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https://www.readbyqxmd.com/read/29771217/cognitive-behavioral-therapy-mindfulness-and-hypnosis-as-treatment-methods-for-generalized-anxiety-disorder
#1
Carolyn Daitch
Individuals suffering from generalized anxiety disorder (GAD) experience a broad range of physical, emotional, and cognitive distress. A hallmark of GAD is anxiety around making decisions. Many clinicians notice improvements in patients through specific modalities, such as mindfulness, hypnosis, and cognitive behavioral therapy (CBT); however, these individual methods sometimes fall short. Clinicians and researchers alike note that it can be more effective to combine these three methods into an integrative treatment protocol...
July 2018: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/29748350/prognostic-significance-of-creatinine-increases-during-an-acute-heart-failure-admission-in-patients-with-and-without-residual-congestion-a-post-hoc-analysis-of-the-protect-data
#2
Marco Metra, Gad Cotter, Stefanie Senger, Christopher Edwards, John G Cleland, Piotr Ponikowski, Guillermo C Cursack, Olga Milo, John R Teerlink, Michael M Givertz, Christopher M O'Connor, Howard C Dittrich, Daniel M Bloomfield, Adriaan A Voors, Beth A Davison
BACKGROUND: The importance of a serum creatinine increase, traditionally considered worsening renal function (WRF), during admission for acute heart failure has been recently debated, with data suggesting an interaction between congestion and creatinine changes. METHODS AND RESULTS: In post hoc analyses, we analyzed the association of WRF with length of hospital stay, 30-day death or cardiovascular/renal readmission and 90-day mortality in the PROTECT study (Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function)...
May 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29745910/misdiagnosed-patient-with-latent-autoimmune-diabetes-in-adults-case-report
#3
H Petreski
Latent Autoimmune Diabetes in Adults (LADA) is often misdiagnosed because it lacks both awareness and standardized diagnostic criteria. A 30-year-old patient with high blood glucose, HbA1c level 10.1% and positive GAD antibodies was diagnosed with type 1 diabetes but LADA was not ruled out. Patient refused to receive insulin therapy. He chose to follow the dietary restrictions and therapy with sulfonylurea, initiated by another physician. Following 7 months the patient's HbA1c values decreased, but never achieved the goal...
April 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29738424/effects-of-vaginal-estradiol-tablets-and-moisturizer-on-menopause-specific-quality-of-life-and-mood-in-healthy-postmenopausal-women-with-vaginal-symptoms-a-randomized-clinical-trial
#4
Susan J Diem, Katherine A Guthrie, Caroline M Mitchell, Susan D Reed, Joseph C Larson, Kristine E Ensrud, Andrea Z LaCroix
OBJECTIVE: Compare the effects of a vaginal estradiol tablet and a vaginal moisturizer, each to placebo, on menopause-related quality of life and mood in postmenopausal women with moderate-severe vulvovaginal symptoms. METHODS: A total of 302 postmenopausal women enrolled in a 12-week, double-blind, placebo-controlled randomized trial were assigned to vaginal 10 μg estradiol tablet plus placebo gel (n = 102), vaginal moisturizer plus placebo tablet (n = 100), or dual placebo (n = 100)...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29736130/applicability-evaluation-of-simplified-cognitive-behavioral-therapy
#5
Li Zhang, Zhipei Zhu, Fang Fang, Yuan Shen, Na Liu, Chunbo Li
Background: We have developed a structured cognitive behavioral therapy manual for anxiety disorder in China, and the present study evaluated the applicability of simplified cognitive behavioral therapy based on our previous research. Aims: To evaluate the applicability of simplified cognitive behavioral therapy (SCBT) on generalized anxiety disorder (GAD) by conducting a multi-center controlled clinical trial. Methods: A multi-center controlled clinical trial of SCBT was conducted on patients with GAD, including institutions specializing in mental health and psychiatry units in general hospitals...
