: To assess rates of, and factors affecting, influenza vaccine uptake among HCWs. METHODS: A cross-sectional survey was carried out during October 1(st) to 16(th), 2015, among HCWs in King Abdullah Medical City in Makkah, Saudi Arabia...
February 9, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28280790/environmental-assessment-of-al-hammar-marsh-southern-iraq
#6
Hind Fadhil Abdullah Al-Gburi, Balsam Salim Al-Tawash, Hadi Salim Al-Lafta
AIM: (a) To determine the spatial distributions and levels of major and minor elements, as well as heavy metals, in water, sediment, and biota (plant and fish) in Al-Hammar Marsh, southern Iraq, and ultimately to supply more comprehensive information for policy-makers to manage the contaminants input into the marsh so that their concentrations do not reach toxic levels. (b) to characterize the seasonal changes in the marsh surface water quality. (c) to address the potential environmental risk of these elements by comparison with the historical levels and global quality guidelines (i...
February 2017: Heliyon
https://www.readbyqxmd.com/read/28274898/association-of-benign-paroxysmal-positional-vertigo-with-osteoporosis-and-vitamin-d-deficiency-a-case-controlled-study
#7
Abdullah Karataş, Gülşah Acar Yüceant, Turgut Yüce, Cemal Hacı, Işıl Taylan Cebi, Mehti Salviz
OBJECTIVE: Benign paroxysmal positional vertigo (BPPV) is a common type of vertigo caused by the peripheral vestibular system. The majority of cases are accepted as idiopathic. Calcium metabolism also plays a primary role in the synthesis/absorption of otoconia made of calcium carbonate and thus might be an etiological factor in the onset of BPPV. In this study, we aimed to investigate the role of osteoporosis and vitamin D in the etiology of BPPV by comparing BPPV patients with hospital-based controls...
March 9, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28273802/the%C3%A2-prevalence%C3%A2-of%C3%A2-micronutrient%C3%A2-deficiencies%C3%A2-and%C3%A2-inadequacies%C3%A2-in%C3%A2-the%C3%A2-middle%C3%A2-east%C3%A2-and%C3%A2-approaches%C3%A2-to%C3%A2-interventions
#8
REVIEW
Nahla Hwalla, Ayesha Salem Al Dhaheri, Hadia Radwan, Hanan Abdullah Alfawaz, Mona A Fouda, Nasser Mohammed Al-Daghri, Sahar Zaghloul, Jeffrey B Blumberg
Micronutrient deficiencies and inadequacies constitute a global health issue, particularly among countries in the Middle East. The objective of this review is to identify micronutrient deficits in the Middle East and to consider current and new approaches to address this problem. Based on the availability of more recent data, this review is primarily focused on countries that are in advanced nutrition transition. Prominent deficits in folate, iron, and vitamin D are noted among children/adolescents, women of childbearing age, pregnant women, and the elderly...
March 3, 2017: Nutrients
https://www.readbyqxmd.com/read/28260978/measurements-of-the-formula-see-text-production-cross-section-in-lepton-jets-final-states-in-pp-collisions-at-8-formula-see-text-and-ratio-of-8-to-7%C3%A2-formula-see-text-cross-sections
#9
V Khachatryan, A M Sirunyan, A Tumasyan, W Adam, E Asilar, T Bergauer, J Brandstetter, E Brondolin, M Dragicevic, J Erö, M Flechl, M Friedl, R Frühwirth, V M Ghete, C Hartl, N Hörmann, J Hrubec, M Jeitler, V Knünz, A König, M Krammer, I Krätschmer, D Liko, T Matsushita, I Mikulec, D Rabady, B Rahbaran, H Rohringer, J Schieck, R Schöfbeck, J Strauss, W Treberer-Treberspurg, W Waltenberger, C-E Wulz, V Mossolov, N Shumeiko, J Suarez Gonzalez, S Alderweireldt, T Cornelis, E A De Wolf, X Janssen, A Knutsson, J Lauwers, S Luyckx, M Van De Klundert, H Van Haevermaet, P Van Mechelen, N Van Remortel, A Van Spilbeeck, S Abu Zeid, F Blekman, J D'Hondt, N Daci, I De Bruyn, K Deroover, N Heracleous, J Keaveney, S Lowette, M Maes, L Moreels, A Olbrechts, Q Python, D Strom, S Tavernier, W Van Doninck, P Van Mulders, G P Van Onsem, I Van Parijs, P Barria, H Brun, C Caillol, B Clerbaux, G De Lentdecker, G Fasanella, L Favart, A Grebenyuk, G Karapostoli, T Lenzi, A Léonard, T Maerschalk, A Marinov, L Perniè, A Randle-Conde, T Reis, T Seva, C Vander Velde, P Vanlaer, R Yonamine, F Zenoni, F Zhang, K Beernaert, L Benucci, A Cimmino, S Costantini, S Crucy, D Dobur, A Fagot, G Garcia, M Gul, J Mccartin, A A Ocampo Rios, D Poyraz, D Ryckbosch, S Salva, M Sigamani, N Strobbe, M Tytgat, W Van Driessche, E Yazgan, N Zaganidis, S Basegmez, C Beluffi, O Bondu, S Brochet, G Bruno, A Caudron, L Ceard, G G Da Silveira, C Delaere, D Favart, L Forthomme, A Giammanco, J Hollar, A Jafari, P Jez, M Komm, V Lemaitre, A Mertens, M Musich, C Nuttens, L Perrini, A Pin, K Piotrzkowski, A Popov, L Quertenmont, M Selvaggi, M Vidal Marono, N Beliy, G H Hammad, W L Aldá Júnior, F L Alves, G A Alves, L Brito, M Correa Martins Junior, M Hamer, C Hensel, C Mora Herrera, A Moraes, M E Pol, P Rebello Teles, E Belchior Batista Das Chagas, W Carvalho, J Chinellato, A Custódio, E M Da Costa, D De Jesus Damiao, C De Oliveira