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hydrops corneal

Akilesh Gokul, Dipika V Patel, Grant A Watters, Charles N J McGhee
BACKGROUND/AIMS: To determine if significant progression of disease occurs in older, non-contact lens wearing, subjects with keratoconus and to identify potential predictive factors. METHODS: Clinical and computerised corneal topography records of subjects with keratoconus attending a specialist optometry practice were retrospectively analysed to identify those aged ≥30 years, with ≥2 consultations ≥12 months apart, no contact lens wear and no corneal scarring, surgery or corneal hydrops...
October 11, 2016: British Journal of Ophthalmology
Meiyan Feng, Chao Wang
To the best of our knowledge, there have been no reports of corneal hydrops associated with diabetic ketoacidosis. The present study first reports a case of a 20-year-old male patient with diabetic ketoacidosis-induced corneal hydrops. The patient exhibited mild hydrops in their left eyelid, which was accompanied by mixed hyperemia, and hazy turbid in a white color was observed in the cornea. To alleviate the corneal hydrops, 5% glucose was administered dropwise to the left eye for 2 h to alleviate the inflammation...
September 2016: Experimental and Therapeutic Medicine
Sylvain El-Khoury, Youssef Abdelmassih, Adib Hamade, Elise Slim, Carole G Cherfan, Elias Chelala, Jamal Bleik, Elias F Jarade
PURPOSE: To report the incidence, clinical presentation, risk factors, and treatment outcome of pediatric keratoconus in a tertiary referral eye hospital in Beirut, Lebanon. METHODS: In this retrospective study, the authors evaluated all patients with keratoconus 14 years or younger newly diagnosed at the Beirut Eye Specialist Hospital, Beirut, Lebanon, between January 2010 and December 2014. The incidence of pediatric keratoconus among all pediatric patients and among patients with keratoconus of all ages was assessed...
August 1, 2016: Journal of Refractive Surgery
Jay J Meyer, Akilesh Gokul, Alexandra Z Crawford, Charles N J McGhee
PURPOSE: To evaluate the long-term risk of endothelial rejection, graft survival, and associated factors following penetrating keratoplasty (PK) for keratoconus, with and without prior resolved corneal hydrops. DESIGN: Retrospective cohort study. METHODS: Primary outcome measures were endothelial rejection-free survival and failure-free survival. Secondary outcome measures were corneal neovascularization following hydrops and complications following PK...
September 2016: American Journal of Ophthalmology
Hisataka Fujimoto, Naoyuki Maeda, Ayumi Shintani, Tomoya Nakagawa, Mutsumi Fuchihata, Ritsuko Higashiura, Kohji Nishida
PURPOSE: We quantified the chronologic progression of keratoconus using anterior segment optical coherence tomography (AS-OCT). METHODS: A total of 217 eyes from 113 patients with keratoconus, keratoconus suspect, or forme fruste keratoconus were evaluated by corneal tomography using swept-source OCT. Age-dependent changes in the radius of the posterior best-fit sphere (Rpost), minimum corneal thickness (Tmin), and distance from the thinnest point to the corneal vertex (Dmin) were examined over follow-up periods of up to 5...
July 1, 2016: Investigative Ophthalmology & Visual Science
Allon Barsam, Nic Brennan, Harry Petrushkin, Wen Xing, Ana Quartilho, Catey Bunce, Barny Foot, Nathaniel Knox Cartwright, Anjana Haridas, Pavi Agrawal, Hanif Suleman, Sajjad Ahmad, Elisabeth MacDonald, Jennifer Johnston, Stephen Tuft
PURPOSE: To determine risk factors for the development of acute corneal hydrops in keratoconus in the UK in a case-controlled study. METHODS: Between November 2009 and December 2010, we prospectively identified 73 individuals who developed acute corneal hydrops. We then identified 174 controls from nine regions in the UK with keratoconus who had not had hydrops. For cases and controls we recorded demographics and clinical features. Univariate and multivariable logistic regressions were performed to identify risk factors...
