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https://www.readbyqxmd.com/read/29217964/sit-down-and-play-a-preventive-primary-care-based-program-to-enhance-parenting-practices
#1
Reshma Shah, Daniela DeFrino, Yoonsang Kim, Marc Atkins
The primary care office offers an ideal setting to encourage parenting behaviors that promote early childhood development. We conducted a pilot study to establish feasibility and acceptability of Sit Down and Play (SDP), a brief primary care-based program to facilitate positive parenting behaviors through take-home play activities. A prospective 1-month study was conducted in an urban primary care clinic. SDP was administered to 30 caregivers of 6-12 month old children while they waited for their well-child appointment...
February 2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/29211741/an-economic-evaluation-of-alexander-technique-lessons-or-acupuncture-sessions-for-patients-with-chronic-neck-pain-a-randomized-trial-atlas
#2
Holly Essex, Steve Parrott, Karl Atkin, Kathleen Ballard, Martin Bland, Janet Eldred, Catherine Hewitt, Ann Hopton, Ada Keding, Harriet Lansdown, Stewart Richmond, Helen Tilbrook, David Torgerson, Ian Watt, Aniela Wenham, Julia Woodman, Hugh MacPherson
OBJECTIVES: To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. METHODS: An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ)...
2017: PloS One
https://www.readbyqxmd.com/read/29208618/feasibility-study-of-a-randomised-controlled-trial-to-investigate-the-treatment-of-sarcoidosis-associated-fatigue-with-methylphenidate-fast-mp-a-study-protocol
#3
Christopher Atkins, Richard Fordham, Allan B Clark, Andrea Stockl, Andrew P Jones, Andrew M Wilson
INTRODUCTION: Fatigue is a frequent and troublesome manifestation of chronic sarcoidosis. This symptom can be debilitating and difficult to treat, with poor response to the treatment. Symptomatic management with neurostimulants, such as methylphenidate, is a possible treatment option. The use of such treatment strategies is not without precedent and has been trialled in cancer-related fatigue. Their use in sarcoidosis requires further evaluation before it can be recommended for clinical practice...
December 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/29206695/drug-induced-sleep-endoscopy-from-obscure-technique-to-diagnostic-tool-for-assessment-of-obstructive-sleep-apnea-for-surgical-interventions
#4
Joshua H Atkins, Jeff E Mandel
PURPOSE OF REVIEW: Provide a practical update on drug-induced sleep endoscopy (DISE) for anesthesia providers, which can also serve as a reference for those preparing to establish a DISE program. RECENT FINDINGS: New developments in surgical approaches to OSA and the growing global incidence of the condition have stimulated increased interest and demand for drug-induced sleep endoscopy. New techniques include transoral robotic surgery and hypoglossal nerve stimulation...
December 4, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29206297/dickkopf-homolog-3-dkk3-a-candidate-for-detection-and-treatment-of-cancers
#5
REVIEW
Leila Hamzehzadeh, Michele Caraglia, Stephen L Atkin, Amirhossein Sahebkar
Wnt signaling is an evolutionary highly conserved pathway that is modulated by several inhibitors and activators, and plays a key role in numerous physiological processes. One of the extracellular Wnt inhibitors is the DKK (Dickkopf Homolog) family which has four members (Dkk1-4) and a unique Dkk3-related gene, Dkkl1 (soggy). DKK3 is a divergent member of the DKK protein family. Evidence suggests that DKK3 may serve as a potential therapeutic target in several types of human cancers. We review here the biological role of DKK3 as a tumor suppressor gene (TSG) or oncogene, and its correlation with various miRNAs...
December 5, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29205283/clinician-factors-associated-with-prescribing-nicotine-replacement-therapy-in-pregnancy-a-cross-sectional-survey-of-australian-obstetricians-and-general-practitioners
#6
Yael Bar-Zeev, Billie Bonevski, Maree Gruppetta, Laura Twyman, Lou Atkins, Kerrin Palazzi, Christopher Oldmeadow, Gillian S Gould
The use of nicotine replacement therapy in pregnancy has been debated but evidence suggests that it is safer than smoking. A cross-sectional survey was conducted with: (i) general practitioners and obstetricians from a college database; and (ii) general practitioners with a special interest in Indigenous health. General practitioners had higher odds of prescribing compared to obstetricians. Reading guidelines, confidence, viewing nicotine replacement therapy as safe, effective and with good adherence, also significantly increased the odds of prescription...
