Y Vivian Tsai, P Brandon Bookstaver, Joseph Kohn, Julie Ann Justo, Darrell Childress, Stefanie Stramel, Douglas Slain, Patrick Tu, Mary Joyce B Wingler, Bruce M Jones, Daniel T Anderson, Megan M Seddon, David A Cretella, Joshua Eudy, Hana Winders, Kayla Antosz, Pamela Bailey, Majdi N Al-Hasan
OBJECTIVE: To evaluate temporal trends in the prevalence of gram-negative bacteria (GNB) with difficult-to-treat resistance (DTR) in the southeastern United States. Secondary objective was to examine the use of novel β-lactams for GNB with DTR by both antimicrobial use (AU) and a novel metric of adjusted AU by microbiological burden (am-AU). DESIGN: Retrospective, multicenter, cohort. SETTING: Ten hospitals in the southeastern United States...
2024: Antimicrob Steward Healthc Epidemiol