April 25, 2018: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29724721/setd2-is-recurrently-mutated-in-whole-exome-sequenced-canine-osteosarcoma
#6
Sharadha Sakthikumar, Ingegerd Elvers, Jaegil Kim, Maja L Arendt, Rachael Thomas, Jason Turner-Maier, Ross Swofford, Jeremy Johnson, Steven E Schumacher, Jessica Alföldi, Erik Axelsson, Guillermo Couto, William Kisseberth, Mats E Pettersson, Gad Getz, Jennifer R S Meadows, Jaime F Modiano, Matthew Breen, Marcin Kierczak, Karin Forsberg-Nilsson, Voichita D Marinescu, Kerstin Lindblad-Toh
Osteosarcoma (OSA) is a debilitating bone cancer that affects humans, especially children and adolescents. A homologous form of OSA spontaneously occurs in dogs, and its differential incidence observed across breeds allows for the investigation of tumor mutations in the context of multiple genetic backgrounds. Using whole-exome sequencing and dogs from three susceptible breeds (22 golden retrievers, 21 Rottweilers, and 23 greyhounds), we found that OSA tumors show a high frequency of somatic copy number alterations (SCNA) affecting key oncogenes and tumor suppressor genes...
May 3, 2018: Cancer Research
https://www.readbyqxmd.com/read/29721364/audio-recording-for-independent-confirmation-of-clinical-assessments-in-generalized-anxiety-disorder
#7
Steven D Targum, Christopher Murphy, Jibran Khan, Laura Zumpano, Mark Whitlock, Arthur A Simen, Brendon Binneman
Objective : The assessment of patients with generalized anxiety disorder (GAD) to deteremine whether a medication intervention is necessary is not always clear and might benefit from a second opinion. However, second opinions are time consuming, expensive, and not practical in most settings. We obtained independent, second opinion reviews of the primary clinician's assessment via audio-digital recording. Design : An audio-digital recording of key site-based assessments was used to generate site-independent "dual" reviews of the clinical presentation, symptom severity, and medication requirements of patients with GAD as part of the screening procedures for a clinical trial (ClinicalTrials...
April 1, 2018: Innovations in Clinical Neuroscience
https://www.readbyqxmd.com/read/29719089/associations-between-therapists-occupational-burnout-and-their-patients-depression-and-anxiety-treatment-outcomes
#8
Jaime Delgadillo, David Saxon, Michael Barkham
BACKGROUND: Occupational burnout is common in mental health professionals, but its impact on patient outcomes is as yet uncertain. This study aimed to investigate associations between therapist-level burnout and patient-level treatment outcomes after psychological therapy. METHODS: We used multilevel modeling using depression (PHQ-9) and anxiety (GAD-7) outcomes data from 2,223 patients nested within 49 therapists. Therapists completed a survey including the Oldenburg Burnout Inventory (OLBI) and a job satisfaction scale (JDSS)...
May 2, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29713087/molecular-subtypes-of-diffuse-large-b-cell-lymphoma-are-associated-with-distinct-pathogenic-mechanisms-and-outcomes
#9
Bjoern Chapuy, Chip Stewart, Andrew J Dunford, Jaegil Kim, Atanas Kamburov, Robert A Redd, Mike S Lawrence, Margaretha G M Roemer, Amy J Li, Marita Ziepert, Annette M Staiger, Jeremiah A Wala, Matthew D Ducar, Ignaty Leshchiner, Ester Rheinbay, Amaro Taylor-Weiner, Caroline A Coughlin, Julian M Hess, Chandra S Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam A Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, Brian K Link, Anne J Novak, James R Cerhan, Thomas M Habermann, Reiner Siebert, Andreas Rosenwald, Aaron R Thorner, Matthew L Meyerson, Todd R Golub, Rameen Beroukhim, Gerald G Wulf, German Ott, Scott J Rodig, Stefano Monti, Donna S Neuberg, Markus Loeffler, Michael Pfreundschuh, Lorenz Trümper, Gad Getz, Margaret A Shipp
Diffuse large B cell lymphoma (DLBCL), the most common lymphoid malignancy in adults, is a clinically and genetically heterogeneous disease that is further classified into transcriptionally defined activated B cell (ABC) and germinal center B cell (GCB) subtypes. We carried out a comprehensive genetic analysis of 304 primary DLBCLs and identified low-frequency alterations, captured recurrent mutations, somatic copy number alterations, and structural variants, and defined coordinate signatures in patients with available outcome data...
