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https://www.readbyqxmd.com/read/28821637/ensuring-due-process-in-the-iacuc-and-animal-welfare-setting-considerations-in-developing-noncompliance-policies-and-procedures-for-institutional-animal-care-and-use-committees-and-institutional-officials
#1
REVIEW
Barbara C Hansen, Sylvia Gografe, Stacy Pritt, Kai-Lin Catherine Jen, Camille A McWhirter, Susan M Barman, Anthony Comuzzie, Molly Greene, Justin A McNulty, Daniel Eugene Michele, Naz Moaddab, Randall J Nelson, Karen Norris, Karen D Uray, Ron Banks, Karin N Westlund, Bill J Yates, Jerald Silverman, Kenneth D Hansen, Barbara Redman
Every institution that is involved in research with animals is expected to have in place policies and procedures for the management of allegations of noncompliance with the Animal Welfare Act and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. We present here a model set of recommendations for institutional animal care and use committees and institutional officials to ensure appropriate consideration of allegations of noncompliance with federal Animal Welfare Act regulations that carry a significant risk or specific threat to animal welfare...
August 15, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28821197/regional-variability-in-percentage-of-breast-cancers-reported-as-positive-for-her2-in-california-implications-of-patient-demographics-on-laboratory-benchmarks
#2
Chieh-Yu Lin, Eugene E Carneal, Daphne Y Lichtensztajn, Scarlett L Gomez, Christina A Clarke, Kristin C Jensen, Allison W Kurian, Kimberly H Allison
Objectives: The expected regional variability in percent human epidermal growth factor receptor 2 (HER2)-positive breast cancers is not currently clear. Methods: Data from the 2006 to 2011 California Cancer Registry were examined by county and health service area. The influence of demographic and pathologic features was used in a multivariable logistic regression model to compare expected with observed HER2-positive percentages by region. Results: There was significant geographic variation by California counties (11...
September 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28820340/effect-of-support-supervision-on-maternal-and-newborn-health-services-and-practices-in-rural-eastern-uganda
#3
Angela N Kisakye, Rornald Muhumuza Kananura, Elizabeth Ekirapa-Kiracho, John Bua, Martha Akulume, Gertrude Namazzi, Suzanne Namusoke Kiwanuka
BACKGROUND: Support supervision is one of the strategies used to check the quality of services provided at health facilities. From 2013 to 2015, Makerere University School of Public Health strengthened support supervision in the district of Kibuku, Kamuli and Pallisa in Eastern Uganda to improve the quality of maternal and newborn services. OBJECTIVE: This article assesses quality improvements in maternal and newborn care services and practices during this period...
August 2017: Global Health Action
https://www.readbyqxmd.com/read/28818397/life-cycle-inventory-and-mass-balance-of-municipal-food-waste-management-systems-decision-support-methods-beyond-the-waste-hierarchy
#4
Joel Edwards, Maazuza Othman, Enda Crossin, Stewart Burn
When assessing the environmental and human health impact of a municipal food waste (FW) management system waste managers typically rely on the principles of the waste hierarchy; using metrics such as the mass or rate of waste that is 'prepared for recycling,' 'recovered for energy,' or 'sent to landfill.' These metrics measure the collection and sorting efficiency of a waste system but are incapable of determining the efficiency of a system to turn waste into a valuable resource. In this study a life cycle approach was employed using a system boundary that includes the entire waste service provision from collection to safe end-use or disposal...
August 14, 2017: Waste Management
https://www.readbyqxmd.com/read/28817303/chrna7-deletions-are-enriched-in-risperidone-treated-children-and-adolescents
#5
Madelyn A Gillentine, Janson J White, Christopher M Grochowski, James R Lupski, Christian P Schaaf, Chadi A Calarge
OBJECTIVE: Aggression is among the most common indications for referral to child and adolescent mental health services and is often challenging to treat. Understanding the biological underpinnings of aggression could help optimize treatment efficacy. Neuronal nicotinic acetylcholine receptors (nAChRs), specifically the α7 nAChR, encoded by the gene CHRNA7, have been implicated in aggressive behaviors in animal models as well as humans. Copy number variants (CNVs) of CHRNA7 are found in individuals with neuropsychiatric disorders, often with comorbid aggression...
August 17, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28816578/cost-analysis-of-telerehabilitation-after-arthroscopic-subacromial-decompression
#6
Jose Manuel Pastora-Bernal, Rocío Martín-Valero, Francisco Javier Barón-López
Background Subacromial impingement syndrome poses a substantial socioeconomic burden, leading to significant consumption of healthcare. Health systems are calling for greater evidence of economic impacts of particular healthcare services. Telerehabilitation programmes have the potential to reduce costs and improve patient access as an alternative to traditional care. Cost analysis has been traditionally included in study protocols and results, although the reliability and research methodology have frequently been under debate...
