monC

Fluorescent metal nanoclusters (MNCs) have found extensive application in recognizing molecular species. Here, orange-red fluorescent Arg-A. paniculata-MoNCs were synthesized using Andrographis paniculata leaf extract, arginine as a ligand, and MoCl5 as a metal precursor. The Arg-A. paniculata-MoNCs complex exhibited a quantum yield (QY) of 16.91% and excitation/emission wavelengths of 400/665 nm. The synthesized Arg-A. paniculata-MoNCs successfully acted as a probe for assaying neomycin sulphate (NS) via fluorescence turn-off and K+ ions via fluorescence turn-on mechanisms, respectively...

In this work, Cassia tora (C. tora) have been used as a template to synthesize green fluorescent C. tora molybdenum nanoclusters (C. tora-MoNCs) through a green chemistry approach. These C. tora-MoNCs showed a quantum yield (QY) of 7.72% and exhibited a significant emission peak at 498 nm when excited at 380 nm. The as-prepared C. tora-MoNCs had an average size of 3.48 ± 0.80 nm and showed different surface functionality. The as-synthesized C. tora-MoNCs were successfully identified the hydroxyl radical (• OH) via a fluorescence quenching mechanism...

The fabrication of stable fluorescent MoNCs in aqueous media is quite challenging as it is not much explored yet. Herein, we report a facile and efficient strategy for assembling MoNCs using 2,3 dialdehyde maltose-cysteine Schiff base (DAM-cysteine) as a ligand for detecting myoglobin and γ-aminobutyric acid (GABA) in biofluids with high selectivity and sensitivity. The DAM-cysteine-MoNCs displayed fluorescence of bright blue color under a UV light at 365 nm with peak of emission at 444 nm after exciting at 370 nm...

ConspectusCompositing MOFs with polymers brings out the best properties of both worlds. The solubility and excellent mechanical properties of polymers endow the brittle, powdery MOFs with enhanced processability, thereby enriching their functions as solid sorbents, filters, membranes, catalysts, drug delivery vehicles, and so forth. While most MOF-polymer composites are random mixtures of two materials with little control over their fine structures, MOF@polymer core-shell particles have recently emerged as a new platform for precise composite design...

Electrocatalytic nitrogen reduction reaction (eNRR) is a promising method for the sustainable production of ammonia as an alternative to the traditional energy-intensive Haber-Bosch process. In this work, an efficient strategy by atomic spin regulation to promote NRR through Fe-transition metal (TM) hybrid heteronuclear dual-atom catalysts has been studied. By means of DFT computations, the stability, activity, and selectivity of 30 kinds of Fe-based dual-atoms anchored on N-doped porous graphene are systematically investigated to evaluate their catalytic performance...

It is important to reduce the danger of collecting flame image data sets by compositing flame images by computer. In this paper, a Global-Local mask Generative Adversarial Network (FGL-GAN) is proposed to address the current status of low quality composite flame images. First, FGL-GAN adopts a hierarchical Global-Local generator structure, to locally render high-quality flame halo and reflection, while also maintaining a consistent global style. Second, FGL-GAN incorporates the fire mask as part of the input of the generation module, which improves the rendering quality of flame halo and reflection...

In this work, terephthaldehyde-cysteine-molybdenum nanoclusters (TPA-Cys-MoNCs) were synthesized by using terephthaldehyde-cysteine (TPA-Cys) Schiff base as a novel ligand. The as-synthesized TPA-Cys-MoNCs showed blue fluorescence under UV lamp at 365 nm, displaying emission peak at 455 nm when excited at 340 nm. The fluorescent TPA-Cys-MoNCs are used as a probe for sensitive assay of pyrophosphate (PPi) via fluorescence quenching mechanism. The emission peak intensity of TPA-Cys-MoNCs at 455 nm exhibited a linear quenching with increasing amount of PPi...

The reduction of healthcare-associated infections (HAIs) is one of the most important issues in the healthcare context for every type of hospital. In three operational units of the Scientific Clinical Institutes Maugeri SpA SB, a rehabilitation hospital in Cassano delle Murge (Italy), some corrective measures were introduced in 2017 to reduce the occurrence of HAIs. Lean Six Sigma was used together with the Define, Measure, Analyze, Improve, Control (DMAIC) roadmap to analyze both the impact of such measures on HAIs and the length of hospital stay (LOS) in the Rehabilitative Cardiology, Rehabilitative Neurology, Functional Recovery and Rehabilitation units in the Medical Center for Intensive Rehabilitation...

In this study, the aim was to explore the effectiveness of the UV/H2 O2 photolysis (UVP) process in terms of antimicrobial activity reduction and increasing the mean oxidation number of carbon (MONC) under the degradation of chloramphenicol (CHPL) drug. CHPL degradation kinetics and the effects of foreign anions on CHPL degradation were explored in this study. The order of the inhibition effect was found as Cl- > NO3 - > HCO3 - due to their different in HO• radical scavenging capacity. A pseudo-first-order model for CHPL degradation was well established, and the rate constant (kobs ) was 2...

BACKGROUND: Emerging evidence shows that abnormal expression of long non-coding RNA is involved in the occurrence and development of various tumors. LncRNA MONC is abnormally expressed in head and neck squamous cell carcinoma, lung cancer, colorectal cancer, and acute megakaryocytic leukemia, but the biological function and potential regulatory mechanism of MONC in endometrial cancer stem cells (ECSCs) and endometrial cancer cells (ECCs) have not been studied. In this study, we aimed to explore the tumor suppressive effect and mechanism of MONC in regulating ECSCs and ECCs...