July 7, 2016: British Journal of Ophthalmology
B Seitz, N Szentmáry, A Langenbucher, T Hager, A Viestenz, E Janunts, M El-Husseiny
For patients with keratoconus, rigid gas-permeable contact lenses are the first line correction method and allow good visual acuity for quite some time. In severe stages of the disease with major cone-shaped protrusion of the cornea, even specially designed keratoconus contact lenses are no longer tolerated. If there are contraindications for intrastromal ring segments, corneal transplantation typically has a very good prognosis. In patients with advanced keratoconus - especially after corneal hydrops due to rupture of Descemet's membrane - penetrating keratoplasty (PKP) is still the first line surgical method...
June 2016: Klinische Monatsblätter Für Augenheilkunde
Anil K Mandal
PURPOSE: Relatively little data exist regarding the outcomes of children with primary infantile glaucoma presenting with acute corneal hydrops. The aim of our study was to determine the surgical outcome of children of infantile glaucoma who presented with acute corneal hydrops. METHODS: In total, 38 eyes of 31 consecutive children of infantile glaucoma presented with acute corneal hydrops who underwent primary combined trabeculotomy-trabeculectomy (CTT) by a single surgeon from January 1990 to December 2012 at the LV Prasad Eye Institute (LVPEI), a tertiary eye care centre in Southern India were enrolled in this retrospective study...
2016: PloS One
Jay J Meyer, Charles N J McGhee
PURPOSE: Acute corneal hydrops is a rare complication of keratoconus and may be a risk factor for further complications such as microbial keratitis. METHODS: Retrospective, case series. RESULTS: Six eyes developed microbial keratitis during acute corneal hydrops. Risk factors for the development of microbial keratitis included epithelial defect, contact lens wear, trichiasis, and use of topical steroids. Two eyes developed corneal perforation and 1 eye was treated for possible endophthalmitis...
July 2016: Cornea
Rafic Antonios, Ali Dirani, Ali Fadlallah, Elias Chelala, Adib Hamadeh, Elias Jarade
This case report describes a 15-year-old male with allergic conjunctivitis and keratoconus, who underwent uneventful intra-corneal ring segment (ICRS) implantation and corneal collagen cross-linking (CXL) in the right eye. During the follow-up periods, the patient was noted to have several episodes of allergic conjunctivitis that were treated accordingly. At the 2 years postoperatively, he presented with another episode of allergic conjunctivitis and progression of keratoconus was suspected on topography. However, the patient was lost to follow-up, until he presented with acute hydrops at 3 years postoperatively...
January 2016: Middle East African Journal of Ophthalmology
Hatim Batawi, Nikisha Kothari, Andrew Camp, Luis Bernhard, Carol L Karp, Anat Galor
PURPOSE: We report the case of a 77-year-old man with no history of keratoconus or other ectatic disorders who presented with corneal hydrops in the setting of a corneal ulcer. The risk factors, pathogenesis and treatment options of corneal hydrops are discussed. METHOD: This is an observational case report study. RESULTS: A 77-year-old man presented with a 1-day history of severe pain, redness, mucous discharge and photophobia in the right eye...
January 2016: Case Reports in Ophthalmology
Samantha L Pederson, Stefano Pizzirani, Stacy E Andrew, Diana O Pate, Jessica M Stine, Tammy M Michau
OBJECTIVE: To evaluate the effectiveness of the use of a nictitating membrane flap (NMF) as therapy in 19 cats (21 eyes) affected with feline acute corneal hydrops (FACH). METHODS: Medical records from 19 cats diagnosed with FACH and treated with a NMF were retrospectively evaluated. Information was collected from multiple veterinary hospitals and included signalment, medical history, therapy, and ocular outcome. RESULTS: Breeds included 13 Domestic Shorthairs, 2 Exotic Shorthairs, 2 Maine Coons, 1 Persian, and 1 Domestic Medium Hair...
July 2016: Veterinary Ophthalmology
S S M Fung, F Aiello, V Maurino
PURPOSE: To evaluate the long-term outcomes after femtosecond laser (FSL)-assisted mushroom-configuration keratoplasty in advanced keratoconus. PATIENTS AND METHODS: Thirteen eyes with Amsler-Krumeich stage IV keratoconus underwent FSL-assisted mushroom-configuration penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK) at a tertiary referral centre. Preoperative risk factors included low orneal thickness, high keratometry measurements, previous hydrops, and central stromal scarring...
