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https://www.readbyqxmd.com/read/28324880/fine-needle-aspiration-cytology-of-diffuse-type-tenosynovial-giant-cell-tumors
#1
Zimin Zhao, Cherie Paquette, Akeesha A Shah, Kristen A Atkins, Henry F Frierson
BACKGROUND: Tenosynovial giant cell tumor (TSGCT), also known as giant cell tumor of tendon sheath or pigmented villonodular synovitis, is the most common benign tumor of the tendon and synovium. The intra-articular diffuse type can present as a large infiltrative mass involving adjacent soft tissue and sometimes causes secondary destruction of bone, which leads to radiographic and clinical concern for malignancy. The tumor may also be purely extra-articular. CASE: Here, we report the fine needle aspiration cytology findings of 2 cases of diffuse-type TSGCT with large mononuclear cells with eccentric nuclei, finely granular cytoplasm, and a peripheral well-defined cytoplasmic rim of hemosiderin ("ladybird cells")...
March 22, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28318277/technology-enhanced-human-interaction-in-psychotherapy
#2
Zac E Imel, Derek D Caperton, Michael Tanana, David C Atkins
Psychotherapy is on the verge of a technology-inspired revolution. The concurrent maturation of communication, signal processing, and machine learning technologies begs an earnest look at how these technologies may be used to improve the quality of psychotherapy. Here, we discuss 3 research domains where technology is likely to have a significant impact: (1) mechanism and process, (2) training and feedback, and (3) technology-mediated treatment modalities. For each domain, we describe current and forthcoming examples of how new technologies may change established applications...
March 20, 2017: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/28318034/tracking-the-origins-of-the-kok-effect-70-years-after-its-discovery
#3
Guillaume Tcherkez, Paul Gauthier, Thomas N Buckley, Florian A Busch, Margaret M Barbour, Dan Bruhn, Mary A Heskel, Xiao Ying Gong, Kristine Crous, Kevin L Griffin, Danielle A Way, Matthew H Turnbull, Mark A Adams, Owen K Atkin, Michael Bender, Graham D Farquhar, Gabriel Cornic
No abstract text is available yet for this article.
April 2017: New Phytologist
https://www.readbyqxmd.com/read/28299371/effect-of-mass-paediatric-influenza-vaccination-on-existing-influenza-vaccination-programmes-in-england-and-wales-a-modelling-and-cost-effectiveness-analysis
#4
David Hodgson, Marc Baguelin, Edwin van Leeuwen, Jasmina Panovska-Griffiths, Mary Ramsay, Richard Pebody, Katherine E Atkins
BACKGROUND: In 2013 England and Wales began to fund a live attenuated influenza vaccine programme for individuals aged 2-16 years. Mathematical modelling predicts substantial beneficial herd effects for the entire population as a result of reduced influenza transmission. With a decreased influenza-associated disease burden, existing immunisation programmes might be less cost-effective. The aim of this study was to assess the epidemiological effect and cost-effectiveness of the existing elderly and risk group vaccination programme under the new policy of mass paediatric vaccination in England...
February 2017: Lancet Public Health
https://www.readbyqxmd.com/read/28291725/in-situ-operating-room-based-simulation-a-review
#5
Lily Owei, Christopher J Neylan, Raghavendra Rao, Robert C Caskey, Jon B Morris, Richard Sensenig, Ari D Brooks, Daniel T Dempsey, Noel N Williams, Joshua H Atkins, Dimitry Y Baranov, Kristoffel R Dumon
OBJECTIVE: To systematically review the literature surrounding operating room-based in situ training in surgery. METHODS: A systematic review was conducted of MEDLINE. The review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, and employed the Population, Intervention, Comparator, Outcome (PICO) structure to define inclusion/exclusion criteria. The Kirkpatrick model was used to further classify the outcome of in situ training when possible...
