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https://www.readbyqxmd.com/read/29350600/long-term-outcome-of-pallidal-stimulation-for-meige-syndrome
#1
Shiro Horisawa, Taku Ochiai, Shinichi Goto, Takeshi Nakajima, Nobuhiko Takeda, Takakazu Kawamata, Takaomi Taira
OBJECTIVE Meige syndrome is characterized by blepharospasm and varied subphenotypes of craniocervical dystonia. Current literature on pallidal surgery for Meige syndrome is limited to case reports and a few small-scale studies. The authors investigated the clinical outcomes of deep brain stimulation (DBS) of the globus pallidus internus (GPi) in patients with Meige syndrome. METHODS Sixteen patients who underwent GPi DBS at the Tokyo Women's Medical University Hospital between 2002 and 2015 were included in this study...
January 19, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29339959/medical-cannabis-a-beneficial-high-in-treatment-of-blepharospasm-an-early-observation
#2
Phillip M Radke, Ali Mokhtarzadeh, Michael S Lee, Andrew R Harrison
The objective of this study was to observe the effect of medical cannabis in benign essential blepharospasm (BEB) as an adjunct to botulinum toxin. A retrospective chart review was performed on patients certified for medical cannabis use for BEB from September 2015 to May 2016. Patient demographics and responses, cannabis history, and severity indices were collected. Ten patients were certified for medical cannabis use. Five met the inclusion criteria, which was any patient with a diagnosis of BEB receiving standard botulinum toxin treatment who had started medical cannabis treatment by a registered distributor within the state, and was contactable by phone...
October 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29322963/botulinum-toxin-in-meige-s-syndrome-a-video-based-case-series
#3
Sanjay Pandey, Soumya Sharma
CONTEXT: Despite being the most common cause of cranial dystonia, Meige's syndrome remains a rare clinical entity. Characterized by blepharospasm and orofacial dystonia, patients suffering from Meige's syndrome benefit from the injection of botulinum toxin (BTX). AIMS: As the majority of the studies tend to discuss Meige's syndrome with blepharospasm patients, there is a paucity of case-based studies dealing exclusively with this syndrome. Hence, we intended to characterize and define the evolution of this syndrome and objectively determine the response of the patients suffering from this entity to BTX therapy...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29286305/muscle-selection-for-focal-limb-dystonia
#4
REVIEW
Barbara Illowsky Karp, Katharine Alter
Selection of muscles for botulinum toxin injection for limb dystonia is particularly challenging. Limb dystonias vary more widely in the pattern of dystonic movement and involved muscles than cervical dystonia or blepharospasm. The large variation in how healthy individuals perform skilled hand movements, the large number of muscles in the hand and forearm, and the presence of compensatory actions in patients with dystonia add to the complexity of choosing muscles for injection. In this article, we discuss approaches to selecting upper and lower extremity muscles for chemodenervation treatment of limb dystonia...
December 29, 2017: Toxins
https://www.readbyqxmd.com/read/29246604/long-term-clinical-outcome-of-bilateral-pallidal-stimulation-for-intractable-craniocervical-dystonia-meige-syndrome-report-of-6-patients
#5
Michał Sobstyl, Grażyna Brzuszkiewicz-Kuźmicka, Artur Zaczyński, Tomasz Pasterski, Marta Aleksandrowicz, Mirosław Ząbek
BACKGROUND: The aim of the present study was to report the short-term as well long-term results of bilateral pallidal stimulation in 6 consecutive patients for severe debilitating craniocervical dystonia (Meige syndrome) using Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS). METHODS: We evaluated 6 consecutive patients with the diagnosis of intractable long-standing craniocervical dystonia. The formal objective assessment included the motor and disability BFMDRS scores...
December 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29239881/the-facial-nerve-and-selective-neurectomy-for-treatment-of-benign-essential-blepharospasm
#6
Christopher Weller, Ilya Leyngold
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239879/secondary-blepharospasm-associated-with-ocular-surface-disease
#7
Seong Lee, Michael T Yen
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239878/surgical-myectomy-for-essential-blepharospasm-and-hemifacial-spasm
#8
Michael T Yen
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239877/botulinum-toxins-for-treating-essential-blepharospasm-and-hemifacial-spasm
#9
Daniel J Ozzello, Joseph N Giacometti
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239876/oral-pharmacotherapy-for-benign-essential-blepharospasm
#10
Kristin E Hirabayashi, M Reza Vagefi
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239875/the-benign-essential-blepharospasm-research-foundation
#11
Grant H Moore, Richard L Anderson
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239874/benign-essential-blepharospasm-what-we-know-and-what-we-don-t
#12
Christopher J Hwang, Kian Eftekhari
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239873/the-history-of-blepharospasm-in-medicine
#13
Eric B Hamill, Michael T Yen
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29239872/blepharospasm-and-hemifacial-spasm
#14
Michael T Yen
No abstract text is available yet for this article.
