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Gender specific therapies and disorders

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https://www.readbyqxmd.com/read/29746147/female-sex-and-gender-in-lung-sleep-health-and-disease-increased-understanding-of-basic-biological-pathophysiological-and-behavioral-mechanisms-leading-to-better-health-for-female-patients-with-lung-disease
#1
MeiLan K Han, Emilio Arteaga-Solis, John Blenis, Ghada Bourjeily, Deborah J Clegg, Dawn DeMeo, Jeanne Duffy, Ben Gaston, Nicola M Heller, Anna Hemnes, Elizabeth Petri Henske, Raksha Jain, Tim Lahm, Lisa H Lancaster, Joyce Lee, Marianne J Legato, Sherry McKee, Reena Mehra, Alison Morris, Y S Prakash, Martin R Stampfli, Rashmi Gopal-Srivastava, Aaron D Laposky, Antonello Punturieri, Lora Reineck, Xenia Tigno, Janine Clayton
Female sex/gender is an under-characterized variable in studies related to lung development and disease. Notwithstanding, many aspects of lung and sleep biology and pathobiology are impacted by female sex and female reproductive transitions. These may manifest as differential gene expression or peculiar organ development. Some conditions are more prevalent in women, such as asthma and insomnia, or in the case of LAM, are seen almost exclusively in women. In other diseases, presentation differs such as the higher frequency of exacerbations experienced by women with COPD or greater cardiac morbidity among women with sleep disordered breathing...
May 10, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29721718/an-up-to-date-review-of-pseudotumor-cerebri-syndrome
#2
REVIEW
John Glenn Burkett, Jessica Ailani
PURPOSE OF REVIEW: Idiopathic intracranial hypertension (IIH), pseudotumor cerebri syndrome (PTCS), and benign intracranial hypertension are all terms that have been used for a neurologic syndrome consisting of elevated intracranial pressure (ICP), headache and vision loss without mass lesion or underlying infection or malignancy. In this review article, categorization, diagnostic criteria, symptom management strategies, and disease treatment options for pseudotumor cerebri syndrome will be discussed...
May 2, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29661966/pallidal-deep-brain-stimulation-disrupts-pallidal-beta-oscillations-and-coherence-with-primary-motor-cortex-in-parkinson-s-disease
#3
Doris D Wang, Coralie de Hemptinne, Svjetlana Miocinovic, Jill L Ostrem, Nicholas B Galifianakis, Marta San Luciano, Philip A Starr
In Parkinson's disease (PD), subthalamic nucleus beta band oscillations are decreased by therapeutic deep brain stimulation (DBS) and this has been proposed as important to the mechanism of therapy. The globus pallidus is a common alternative target for PD with similar motor benefits as subthalamic DBS, but effects of pallidal stimulation in PD are not well studied, and effects of pallidal DBS on cortical function in PD are unknown. Here, in 20 PD and 14 isolated dystonia human patients of both genders undergoing pallidal DBS lead implantation, we recorded local field potentials (LFPs) from the globus pallidus and in a subset of these, recorded simultaneous sensorimotor cortex electrocorticography (ECoG) potentials...
April 16, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29606224/individual-versus-group-female-specific-cognitive-behavior-therapy-for-alcohol-use-disorder
#4
Elizabeth E Epstein, Barbara S McCrady, Kevin A Hallgren, Ayorkor Gaba, Sharon Cook, Noelle Jensen, Thomas Hildebrandt, Cathryn Glanton Holzhauer, Mark D Litt
OBJECTIVES: To test group-based Female-Specific Cognitive Behavioral Therapy (G-FS-CBT) for women with Alcohol Use Disorder (AUD) against an individual Female-Specific Cognitive Behavioral Therapy (I-FS-CBT). This aims of this paper are to describe G-FS-CBT development, content, feasibility, acceptability, group process, engagement in treatment, and within- and post-treatment outcomes. METHODS: Women with AUD (n=155) were randomly assigned to 12 manual-guided sessions of G-FS-CBT or I-FS-CBT; 138 women attended at least one treatment session...
May 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29538299/comparative-analysis-of-bone-structural-parameters-reveals-subchondral-cortical-plate-resorption-and-increased-trabecular-bone-remodeling-in-human-facet-joint-osteoarthritis
#5
Cordula Netzer, Pascal Distel, Uwe Wolfram, Hans Deyhle, Gregory F Jost, Stefan Schären, Jeroen Geurts
Facet joint osteoarthritis is a prominent feature of degenerative spine disorders, highly prevalent in ageing populations, and considered a major cause for chronic lower back pain. Since there is no targeted pharmacological therapy, clinical management of disease includes analgesic or surgical treatment. The specific cellular, molecular, and structural changes underpinning facet joint osteoarthritis remain largely elusive. The aim of this study was to determine osteoarthritis-related structural alterations in cortical and trabecular subchondral bone compartments...