Martins, S Fonseca De Souza, L M Huertas Guativa, H Malbouisson, D Matos Figueiredo, L Mundim, H Nogima, W L Prado Da Silva, A Santoro, A Sznajder, E J Tonelli Manganote, A Vilela Pereira, S Ahuja, C A Bernardes, A De Souza Santos, S Dogra, T R Fernandez Perez Tomei, E M Gregores, P G Mercadante, C S Moon, S F Novaes, Sandra S Padula, D Romero Abad, J C Ruiz Vargas, A Aleksandrov, R Hadjiiska, P Iaydjiev, M Rodozov, S Stoykova, G Sultanov, M Vutova, A Dimitrov, I Glushkov, L Litov, B Pavlov, P Petkov, M Ahmad, J G Bian, G M Chen, H S Chen, M Chen, T Cheng, R Du, C H Jiang, R Plestina, F Romeo, S M Shaheen, A Spiezia, J Tao, C Wang, Z Wang, H Zhang, C Asawatangtrakuldee, Y Ban, Q Li, S Liu, Y Mao, S J Qian, D Wang, Z Xu, C Avila, A Cabrera, L F Chaparro Sierra, C Florez, J P Gomez, B Gomez Moreno, J C Sanabria, N Godinovic, D Lelas, I Puljak, P M Ribeiro Cipriano, Z Antunovic, M Kovac, V Brigljevic, K Kadija, J Luetic, S Micanovic, L Sudic, A Attikis, G Mavromanolakis, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, M Bodlak, M Finger, M Finger, A A Abdelalim, A Awad, M El Sawy, A Mahrous, A Radi, B Calpas, M Kadastik, M Murumaa, M Raidal, A Tiko, C Veelken, P Eerola, J Pekkanen, M Voutilainen, J Härkönen, V Karimäki, R Kinnunen, T Lampén, K Lassila-Perini, S Lehti, T Lindén, P Luukka, T Mäenpää, T Peltola, E Tuominen, J Tuominiemi, E Tuovinen, L Wendland, J Talvitie, T Tuuva, M Besancon, F Couderc, M Dejardin, D Denegri, B Fabbro, J L Faure, C Favaro, F Ferri, S Ganjour, A Givernaud, P Gras, G Hamel de Monchenault, P Jarry, E Locci, M Machet, J Malcles, J Rander, A Rosowsky, M Titov, A Zghiche, I Antropov, S Baffioni, F Beaudette, P Busson, L Cadamuro, E Chapon, C Charlot, T Dahms, O Davignon, N Filipovic, A Florent, R Granier de Cassagnac, S Lisniak, L Mastrolorenzo, P Miné, I N Naranjo, M Nguyen, C Ochando, G Ortona, P Paganini, P Pigard, S Regnard, R Salerno, J B Sauvan, Y Sirois, T Strebler, Y Yilmaz, A Zabi, J-L Agram, J Andrea, A Aubin, D Bloch, J-M Brom, M Buttignol, E C Chabert, N Chanon, C Collard, E Conte, X Coubez, J-C Fontaine, D Gelé, U Goerlach, C Goetzmann, A-C Le Bihan, J A Merlin, K Skovpen, P Van Hove, S Gadrat, S Beauceron, C Bernet, G Boudoul, E Bouvier, C A Carrillo Montoya, R Chierici, D Contardo, B Courbon, P Depasse, H El Mamouni, J Fan, J Fay, S Gascon, M Gouzevitch, B Ille, F Lagarde, I B Laktineh, M Lethuillier, L Mirabito, A L Pequegnot, S Perries, J D Ruiz Alvarez, D Sabes, L Sgandurra, V Sordini, M Vander Donckt, P Verdier, S Viret, T Toriashvili, Z Tsamalaidze, C Autermann, S Beranek, M Edelhoff, L Feld, A Heister, M K Kiesel, K Klein, M Lipinski, A Ostapchuk, M Preuten, F Raupach, S Schael, J F Schulte, T Verlage, H Weber, B Wittmer, V Zhukov, M Ata, M Brodski, E Dietz-Laursonn, D Duchardt, M Endres, M Erdmann, S Erdweg, T Esch, R Fischer, A Güth, T Hebbeker, C Heidemann, K Hoepfner, D Klingebiel, S Knutzen, P Kreuzer, M Merschmeyer, A Meyer, P Millet, M Olschewski, K Padeken, P Papacz, T Pook, M Radziej, H Reithler, M Rieger, F Scheuch, L Sonnenschein, D Teyssier, S Thüer, V Cherepanov, Y Erdogan, G Flügge, H Geenen, M Geisler, F Hoehle, B Kargoll, T Kress, Y Kuessel, A Künsken, J Lingemann, A Nehrkorn, A Nowack, I M Nugent, C Pistone, O Pooth, A Stahl, M Aldaya Martin, I Asin, N Bartosik, O Behnke, U Behrens, A J Bell, K Borras, A Burgmeier, A Campbell, S Choudhury, F Costanza, C Diez Pardos, G Dolinska, S Dooling, T Dorland, G Eckerlin, D Eckstein, T Eichhorn, G Flucke, E Gallo, J Garay Garcia, A Geiser, A Gizhko, P Gunnellini, J Hauk, M Hempel, H Jung, A Kalogeropoulos, O Karacheban, M Kasemann, P Katsas, J Kieseler, C Kleinwort, I Korol, W Lange, J Leonard, K Lipka, A Lobanov, W Lohmann, R Mankel, I Marfin, I-A Melzer-Pellmann, A B Meyer, G Mittag, J Mnich, A Mussgiller, S Naumann-Emme, A Nayak, E Ntomari, H Perrey, D Pitzl, R Placakyte, A Raspereza, B Roland, M Ö Sahin, P Saxena, T Schoerner-Sadenius, M Schröder, C Seitz, S Spannagel, K D Trippkewitz, R Walsh, C Wissing, V Blobel, M Centis Vignali, A R Draeger, J Erfle, E Garutti, K Goebel, D Gonzalez, M Görner, J Haller, M Hoffmann, R S Höing, A Junkes, R Klanner, R Kogler, N Kovalchuk, T Lapsien, T Lenz, I Marchesini, D Marconi, M Meyer, D Nowatschin, J Ott, F Pantaleo, T Peiffer, A Perieanu, N Pietsch, J Poehlsen, D Rathjens, C Sander, C Scharf, H Schettler, P Schleper, E Schlieckau, A Schmidt, J Schwandt, V Sola, H Stadie, G Steinbrück, H Tholen, D Troendle, E Usai, L Vanelderen, A Vanhoefer, B Vormwald, M Akbiyik, C Barth, C Baus, J Berger, C Böser, E Butz, T Chwalek, F Colombo, W De Boer, A Descroix, A Dierlamm, S Fink, F Frensch, R Friese, M Giffels, A Gilbert, D Haitz, F Hartmann, S M Heindl, U Husemann, I Katkov, A Kornmayer, P Lobelle Pardo, B Maier, H Mildner, M U Mozer, T Müller, Th Müller, M Plagge, G Quast, K Rabbertz, S Röcker, F Roscher, G Sieber, H J Simonis, F M Stober, R Ulrich, J Wagner-Kuhr, S Wayand, M Weber, T Weiler, C Wöhrmann, R Wolf, G Anagnostou, G Daskalakis, T Geralis, V A Giakoumopoulou, A