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portal hypertention

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In 14 patients with cirrhosis and portal hypertention autologous mesenclyme multipotential stem cells (AMMSC) transplanation was performed in portal vein (I group, n=7) and common trunk of the hepatic artery (II group, n=6). Duration of pathological processes since diagnosis is 1-8 years (3,7±2,4 years). The initial severity was evaluated by a set of child-Pugh score: Class A - 6 (42,9%), Class B - 8 (57,1%). Cell cultures indentication and characteristics consistent with International Society of cell technology guidanes (ISCT) since 2006...
September 2014: Georgian Medical News
Atsuhiro Matsumoto, Yuji Fujino
Living-donor liver transplantation has become a standard and effective treatment for end stage liver disease patients. As a result of remarkable progress in immunosuppressive drugs, surgical device, anesthetics, and appropriate perioperative management, liver-transplanted patients may experience fewer complications, shorter length of ICU stay, and a better overall outcome. However, unexpected perioperative complications remain substantial. Therefore, we take care in several points in perioperative period. First, we should appropriately evaluate general preoperative conditions, such as coagulopathy, ascites, respiratory and renal function...
May 2014: Masui. the Japanese Journal of Anesthesiology
A G Shertsinger, S B Zhigalova, V M Lebezev, G V Manukian, E A Kitsenko
The article highlights modern approaches to the treatment of portal hypertension. The differential tactics is based on the type of portal hypertension, functional liver state, urgency of the situation and severity of blood loss, localization and stage of varices, concomitant diseases, etc. The role of miniinvasive methods is stressed. The reasonability of general treatment algorithm of portal hypertention in specialized centers is proved.
2013: Khirurgiia
Arshad Hussain Wani, Omar Javed Shah, S A Zargar
Extrahepatic portal venous obstruction (EHPVO) is a common cause of portal hypertention in children. Esophageal variceal hemorrhage is a major cause of morbidity and mortality in these patients. For many decades, portal systemic shunts were considered as the most effective treatment of variceal hemorrhage. Endoscopic injection sclerotherapy (EIS) was first introduced for emergency management of bleeding varices and subsequently as definitive treatment to prevent recurrent hemorrhage. The purpose of the study was to compare the safety and efficacy of shunt surgery and endoscopic sclerotherapy for patients with proven esophageal variceal bleeding due to EHPVO...
December 2011: Indian Journal of Surgery
S T Turmakhanov
Hypertension developing in the vena cava system under conditions of cirrhosis results in the formation of collateral blood outflow into vena cava superior (VCS) and inferior, at the same time the carrying capacity of vena cava inferior (VCI) might be limited due both to its fixation in the rigid diaphragm ring and to the fact that the hepatic segment of VCI is compressed by regenerated nodes. The increased volume of blood outflow via VCI with a simultaneous constriction of its hepatic segment results in the development of caval hypertention which even more complicates the transhepatic blood flow...
2012: Vestnik Khirurgii Imeni I. I. Grekova
T Bexten, I Burck, W O Bechstein, C Moench
HISTORY AND ADMISSION FINDINGS: A 42-year-old woman presented at our hospital, because of a non-specific hepatic tumor. She complained of dull pain in the right upper abdomen. Physical examination did not reveal any pathology, especially there was no evidence of an infection. Abuse of drugs, alcohol or anticontraceptives was also denied. INVESTIGATIONS UND THERAPY: Even though fine needle biopsy and extensive radiological examination were performed a malignant nature of the liver tumor could not be excluded...
July 2012: Deutsche Medizinische Wochenschrift
Yukiharu Hiyoshi, Toru Beppu, Kazutoshi Okabe, Hiromitsu Hayashi, Toshiro Masuda, Hirohisa Okabe, Takao Mizumoto, Hiroyuki Komori, Hiroshi Tanaka, Kei Horino, Takatoshi Ishiko, Hiroshi Takamori, Masahiko Hirota, Hideo Baba
Transcatheter arterial embolizations of severe arterioportal shunt (A-P shunt) were performed with steel coils in 3 patients with hepatocellurlar carcinoma (HCC) as shown below. Case 1: A 56-year-old man with HCC associated with portal hypertension (esophageal varices and ascites abnominal pain), portal vein tumor thrombus and severe A-P shunt was performed in critical conditions. Case 2: A 51-year-old man with HCC, lung and adrenal gland metastases was accompanied with severe portal hypertention caused by A-P shunt and was in a harmful condition similar to case 1...
November 2007: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Wu Ji, Ling-Tang Li, Jie-Shou Li
BACKGROUND: Laparoscopic cholecystectomy (LC) has become the "gold standard" in treating benign gallbladder diseases. Increasing laparoscopic experience and techniques have made laparoscopic subtotal cholecystectomy (LSC) a feasible option in more complex procedures. In recent years, few studies with a few cases of LSC have reported good results in patients with various types of cholecystitis. This study was designed to evaluate the feasibility, indications, characteristics and benefits of LSC in patients with complicated cholecystitis...
November 2006: Hepatobiliary & Pancreatic Diseases International: HBPD INT
Jérôme Boursier, Armelle Foulet, Christophe Pilette
We reported a case of nodular regenerative hyperplasia revealed by hemorrhage from portal hypertention and ascites in a 81 years old patient. This patient presented two years ago hepatic tuberculosis well documented by liver biopsy. If this patient do not have exhaustive etiologic research of nodular regenerative hyperplasia, the relationship between the tuberculosis infection and the developpement of this nodular regenerative hyperplasia appears highly probable and must be researched.