December 4, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29203863/orai-channels-are-critical-for-receptor-mediated-endocytosis-of-albumin
#7
Bo Zeng, Gui-Lan Chen, Eliana Garcia-Vaz, Sunil Bhandari, Nikoleta Daskoulidou, Lisa M Berglund, Hongni Jiang, Thomas Hallett, Lu-Ping Zhou, Li Huang, Zi-Hao Xu, Viji Nair, Robert G Nelson, Wenjun Ju, Matthias Kretzler, Stephen L Atkin, Maria F Gomez, Shang-Zhong Xu
Impaired albumin reabsorption by proximal tubular epithelial cells (PTECs) has been highlighted in diabetic nephropathy (DN), but little is known about the underlying molecular mechanisms. Here we find that ORAI1-3, are preferentially expressed in PTECs and downregulated in patients with DN. Hyperglycemia or blockade of insulin signaling reduces the expression of ORAI1-3. Inhibition of ORAI channels by BTP2 and diethylstilbestrol or silencing of ORAI expression impairs albumin uptake. Transgenic mice expressing a dominant-negative Orai1 mutant (E108Q) increases albuminuria, and in vivo injection of BTP2 exacerbates albuminuria in streptozotocin-induced and Akita diabetic mice...
December 4, 2017: Nature Communications
https://www.readbyqxmd.com/read/29200408/angiotensin-converting-enzyme-activity-in-cavalier-king-charles-spaniels-with-an-ace-gene-polymorphism-and-myxomatous-mitral-valve-disease
#8
Kathryn M Meurs, Lisbeth H Olsen, Maria J Reimann, Bruce W Keene, Clarke E Atkins, Darcy Adin, Brent Aona, Julia Condit, Teresa DeFrancesco, Yamir Reina-Doreste, Joshua A Stern, Sandra Tou, Jessica Ward, Kathleen Woodruff
OBJECTIVES: Myxomatous mitral valve disease (MMVD) is the most common heart disease in the dog. It is particularly common in the Cavalier King Charles Spaniel (CKCS) breed and affected dogs are frequently managed with angiotensin-converting enzyme inhibitors (ACE-I). We have previously identified a canine ACE gene polymorphism associated with a decrease in angiotensin-converting enzyme (ACE) activity. The aim of this study was to evaluate for the prevalence of the ACE polymorphism in CKCS with mitral valve disease and to determine whether the presence of the polymorphism is associated with alterations in ACE activity at different stages of cardiac disease...
December 1, 2017: Pharmacogenetics and Genomics
https://www.readbyqxmd.com/read/29196525/mapping-local-and-global-variability-in-plant-trait-distributions
#9
Ethan E Butler, Abhirup Datta, Habacuc Flores-Moreno, Ming Chen, Kirk R Wythers, Farideh Fazayeli, Arindam Banerjee, Owen K Atkin, Jens Kattge, Bernard Amiaud, Benjamin Blonder, Gerhard Boenisch, Ben Bond-Lamberty, Kerry A Brown, Chaeho Byun, Giandiego Campetella, Bruno E L Cerabolini, Johannes H C Cornelissen, Joseph M Craine, Dylan Craven, Franciska T de Vries, Sandra Díaz, Tomas F Domingues, Estelle Forey, Andrés González-Melo, Nicolas Gross, Wenxuan Han, Wesley N Hattingh, Thomas Hickler, Steven Jansen, Koen Kramer, Nathan J B Kraft, Hiroko Kurokawa, Daniel C Laughlin, Patrick Meir, Vanessa Minden, Ülo Niinemets, Yusuke Onoda, Josep Peñuelas, Quentin Read, Lawren Sack, Brandon Schamp, Nadejda A Soudzilovskaia, Marko J Spasojevic, Enio Sosinski, Peter E Thornton, Fernando Valladares, Peter M van Bodegom, Mathew Williams, Christian Wirth, Peter B Reich
Our ability to understand and predict the response of ecosystems to a changing environment depends on quantifying vegetation functional diversity. However, representing this diversity at the global scale is challenging. Typically, in Earth system models, characterization of plant diversity has been limited to grouping related species into plant functional types (PFTs), with all trait variation in a PFT collapsed into a single mean value that is applied globally. Using the largest global plant trait database and state of the art Bayesian modeling, we created fine-grained global maps of plant trait distributions that can be applied to Earth system models...