Kyriakis, D Loukas, A Psallidas, I Topsis-Giotis, A Agapitos, S Kesisoglou, A Panagiotou, N Saoulidou, E Tziaferi, I Evangelou, G Flouris, C Foudas, P Kokkas, N Loukas, N Manthos, I Papadopoulos, E Paradas, J Strologas, G Bencze, C Hajdu, A Hazi, P Hidas, D Horvath, F Sikler, V Veszpremi, G Vesztergombi, A J Zsigmond, N Beni, S Czellar, J Karancsi, J Molnar, Z Szillasi, M Bartók, A Makovec, P Raics, Z L Trocsanyi, B Ujvari, P Mal, K Mandal, D K Sahoo, N Sahoo, S K Swain, S Bansal, S B Beri, V Bhatnagar, R Chawla, R Gupta, U Bhawandeep, A K Kalsi, A Kaur, M Kaur, R Kumar, A Mehta, M Mittal, J B Singh, G Walia, Ashok Kumar, A Bhardwaj, B C Choudhary, R B Garg, A Kumar, S Malhotra, M Naimuddin, N Nishu, K Ranjan, R Sharma, V Sharma, S Bhattacharya, K Chatterjee, S Dey, S Dutta, Sa Jain, N Majumdar, A Modak, K Mondal, S Mukherjee, S Mukhopadhyay, A Roy, D Roy, S Roy Chowdhury, S Sarkar, M Sharan, A Abdulsalam, R Chudasama, D Dutta, V Jha, V Kumar, A K Mohanty, L M Pant, P Shukla, A Topkar, T Aziz, S Banerjee, S Bhowmik, R M Chatterjee, R K Dewanjee, S Dugad, S Ganguly, S Ghosh, M Guchait, A Gurtu, G Kole, S Kumar, B Mahakud, M Maity, G Majumder, K Mazumdar, S Mitra, G B Mohanty, B Parida, T Sarkar, N Sur, B Sutar, N Wickramage, S Chauhan, S Dube, K Kothekar, S Sharma, H Bakhshiansohi, H Behnamian, S M Etesami, A Fahim, R Goldouzian, M Khakzad, M Mohammadi Najafabadi, M Naseri, S Paktinat Mehdiabadi, F Rezaei Hosseinabadi, B Safarzadeh, M Zeinali, M Felcini, M Grunewald, M Abbrescia, C Calabria, C Caputo, A Colaleo, D Creanza, L Cristella, N De Filippis, M De Palma, L Fiore, G Iaselli, G Maggi, M Maggi, G Miniello, S My, S Nuzzo, A Pompili, G Pugliese, R Radogna, A Ranieri, G Selvaggi, L Silvestris, R Venditti, P Verwilligen, G Abbiendi, C Battilana, A C Benvenuti, D Bonacorsi, S Braibant-Giacomelli, L Brigliadori, R Campanini, P Capiluppi, A Castro, F R Cavallo, S S Chhibra, G Codispoti, M Cuffiani, G M Dallavalle, F Fabbri, A Fanfani, D Fasanella, P Giacomelli, C Grandi, L Guiducci, S Marcellini, G Masetti, A Montanari, F L Navarria, A Perrotta, A M Rossi, T Rovelli, G P Siroli, N Tosi, R Travaglini, G Cappello, M Chiorboli, S Costa, A Di Mattia, F Giordano, R Potenza, A Tricomi, C Tuve, G Barbagli, V Ciulli, C Civinini, R D'Alessandro, E Focardi, S Gonzi, V Gori, P Lenzi, M Meschini, S Paoletti, G Sguazzoni, A Tropiano, L Viliani, L Benussi, S Bianco, F Fabbri, D Piccolo, F Primavera, V Calvelli, F Ferro, M Lo Vetere, M R Monge, E Robutti, S Tosi, L Brianza, M E Dinardo, S Fiorendi, S Gennai, R Gerosa, A Ghezzi, P Govoni, S Malvezzi, R A Manzoni, B Marzocchi, D Menasce, L Moroni, M Paganoni, D Pedrini, S Ragazzi, N Redaelli, T Tabarelli de Fatis, S Buontempo, N Cavallo, S Di Guida, M Esposito, F Fabozzi, A O M Iorio, G Lanza, L Lista, S Meola, M Merola, P Paolucci, C Sciacca, F Thyssen, P Azzi, N Bacchetta, L Benato, D Bisello, A Boletti, A Branca, R Carlin, P Checchia, M Dall'Osso, T Dorigo, U Dosselli, F Gasparini, U Gasparini, A Gozzelino, K Kanishchev, S Lacaprara, M Margoni, A T Meneguzzo, J Pazzini, N Pozzobon, P Ronchese, F Simonetto, E Torassa, M Tosi, S Ventura, M Zanetti, P Zotto, A Zucchetta, G Zumerle, A Braghieri, A Magnani, P Montagna, S P Ratti, V Re, C Riccardi, P Salvini, I Vai, P Vitulo, L Alunni Solestizi, M Biasini, G M Bilei, D Ciangottini, L Fanò, P Lariccia, G Mantovani, M Menichelli, A Saha, A Santocchia, K Androsov, P Azzurri, G Bagliesi, J Bernardini, T Boccali, R Castaldi, M A Ciocci, R Dell'Orso, S Donato, G Fedi, L Foà, A Giassi, M T Grippo, F Ligabue, T Lomtadze, L Martini, A Messineo, F Palla, A Rizzi, A Savoy-Navarro, A T Serban, P Spagnolo, R Tenchini, G Tonelli, A Venturi, P G Verdini, L Barone, F Cavallari, G D'imperio, D Del Re, M Diemoz, S Gelli, C Jorda, E Longo, F Margaroli, P Meridiani, G Organtini, R Paramatti, F Preiato, S Rahatlou, C Rovelli, F Santanastasio, P Traczyk, N Amapane, R Arcidiacono, S Argiro, M Arneodo, R Bellan, C Biino, N Cartiglia, M Costa, R Covarelli, A Degano, N Demaria, L Finco, B Kiani, C Mariotti, S Maselli, E Migliore, V Monaco, E Monteil, M M Obertino, L Pacher, N Pastrone, M Pelliccioni, G L Pinna Angioni, F Ravera, A Romero, M Ruspa, R Sacchi, A Solano, A Staiano, U Tamponi, S Belforte, V Candelise, M Casarsa, F Cossutti, G Della Ricca, B Gobbo, C La Licata, M Marone, A Schizzi, A Zanetti, A Kropivnitskaya, S K Nam, D H Kim, G N Kim, M S Kim, D J Kong, S Lee, Y D Oh, A Sakharov, D C Son, J A Brochero Cifuentes, H Kim, T J Kim, S Song, S Choi, Y Go, D Gyun, B Hong, M Jo, H Kim, Y Kim, B Lee, K Lee, K S Lee, S Lee, S K Park, Y Roh, H D Yoo, M Choi, H Kim, J H Kim, J S H Lee, I C Park, G Ryu, M S Ryu, Y Choi, J Goh, D Kim, E Kwon, J Lee, I Yu, V Dudenas, A Juodagalvis, J Vaitkus, I Ahmed, Z A Ibrahim, J R Komaragiri, M A B Md Ali, F Mohamad Idris, W A T Wan Abdullah, M N Yusli, E Casimiro Linares, H Castilla-Valdez, E De La Cruz-Burelo, I Heredia-De La Cruz, A Hernandez-Almada, R Lopez-Fernandez, A Sanchez-Hernandez, S Carrillo