2018: International Ophthalmology Clinics
https://www.readbyqxmd.com/read/29234300/temporal-discrimination-mechanisms-and-relevance-to-adult-onset-dystonia
#15
REVIEW
Antonella Conte, Eavan M McGovern, Shruti Narasimham, Rebecca Beck, Owen Killian, Sean O'Riordan, Richard B Reilly, Michael Hutchinson
Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as being asynchronous; this can be assessed, with high test-retest and inter-rater reliability, using a simple psychophysical test. Temporal discrimination is disordered in a number of basal ganglia diseases including adult-onset dystonia, of which the two most common phenotypes are cervical dystonia and blepharospasm...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29204316/acute-dystonic-reaction-following-general-anesthetic-agent-use
#16
Jiraporn Jitprapaikulsan, Prachaya Srivanitchapoom
Background: A 36-year-old Thai female who underwent a thymectomy under general anesthesia developed acute abnormal movements in the craniofacial region immediately after awakening with preserved consciousness. Phenomenology: Intermittent abnormal movements included oculogyric crisis; tongue protrusion; blepharospasm; and oro-mandibular dystonia consisting of risus sardonicus, jaw opening, and right torticollis. Educational value: An acute dystonic reaction can be a complication of either single or combined general anesthetic agents...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/29145580/effect-of-botulinum-toxin-a-on-muscle-healing-and-its-implications-in-aesthetic-and-reconstructive-surgery
#17
Eldad Silberstein, Ehud Maor, Oleg Sukmanov, Alexander Bogdanov Berezovsky, Yaron Shoham, Yuval Krieger
Background: Muscle activity contributes to the enhancement of facial aging deformity, blepharospasm, cerebral palsy spasticity, trismus, torticollis, and other conditions. Myotomy of the involved muscles in order to reduce the deformity has variable success rates due to muscle healing and regeneration of activity. Objectives: The goal of this study was to investigate whether blocking striated muscle activity with Botulinum toxin (BtxA) during the healing time after myotomy alters the healing process and reduces long-term muscle activity...
November 14, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29145188/brueghel-syndrome-or-meige-syndrome-two-sides-of-a-same-disease
#18
M Béreau, L Tatu
Different eponyms such as "Wood syndrome," Meige syndrome, "Brueghel syndrome," "Blepharospasm plus syndrome" have been used to describe segmental craniocervical dystonias. These facial and/or oromandibular movement disorders are characterized by muscle contractions and spasms involving eyes, facial region, and sometimes pharynx, jaw, floor of the mouth, and tongue. The pathophysiology of craniocervical dystonia is poorly understood, but abnormal plasticity and impaired inhibition are suspected. Injection of botulinum toxin appears to be the best therapeutic option for treating segmental craniocervical dystonia...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29135814/neuro-ophthalmology-at-a-tertiary-eye-care-centre-in-india
#19
Rebika Dhiman, Digvijay Singh, Shiva P Gantayala, Vaitheeswaran L Ganesan, Pradeep Sharma, Rohit Saxena
BACKGROUND: Neuro-ophthalmology as a specialty is underdeveloped in India. The aim of our study was to determine the spectrum and profile of patients presenting to a tertiary eye care center with neuro-ophthalmic disorders. METHODS: A retrospective hospital-based study was conducted, and records of all patients seen at the neuro-ophthalmology clinic of Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India, over a 1-year period were retrieved and evaluated...
November 9, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29116410/botulinum-toxin-therapy-in-patients-with-oral-anticoagulation-is-it-safe
#20
Christoph Schrader, Markus Ebke, Fereshte Adib Saberi, Dirk Dressler
When used therapeutically, botulinum toxin (BT) has to be injected into its target tissues. All manufacturers warn not to do so in patients with oral anticoagulation to avoid haematoma. We wanted to study the haematoma frequency (HF) in patients with anticoagulation receiving BT therapy. 32 patients (16 females, 16 males, age 69.3 ± 10.0 years) with blepharospasm (n = 6), hemifacial spasm (n = 8), post-stroke spasticity (n = 16), and cervical dystonia (n = 2) received BT therapy (needle size 27G, post-injection tissue compression) whilst on anticoagulation (anticoagulation group, AG)...
November 7, 2017: Journal of Neural Transmission
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