December 1, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29195591/variability-in-motivational-interviewing-adherence-across-sessions-providers-sites-and-research-contexts
#10
Kevin A Hallgren, Aaron Dembe, Brian T Pace, Zac E Imel, Christine M Lee, David C Atkins
Providers' adherence in the delivery of behavioral interventions for substance use disorders is not fixed, but instead can vary across sessions, providers, and intervention sites. This variability can substantially impact the quality of intervention that clients receive. However, there has been limited work to systematically evaluate the extent to which substance use intervention adherence varies from session-to-session, provider-to-provider, and site-to-site. The present study quantifies the extent to which adherence to Motivational Interviewing (MI) for alcohol and drug use varies across sessions, providers, and intervention sites and compares the extent of this variability across three common MI research contexts that evaluate MI efficacy, MI effectiveness, and MI training...
January 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29188846/structure-and-dynamics-of-ionic-liquids-general-discussion
#11
Matthew Addicoat, Rob Atkin, José Nuno Canongia Lopes, Margarida Costa Gomes, Millicent Firestone, Ramesh Gardas, Simon Halstead, Christopher Hardacre, Laurence J Hardwick, John Holbrey, Patricia Hunt, Vladislav Ivaništšev, Johan Jacquemin, Robert Jones, Barbara Kirchner, Ruth Lynden-Bell, Doug MacFarlane, Guy Marlair, Himani Medhi, Markus Mezger, Agílio Pádua, Isabel Pantenburg, Susan Perkin, Joshua E S J Reid, Mark Rutland, Satyen Saha, Karina Shimizu, John M Slattery, Malgorzata Swadźba-Kwaśny, Shraeddha Tiwari, Seiji Tsuzuki, Betul Uralcan, Adriaan van den Bruinhorst, Masayoshi Watanabe, James Wishart
No abstract text is available yet for this article.
November 30, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/29188026/is-temperature-an-important-variable-in-recovery-after-mild-traumatic-brain-injury
#12
REVIEW
Coleen M Atkins, Helen M Bramlett, W Dalton Dietrich
With nearly 42 million mild traumatic brain injuries (mTBIs) occurring worldwide every year, understanding the factors that may adversely influence recovery after mTBI is important for developing guidelines in mTBI management. Extensive clinical evidence exists documenting the detrimental effects of elevated temperature levels on recovery after moderate to severe TBI. However, whether elevated temperature alters recovery after mTBI or concussion is an active area of investigation. Individuals engaged in exercise and competitive sports regularly experience body and brain temperature increases to hyperthermic levels and these temperature increases are prolonged in hot and humid ambient environments...
2017: F1000Research
https://www.readbyqxmd.com/read/29185808/lipid-modifying-activity-of-curcuminoids-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
Luis E Simental-Mendía, Matteo Pirro, Antonio M Gotto, Maciej Banach, Stephen L Atkin, Muhammed Majeed, Amirhossein Sahebkar
OBJECTIVE: The aim of this systematic review and meta-analysis was to determine and clarify the impact of curcuminoids on serum lipid levels. METHODS: Randomized controlled trials (RCTs) investigating the effects of curcuminoids on plasma lipids were searched in PubMed-Medline, Scopus, Web of Science databases (from inception to April 3rd, 2017). A random-effects model and generic inverse variance method were used for quantitative data synthesis. Sensitivity analysis was conducted using the leave-one-out method...
November 29, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29185568/phase-behaviour-and-thermodynamics-general-discussion
#14
Andrew Abbott, Hiroshi Abe, Leigh Aldous, Rob Atkin, Magdalena Bendová, Matteo Busato, José Nuno Canongia Lopes, Margarida Costa Gomes, Benjamin Cross, Carin Dietz, Jeffrey Everts, Millicent Firestone, Ramesh Gardas, Matthieu Gras, Tamar Greaves, Simon Halstead, Christopher Hardacre, Jason Harper, John Holbrey, Johan Jacquemin, Philip Jessop, Doug MacFarlane, Florian Maier, Himani Medhi, Markus Mezger, Agílio Pádua, Susan Perkin, Joshua E S J Reid, Satyen Saha, John M Slattery, Morgan L Thomas, Shraeddha Tiwari, Seiji Tsuzuki, Betul Uralcan, Masayoshi Watanabe, James Wishart, Tristan Youngs
No abstract text is available yet for this article.
November 29, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/29183532/descriptive-analysis-of-venous-thromboembolism-in-georgia-trauma-centers-compared-with-national-trauma-centers-participating-in-the-trauma-quality-improvement-program
#15
Randi L Lassiter, Dennis W Ashley, Regina S Medeiros, Bao-Ling Adam, Elizabeth G NeSmith, Tracy J Johns, Elizabeth V Atkins, Christopher J Dente, Colville H Ferdinand
This study was designed to compare the incidence of venous thromboembolism (VTE) in Georgia trauma centers with other national trauma centers participating in the Trauma Quality Improvement Program (TQIP). The use of chemoprophylaxis and characteristics of patients who developed VTE were also examined. We conducted a retrospective observational study of 325,703 trauma admissions to 245 trauma centers from 2013 to 2014. Patient demographics, rate of VTE, as well as the use, type, and timing of chemoprophylaxis were compared between patients admitted to Georgia and non-Georgia trauma centers...