Polymeric metal-organic nanocapsule networks (polyMONCs), where metal-organic nanocapsules (MONCs) are connected by functional polymers, could possess the properties of traditional polymers and also retain the structures of MONCs. Herein we constructed novel polyMONCs based on Mg-seamed pyrogallol[4]arene-containing MONCs through supramolecular coordination-driven self-assembly. The MONCs can be successfully polymerized by using polyethylene glycol as linkers and the prepared polyMONCs can be further made into gels with self-healing property and stimuli-responsiveness...

Herein, we report machine learning algorithms by training datasets from a set of both succeeded and failed experiments for studying the crystallization propensity of metal-organic nanocapsules (MONCs). Among a variety of studied machine learning algorithms, XGBoost affords the highest prediction accuracy of > 90%. The derived chemical feature scores that determine importance of reaction parameters from the XGBoost model assist to identify synthesis parameters for successfully synthesizing new hierarchical structures of MONCs, showing superior performance to a well-trained chemist...

Design and synthesis of Pt-based nanocrystals with controlled structural diversity and complexity can potentially bring about multifunctional properties. In this work, we present a facile two-step strategy for the construction of the PtPdRh mesoporous octahedral nanocages (PtPdRh MONCs). This unique nanoarchitectonics rationally integrates multiple advantages (i.e., the octahedral shape, hollow cavity and mesoporous surface) into one catalyst, which facilitates the efficient utilization of noble metal atoms at both of the interior and exterior surfaces...

The aim of this study was to characterize daily fluctuations in postural control, gait and plantar cutaneous sensitivity in institutionalized older adults. Twenty-five older adults (>85 years old) living in a nursing home were recruited. Postural, gait and plantar cutaneous sensitivity parameters were collected at the following times: 8:00, 11:00, 14:00 and 17:00. Statistics were first calculated with the data from the whole group of the participants. A hierarchical cluster analysis was performed as a second step in order to determine if there was more than one pattern in the daily fluctuations of gait, postural control and plantar cutaneous sensitivity...

We introduce for first time a facile protocol for the rapid synthesis of a molybdenum nanoclusters (MoNCs) at room temperature using thiolated dithiothreitol (DTT) as capping agents. The initial fluorescence from the MoNCs is observed in 30 min and further intensified in 48 h. The mean diameter of nanoclusters was found to be 1.5 nm with -77 mV zeta potential. The nanoclusters have good stability in all tested pH ranges, especially between pH 7 and 10. This property makes the nanomaterial to be ideal for many types of possible biological/biomedicine applications such as drug delivery or biological imaging...

Under suitable conditions, C-alkylpyrogallol[4]arenes (PgCs) arrange into spherical metal-organic nanocapsules (MONCs) upon coordination to appropriate metal ions. Herein we present the synthesis and structural characterization of a novel FeII /FeIII -seamed MONC, as well as studies related to its electrochemical and magnetic behaviors. Unlike other MONCs that are assembled through 24 metal ions, this nanocapsule comprises 32 Fe ions, uncovering 8 additional coordination sites situated between the constituent PgC subunits...

Tumor microenvironment-induced ultrasmall nanodrug generation (TMIUSNG) is an unprecedented approach to overcome the drug penetration barriers across complex biological systems, poor circulation stability and limited drug loading efficiency (DLE). Herein, a novel strategy was designed to synthesize metal-organic nanodrug complexes (MONCs) through supramolecular coassembly of photosensitizer sinoporphyrin sodium, chemotherapeutic drug doxorubicin and ferric ions. Compared with the free photosensitizer, MONCs produced 3-fold more reactive oxygen species (ROS) through the energy transfer-mediated fluorescence quenching...

Two structurally analogous Mn-seamed C-alkylpyrogallol[4]arene (PgC n )-based metal-organic nanocapsules (MONCs) have been synthesized under similar reaction conditions and characterized by crystallographic, electrochemical, and magnetic susceptibility techniques. Both MONCs contain 24 Mn centers, but, somewhat surprisingly, marked differences in oxidation state distribution are observed upon analysis. One MONC contains exclusively MnII ions, while the other is a mixed-valence MnII / MnIII assembly. We propose that these disparate oxidation state distributions arise from slight differences in pH achieved during synthesis, a factor that may lead to many spectacular new MONCs (and associated host-guest chemistries)...

C-alkylpyrogallol[4]arenes (PgCs) have been studied for their ability to form metal-organic nanocapsules (MONCs) through coordination to appropriate metal ions. Here we present the synthesis and characterization of an MnII /MnIII -seamed MONC in addition to its electrochemical and magnetic behavior. This MONC assembles from 24 manganese ions and 6 PgCs, while an additional metal ion is located on the capsule interior, anchored through the introduction of bridging nitrite ions. The latter originate from an in situ redox reaction that occurs during the self-assembly process, thus representing a new route to otherwise unobtainable nanocapsules...

Novel supramolecular nanocapsules based on metal-directed assembly have captured tremendous interest due to their applications in fields such as catalysis, selective gas adsorption, and biomedicine. Functionalization of metal-organic nanocapsules (MONCs) by using organic ligands with different pendant groups affords more complexity to the structure and may lead to novel properties. In this work, we report the solvothermal synthesis of a group of magnesium-based MONCs using C-alkylpyrogallol[4]arenes with varying alkyl chain lengths...