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psychopharmacological treatment of anxiety

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https://www.readbyqxmd.com/read/30152283/psychopharmacotherapy-of-obsessive-compulsive-symptoms-within-the-framework-of-tourette-syndrome
#1
Aribert Rothenberger, Veit Roessner
While Behavioral Therapy (BT) should be recommended as the first step in the treatment of OCD as well as TS, medication can be added for augmentation and in certain situations (e.g. family preference, BT not available or feasible) the priority may even reverse. This narrative review is given on the complexity of drug treatment in patients comorbid for obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) and other tic problems. OCD with TS is a co-occuring combination of two generally delimitable, but in detail also overlapping disorders which wax and wane with time but have different courses and necessities and options of treatment...
August 27, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/30123505/treatment-of-children-and-adolescents-with-avoidant-restrictive-food-intake-disorder-a-case-series-examining-the-feasibility-of-family-therapy-and-adjunctive-treatments
#2
Wendy Spettigue, Mark L Norris, Alexandre Santos, Nicole Obeid
Background: To date, little research has examined the effectiveness of either modified Family-Based Therapy or psychopharmacological treatments for patients diagnosed with avoidant/restrictive food intake disorder (ARFID), and there is little evidence to guide clinicians treating children and adolescents with ARFID. This case series describes the clinical presentations, treatments and outcomes of six patient diagnosed with ARFID who were treated sequentially by a child psychiatrist and adolescent medicine physician in a hospital-based eating disorder program...
2018: Journal of Eating Disorders
https://www.readbyqxmd.com/read/30056792/pharmacotherapy-for-generalized-anxiety-disorder-in-adult-and-pediatric-patients-an-evidence-based-treatment-review
#3
REVIEW
Jeffrey R Strawn, Laura Geracioti, Neil Rajdev, Kelly Clemenza, Amir Levine
Generalized anxiety disorder (GAD) often begins during adolescence or early adulthood and persists throughout the lifespan. Randomized controlled trials support the efficacy of selective serotonin and selective serotonin norepinephrine reuptake inhibitors (SSRIs and SNRIs, respectively), as well as benzodiazepines, azapirones, anti-adrenergic medications, melatonin analogs, second-generation antipsychotics, kava, and lavender oil in GAD. However, psychopharmacologic treatment selection requires clinicians to consider multiple factors, including age, co-morbidity, and prior treatment...
July 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/30036387/salivary-testosterone-in-relation-to-social-cognition-and-social-anxiety-in-children-and-adolescents-with-47-xxy-klinefelter-syndrome
#4
Sophie van Rijn
BACKGROUND: Approximately 1 in 650 boys are born with an extra X chromosome. Boys and men with 47,XXY (Klinefelter syndrome) are at risk for neurodevelopmental disorders and specific cognitive impairments. This study was focused on social anxiety and social cognition. The aim was to assess if these aspects of the phenotype are related to testosterone deficiency, which is typically seen in 47,XXY from puberty onwards. METHODS: In the study 20 boys with 47,XXY and 25 non-clinical controls between 8 and 19 years participated...
2018: PloS One
https://www.readbyqxmd.com/read/30018020/psychopharmacology-in-transplantation-medicine
#5
REVIEW
Kai G Kahl, Gabriel Eckermann, Helge Frieling, Thomas Hillemacher
Organ transplantation has become a well-established treatment option in patients with end-stage organ diseases. Although quality of life has markedly improved, psychiatric disorders before and after transplantation are more frequent compared to the general population. Psychopharmacological treatment is recommended for almost all mental disorders according to current guidelines, but may pose particular problems in organ transplant patients. Changes in the metabolism and elimination of drugs during organ insufficiency, drug interactions, and overlapping side effects between psychopharmacological and immunosuppressive drugs are challenging problems in clinical management...
January 10, 2019: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29956326/psychopharmacological-effects-and-safety-of-styryl-2-pyrones-and-dihydrostyryl-2-pyrones-rich-fraction-from-polygala-sabulosa-absence-of-withdrawal-syndrome-and-tolerance-to-anxiolytic-like-and-anticonvulsant-effects
#6
Filipe Silveira Duarte, Marcelo Duzzioni, Rafael Luiz Prim, Alcíbia Maia Cardozo, Claudia Regina Dos Santos, Maria Goretti da Silva, Maria Beatriz Cacese Shiozawa, Beatriz Garcia Mendes, Tiago Tizziani, Inês Maria Costa Brighente, Moacir Geraldo Pizzolatti, Thereza Christina Monteiro de Lima
OBJECTIVES: To investigate whether mice develop tolerance to the anxiolytic-like and anticonvulsant effects of subchronic treatment with EA (the styryl-2-pyrones and dihydrostyryl-2-pyrones-rich fraction of Polygala sabulosa), as well as any withdrawal symptoms after abrupt discontinuation; to compare the effects of EA with those of diazepam (DZP) on withdrawal-induced anxiety; and to evaluate the toxicity of EA according to OECD guidelines. METHODS: Male or female mice were acutely or subchronically treated with EA or DZP, and their tolerance to anxiolytic (evaluated in the elevated plus maze, EPM) and anticonvulsant effects (measured against pentylenetetrazole (PTZ)-induced convulsions) were investigated...