March 10, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28288483/efficacy-of-treatments-for-infantile-spasms-a-systematic-review
#6
Ji Min Song, Jongsung Hahn, Se Hee Kim, Min Jung Chang
OBJECTIVES: West syndrome (also known as infantile spasm because of its main seizure type) is a rare form of epilepsy that begins during early infancy. Recent guidelines and reviews on West syndrome recommend the use of adrenocorticotropic hormone steroids, or vigabatrin, as the first-line treatment. However, West syndrome remains to be one of the most challenging epilepsies to treat. Here, we systematically reviewed the current literature obtained during the previous decade. This article provides an overview of the current treatment of infantile spasms...
March 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28286867/a-technology-prototype-system-for-rating-therapist-empathy-from-audio-recordings-in-addiction-counseling
#7
Bo Xiao, Chewei Huang, Zac E Imel, David C Atkins, Panayiotis Georgiou, Shrikanth S Narayanan
Scaling up psychotherapy services such as for addiction counseling is a critical societal need. One challenge is ensuring quality of therapy, due to the heavy cost of manual observational assessment. This work proposes a speech technology-based system to automate the assessment of therapist empathy-a key therapy quality index-from audio recordings of the psychotherapy interactions. We designed a speech processing system that includes voice activity detection and diarization modules, and an automatic speech recognizer plus a speaker role matching module to extract the therapist's language cues...
April 2016: PeerJ. Computer Science
https://www.readbyqxmd.com/read/28285549/methodology-of-the-access-to-care-and-timing-simulation-model-for-traumatic-spinal-cord-injury-care
#8
Argelio Santos, Nader Fallah, Rachel Lewis, Marcel F Dvorak, Michael G Fehlings, Anthony Scott Burns, Vanessa K Noonan, Christiana L Cheng, Elaine Chan, Anoushka Singh, Lise M Belanger, Derek Atkins
Despite the relatively low incidence, the management and care of persons with traumatic spinal cord injury (tSCI) can be resource intensive and complex, spanning multiple phases of care and disciplines. Using a simulation model built with a system level view of the healthcare system allows for prediction of the impact of interventions on patient and system outcomes from injury through to community reintegration after tSCI. The Access to Care and Timing (ACT) project developed a simulation model for tSCI care using techniques from operations research and its development has been described previously...
March 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28283156/dietary-therapy-and-nutrition-management-of-eosinophilic-esophagitis-a-work-group-report-of-the-american-academy-of-allergy-asthma-and-immunology
#9
Marion Groetch, Carina Venter, Isabel Skypala, Berber Vlieg-Boerstra, Kate Grimshaw, Raquel Durban, Alison Cassin, Michelle Henry, Kara Kliewer, Lynda Kabbash, Dan Atkins, Anna Nowak-Węgrzyn, Mark Holbreich, Mirna Chehade
Eosinophilic esophagitis (EoE) is a chronic/immune-antigen-mediated disease characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation. Dietary elimination therapy has been shown to be an effective, drug-free prescription for the treatment of EoE. A range of different dietary elimination therapies have been used. Regardless of the elimination diet chosen, dietary therapy requires in-depth nutrition assessment and management. Elimination diets are not without risk and may impact nutritional status, eating pleasure, and overall quality of life...
March 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28279451/data-driven-models-to-predict-the-elimination-of-sleeping-sickness-in-former-equateur-province-of-drc
#10
K S Rock, A Pandey, M L Ndeffo-Mbah, K E Atkins, C Lumbala, A Galvani, M J Keeling
Approaching disease elimination, it is crucial to be able to assess progress towards key objectives using quantitative tools. For Gambian human African trypanosomiasis (HAT), the ultimate goal is to stop transmission by 2030, while intermediary targets include elimination as a public health problem - defined as <1 new case per 10,000 inhabitants in 90% of foci, and <2000 reported cases by 2020. Using two independent mathematical models, this study assessed the achievability of these goals in the former Equateur province of the Democratic Republic of Congo, which historically had endemic levels of disease...