January 1, 2017: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/28816220/incidents-of-violence-against-doctors-in-india-can-these-be-prevented
#7
Neeraj Nagpal
Violence against doctors is on the rise all over the world. However, India has a unique problem. Meagre government spending on healthcare has resulted in poor infrastructure and human resource crunch in government hospitals. Hence, people are forced to seek private healthcare. Small and medium private healthcare establishments, which provide the bulk of healthcare services, are isolated, disorganized and vulnerable to violence. Violence against health service providers is only a manifestation of this malady...
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28816103/assessment-of-work-related-accidents-associated-with-waste-handling-in-belo-horizonte-brazil
#8
Marcos Pg Mol, Amanda F Pereira, Dirceu B Greco, Sandy Cairncross, Leo Heller
As more urban solid waste is generated, managing it becomes ever more challenging and the potential impacts on the environment and human health also become greater. Handling waste - including collection, treatment and final disposal - entails risks of work accidents. This article assesses the perception of waste management workers regarding work-related accidents in domestic and health service contexts in Belo Horizonte, Brazil. These perceptions are compared with national data from the Ministry of Social Security on accidents involving workers in solid waste management...
August 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28815837/cost-of-asthma-in-children-a-nationwide-population-based-cost-of-illness-study
#9
Manuel José Ferreira de Magalhães, Rita da Silva Amaral, Ana Margarida Pereira, Ana Isabel Alves de Sá E Sousa Santos, Maria Inês Águeda de Azevedo, Luís Filipe Ribeiro de Azevedo, João Almeida Lopes Fonseca
BACKGROUND: Childhood asthma is very prevalent and costs can be high, especially in severe disease. This study aimed to estimate the cost of asthma in Portuguese children and the variations by level of asthma control. METHODS: A nationwide, population- and prevalence-based cost-of-illness study with a societal perspective was conducted. We measured direct and indirect costs using a bottom-up approach and a human capital method, respectively, for 208 children (<18 years), from two national repositories...
August 17, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28814532/developmental-process-and-early-phases-of-implementation-for-the-us-interagency-committee-on-human-nutrition-research-national-nutrition-research-roadmap-2016-2021
#10
Sheila E Fleischhacker, Rachel M Ballard, Pamela E Starke-Reed, Deborah A Galuska, Marian L Neuhouser
The Interagency Committee on Human Nutrition Research (ICHNR) is charged with improving the planning, coordination, and communication among federal agencies engaged in nutrition research and with facilitating the development and updating of plans for federal research programs to meet current and future domestic and international needs for nutrition. The ICHNR is co-chaired by the USDA Under Secretary for Research, Education, and Economics and Chief Scientist and the US Department of Health and Human Services Assistant Secretary for Health and is made up of >10 departments and agencies...
August 16, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28814120/how-east-germany-fabricated-the-myth-of-hiv-being-man-made
#11
Anders Jeppsson
Despite the fact that the origin of human immunodeficiency virus (HIV) being a contamination and a mutation originating from primates is well-documented alternative narratives are often being heard ofespecially in sub-Saharan Africa. One such narrative is about HIV being man-made in a military laboratory in the United States. In this article, it is shown how this narrative was fabricated by the intelligence services in East Germany (German Democratic Republic - GDR) as part of the ideological warfare during the Cold War...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28813929/soft-brain-machine-interfaces-for-assistive-robotics-a-novel-control-approach
#12
Lucia Schiatti, Jacopo Tessadori, Giacinto Barresi, Leonardo S Mattos, Arash Ajoudani
Robotic systems offer the possibility of improving the life quality of people with severe motor disabilities, enhancing the individual's degree of independence and interaction with the external environment. In this direction, the operator's residual functions must be exploited for the control of the robot movements and the underlying dynamic interaction through intuitive and effective human-robot interfaces. Towards this end, this work aims at exploring the potential of a novel Soft Brain-Machine Interface (BMI), suitable for dynamic execution of remote manipulation tasks for a wide range of patients...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812890/jaqpot-quattro-a-novel-computational-web-platform-for-modelling-and-analysis-in-nanoinformatics
#13
Charalampos Chomenidis, Georgios Drakakis, Georgia Tsiliki, Evangelia Anagnostopoulou, Angelos Valsamis, Philip Doganis, Pantelis Sopasakis, Haralambos Sarimveis
Engineered nanomaterials (ENMs) are increasingly infiltrating our lives due to their applications across multiple fields. However, ENM formulations may result in the modulation of pathways and mechanisms of toxic action that endanger human health and the environment. Alternative testing methods such as in silico approaches are becoming increasingly popular for assessing the safety of ENMs as they are cost- and time- effective. Additionally, computational approaches support the industrial safer-by-design challenge and the REACH legislation objective of reducing animal testing...