September 2018: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/29935979/treatment-of-depression-anxiety-and-trauma-related-disorders-during-the-perinatal-period-a-systematic-review
#7
REVIEW
Yael I Nillni, Aydan Mehralizade, Laura Mayer, Snezana Milanovic
Women with psychiatric disorders during pregnancy and the postpartum period (i.e., perinatal period) are at increased risk for adverse maternal and child outcomes. Effective treatment of psychiatric disorders during the perinatal period is imperative. This review summarizes the outcomes of 78 studies focused on the treatment of depression, anxiety, and trauma-related disorders during the perinatal period. The majority of studies focused on perinatal depression (n = 73). Of the five studies focused on anxiety or trauma-related disorders, only one was a randomized controlled trial (RCT)...
June 9, 2018: Clinical Psychology Review
https://www.readbyqxmd.com/read/29898196/pituitary-gland-volumes-in-patients-with-obsessive-compulsive-disorder-before-and-after-cognitive-behavioral-therapy
#8
Murad Atmaca, Hanefi Yildirim, Seda Yilmaz, Neslihan Caglar, Sema Baykara, Yasemin Kekilli, Filiz Koseoglu, Hakan Turkcapar
OBJECTIVE: The beneficial effects of psychopharmacological and cognitive behavioral therapy (CBT) on the brain are not well understood. In a previous study, we found smaller pituitary volumes in patients with obsessive-compulsive disorder (OCD). The purpose of this study was to examine the effect of CBT on pituitary gland volume. METHODS: A total of 81 patients with various anxiety disorders and the same number of healthy controls underwent magnetic resonance imaging, and their pituitary gland volumes were compared at baseline...
October 2018: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/29863389/-initiation-and-retention-in-couples-outpatient-treatment-for-parents-with-drug-and-alcohol-use-disorders-correction
#9
(no author information available yet)
Reports an error in "Initiation and retention in couples outpatient treatment for parents with drug and alcohol use disorders" by Abby L. Braitman and Michelle L. Kelley ( Experimental and Clinical Psychopharmacology , 2016[Jun], Vol 24[3], 174-184). In the article, there are errors in Table 2. In the corrected table, the impact of Men's perpetration of violence changes from a non-significant trend (p < .10) to a significant effect (p < .05). Also within Table 2, Women's dyadic cohesion effect changed from a significant finding to a non-significant trend (p ...
June 2018: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29858643/-homeopathy-for-psychiatric-patients-for-and-against
#10
REVIEW
N Hock, G Juckel
The application of homeopathic treatment quickly becomes a matter of ideological confrontation; however, homeopathy is steadily gaining in sympathy in the population. Although the possible effectiveness and the modes of action are currently not scientifically elucidated and the study situation regarding homeopathic treatment in psychiatry is still manageable, there is a whole series of positive evidence for the effects of homeopathic remedies for mental disorders, such as depression, anxiety disorders and addiction...
September 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29803818/perinatal-anxiety-approach-to-diagnosis-and-management-in-the-obstetric-setting
#11
REVIEW
Katie R Thorsness, Corey Watson, Elizabeth M LaRusso
Anxiety is common in women during the perinatal period, manifests with various symptoms and severity, and is associated with significant maternal morbidity and adverse obstetric and neonatal outcomes. Given the intimate relationship and frequency of contact, the obstetric provider is positioned optimally to create a therapeutic alliance and to treat perinatal anxiety. Time constraints, absence of randomized controlled trials, mixed quality of data, and concern for potential adverse reproductive outcomes all limit the clinician's ability to initiate informed risk-benefit discussions...
October 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29744988/behavioral-health-care-in-solid-organ-transplantation-in-a-pediatric-setting
#12
Katharine Thomson, Kristine McKenna, Katherine Bedard-Thomas, Melisa Oliva, Patricia Ibeziako
This study examined the demographic, medical, and psychiatric characteristics of transplant patients across organ groups seen by transplant psychology/psychiatry clinicians at a pediatric institution between 2008 and 2014. Chart reviews were conducted to better understand the behavioral health care provided to SOT patients and the role of transplant-dedicated psychology and psychiatry clinicians. Transplant psychology/psychiatry was consulted a total of 1060 times on 399 unique SOT patients over a 6-year period...
August 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29730844/benzodiazepine-ingestion-as-a-way-to-die-by-suicide-and-related-safety-the-case-of-an-elderly-patient
#13
Laura Cremaschi, Benedetta Grancini, Vera De Carlo, Sara Pozzoli, A Carlo Altamura, Bernardo Dell'Osso
Benzodiazepines (BDZs) are widespread psychotropic compounds, often prescribed as first-line symptomatic option by general practitioners in patients with different psychiatric disorders. Sometimes, however, they contribute to delay the administration of the first appropriate psychopharmacological treatment, thus leading to a longer duration of untreated illness in patients with depressive and anxiety disorders. The well-established pros of BDZs use in clinical practice include efficacy, rapidity of action, versatility, and safety...