October 2005: Gastroentérologie Clinique et Biologique
Ahmed Hazem I Helmy, Afaf Ahmed Abdel-Hady, Faten el-Shanawany, Olfat Hammam, Ahmed Abdel-Hady
Schistosoma mansoni is the most prevalent cause of liver fibrosis in Egypt. It is characterized by hepatocyte damage, inflammation and chronic parasite egg-induced granuloma formation leading to fibrosis. Its management, particularly fibrosis, has focused primarily on treating and preventing the complications of portal hypertension. Unfortunately, there is no therapy that has been proved to prevent progressive hepatic fibrosis which is associated with a significant morbidity and mortality due to granulomatous hypersensitivity to parasite eggs...
December 2005: Journal of the Egyptian Society of Parasitology
Juan Gerardo Orea Martínez, Ana Cristina Obregón García, Ana María Pérez Vergara, Alberto Márquez Acosta
INTRODUCTION: SDPCS (The small diameter portacaval shunt) published originally by Rypins and Sarfeh in Los Angeles in 1983 has recieved little attention in our comunity to control bleeding in patients with portal hypertention. The bleeding of esophageal varices represents the must frequent and dramatic complication caused by cirrhosis, with a 50% of mortality without treatment. BACKGROUND: Comunicate the indications, thecnique and results with the Small Diameter Portocaval shunt...
January 2005: Revista de Gastroenterología de México
Faisal Faiyaz Zuberi, Bader Faiyaz Zuberi, Muhammad Ataullah Khan, Masood Hameed Khan
OBJECTIVE: To document the frequency of rectal varices in patients with cirrhosis of liver and compare it with that of oesophageal varices in liver and to compare the frequency of rectal varices with non-cirrhotic controls. DESIGN: A cross-sectional analytical survey. PLACE AND DURATION OF STUDY: The study was conducted in the medical wards of Civil Hospital, Karachi from August 2000 to July 2001. PATIENTS AND METHODS: All patients of confirmed cirrhosis of liver, presenting during the study period, were selected for initial workup...
February 2004: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
No abstract text is available yet for this article.
August 1960: Wiener Zeitschrift Für Innere Medizin und Ihre Grenzgebiete
X A Li, M Wang, K Lu
Microspheres were injected intraportally to block intrahepatic portal radicals and to produce a new rat model of portal hypertention. Different sized microspheres (15 microns, 40 microns, 80 microns) were injected into the portal vein. The resultant changes in arterial, portal, hepatic venous and splenic pulp pressures were monitored. The results showed that a small-dose injection of 80 microns microspheres (1.8 x 10(5)) produced a steady state portal venous pressure of 2.53 +/- 0.17 kPa, and all rats showed a normal arterial pressure...
January 1997: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
J Cai, J Dong, H Gu
The results of inferior mesenteric vein-inferior vena cava shunt coupled with splenectomy and gastroesophageal devascularization in 16 patients with cirrhotic portal hypertention were reviewed. The mean diameter of the shunt stoma was 6.46 +/- 0.78 mm, and the portal pressure decreased from 4.25 +/- 0.54 kPa to 3.39 +/- 0.41 kPa. Variceal bleeding stopped in all 16 patients with no severe postoperative complications. This procedure should preserve satisfactory portal perfusion to the liver, and technically is easier than other shunt procedures...
March 1996: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
L Aldrighetti, G Ferraroli, M Paganelli, C Graci, M Rosina, G Ferla
We describe a case of spontaneous bacterial peritonitis in a 53 year old man affected by cryptogenic micro-macronodular cirrhosis, portal hypertention, splenomegaly and hypersplenism, who was admitted with hepatic failure and septic shock and successfully treated with antibiotics (combination of clindamycin and netilmycin), surgical abdominal drainage and splenectomy. This case gave reason for a literature review and an update on the therapeutic options in these high risk patients, especially concerning the role of surgery...
August 1993: Minerva Chirurgica
R Couture, D Regoli
Vascular reactivity to angiotensin II (ATII) and noradrenaline (NA) have been studied in vivo and in femoral and renal vascular beds taken from spontaneously hypertensive rats (S.H.R.) of 3 and 5 months of age. Moreover, the stimulating effects of the same agents have been measured in strips of thoracic aortae, portal veins and stomach fundi taken from S.G.R. and from renal hypertensive rats (R.H.R.) three weeks after clamping one renal artery (two kidneys hypertention). Results obtained in animals or in organs derived from the two groups of hypertensive rats were compared with controls of the same age or of the same weight...
1980: Clinical and Experimental Hypertension
R G Farmer, R E Hermann, B H Sullivan
No abstract text is available yet for this article.
July 1969: Cleveland Clinic Quarterly
H Bismuth, D Franco
Twenty-three children under 6 years of age with portal hypertention were treated by portal diversion. Fourteen had cavernomatous transformation of the portal vein and 9 had an intrahepatic block due to cirrhosis (8) or congenital hepatic fibrosis (1). Portal-systemic shunts were central splenorenal in 20 patients, side-to-side portacaval in 2 and mesocaval in one. In 20 of the 21 peripheral shunts, the veins used for the anastomosis were less than 10 mm in diameter. There was no operative mortality. Thrombosis of the shunt occurred in 3 children (13%) and was responsible for recurrent bleeding in one who was treated later with success by a mesocaval shunt...
April 1976: Annals of Surgery
P Viallet, J F Viallet, H Fermaud
No abstract text is available yet for this article.
1975: Journal de Radiologie, D'électrologie, et de Médecine Nucléaire
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