Moreno, F Vazquez Valencia, I Pedraza, H A Salazar Ibarguen, A Morelos Pineda, D Krofcheck, P H Butler, A Ahmad, M Ahmad, Q Hassan, H R Hoorani, W A Khan, T Khurshid, M Shoaib, H Bialkowska, M Bluj, B Boimska, T Frueboes, M Górski, M Kazana, K Nawrocki, K Romanowska-Rybinska, M Szleper, P Zalewski, G Brona, K Bunkowski, A Byszuk, K Doroba, A Kalinowski, M Konecki, J Krolikowski, M Misiura, M Olszewski, M Walczak, P Bargassa, C Beirão Da Cruz E Silva, A Di Francesco, P Faccioli, P G Ferreira Parracho, M Gallinaro, N Leonardo, L Lloret Iglesias, F Nguyen, J Rodrigues Antunes, J Seixas, O Toldaiev, D Vadruccio, J Varela, P Vischia, S Afanasiev, P Bunin, M Gavrilenko, I Golutvin, I Gorbunov, A Kamenev, V Karjavin, V Konoplyanikov, A Lanev, A Malakhov, V Matveev, P Moisenz, V Palichik, V Perelygin, S Shmatov, S Shulha, N Skatchkov, V Smirnov, A Zarubin, V Golovtsov, Y Ivanov, V Kim, E Kuznetsova, P Levchenko, V Murzin, V Oreshkin, I Smirnov, V Sulimov, L Uvarov, S Vavilov, A Vorobyev, Yu Andreev, A Dermenev, S Gninenko, N Golubev, A Karneyeu, M Kirsanov, N Krasnikov, A Pashenkov, D Tlisov, A Toropin, V Epshteyn, V Gavrilov, N Lychkovskaya, V Popov, I Pozdnyakov, G Safronov, A Spiridonov, E Vlasov, A Zhokin, A Bylinkin, V Andreev, M Azarkin, I Dremin, M Kirakosyan, A Leonidov, G Mesyats, S V Rusakov, A Baskakov, A Belyaev, E Boos, V Bunichev, M Dubinin, L Dudko, A Ershov, A Gribushin, V Klyukhin, N Korneeva, I Lokhtin, I Myagkov, S Obraztsov, M Perfilov, V Savrin, I Azhgirey, I Bayshev, S Bitioukov, V Kachanov, A Kalinin, D Konstantinov, V Krychkine, V Petrov, R Ryutin, A Sobol, L Tourtchanovitch, S Troshin, N Tyurin, A Uzunian, A Volkov, P Adzic, J Milosevic, V Rekovic, J Alcaraz Maestre, E Calvo, M Cerrada, M Chamizo Llatas, N Colino, B De La Cruz, A Delgado Peris, D Domínguez Vázquez, A Escalante Del Valle, C Fernandez Bedoya, J P Fernández Ramos, J Flix, M C Fouz, P Garcia-Abia, O Gonzalez Lopez, S Goy Lopez, J M Hernandez, M I Josa, E Navarro De Martino, A Pérez-Calero Yzquierdo, J Puerta Pelayo, A Quintario Olmeda, I Redondo, L Romero, J Santaolalla, M S Soares, C Albajar, J F de Trocóniz, M Missiroli, D Moran, J Cuevas, J Fernandez Menendez, S Folgueras, I Gonzalez Caballero, E Palencia Cortezon, J M Vizan Garcia, I J Cabrillo, A Calderon, J R Castiñeiras De Saa, P De Castro Manzano, J Duarte Campderros, M Fernandez, J Garcia-Ferrero, G Gomez, A Lopez Virto, J Marco, R Marco, C Martinez Rivero, F Matorras, F J Munoz Sanchez, J Piedra Gomez, T Rodrigo, A Y Rodríguez-Marrero, A Ruiz-Jimeno, L Scodellaro, N Trevisani, I Vila, R Vilar Cortabitarte, D Abbaneo, E Auffray, G Auzinger, M Bachtis, P Baillon, A H Ball, D Barney, A Benaglia, J Bendavid, L Benhabib, J F Benitez, G M Berruti, P Bloch, A Bocci, A Bonato, C Botta, H Breuker, T Camporesi, R Castello, G Cerminara, M D'Alfonso, D d'Enterria, A Dabrowski, V Daponte, A David, M De Gruttola, F De Guio, A De Roeck, S De Visscher, E Di Marco, M Dobson, M Dordevic, B Dorney, T du Pree, M Dünser, N Dupont, A Elliott-Peisert, G Franzoni, W Funk, D Gigi, K Gill, D Giordano, M Girone, F Glege, R Guida, S Gundacker, M Guthoff, J Hammer, P Harris, J Hegeman, V Innocente, P Janot, H Kirschenmann, M J Kortelainen, K Kousouris, K Krajczar, P Lecoq, C Lourenço, M T Lucchini, N Magini, L Malgeri, M Mannelli, A Martelli, L Masetti, F Meijers, S Mersi, E Meschi, F Moortgat, S Morovic, M Mulders, M V Nemallapudi, H Neugebauer, S Orfanelli, L Orsini, L Pape, E Perez, M Peruzzi, A Petrilli, G Petrucciani, A Pfeiffer, D Piparo, A Racz, G Rolandi, M Rovere, M Ruan, H Sakulin, C Schäfer, C Schwick, M Seidel, A Sharma, P Silva, M Simon, P Sphicas, J Steggemann, B Stieger, M Stoye, Y Takahashi, D Treille, A Triossi, A Tsirou, G I Veres, N Wardle, H K Wöhri, A Zagozdzinska, W D Zeuner, W Bertl, K Deiters, W Erdmann, R Horisberger, Q Ingram, H C Kaestli, D Kotlinski, U Langenegger, D Renker, T Rohe, F Bachmair, L Bäni, L Bianchini, B Casal, G Dissertori, M Dittmar, M Donegà, P Eller, C Grab, C Heidegger, D Hits, J Hoss, G Kasieczka, W Lustermann, B Mangano, M Marionneau, P Martinez Ruiz Del Arbol, M Masciovecchio, D Meister, F Micheli, P Musella, F Nessi-Tedaldi, F Pandolfi, J Pata, F Pauss, L Perrozzi, M Quittnat, M Rossini, A Starodumov, M Takahashi, V R Tavolaro, K Theofilatos, R Wallny, T K Aarrestad, C Amsler, L Caminada, M F Canelli, V Chiochia, A De Cosa, C Galloni, A Hinzmann, T Hreus, B Kilminster, C Lange, J Ngadiuba, D Pinna, P Robmann, F J Ronga, D Salerno, Y Yang, M Cardaci, K H Chen, T H Doan, Sh Jain, R Khurana, M Konyushikhin, C M Kuo, W Lin, Y J Lu, S S Yu, Arun Kumar, R Bartek, P Chang, Y H Chang, Y W Chang, Y Chao, K F Chen, P H Chen, C Dietz, F Fiori, U Grundler, W-S Hou, Y Hsiung, Y F Liu, R-S Lu, M Miñano Moya, E Petrakou, J F Tsai, Y M Tzeng, B Asavapibhop, K Kovitanggoon, G Singh, N Srimanobhas, N Suwonjandee, A Adiguzel, S Cerci, Z S Demiroglu, C Dozen, I Dumanoglu, S Girgis, G Gokbulut, Y Guler, E Gurpinar, I Hos, E E Kangal, A Kayis Topaksu, G Onengut, K