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https://www.readbyqxmd.com/read/28432894/the-structure-correlates-and-treatment-related-changes-of-mindfulness-facets-across-the-anxiety-disorders-and-obsessive-compulsive-disorder
#1
Lance L Hawley, Jenny Rogojanski, Valerie Vorstenbosch, Lena C Quilty, Judith M Laposa, Neil A Rector
Research with non-clinical and clinical samples has examined how mindfulness concepts relate to psychological symptom presentations. However, there is less clarity when examining treatment-seeking patients who experience DSM-diagnosed anxiety and obsessional disorders - both cross-sectionally, and following empirically-supported treatments. The Five Facet Mindfulness Questionnaire (FFMQ; Baer, Smith, Hopkins, Krietemeyer, & Toney, 2006) conceptualizes mindfulness as consisting of five facets: Observing, Describing, Acting with Awareness, Nonreactivity, and Nonjudging...
March 14, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28423066/influence-of-maternal-anxiety-on-child-anxiety-during-dental-care-cross-sectional-study
#2
Paloma Busato, Raíssa Rigo Garbín, Catielma Nascimento Santos, Luiz Renato Paranhos, Lilian Rigo
CONTEXT AND OBJECTIVES: Anxiety is usually classified as a disorder of neurotic nature and is often related to contexts of stress, which may include worries, motor tension and autonomic hyperactivity. The aim of this study was to assess the influence of mothers' anxiety on their children's anxiety during dental care. DESIGN AND SETTING: Analytical cross-sectional study conducted at in a private dentistry school in the south of Brazil. METHODS: Convenience sampling was used...
April 13, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28421682/predicting-abstinence-from-methamphetamine-use-after-residential-rehabilitation-findings-from-the-methamphetamine-treatment-evaluation-study
#3
Rebecca McKetin, Astrid Kothe, Amanda L Baker, Nicole K Lee, Joanne Ross, Dan I Lubman
INTRODUCTION AND AIMS: We previously found that residential rehabilitation increased continuous abstinence from methamphetamine use 1 year after treatment. We examine what client and treatment characteristics predict this outcome. DESIGN AND METHODS: Participants (n = 176) were dependent on methamphetamine and entering residential rehabilitation for methamphetamine use. Simultaneous logistic regression was used to identify independent predictors of continuous abstinence from methamphetamine use at 1 year follow-up...
April 18, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28418834/reduction-in-costs-after-treating-comorbid-panic-disorder-with-agoraphobia-and-generalized-anxiety-disorder
#4
Vedrana Ikic, Claude Belanger, Stephane Bouchard, Patrick Gosselin, Frederic Langlois, Joane Labrecque, Michel J Dugas, Andre Marchand
BACKGROUND: Panic disorder with agoraphobia (PDA) and generalized anxiety disorder (GAD) are impairing and costly disorders that are often misdiagnosed and left untreated despite multiple consultations. These disorders frequently co-occur, but little is known about the costs associated with their comorbidity and the impact of cognitive-behavioral therapy (CBT) on cost reduction. AIMS OF THE STUDY: The first objective of this study was to assess the mental health-related costs associated with the specific concomitance of PDA and GAD...
March 1, 2017: Journal of Mental Health Policy and Economics
https://www.readbyqxmd.com/read/28410461/gradients-of-fear-how-perception-influences-fear-generalization
#5
Dieter Struyf, Jonas Zaman, Dirk Hermans, Bram Vervliet
The current experiment investigated whether overgeneralization of fear could be due to an inability to perceptually discriminate the initial fear-evoking stimulus from similar stimuli, as fear learning-induced perceptual impairments have been reported but their influence on generalization gradients remain to be elucidated. Three hundred and sixty-eight healthy volunteers participated in a differential fear conditioning paradigm with circles of different sizes as conditioned stimuli (CS), of which one was paired to an aversive IAPS picture...