April 30, 2018: Nature Medicine
https://www.readbyqxmd.com/read/29707037/efficacy-and-safety-of-a-formulated-herbal-granula-jiu-wei-zhen-xin-for-generalized-anxiety-disorder-a-meta-analysis
#10
Sheng Wang, Lin-Lin Zhao, Xin-Jian Qiu, Dong-Sheng Wang, Tao Tang, Jie-Kun Luo, Sui-Yu Hu, Hui-Yong Huang
Background: The traditional Chinese medicine formula Jiu Wei Zhen Xin Granula (JWZXG) is prescribed to treat generalized anxiety disorder (GAD) in China. This study was to assess the efficacy and safety of JWZXG in patients with GAD. Method: Data were pooled from 14 randomized controlled trials involving the assessment of mean changes of Hamilton Anxiety Rating Scale (HAMA) total scores, response rates, adverse event rates, quality, publication bias, and risk of bias...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29704969/a-pilot-study-of-emotion-regulation-therapy-for-generalized-anxiety-and-depression-findings-from-a-diverse-sample-of-young-adults
#11
Megan E Renna, Jean M Quintero, Ariella Soffer, Martin Pino, Leslie Ader, David M Fresco, Douglas S Mennin
Emotion regulation therapy (ERT) for generalized anxiety disorder (GAD) and accompanying major depressive disorder (MDD) is a theoretically derived, evidence-based treatment that integrates principles from traditional and contemporary cognitive-behavioral and experiential approaches with basic and translational findings from affect science to offer a blueprint for improving intervention by focusing on the motivational responses and corresponding self-referential regulatory characteristics. Preliminary evidence supports the efficacy of a 20-session version of ERT...
May 2018: Behavior Therapy
https://www.readbyqxmd.com/read/29704656/person-centered-analysis-of-psychological-traits-to-explain-heterogeneity-in-patient-reported-outcomes-of-coronary-artery-disease-the-thoresci-study
#12
Eveline van Montfort, Nina Kupper, Jos Widdershoven, Johan Denollet
BACKGROUND: Heterogeneity in the prognosis of coronary artery disease (CAD) patients may be explained by relatively stable individual psychological differences. Therefore, we studied multiple personality and coping traits using a person-centered approach, and examined the predictive value of this approach for patient-reported outcomes. METHOD: 657 CAD patients (age = 66.39 ± 10.6; 79% men) completed multiple self-report questionnaires focusing on demographics, negative affectivity and social inhibition (DS14), neuroticism and extraversion (EPQ), resilience (DRS-15), and coping styles (CISS) after undergoing percutaneous coronary intervention...
April 18, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29703452/a-population-based-examination-of-the-co-occurrence-and-functional-correlates-of-chronic-pain-and-generalized-anxiety-disorder
#13
Brian Csupak, Jordana L Sommer, Eric Jacobsohn, Renée El-Gabalawy
OBJECTIVES: This study aimed to: 1) Establish the prevalence of co-occurring chronic pain conditions (i.e., arthritis, back pain, and migraines) and generalized anxiety disorder (GAD), and 2) Examine levels of pain severity, disability, and work absenteeism among comorbid chronic pain conditions and GAD. METHODS: Data were analyzed from the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH; N = 25,113). Chi-square analyses assessed whether significant differences existed in pain severity in those with comorbid chronic pain and GAD versus pain conditions alone...
April 17, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29700833/influence-of-high-pressure-processing-on-the-generation-of-%C3%AE-aminobutyric-acid-and-microbiological-safety-in-coffee-beans
#14
Bang-Yuan Chen, Hsiao-Wen Huang, Ming-Ching Cheng, Chung-Yi Wang
BACKGROUND: The aim of this study was to investigated the influence of high-pressure processing (HPP) on GABA content, glutamic acid (Glu) content, glutamate decarboxylase (GAD) activity, growth of A. fresenii, and accumulated ochratoxin A content in coffee beans. RESULTS: The results indicated that coffee beans subjected to HPP at pressures ≥50 MPa for 5 min increased GAD activity and promoted the conversion of Glu to GABA, and showed a significantly doubling of GABA content as compared with unprocessed coffee beans...
April 27, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29698081/kundalini-yoga-for-generalized-anxiety-disorder-an-exploration-of-treatment-efficacy-and-possible-mechanisms
#15
M G Gabriel, Joshua Curtiss, Stefan G Hofmann, Sat Bir S Khalsa
The aim of this study was to examine the efficacy of Kundalini Yoga in reducing symptoms of generalized anxiety disorder (GAD) compared to a common treatment-as-usual condition using cognitive techniques. A secondary objective was to explore potential treatment mechanisms. Females aged 24 to 75 years with GAD ( n = 49) received either an 8-week Kundalini Yoga intervention ( n = 34) or an 8-week treatment-as-usual condition ( n = 15). The yoga condition resulted in lower levels of anxiety relative to the treatment-as-usual condition...