November 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29182924/control-of-anthracnose-caused-by-colletotrichum-species-in-guava-mango-and-papaya-using-synergistic-combinations-of-chitosan-and-cymbopogon-citratus-d-c-ex-nees-stapf-essential-oil
#16
Priscila Dinah Lima Oliveira, Kataryne Árabe Rimá de Oliveira, Willie Anderson Dos Santos Vieira, Marcos Paz Saraiva Câmara, Evandro Leite de Souza
This study assessed the efficacy of chitosan (Chi) and Cymbopogon citratus (D.C. ex Nees) Stapf. essential oil (CCEO) combinations to control the mycelial growth of five pathogenic Colletotrichum species (C. asianum, C. siamense, C. fructicola, C. tropicale and C. karstii) in vitro, as well as the anthracnose development in guava (Psidium guajava L.) cv. Paluma, mango (Mangifera indica L.) cv. Tommy Atkins and papaya (Carica papaya L.) cv. Papaya artificially inoculated with these species. Combinations of Chi (2...
November 24, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29182884/four-lessons-learned-from-school-nurses-in-new-jersey-about-building-a-culture-of-health
#17
Robert Atkins
Building a Culture of Health will give all members of our society the opportunity to lead healthier lives. To achieve this aim, more stakeholders in the community-residents, elected officials, community-based nonprofits, law enforcement, and schools-need to be engaged in addressing the health challenges in our communities. Moreover, all community stakeholders have to think and act "upstream" by addressing the social determinants of health in their communities. Discussed in this article are some of the lessons that are being learned from the "upstream" actions of school nurses in New Jersey about building a Culture of Health...
November 1, 2017: NASN School Nurse
https://www.readbyqxmd.com/read/29181086/recent-advances-in-the-development-of-antiviral-therapeutics-for-rift-valley-fever-virus-infection
#18
REVIEW
Colm Atkins, Alexander N Freiberg
Rift Valley fever virus (RVFV) is a mosquito-borne bunyavirus endemic to sub-Saharan Africa and the Arabian Peninsula and the etiological agent of Rift Valley fever. Rift Valley fever is a disease of major public health and economic concern, affecting livestock and humans. In ruminants, RVFV infection is characterized by high mortality rates in newborns and near 100% abortion rates in pregnant animals. Infection in humans is typically manifested as a self-limiting febrile illness, but can lead to severe and fatal hepatitis, encephalitis, hemorrhagic fever or retinitis with partial or complete blindness...
November 2017: Future Virology
https://www.readbyqxmd.com/read/29173665/peripheral-nerve-radiofrequency-neurotomy-hip-and-knee-joints
#19
REVIEW
Liza Hernández-González, Carlos E Calvo, David Atkins-González
Intra-articular hip and knee pain is a common cause of physical and psychosocial disability. Many conservative treatment options provide only short-term relief. Recent research studies have shown improvement in pain and function with minimal complications after radiofrequency neurotomy of the hip and the knee, especially in patients who have failed conservative treatment or are not surgical candidates. More quality research studies are needed to establish the efficacy and safety of these procedures in patients with refractory hip and knee pain...
February 2018: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/29173639/escherichia-coli-and-cronobacter-sakazakii-in-tommy-atkins-minimally-processed-mangos-survival-growth-and-effect-of-uv-c-and-electrolyzed-water
#20
David Santo, Ana Graça, Carla Nunes, Célia Quintas
These studies were aimed at assessing the growing capacity of Escherichia coli and Cronobacter sakazakii and the effectiveness of Ultraviolet-C (UV-C) radiation, acidic electrolyzed (AEW) and neutral electrolyzed (NEW) waters in the inhibition of these bacteria on minimally processed 'Tommy Atkins' mangoes (MPM). The fruits were contaminated by dip inoculation and kept 10 days at 4, 8, 12 and 20 °C while enumerating bacteria. Contaminated mangoes were disinfected using UV-C (2.5, 5, 7.5 and 10 kJ/m2), AEW, NEW and sodium hypochlorite (SH) and the microorganisms were monitored...
April 2018: Food Microbiology
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