Ozdemir, S Ozturk, B Tali, H Topakli, M Vergili, C Zorbilmez, I V Akin, B Bilin, S Bilmis, B Isildak, G Karapinar, M Yalvac, M Zeyrek, E Gülmez, M Kaya, O Kaya, E A Yetkin, T Yetkin, A Cakir, K Cankocak, S Sen, F I Vardarlı, B Grynyov, L Levchuk, P Sorokin, R Aggleton, F Ball, L Beck, J J Brooke, E Clement, D Cussans, H Flacher, J Goldstein, M Grimes, G P Heath, H F Heath, J Jacob, L Kreczko, C Lucas, Z Meng, D M Newbold, S Paramesvaran, A Poll, T Sakuma, S Seif El Nasr-Storey, S Senkin, D Smith, V J Smith, K W Bell, A Belyaev, C Brew, R M Brown, L Calligaris, D Cieri, D J A Cockerill, J A Coughlan, K Harder, S Harper, E Olaiya, D Petyt, C H Shepherd-Themistocleous, A Thea, I R Tomalin, T Williams, W J Womersley, S D Worm, M Baber, R Bainbridge, O Buchmuller, A Bundock, D Burton, S Casasso, M Citron, D Colling, L Corpe, N Cripps, P Dauncey, G Davies, A De Wit, M Della Negra, P Dunne, A Elwood, W Ferguson, J Fulcher, D Futyan, G Hall, G Iles, M Kenzie, R Lane, R Lucas, L Lyons, A-M Magnan, S Malik, J Nash, A Nikitenko, J Pela, M Pesaresi, K Petridis, D M Raymond, A Richards, A Rose, C Seez, A Tapper, K Uchida, M Vazquez Acosta, T Virdee, S C Zenz, J E Cole, P R Hobson, A Khan, P Kyberd, D Leggat, D Leslie, I D Reid, P Symonds, L Teodorescu, M Turner, A Borzou, K Call, J Dittmann, K Hatakeyama, H Liu, N Pastika, O Charaf, S I Cooper, C Henderson, P Rumerio, D Arcaro, A Avetisyan, T Bose, C Fantasia, D Gastler, P Lawson, D Rankin, C Richardson, J Rohlf, J St John, L Sulak, D Zou, J Alimena, E Berry, S Bhattacharya, D Cutts, N Dhingra, A Ferapontov, A Garabedian, J Hakala, U Heintz, E Laird, G Landsberg, Z Mao, M Narain, S Piperov, S Sagir, R Syarif, R Breedon, G Breto, M Calderon De La Barca Sanchez, S Chauhan, M Chertok, J Conway, R Conway, P T Cox, R Erbacher, M Gardner, W Ko, R Lander, M Mulhearn, D Pellett, J Pilot, F Ricci-Tam, S Shalhout, J Smith, M Squires, D Stolp, M Tripathi, S Wilbur, R Yohay, R Cousins, P Everaerts, C Farrell, J Hauser, M Ignatenko, D Saltzberg, E Takasugi, V Valuev, M Weber, K Burt, R Clare, J Ellison, J W Gary, G Hanson, J Heilman, M Ivova Paneva, P Jandir, E Kennedy, F Lacroix, O R Long, A Luthra, M Malberti, M Olmedo Negrete, A Shrinivas, H Wei, S Wimpenny, B R Yates, J G Branson, G B Cerati, S Cittolin, R T D'Agnolo, M Derdzinski, A Holzner, R Kelley, D Klein, J Letts, I Macneill, D Olivito, S Padhi, M Pieri, M Sani, V Sharma, S Simon, M Tadel, A Vartak, S Wasserbaech, C Welke, F Würthwein, A Yagil, G Zevi Della Porta, J Bradmiller-Feld, C Campagnari, A Dishaw, V Dutta, K Flowers, M Franco Sevilla, P Geffert, C George, F Golf, L Gouskos, J Gran, J Incandela, N Mccoll, S D Mullin, J Richman, D Stuart, I Suarez, C West, J Yoo, D Anderson, A Apresyan, A Bornheim, J Bunn, Y Chen, J Duarte, A Mott, H B Newman, C Pena, M Pierini, M Spiropulu, J R Vlimant, S Xie, R Y Zhu, M B Andrews, V Azzolini, A Calamba, B Carlson, T Ferguson, M Paulini, J Russ, M Sun, H Vogel, I Vorobiev, J P Cumalat, W T Ford, A Gaz, F Jensen, A Johnson, M Krohn, T Mulholland, U Nauenberg, K Stenson, S R Wagner, J Alexander, A Chatterjee, J Chaves, J Chu, S Dittmer, N Eggert, N Mirman, G Nicolas Kaufman, J R Patterson, A Rinkevicius, A Ryd, L Skinnari, L Soffi, W Sun, S M Tan, W D Teo, J Thom, J Thompson, J Tucker, Y Weng, P Wittich, S Abdullin, M Albrow, J Anderson, G Apollinari, S Banerjee, L A T Bauerdick, A Beretvas, J Berryhill, P C Bhat, G Bolla, K Burkett, J N Butler, H W K Cheung, F Chlebana, S Cihangir, V D Elvira, I Fisk, J Freeman, E Gottschalk, L Gray, D Green, S Grünendahl, O Gutsche, J Hanlon, D Hare, R M Harris, S Hasegawa, J Hirschauer, Z Hu, B Jayatilaka, S Jindariani, M Johnson, U Joshi, A W Jung, B Klima, B Kreis, S Kwan, S Lammel, J Linacre, D Lincoln, R Lipton, T Liu, R Lopes De Sá, J Lykken, K Maeshima, J M Marraffino, V I Martinez Outschoorn, S Maruyama, D Mason, P McBride, P Merkel, K Mishra, S Mrenna, S Nahn, C Newman-Holmes, V O'Dell, K Pedro, O Prokofyev, G Rakness, E Sexton-Kennedy, A Soha, W J Spalding, L Spiegel, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, C Vernieri, M Verzocchi, R Vidal, H A Weber, A Whitbeck, F Yang, D Acosta, P Avery, P Bortignon, D Bourilkov, A Carnes, M Carver, D Curry, S Das, G P Di Giovanni, R D Field, I K Furic, S V Gleyzer, J Hugon, J Konigsberg, A Korytov, J F Low, P Ma, K Matchev, H Mei, P Milenovic, G Mitselmakher, D Rank, R Rossin, L Shchutska, M Snowball, D Sperka, N Terentyev, L Thomas, J Wang, S Wang, J Yelton, S Hewamanage, S Linn, P Markowitz, G Martinez, J L Rodriguez, A Ackert, J R Adams, T Adams, A Askew, J Bochenek, B Diamond, J Haas, S Hagopian, V Hagopian, K F Johnson, A Khatiwada, H Prosper, M Weinberg, M M Baarmand, V Bhopatkar, S Colafranceschi, M Hohlmann, H Kalakhety, D Noonan, T Roy, F Yumiceva, M R Adams, L Apanasevich, D Berry, R R Betts, I Bucinskaite, R Cavanaugh, O Evdokimov, L Gauthier, C E Gerber, D J Hofman, P Kurt, C O'Brien, I D Sandoval Gonzalez, C Silkworth, P Turner, N Varelas, Z Wu, M Zakaria, B Bilki, W