June 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28403387/skin-conductance-responses-and-neural-activations-during-fear-conditioning-and-extinction-recall-across-anxiety-disorders
#6
Marie-France Marin, Rachel G Zsido, Huijin Song, Natasha B Lasko, William D S Killgore, Scott L Rauch, Naomi M Simon, Mohammed R Milad
Importance: The fear conditioning and extinction neurocircuitry has been extensively studied in healthy and clinical populations, with a particular focus on posttraumatic stress disorder. Despite significant overlap of symptoms between posttraumatic stress disorder and anxiety disorders, the latter has received less attention. Given that dysregulated fear levels characterize anxiety disorders, examining the neural correlates of fear and extinction learning may shed light on the pathogenesis of underlying anxiety disorders...
April 12, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28401046/functional-neuroanatomy-in-panic-disorder-status-quo-of-the-research
#7
Thomas Sobanski, Gerd Wagner
AIM: To provide an overview of the current research in the functional neuroanatomy of panic disorder. METHODS: Panic disorder (PD) is a frequent psychiatric disease. Gorman et al (1989; 2000) proposed a comprehensive neuroanatomical model of PD, which suggested that fear- and anxiety-related responses are mediated by a so-called "fear network" which is centered in the amygdala and includes the hippocampus, thalamus, hypothalamus, periaqueductal gray region, locus coeruleus and other brainstem sites...
March 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/28400482/epigenetic-programming-of-the-neuroendocrine-stress-response-by-adult-life-stress
#8
Bart Dirven, Judith Homberg, Tamas Kozicz, Marloes Henckens
The hypothalamic-pituitary adrenal (HPA) axis is critically involved in the neuroendocrine regulation of stress adaptation, and the restoration of homeostasis following stress exposure. Dysregulation of this axis is associated with stress-related pathologies like major depressive disorder, post-traumatic stress disorder, panic disorder, and chronic anxiety. It has long been understood that stress during early life can have a significant lasting influence on the development of the neuroendocrine system and its neural regulators, partially by modifying epigenetic regulation of gene expression, with implications for health and well-being in later life...
April 11, 2017: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/28375724/panic-disorder-comorbidity-with-medical-conditions-and-treatment-implications
#9
Alicia E Meuret, Juliet Kroll, Thomas Ritz
Panic disorder (PD) is unique among the anxiety disorders in that panic symptoms are primarily of a physical nature. Consequently, comorbidity with medical illness is significant. This review examines the association between PD and medical illness. We identify shared pathophysiological and psychological correlates and illustrate how physiological activation in panic sufferers underlies their symptom experience in the context of the fight-orflight response and beyond a situation-specific response pattern. We then review evidence for bodily symptom perception accuracy in PD...
March 27, 2017: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/28375206/malpa1-null-mice-as-an-endophenotype-of-anxious-depression
#10
R D Moreno-Fernández, M Pérez-Martín, E Castilla-Ortega, C Rosell Del Valle, M I García-Fernández, J Chun, G Estivill-Torrús, F Rodríguez de Fonseca, L J Santín, C Pedraza
Anxious depression is a prevalent disease with devastating consequences and a poor prognosis. Nevertheless, the neurobiological mechanisms underlying this mood disorder remain poorly characterized. The LPA1 receptor is one of the six characterized G protein-coupled receptors (LPA1-6) through which lysophosphatidic acid acts as an intracellular signalling molecule. The loss of this receptor induces anxiety and several behavioural and neurobiological changes that have been strongly associated with depression...
April 4, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28370638/the-development-and-validation-of-static-and-adaptive-screeners-to-measure-the-severity-of-panic-disorder-social-anxiety-disorder-and-obsessive-compulsive-disorder
#11
Matthew Sunderland, Philip J Batterham, Alison L Calear, Natacha Carragher
A series of static and adaptive screeners for panic disorder, social anxiety disorder (SAD), and obsessive compulsive disorder (OCD) were developed and compared using data-driven methods to facilitate the measurement of each disorder in community samples. Data comprised 3175 respondents for the development sample and 3755 respondents for the validation sample, recruited independently using Facebook advertising. Item Response Theory (IRT) was utilized to develop static continuous screeners and to simulate computerized adaptive algorithms...