April 26, 2018: International Journal of Yoga Therapy
https://www.readbyqxmd.com/read/29675943/relationship-of-anxiety-with-joint-pain-and-its-management-a-population-survey
#16
Lauren A Barnett, Mark G Pritchard, John J Edwards, Ebenezer K Afolabi, Kelvin P Jordan, Emma L Healey, Andrew G Finney, Carolyn A Chew-Graham, Christian D Mallen, Krysia S Dziedzic
OBJECTIVES: The aims of the present study was to examine the associations between the severity of pain and anxiety in a community population reporting joint pain, and to investigate the management of joint pain in the presence of comorbid anxiety. METHODS: A population survey was carried out of people aged ≥45 years, registered with eight general practices in Cheshire, Shropshire and Staffordshire, UK. Respondents were asked to report pain intensity in their hands, hips, knees and feet (on a numerical rating scale), anxiety symptoms (Generalized Anxiety Disorder seven-item [GAD-7] scale) and guideline-recommended treatments used to manage pain...
April 20, 2018: Musculoskeletal Care
https://www.readbyqxmd.com/read/29663083/-self-hypnosis-training-for-in-hospital-chronic-pain-patients-a-retrolective-observational-study
#17
Peter C Keil, Nicole Lindenberg, Christoph L Lassen, Bernhard M Graf, Jens Meier, Christoph H Wiese
BACKGROUND: Hypnosis is probably one of the oldest therapies known to man. In the last decades modern hypnosis has mainly been used by psychotherapists; however, hypnosis is becoming increasingly more important as a therapeutic method in medicine. Hypnosis can be used for a variety of medical indications. In the literature there is much evidence for the effectiveness of hypnosis. The aim of the present investigation was to demonstrate the effectiveness of hypnosis in inpatient treatment of chronic pain patients and to present a self-hypnosis program, which can be easily integrated into pain therapy...
April 16, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29659102/initial-severity-and-antidepressant-efficacy-for-anxiety-disorders-obsessive-compulsive-disorder-and-posttraumatic-stress-disorder-an-individual-patient-data-meta-analysis
#18
Ymkje Anna de Vries, Annelieke M Roest, Johannes G M Burgerhof, Peter de Jonge
BACKGROUND: It has been suggested that antidepressant benefits are smaller for mild than severe depression. Because antidepressants are also used for anxiety disorders, obsessive-compulsive disorder (OCD), and posttraumatic stress disorder (PTSD), we examined the influence of severity for these disorders. METHODS: We used individual patient data of eight trials (3,430 participants) for generalized anxiety disorder (GAD); four trials (1,195 participants) for social anxiety disorder (SAD); four trials (1,132 participants) for OCD; three trials (1,071 participants) for PTSD; and 10 trials (2,151 participants) for panic disorder (PD)...
April 16, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29657012/antiprotozoal-treatment-of-canine-babesiosis
#19
Gad Baneth
Canine babesiosis is a tick-borne disease caused by several Babesia spp. which have different susceptebility to anti-protozoal drugs. A few drugs and drug combinations are used in the treatment of canine babesiosis often without complete parasite elimination leaving treated dogs as carriers which could relapse with clinical disease and also transmit infection further. Although the large form canine babesial species Babesia canis, Babesia vogeli and Babesia rossi are sensitive to the aromatic diamidines imidocarb dipropionate and diminazene aceturate, small form species such as Babesia gibsoni, Babesia conradae and Babesia vulpes (Theileria annae) are relatively resistant to these drugs and are treated with the combination of the hydroxynaphthoquinone atovaquone and the antibiotic azithromycin...
April 30, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29653295/feasibility-of-a-mindfulness-based-cognitive-therapy-group-intervention-as-an-adjunctive-treatment-for-postpartum-depression-and-anxiety
#20
Barbara Shulman, Royce Dueck, Deirdre Ryan, Genevieve Breau, Isabel Sadowski, Shaila Misri
BACKGROUND: Many women experience moderate-to-severe depression and anxiety in the postpartum period for which pharmacotherapy is often the first-line treatment. Many breastfeeding mothers are reticent to increase their dose or consider additional medication, despite incomplete response, due to potential adverse effects on their newborn. These mothers are amenable to non-pharmacological intervention for complete symptom remission. The current study evaluated the feasibility of an eight-week mindfulness-based cognitive therapy (MBCT) intervention as an adjunctive treatment for postpartum depression and anxiety...
January 2, 2018: Journal of Affective Disorders
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