Clarida, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, J-P Merlo, H Mermerkaya, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, K Yi, I Anderson, B A Barnett, B Blumenfeld, N Eminizer, D Fehling, L Feng, A V Gritsan, P Maksimovic, C Martin, M Osherson, J Roskes, A Sady, U Sarica, M Swartz, M Xiao, Y Xin, C You, P Baringer, A Bean, G Benelli, C Bruner, R P Kenny, D Majumder, M Malek, M Murray, S Sanders, R Stringer, Q Wang, A Ivanov, K Kaadze, S Khalil, M Makouski, Y Maravin, A Mohammadi, L K Saini, N Skhirtladze, S Toda, D Lange, F Rebassoo, D Wright, C Anelli, A Baden, O Baron, A Belloni, B Calvert, S C Eno, C Ferraioli, J A Gomez, N J Hadley, S Jabeen, R G Kellogg, T Kolberg, J Kunkle, Y Lu, A C Mignerey, Y H Shin, A Skuja, M B Tonjes, S C Tonwar, A Apyan, R Barbieri, A Baty, K Bierwagen, S Brandt, W Busza, I A Cali, Z Demiragli, L Di Matteo, G Gomez Ceballos, M Goncharov, D Gulhan, Y Iiyama, G M Innocenti, M Klute, D Kovalskyi, Y S Lai, Y-J Lee, A Levin, P D Luckey, A C Marini, C Mcginn, C Mironov, S Narayanan, X Niu, C Paus, D Ralph, C Roland, G Roland, J Salfeld-Nebgen, G S F Stephans, K Sumorok, M Varma, D Velicanu, J Veverka, J Wang, T W Wang, B Wyslouch, M Yang, V Zhukova, B Dahmes, A Evans, A Finkel, A Gude, P Hansen, S Kalafut, S C Kao, K Klapoetke, Y Kubota, Z Lesko, J Mans, S Nourbakhsh, N Ruckstuhl, R Rusack, N Tambe, J Turkewitz, J G Acosta, S Oliveros, E Avdeeva, K Bloom, S Bose, D R Claes, A Dominguez, C Fangmeier, R Gonzalez Suarez, R Kamalieddin, J Keller, D Knowlton, I Kravchenko, F Meier, J Monroy, F Ratnikov, J E Siado, G R Snow, M Alyari, J Dolen, J George, A Godshalk, C Harrington, I Iashvili, J Kaisen, A Kharchilava, A Kumar, S Rappoccio, B Roozbahani, G Alverson, E Barberis, D Baumgartel, M Chasco, A Hortiangtham, A Massironi, D M Morse, D Nash, T Orimoto, R Teixeira De Lima, D Trocino, R-J Wang, D Wood, J Zhang, K A Hahn, A Kubik, N Mucia, N Odell, B Pollack, A Pozdnyakov, M Schmitt, S Stoynev, K Sung, M Trovato, M Velasco, A Brinkerhoff, N Dev, M Hildreth, C Jessop, D J Karmgard, N Kellams, K Lannon, S Lynch, N Marinelli, F Meng, C Mueller, Y Musienko, T Pearson, M Planer, A Reinsvold, R Ruchti, G Smith, S Taroni, N Valls, M Wayne, M Wolf, A Woodard, L Antonelli, J Brinson, B Bylsma, L S Durkin, S Flowers, A Hart, C Hill, R Hughes, W Ji, K Kotov, T Y Ling, B Liu, W Luo, D Puigh, M Rodenburg, B L Winer, H W Wulsin, O Driga, P Elmer, J Hardenbrook, P Hebda, S A Koay, P Lujan, D Marlow, T Medvedeva, M Mooney, J Olsen, C Palmer, P Piroué, H Saka, D Stickland, C Tully, A Zuranski, S Malik, V E Barnes, D Benedetti, D Bortoletto, L Gutay, M K Jha, M Jones, K Jung, D H Miller, N Neumeister, B C Radburn-Smith, X Shi, I Shipsey, D Silvers, J Sun, A Svyatkovskiy, F Wang, W Xie, L Xu, N Parashar, J Stupak, A Adair, B Akgun, Z Chen, K M Ecklund, F J M Geurts, M Guilbaud, W Li, B Michlin, M Northup, B P Padley, R Redjimi, J Roberts, J Rorie, Z Tu, J Zabel, B Betchart, A Bodek, P de Barbaro, R Demina, Y Eshaq, T Ferbel, M Galanti, A Garcia-Bellido, J Han, A Harel, O Hindrichs, A Khukhunaishvili, G Petrillo, P Tan, M Verzetti, S Arora, A Barker, J P Chou, C Contreras-Campana, E Contreras-Campana, D Duggan, D Ferencek, Y Gershtein, R Gray, E Halkiadakis, D Hidas, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, A Lath, K Nash, S Panwalkar, M Park, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, M Foerster, G Riley, K Rose, S Spanier, A York, O Bouhali, A Castaneda Hernandez, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Kamon, V Krutelyov, R Mueller, I Osipenkov, Y Pakhotin, R Patel, A Perloff, A Rose, A Safonov, A Tatarinov, K A Ulmer, N Akchurin, C Cowden, J Damgov, C Dragoiu, P R Dudero, J Faulkner, S Kunori, K Lamichhane, S W Lee, T Libeiro, S Undleeb, I Volobouev, E Appelt, A G Delannoy, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, Y Mao, A Melo, H Ni, P Sheldon, B Snook, S Tuo, J Velkovska, Q Xu, M W Arenton, B Cox, B Francis, J Goodell, R Hirosky, A Ledovskoy, H Li, C Lin, C Neu, T Sinthuprasith, X Sun, Y Wang, E Wolfe, J Wood, F Xia, C Clarke, R Harr, P E Karchin, C Kottachchi Kankanamge Don, P Lamichhane, J Sturdy, D A Belknap, D Carlsmith, M Cepeda, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, R Hall-Wilton, M Herndon, A Hervé, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, A Mohapatra, I Ojalvo, T Perry, G A Pierro, G Polese, T Ruggles, T Sarangi, A Savin, A Sharma, N Smith, W H Smith, D Taylor, N Woods
A measurement of the top quark pair production ([Formula: see text]) cross section in proton-proton collisions at the centre-of-mass energy of 8[Formula: see text] is presented using data collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 19.6[Formula: see text]. This analysis is performed in the [Formula: see text] decay channels with one isolated, high transverse momentum electron or muon and at least four jets, at least one of which is required to be identified as originating from hadronization of a b quark...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28254344/concurrent-hydrogen-production-and-phosphorus-recovery-in-dual-chamber-microbial-electrolysis-cell