April 2016: Eye
Meisha L Raven, Maria E Rodriquez, Sarah M Nehls
No abstract text is available yet for this article.
December 2015: Ophthalmology
Emrah Utku Kabatas, Pinar Altiaylik Ozer, Bengi Ece Kurtul, Serdar Beken, Aysegul Zenciroglu, Nurullah Okumus
A premature baby who was hospitalized with the diagnosis of sepsis was treated with diode laser photocoagulation for aggressive posterior retinopathy of prematurity. Diffuse corneal ectasia and corneal hydrops developed in the right eye, and hyphema and corneal hydrops developed on the left eye on postoperative day 12. The patient died because of cardiovascular collapse and hemodynamic instability. Sepsis may be a contributory factor to the clinical susceptibility of the patient for the postoperative corneal effects of the laser...
October 2015: Ophthalmic Surgery, Lasers & Imaging Retina
Jennifer C Fan Gaskin, I-Ping Loh, Charles N J McGhee, Trevor Sherwin
PURPOSE: To determine the inflammatory cell and matrix changes in advanced keratoconus, including acute hydrops, using immunohistochemical analysis. METHODS: The corneal tissue from eight subjects with keratoconus undergoing corneal transplantation (three keratoconic buttons, five buttons post acute hydrops—one of them with extensive neovascularization following hydrops) was compared with tissue from two normal corneoscleral rims (n = 10). The corneas were sectioned and analyzed with specific markers for macrophages, lymphocytes, dendritic cells, and scar associated matrix molecules laminin, fibronectin, tenascin-C, and type III collagen...
September 2015: Investigative Ophthalmology & Visual Science
Vipul Bhandari, Sri Ganesh
PURPOSE: To report an unusual presentation of pellucid marginal degeneration (PMD) and its management by using air injection and tension sutures. CASE REPORT: We report 2 cases with a history of acute pain and loss of vision. Examination revealed hydrops at the 6-9 o'clock meridian with Descemet's membrane detachment and tear at the same area and advanced PMD in the other eye. DISCUSSION: Air injection with suturing to treat the hydrops in PMD and crescentic excision with lamellar grafting instead of lamellar keratoplasty lead to better results than conservative management...
May 2015: Case Reports in Ophthalmology
Georgia Avgitidou, Sebastian Siebelmann, Bjoern Bachmann, Juergen Kohlhase, Ludwig M Heindl, Claus Cursiefen
A 3-year-old boy presented with acute corneal hydrops on the left eye and spontaneous corneal rupture on the right eye. A diagnosis of brittle cornea syndrome was confirmed by molecular analysis. A novel mutation, the homozygous variant c.17T>G, p.V6G, was found in the gene for PR-domain-containing protein 5 (PRDM5) in exon 1. Brittle cornea syndrome is a rare connective tissue disease with typical ocular, auditory, musculoskeletal, and cutaneous disorders. Almost all patients suffer from declined vision due to corneal scarring, thinning, and rupture...
2015: Case Reports in Ophthalmological Medicine
Asim V Farooq, Ketki Soin, Samantha Williamson, Charlotte E Joslin, Maria S Cortina, Elmer Y Tu
PURPOSE: To report the association of chronic ocular hypotony with the development of progressive corneal ectasia and hydrops. METHODS: Retrospective case series. RESULTS: Three patients with ocular hypotony were referred for corneal evaluation and found to have ectasia and acute corneal hydrops in their hypotonous eye(s). Clinically, the globes were easily deformable with either external digital palpation and/or simple blinking. All 3 patients had a history of chronic iridocyclitis, including one with juvenile idiopathic arthritis...
September 2015: Cornea
Esteban Fuentes, Otman Sandali, Mohamed El Sanharawi, Elena Basli, Taous Hamiche, Isabelle Goemaere, Vincent Borderie, Nacim Bouheraoua, Laurent Laroche
PURPOSE: To define the optical coherence tomography (OCT) corneal changes predisposing to acute corneal hydrops among patients with advanced keratoconus. DESIGN: Retrospective cohort study. PARTICIPANTS: A total of 191 advanced keratoconic eyes from 191 patients with advanced keratoconus cases were studied. METHODS: Data collected from patients with advanced keratoconus cases were studied during a minimum period of 24 months of follow-up...
August 2015: Ophthalmology
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