April 3, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/28347824/participation-of-dorsal-periaqueductal-gray-5-ht1a-receptors-in-the-panicolytic-like-effect-of-the-%C3%AE%C2%BA-opioid-receptor-antagonist-nor-bni
#12
Jhonatan Christian Maraschin, Camila Biesdorf Almeida, Marcel Pereira Rangel, Camila Marroni Roncon, Caio César Sestile, Hélio Zangrossi, Frederico Guilherme Graeff, Elisabeth Aparecida Audi
Panic patients may have abnormalities in serotonergic and opioidergic neurotransmission. The dorsal periaqueductal gray (dPAG) plays an important role in organizing proximal defense, related to panic attacks. The 5-HT1A receptor (5-HT1A-R) is involved in regulating escape behavior that is organized in the dPAG. Activation of κ-opioid receptor (KOR) in this region causes anxiogenic effects. In this study, we investigated the involvement of KOR in regulating escape behavior, using systemic and intra-dPAG injection of the KOR antagonist Nor-BNI...
March 24, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28344495/enantioselective-analysis-of-fluoxetine-in-pharmaceutical-formulations-by-capillary-zone-electrophoresis
#13
Melania Cârcu-Dobrin, Monica Budău, Gabriel Hancu, Laszlo Gagyi, Aura Rusu, Hajnal Kelemen
Fluoxetine is an antidepressant, a selective serotonin reuptake inhibitor (SSRI) used primarily in the treatment of major depression, panic disorder and obsessive compulsive disorder. Chiral separation of racemic fluoxetine is necessary due to its enantioselective metabolism. In order to develop a suitable method for chiral separation of fluoxetine, cyclodextrin (CD) modified capillary electrophoresis (CE) was employed. A large number of native and derivatized, neutral and ionized CD derivatives were screened to find the optimal chiral selector...
March 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28342947/what-good-are-positive-emotions-for-treatment-trait-positive-emotionality-predicts-response-to-cognitive-behavioral-therapy-for-anxiety
#14
Charles T Taylor, Sarah E Knapp, Jessica A Bomyea, Holly J Ramsawh, Martin P Paulus, Murray B Stein
OBJECTIVE: Cognitive behavioral therapy (CBT) is empirically supported for the treatment of anxiety disorders; however, not all individuals achieve recovery following CBT. Positive emotions serve a number of functions that theoretically should facilitate response to CBT - they promote flexible patterns of information processing and assimilation of new information, encourage approach-oriented behavior, and speed physiological recovery from negative emotions. We conducted a secondary analysis of an existing clinical trial dataset to test the a priori hypothesis that individual differences in trait positive emotions would predict CBT response for anxiety...
June 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28341617/internet-delivered-health-interventions-that-work-systematic-review-of-meta-analyses-and-evaluation-of-website-availability
#15
Mary Am Rogers, Kelsey Lemmen, Rachel Kramer, Jason Mann, Vineet Chopra
BACKGROUND: Due to easy access and low cost, Internet-delivered therapies offer an attractive alternative to improving health. Although numerous websites contain health-related information, finding evidence-based programs (as demonstrated through randomized controlled trials, RCTs) can be challenging. We sought to bridge the divide between the knowledge gained from RCTs and communication of the results by conducting a global systematic review and analyzing the availability of evidence-based Internet health programs...