#10
Abdullah Almatouq, A O Babatunde
Concurrent hydrogen (H2) production and phosphorus (P) recovery were investigated in dual chamber microbial electrolysis cells (MECs). The aim of the study was to explore and understand the influence of applied voltage and influent COD concentration on concurrent H2 production and P recovery in MEC. P was efficiently precipitated at the cathode chamber and the precipitated crystals were verified as struvite, using X-ray diffraction and scanning electron microscopy analysis. The maximum P precipitation efficiency achieved by the MEC was 95%, and the maximum H2 production rate was 0...
February 15, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28250456/biallelic-mutations-in-human-dcc-cause-developmental-split-brain-syndrome
#11
Saumya S Jamuar, Klaus Schmitz-Abe, Alissa M D'Gama, Marie Drottar, Wai-Man Chan, Maya Peeva, Sarah Servattalab, Anh-Thu N Lam, Mauricio R Delgado, Nancy J Clegg, Zayed Al Zayed, Mohammad Asif Dogar, Ibrahim A Alorainy, Abdullah Abu Jamea, Khaled Abu-Amero, May Griebel, Wendy Ward, Ed S Lein, Kyriacos Markianos, A James Barkovich, Caroline D Robson, P Ellen Grant, Thomas M Bosley, Elizabeth C Engle, Christopher A Walsh, Timothy W Yu
Motor, sensory, and integrative activities of the brain are coordinated by a series of midline-bridging neuronal commissures whose development is tightly regulated. Here we report a new human syndrome in which these commissures are widely disrupted, thus causing clinical manifestations of horizontal gaze palsy, scoliosis, and intellectual disability. Affected individuals were found to possess biallelic loss-of-function mutations in the gene encoding the axon-guidance receptor 'deleted in colorectal carcinoma' (DCC), which has been implicated in congenital mirror movements when it is mutated in the heterozygous state but whose biallelic loss-of-function human phenotype has not been reported...
February 27, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28242615/cyp24a1-attenuation-limits-progression-of-brafv600e-induced-papillary-thyroid-cancer-cells-and-sensitizes-them-to-brafv600e-inhibitor-plx4720
#12
Minjing Zou, Essa Y Baitei, Huda BinEssa, Futwan A Al-Mohanna, Ranjit Parhar, Rene St-Arnaud, Shioko Kimura, Catrin A Pritchard, Ali S Alzahrani, Abdullah M Assiri, Brian Meyer, Yufei Shi
CYP24A1, the primary inactivating enzyme for vitamin D, is often overexpressed in human cancers, potentially neutralizing the antitumor effects of calcitriol, the active form of vitamin D. However, it is unclear whether CYP24A1 expression serves as a functional contributor versus only a biomarker for tumor progression. In this study, we investigated the role of CYP24A1 on malignant progression of a murine model of BrafV600E-induced papillary thyroid cancer (PTC). Mice harboring wild-type Cyp24a1 (BVECyp24a1-wt) developed PTC at 5 weeks of age...
February 27, 2017: Cancer Research
https://www.readbyqxmd.com/read/28230890/effect-of-testosterone-replacement-therapy-on-vitamin-d-and-fgf-23-levels-in-congenital-hypogonadism
#13
Cem Haymana, Alper Sonmez, Aydogan Aydogdu, Serkan Tapan, Yalcin Basaran, Coskun Meric, Kamil Baskoy, Abdullah Taslipinar, Mahmut Ilker Yilmaz, Omer Azal
INTRODUCTION: Patients with hypogonadism are at increased risk of cardiac and metabolic diseases and osteoporosis. Vitamin D and Fibroblast growth factor-23 (FGF-23) play role in the regulation of bone mineral metabolism and endothelial functions. Low vitamin D levels are reported in hypogonadism, while there is no data about the effect of testosterone replacement therapy (TRT). We investigated the effect of TRT on vitamin D and FGF-23 levels along with endothelial functions and insulin resistance in hypogonadal patients...
February 23, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28218758/variant-aware-saturating-mutagenesis-using-multiple-cas9-nucleases-identifies-regulatory-elements-at-trait-associated-loci
#14
Matthew C Canver, Samuel Lessard, Luca Pinello, Yuxuan Wu, Yann Ilboudo, Emily N Stern, Austen J Needleman, Frédéric Galactéros, Carlo Brugnara, Abdullah Kutlar, Colin McKenzie, Marvin Reid, Diane D Chen, Partha Pratim Das, Mitchel A Cole, Jing Zeng, Ryo Kurita, Yukio Nakamura, Guo-Cheng Yuan, Guillaume Lettre, Daniel E Bauer, Stuart H Orkin
Cas9-mediated, high-throughput, saturating in situ mutagenesis permits fine-mapping of function across genomic segments. Disease- and trait-associated variants identified in genome-wide association studies largely cluster at regulatory loci. Here we demonstrate the use of multiple designer nucleases and variant-aware library design to interrogate trait-associated regulatory DNA at high resolution. We developed a computational tool for the creation of saturating-mutagenesis libraries with single or multiple nucleases with incorporation of variants...