March 2017: Epidemics
https://www.readbyqxmd.com/read/28278333/adjuvant-treatment-for-high-risk-clear-cell-renal-cancer-updated-results-of-a-high-risk-subset-of-the-assure-randomized-trial
#11
Naomi B Haas, Judith Manola, Janice P Dutcher, Keith T Flaherty, Robert G Uzzo, Michael B Atkins, Robert S DiPaola, Toni K Choueiri
Importance: Given recently published results of a 750-patient adjuvant sunitinib trial showing improved disease-free survival (DFS), the appropriate strategy for treating high-risk patients is unclear. We sought to determine whether there is improved disease-free survival benefit to taking the active drug in patients with high-risk (pT3, pT4, node-positive) clear cell renal cancer (ccRCC) in the ASSURE trial (adjuvant sunitinib or sorafenib vs placebo in resected unfavorable renal cell carcinoma [RCC]), the largest adjuvant trial published to date...
March 9, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28271432/pharmacotherapy-for-weight-management-in-the-vha
#12
Todd P Semla, Chris Ruser, Chester B Good, Susan Z Yanovski, Donna Ames, Laurel A Copeland, Charles Billington, U Inge Ferguson, Louis J Aronne, Thomas A Wadden, W Timothy Garvey, Caroline M Apovian, David Atkins
Weight management medications (WMM) are underutilized as an adjunct to behavioral and lifestyle interventions. In fiscal years 2014-2015, a total of approximately 2500 veterans-a mere 2% of veterans receiving care from the Veterans Health Administration (VHA)-eligible for a WMM received a prescription for one. A State of the Art Conference on Weight Management workgroup, focused on pharmacotherapy, developed evidence-based recommendations and strategies to foster the appropriate use of WMM in the VHA. The workgroup identified patient, prescriber, and health system barriers to and facilitators for prescribing WMM...
March 7, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28264719/the-efficacy-of-the-modified-atkins-diet-in-north-sea-progressive-myoclonus-epilepsy-an-observational-prospective-open-label-study
#13
Martje E van Egmond, Amerins Weijenberg, Margreet E van Rijn, Jan Willem J Elting, Jeannette M Gelauff, Rodi Zutt, Deborah A Sival, Roald A Lambrechts, Marina A J Tijssen, Oebele F Brouwer, Tom J de Koning
BACKGROUND: North Sea Progressive Myoclonus Epilepsy is a rare and severe disorder caused by mutations in the GOSR2 gene. It is clinically characterized by progressive myoclonus, seizures, early-onset ataxia and areflexia. As in other progressive myoclonus epilepsies, the efficacy of antiepileptic drugs is disappointingly limited in North Sea Progressive Myoclonus Epilepsy. The ketogenic diet and the less restrictive modified Atkins diet have been proven to be effective in other drug-resistant epilepsy syndromes, including those with myoclonic seizures...
March 7, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28263384/mesothelium-expression-of-vascular-cell-adhesion-molecule-1-vcam-1-is-associated-with-an-unfavorable-prognosis-in-epithelial-ovarian-cancer-eoc
#14
Jennifer M Scalici, Sanja Arapovic, Erin J Saks, Kristen A Atkins, Gina Petroni, Linda R Duska, Jill K Slack-Davis
BACKGROUND: Mesothelium vascular cell adhesion molecule-1 (VCAM-1) expression in the metastatic epithelial ovarian cancer (EOC) microenvironment is induced by tumor and mediates tumor cell invasion. VCAM-1 imaging suggests expression during treatment is an indicator of platinum resistance. Here, we assess the potential prognostic significance of mesothelium VCAM-1 expression and prospectively evaluate whether soluble VCAM-1 (sVCAM-1) is a surrogate for mesothelium expression. METHODS: A retrospective review of EOC patients was performed to evaluate outcomes with mesothelium VCAM-1 expression determined by immunohistochemistry of peritoneum or omentum specimens...
May 15, 2017: Cancer
https://www.readbyqxmd.com/read/28260230/family-based-interventions-to-increase-physical-activity-in-children-a-systematic-review-meta-analysis-and-realist-synthesis
#15
H E Brown, A J Atkin, J Panter, G Wong, M J M Chinapaw, E M F van Sluijs
No abstract text is available yet for this article.