March 24, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28325630/does-patient-reluctance-towards-exposure-and-psychologists-attitudes-about-evidence-based-practice-influence-treatment-recommendations-for-panic-disorder-an-experimental-investigation
#16
Nikolaos Kazantzis, Crystal Ford, Chiara Paganini, Frank M Dattilio, Davide Farchione
This study examined the effects of patient reluctance towards exposure on practitioners' subsequent treatment recommendations. Participants (N=236) were doctoral level psychologists who received a vignette of a patient with panic disorder, which either did (experimental group) or did not (control group) mention patient reluctance towards exposure. Evidence Based Practice (EBP) attitudes were also assessed and taken into account. A significant main effect of reluctance, averaged across all levels of EBP attitudes, and theoretical orientations was obtained (OR=2...
March 6, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28298187/icanadapt-early-protocol-randomised-controlled-trial-rct-of-clinician-supervised-transdiagnostic-internet-delivered-cognitive-behaviour-therapy-icbt-for-depression-and-or-anxiety-in-early-stage-cancer-survivors-vs-treatment-as-usual
#17
M J Murphy, J M Newby, P Butow, L Kirsten, K Allison, S Loughnan, M A Price, J Shaw, H Shepherd, J Smith, G Andrews
BACKGROUND: This RCT with two parallel arms will evaluate the efficacy of an internet-delivered transdiagnostic cognitive behavioural therapy (iCBT) intervention for the treatment of clinical depression and/or anxiety in early stage cancer survivors. METHODS/DESIGN: Early stage cancer survivors will be recruited via the research arm of a not-for-profit clinical research unit and randomised to an intervention (iCBT) group or a 'treatment as usual' (TAU) control group...
March 15, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28284107/clinical-characteristics-and-treatment-outcomes-of-patients-with-major-depressive-disorder-and-comorbid-anxiety-disorders-results-from-a-european-multicenter-study
#18
Markus Dold, Lucie Bartova, Daniel Souery, Julien Mendlewicz, Alessandro Serretti, Stefano Porcelli, Joseph Zohar, Stuart Montgomery, Siegfried Kasper
This naturalistic European multicenter study aimed to elucidate the association between major depressive disorder (MDD) and comorbid anxiety disorders. Demographic and clinical information of 1346 MDD patients were compared between those with and without concurrent anxiety disorders. The association between explanatory variables and the presence of comorbid anxiety disorders was examined using binary logistic regression analyses. 286 (21.2%) of the participants exhibited comorbid anxiety disorders, 10.8% generalized anxiety disorder (GAD), 8...
February 27, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28278599/mediators-of-treatment-outcomes-for-anxious-children-and-adolescents-the-role-of-somatic-symptoms
#19
Amy E Hale, Golda S Ginsburg, Grace Chan, Philip C Kendall, James T McCracken, Dara Sakolsky, Boris Birmaher, Scott N Compton, Anne Marie Albano, John T Walkup
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors are effective treatments for pediatric anxiety disorders. However, the mechanisms of these treatments are unknown. Previous research indicated that somatic symptoms are reduced following treatment, but it is unclear if their reductions are merely a consequence of treatment gains. This study examined reductions in somatic symptoms as a potential mediator of the relationship between treatment and anxiety outcomes. Participants were 488 anxious youth ages 7-17 (M = 10...
February 26, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28277857/usefulness-of-self-report-questionnaires-for-psychological-assessment-of-patients-with-tinnitus-and-hyperacusis-and-patients-views-of-the-questionnaires
#20
Hashir Aazh, Brian C J Moore
OBJECTIVE: The objective was to determine the relevance and applicability of psychological questionnaires to patients seeking help for tinnitus and/or hyperacusis. DESIGN: This was a questionnaire-based survey. The following questionnaires were administered: Generalised Anxiety Disorder (GAD-7), Short Health Anxiety Inventory (SHAI), Mini-Social Phobia Inventory (Mini-SPIN), Obsessive Compulsive Inventory-Revised (OCI-R), Panic Disorder Severity Scale-Self Report (PDSS-SR), Patient Health Questionnaire (PHQ-9) and Penn State Worry Questionnaire-Abbreviated version (PSWQ-A)...
March 9, 2017: International Journal of Audiology
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