August 16, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28812841/university-of-global-health-equity-s-contribution-to-the-reduction-of-education-and-health-services-rationing
#14
EDITORIAL
Agnes Binagwaho
The inadequate supply of health workers and demand-side barriers due to clinical practice that heeds too little attention to cultural context are serious obstacles to achieving universal health coverage and the fulfillment of the human rights to health, especially for the poor and vulnerable living in remote rural areas. A number of strategies have been deployed to increase both the supply of healthcare workers and the demand for healthcare services. However, more can be done to improve service delivery as well as mitigate the geographic inequalities that exist in this field...
May 29, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812836/understanding-internal-accountability-in-nigeria-s-routine-immunization-system-perspectives-from-government-officials-at-the-national-state-and-local-levels
#15
Daniel J Erchick, Asha S George, Chukwunonso Umeh, Chizoba Wonodi
BACKGROUND: Routine immunization coverage in Nigeria has remained low, and studies have identified a lack of accountability as a barrier to high performance in the immunization system. Accountability lies at the heart of various health systems strengthening efforts recently launched in Nigeria, including those related to immunization. Our aim was to understand the views of health officials on the accountability challenges hindering immunization service delivery at various levels of government...
December 10, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812822/how-could-private-healthcare-better-contribute-to-healthcare-coverage-in-vietnam
#16
Mai Phuong Nguyen, Andrew Wilson
Private healthcare services in Vietnam are seen as a major part of the solution to the rapid increase in need and demand for healthcare services. Formally recognized over 20 years ago, the private health services coexist with public services and are available all over the country. However, the scale and size of private sector is still small compared to the public sector and public acceptance and reputation still limited. There are substantial concerns with the quality of services and the adequacy of regulation...
January 22, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812804/barriers-to-the-implementation-of-the-health-and-rehabilitation-articles-of-the-united-nations-convention-on-the-rights-of-persons-with-disabilities-in-south-africa
#17
Meghan Hussey, Malcolm MacLachlan, Gubela Mji
BACKGROUND: The United Nations (UN) Convention on the Rights of Persons with Disabilities (CRPD) is a milestone in the recognition of the human rights of persons with disabilities, including the right to health and rehabilitation. South Africa has signed and ratified the CRPD but still has a long way to go in reforming policies and systems in order to be in compliance with the convention. This paper seeks to fill a gap in the literature by exploring what the barriers to the implementation of the health and rehabilitation articles of the CRPD are, as identified by representatives of the disability community...
August 28, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812672/rapid-and-direct-recoveries-of-predators-and-prey-through-synchronized-ecosystem-management
#18
Jameal F Samhouri, Adrian C Stier, Shannon M Hennessey, Mark Novak, Benjamin S Halpern, Phillip S Levin
One of the twenty-first century's greatest environmental challenges is to recover and restore species, habitats and ecosystems. The decision about how to initiate restoration is best-informed by an understanding of the linkages between ecosystem components and, given these linkages, an appreciation of the consequences of choosing to recover one ecosystem component before another. However, it remains difficult to predict how the sequence of species' recoveries within food webs influences the speed and trajectory of restoration, and what that means for human well-being...
March 1, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812661/human-population-growth-offsets-climate-driven-increase-in-woody-vegetation-in-sub-saharan-africa
#19
Martin Brandt, Kjeld Rasmussen, Josep Peñuelas, Feng Tian, Guy Schurgers, Aleixandre Verger, Ole Mertz, John R B Palmer, Rasmus Fensholt
The rapidly growing human population in sub-Saharan Africa generates increasing demand for agricultural land and forest products, which presumably leads to deforestation. Conversely, a greening of African drylands has been reported, but this has been difficult to associate with changes in woody vegetation. There is thus an incomplete understanding of how woody vegetation responds to socio-economic and environmental change. Here we used a passive microwave Earth observation data set to document two different trends in land area with woody cover for 1992-2011: 36% of the land area (6,870,000 km(2)) had an increase in woody cover largely in drylands, and 11% had a decrease (2,150,000 km(2)), mostly in humid zones...
March 6, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28810978/factors-associated-with-medical-school-entrants-interest-in-military-financial-assistance-in-exchange-for-a-service-obligation-the-michigan-state-university-college-of-human-medicine-cohort
#20
Dean G Sienko, Kathleen Oberst
INTRODUCTION: The U.S. military offers comprehensive scholarships to medical students to help offset costs in exchange for either reserve or active duty service commitments. Our goal was to describe to what degree newly admitted students to Michigan State University's College of Human Medicine were aware of and interested in these opportunities. MATERIALS AND METHODS: We surveyed 176 newly admitted students at the beginning and immediately following a presentation on military medicine opportunities...
July 2017: Military Medicine
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