April 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28252839/implementation-evaluation-and-refinement-of-an-intervention-to-improve-blunt-chest-injury-management-a-mixed-methods-study
#16
Kate Curtis, Connie Van, Mary Lam, Stephen Asha, Annalise Unsworth, Alana Clements, Louise Atkins
AIMS AND OBJECTIVES: To investigate uptake of a Chest Injury Protocol (ChIP), examine factors influencing its implementation and identify interventions for promoting its use. BACKGROUND: Failure to treat blunt chest injuries in a timely manner with sufficient analgesia, physiotherapy and respiratory support, can lead to complications such as pneumonia and respiratory failure and/or death. DESIGN: This is a mixed methods implementation evaluation study...
March 2, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28245734/understanding-length-of-stay-following-spinal-cord-injury-insights-and-limitations-from-the-access-to-care-and-timing-act-project
#17
Anthony Scott Burns, Argelio Santos, Christiana L Cheng, Elaine Chan, Nader Fallah, Derek Atkins, Marcel F Dvorak, Chester Ho, Henry Ahn, Jérôme Paquet, Brian K Kwon, Vanessa Noonan
Costs associated with initial hospitalization following spinal cord injury (SCI) are substantial, and a major driver of costs is the length of stay (LOS) the injured individual remains hospitalized prior to community reintegration. Our aim was to study the factors and variables that contribute to LOS following traumatic SCI. Modeling (process mapping of the SCI healthcare delivery system in Canada and discrete event simulation) and regression analysis using a national registry of individuals with acute traumatic SCI in Canada, existing databases and peer-reviewed literature were used to examine the driver of LOS following traumatic SCI...
February 28, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28242923/control-of-browning-of-minimally-processed-mangoes-subjected-to-ultraviolet-radiation-pulses
#18
Aline Ellen Duarte de Sousa, Kelem Silva Fonseca, Wilny Karen da Silva Gomes, Ana Priscila Monteiro da Silva, Ebenézer de Oliveira Silva, Rolf Puschmann
The pulsed ultraviolet radiation (UVP) has been used as an alternative strategy for the control of microorganisms in food. However, its application causes the browning of minimally processed fruits and vegetables. In order to control the browning of the 'Tommy Atkins' minimally processed mango and treated with UVP (5.7 J cm(-2)) it was used 1-methylcyclopropene (1-MCP) (0.5 μL L(-1)), an ethylene action blocker in separate stages, comprising five treatments: control, UVP (U), 1-MCP + UVP (M + U), UVP + 1-MCP (U + M) e 1-MCP + UVP + 1-MCP (M + U + M)...
January 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28241926/combination-pills-for-treatment-of-high-blood-pressure-cost-effectiveness-in-the-asia-pacific-region
#19
EDITORIAL
Emily R Atkins, Thomas Lung, Julie Redfern
No abstract text is available yet for this article.
April 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28241268/long-term-outcomes-after-autologous-hematopoietic-stem-cell-transplantation-for-multiple-sclerosis
#20
Paolo A Muraro, Marcelo Pasquini, Harold L Atkins, James D Bowen, Dominique Farge, Athanasios Fassas, Mark S Freedman, George E Georges, Francesca Gualandi, Nelson Hamerschlak, Eva Havrdova, Vassilios K Kimiskidis, Tomas Kozak, Giovanni L Mancardi, Luca Massacesi, Daniela A Moraes, Richard A Nash, Steven Pavletic, Jian Ouyang, Montserrat Rovira, Albert Saiz, Belinda Simoes, Marek Trnený, Lin Zhu, Manuela Badoglio, Xiaobo Zhong, Maria Pia Sormani, Riccardo Saccardi
Importance: Autologous hematopoietic stem cell transplantation (AHSCT) may be effective in aggressive forms of multiple sclerosis (MS) that fail to respond to standard therapies. Objective: To evaluate the long-term outcomes in patients who underwent AHSCT for the treatment of MS in a large multicenter cohort. Design, Setting, and Participants: Data were obtained in a multicenter, observational, retrospective cohort study. Eligibility criteria were receipt of AHSCT for the treatment of MS between January 1995 and December 2006 and the availability of a prespecified minimum data set comprising the disease subtype at baseline; the Expanded Disability Status Scale (EDSS) score at baseline; information on the administered conditioning regimen and graft manipulation; and at least 1 follow-up visit or report after transplant...
February 20, 2017: JAMA Neurology
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