February 20, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28215850/predictors-of-adolescents-weight-misclassification-a-longitudinal-study
#15
Abdulaziz D Aloufi, Jake M Najman, Abdullah A Mamun
OBJECTIVE: To examine adolescents' and mothers' misclassification of the adolescents' body weight and associated early life predictors. METHODS: Data are from a sample of women and their children who were part of a longitudinal Australian birth cohort study. We analysed data of 3925 adolescents, 3721 mothers, and 2593 mother-offspring pairs. At the 14-year follow up, we derived adolescents' body weight category (underweight, normal or overweight) based on their measured height and weight and adolescents reported their similar subjective weight categories...
February 16, 2017: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/28210176/femtosecond-astigmatic-keratotomy-for-postkeratoplasty-astigmatism
#16
Nasser Al Sabaani, Salem Al Malki, Mohanna Al Jindan, Abdullah Al Assiri, Samar Al Swailem
PURPOSE: To evaluate the initial outcomes of femtosecond laser arcuate keratotomies (AK) to correct high astigmatism after keratoplasty. METHODS: This retrospective non-comparative interventional study included 52 consecutive patients (52 eyes) who underwent Intralase-enabled arcuate keratotomies. Changes in uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BCVA), mean refractive and keratometric astigmatism, preoperative and postoperative manifest refraction and complications were the main outcome measures...
July 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28209629/burden-of-musculoskeletal-disorders-in-the-eastern-mediterranean-region-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#17
Maziar Moradi-Lakeh, Mohammad H Forouzanfar, Stein Emil Vollset, Charbel El Bcheraoui, Farah Daoud, Ashkan Afshin, Raghid Charara, Ibrahim Khalil, Hideki Higashi, Mohamed Magdy Abd El Razek, Aliasghar Ahmad Kiadaliri, Khurshid Alam, Nadia Akseer, Nawal Al-Hamad, Raghib Ali, Mohammad AbdulAziz AlMazroa, Mahmoud A Alomari, Abdullah A Al-Rabeeah, Ubai Alsharif, Khalid A Altirkawi, Suleman Atique, Alaa Badawi, Lope H Barrero, Mohammed Basulaiman, Shahrzad Bazargan-Hejazi, Neeraj Bedi, Isabela M Bensenor, Rachelle Buchbinder, Hadi Danawi, Samath D Dharmaratne, Faiez Zannad, Maryam S Farvid, Seyed-Mohammad Fereshtehnejad, Farshad Farzadfar, Florian Fischer, Rahul Gupta, Randah Ribhi Hamadeh, Samer Hamidi, Masako Horino, Damian G Hoy, Mohamed Hsairi, Abdullatif Husseini, Mehdi Javanbakht, Jost B Jonas, Amir Kasaeian, Ejaz Ahmad Khan, Jagdish Khubchandani, Ann Kristin Knudsen, Jacek A Kopec, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Azeem Majeed, Reza Malekzadeh, Kedar Mate, Alem Mehari, Michele Meltzer, Ziad A Memish, Mojde Mirarefin, Shafiu Mohammed, Aliya Naheed, Carla Makhlouf Obermeyer, In-Hwan Oh, Eun-Kee Park, Emmanuel Kwame Peprah, Farshad Pourmalek, Mostafa Qorbani, Anwar Rafay, Vafa Rahimi-Movaghar, Rahman Shiri, Sajjad Ur Rahman, Rajesh Kumar Rai, Saleem M Rana, Sadaf G Sepanlou, Masood Ali Shaikh, Ivy Shiue, Abla Mehio Sibai, Diego Augusto Santos Silva, Jasvinder A Singh, Jens Christoffer Skogen, Abdullah Sulieman Terkawi, Kingsley N Ukwaja, Ronny Westerman, Naohiro Yonemoto, Seok-Jun Yoon, Mustafa Z Younis, Zoubida Zaidi, Maysaa El Sayed Zaki, Stephen S Lim, Haidong Wang, Theo Vos, Mohsen Naghavi, Alan D Lopez, Christopher J L Murray, Ali H Mokdad
OBJECTIVES: We used findings from the Global Burden of Disease Study 2013 to report the burden of musculoskeletal disorders in the Eastern Mediterranean Region (EMR). METHODS: The burden of musculoskeletal disorders was calculated for the EMR's 22 countries between 1990 and 2013. A systematic analysis was performed on mortality and morbidity data to estimate prevalence, death, years of live lost, years lived with disability and disability-adjusted life years (DALYs)...
February 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28198080/proteomic-profiling-of-mature-leaves-from-oil-palm-elaeis-guineensis-jacq
#18
Hooi Sin Tan, Richard P Jacoby, Meilina Ong-Abdullah, Nicolas L Taylor, Susan Liddell, Wong Wei Chee, Chiew Foan Chin
Oil palm is one of the most productive oil bearing crops grown in Southeast Asia. Due to the dwindling availability of agricultural land and increasing demand for high yielding oil palm seedlings, clonal propagation is vital to the oil palm industry. Most commonly, leaf explants are used for in vitro micropropagation of oil palm and to optimise this process it is important to unravel the physiological and molecular mechanisms underlying somatic embryo production from leaves. In this study, a proteomic approach was used to determine protein abundance of mature oil palm leaves...
February 15, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28194543/a-comparative-study-of-the-bone-contact-to-zirconium-and-titanium-implants-after-8%C3%A2-weeks-of-implantation-in-rabbit-femoral-condyles
#19
Abdullah Aldosari AlFarraj, Anil Sukumaran, D Mohammad Amri Al, Aja Bart Van Oirschot, John A Jansen
Zirconium (Zr) has been found to have comparable characteristics to titanium with a favorable modulus of elasticity. In addition, the release of Zr-ions of a Zr implant is supposed to further increase the bone-to-implant response. Therefore, the objective of this study is to compare the bone contact to Zr and Ti implants in the femoral trabecular bone of rabbits. In addition, implants provided with a hydroxyapatite (HA) coating were included, as such a coating was proven before to enhance the secondary implant stability...
February 13, 2017: Odontology
https://www.readbyqxmd.com/read/28192539/optical-coherence-tomography-segmentation-analysis-in-relapsing-remitting-versus-progressive-multiple-sclerosis
#20
Raed Behbehani, Abdullah Abu Al-Hassan, Ali Al-Salahat, Devarajan Sriraman, J D Oakley, Raed Alroughani
INTRODUCTION: Optical coherence tomography (OCT) with retinal segmentation analysis is a valuable tool in assessing axonal loss and neuro-degeneration in multiple sclerosis (MS) by in-vivo imaging, delineation and quantification of retinal layers. There is evidence of deep retinal involvement in MS beyond the inner retinal layers. The ultra-structural retinal changes in MS in different MS phenotypes can reflect differences in the pathophysiologic mechanisms. There is limited data on the pattern of deeper retinal layer involvement in progressive MS (PMS) versus relapsing remitting MS (RRMS)...
2017: PloS One
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