May 5, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29675280/what-can-happen-when-postpartum-anxiety-progresses-to-psychosis-a-case-study
#14
Vesna Pirec
This case report describes a primipara without documented psychiatric history prior to complicated delivery. Onset of severe insomnia and anxiety was right after childbirth but not treated. Obsessive thinking pattern became more prominent. The patient became depressed and sought psychiatric help four months after delivery. Insomnia was then treated pharmacologically. Anxiety and depression persisted, suicidal ideation emerged, and the patient became confused, indecisive, overwhelmed, and delusional regarding her child's health...
2018: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/29644487/therapeutic-use-of-carbohydrate-restricted-diets-in-an-autistic-child-a-case-report-of-clinical-and-18fdg-pet-findings
#15
Iwona Żarnowska, Beata Chrapko, Grażyna Gwizda, Anna Nocuń, Krystyna Mitosek-Szewczyk, Maciej Gasior
The ketogenic diet (KD) is a high-fat, adequate-protein, and low-carbohydrate diet that has been used successfully in the treatment of refractory epilepsies for almost 100 years. There has been accumulating evidence to show that the KD may provide a therapeutic benefit in autism spectrum disorders, albeit by a yet-unknown mechanism. We report a case of a 6-year-old patient with high-functioning autism and subclinical epileptic discharges who responded poorly to several behavioural and psychopharmacological treatments...
August 2018: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29620793/antidepressants-versus-placebo-for-panic-disorder-in-adults
#16
REVIEW
Irene Bighelli, Mariasole Castellazzi, Andrea Cipriani, Francesca Girlanda, Giuseppe Guaiana, Markus Koesters, Giulia Turrini, Toshi A Furukawa, Corrado Barbui
BACKGROUND: Panic disorder is characterised by repeated, unexpected panic attacks, which represent a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes, and in which at least four of 13 characteristic symptoms are experienced, including racing heart, chest pain, sweating, shaking, dizziness, flushing, stomach churning, faintness and breathlessness. It is common in the general population with a lifetime prevalence of 1% to 4%. The treatment of panic disorder includes psychological and pharmacological interventions...
April 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29495298/transcranial-direct-current-stimulation-for-obsessive-compulsive-disorder-a-systematic-review
#17
REVIEW
Jérôme Brunelin, Marine Mondino, Rémy Bation, Ulrich Palm, Mohamed Saoud, Emmanuel Poulet
Despite the advances in psychopharmacology and established psychotherapeutic interventions, more than 40% of patients with obsessive-compulsive disorder (OCD) do not respond to conventional treatment approaches. Transcranial direct current stimulation (tDCS) has been recently proposed as a therapeutic tool to alleviate treatment-resistant symptoms in patients with OCD. The aim of this review was to provide a comprehensive overview of the current state of the art and future clinical applications of tDCS in patients with OCD...
February 24, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29482525/internet-based-grief-therapy-for-bereaved-individuals-after-loss-due-to-haematological-cancer-study-protocol-of-a-randomized-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Rahel Hoffmann, Julia Große, Michaela Nagl, Dietger Niederwieser, Anja Mehnert, Anette Kersting
BACKGROUND: Approximately 10% of the individuals experiencing the death of a loved one develop prolonged grief disorder (PGD) after bereavement. Family members of haematological cancer patients might be particularly burdened since their loss experience is preceded by a very strenuous time of disease and aggressive treatment. However, support needs of relatives of cancer patients often remain unmet, also after the death of the patient. Therapeutic possibilities are enhanced by providing easily available and accessible Internet-based therapies...
February 27, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29447060/treatment-of-selective-mutism-based-on-cognitive-behavioural-therapy-psychopharmacology-and-combination-therapy-a-systematic-review
#19
REVIEW
Kasper Rud Østergaard
BACKGROUND: Selective mutism (SM) is a debilitating childhood anxiety disorder characterized by a persistent lack of speech in certain social settings and is considered hard to treat. Cognitive behavioral therapy (CBT) and pharmacological treatments are the best described treatments in the literature. AIM: To test whether there is evidence on treatment based on CBT, medication or a combination of these. METHODS: Systematic and critical review of the literature on CBT and/or pharmacological treatments of SM...
May 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29392446/psychiatric-aspects-of-acute-porphyria-a-comprehensive-review
#20
REVIEW
Laura Duque-Serrano, Liliana Patarroyo-Rodriguez, Dorothy Gotlib, Juan C Molano-Eslava
PURPOSE OF REVIEW: The aim of this paper is to review psychiatric manifestations, comorbidities, and psychopharmacological management in individuals with acute porphyria (AP). RECENT FINDINGS: Recent literature begins to clarify associations between AP, schizophrenia, bipolar disorder, and other psychopathology. Broad psychiatric symptoms have been associated to acute porphyria (AP) and correspond to a spectrum of heterogeneous manifestations such as anxiety, affective alterations, behavioral changes, personality, and psychotic symptoms...
February 2, 2018: Current Psychiatry Reports
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