March 14, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29511827/impulse-control-disorders-in-parkinson-s-disease
#6
REVIEW
Ana Marques, Franck Durif, Pierre-Olivier Fernagut
Impulse control disorders (ICD) are frequent side effects of dopamine replacement therapy (DRT) used in Parkinson's disease (PD) with devastating consequences on the patients and caregivers. ICD are behavioural addictions including compulsive gambling, shopping, sexual behaviour, and binge eating that are mainly associated with dopamine D2/D3 agonists. Their management is a real clinical challenge due to the lack of therapeutic alternative. Clinical studies have identified demographic and clinical risk factors for ICD such as younger age at disease onset, male gender, prior history of depression or substance abuse, REM sleep behaviour disorders and higher rate of dyskinesia...
March 7, 2018: Journal of Neural Transmission
https://www.readbyqxmd.com/read/29503545/treatment-patterns-health-care-resource-utilization-and-costs-in-japanese-adults-with-attention-deficit-hyperactivity-disorder-treated-with-atomoxetine
#7
Hideyuki Imagawa, Saurabh P Nagar, William Montgomery, Tomomi Nakamura, Masayo Sato, Keith L Davis
Objective: To describe the characteristics and medication treatment patterns of adult patients with attention-deficit/hyperactivity disorder (ADHD) prescribed atomoxetine in Japan. Materials and methods: A retrospective analysis of insurance claims data was conducted using the Japan Medical Data Center database. Adults (≥18 years) with ADHD who had ≥1 atomoxetine claim from January 1, 2013 to December 31, 2014, and ≥180 to ≤900 days of follow-up were included...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29484510/impact-of-quran-in-treatment-of-the-psychological-disorder-and-spiritual-illness
#8
Ali Ali Gobaili Saged, Mohd Yakub Zulkifli Mohd Yusoff, Faizuri Abdul Latif, Syed Mohammad Hilmi, Waleed Mugahed Al-Rahmi, Ahmed Al-Samman, Norma Alias, Akram M Zeki
This paper studies the effect of Quranic therapy on psychological diseases and spiritual diseases. The experiments have been conducted on a random sample with 121 patients from both genders. The procedures that have been followed were different sessions with the patients, who were given some verses from the Holy Quran to listen within a specific period of time. After that, each patient was given a remedy program. This study aimed to measure the effectiveness and responsiveness of patients to receive treatment through Quran...
February 26, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29445772/a-review-of-evidence-based-treatments-for-transgender-youth-diagnosed-with-social-anxiety-disorder
#9
REVIEW
Samantha Busa, Aron Janssen, Mallika Lakshman
In addition to the high prevalence of gender dysphoria among transgender youth, this population is at greater risk of suffering from additional mental health disorders, including social anxiety disorder, compared to their cisgender peers. Cognitive behavioral therapy (CBT) has been established as an effective form of treatment for social anxiety disorder. It is recommended that therapists modify and adapt CBT when working with minority groups such as transgender youth to ensure that the treatment is efficacious and culturally sensitive...
2018: Transgender Health
https://www.readbyqxmd.com/read/29356591/gender-specific-differences-in-access-to-polysomnography-and-prevalence-of-sleep-disorders
#10
Michael Auer, Birgit Frauscher, Margarethe Hochleitner, Birgit Högl
BACKGROUND: Previous studies have shown that women have less access or longer waiting times to high-tech medicine compared with men. This study aimed to detect possible gender differences in access to the diagnostic high-tech method of polysomnography (PSG). Furthermore, the study explored gender differences in prevalence of specific sleep diseases. MATERIALS AND METHODS: Source data of n = 1000 patients, who underwent PSG at the Medical University of Innsbruck, were reviewed...
April 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29190573/common-comorbidities-and-survival-in-ms-risk-for-stroke-type-1-diabetes-and-infections
#11
A Murtonen, S Kurki, K Hänninen, M Soilu-Hänninen, M-L Sumelahti
BACKGROUND: Survival in MS has increased during the era of disease modifying therapies, but life expectancy in MS patients is still reduced by several years. Increased risk for common comorbidities related to brain health, such as risk for circulatory diseases have been reported in MS and could affect survival. In this paper, we studied age- and gender adjusted risks for circulatory diseases and related disorders, and their impact on overall MS survival in population of Southwest Finland...
January 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29176959/gender-specific-relationship-between-obesity-and-major-depression
#12
Li Li, Barbara A Gower, Richard C Shelton, Xiaoyan Wu
Objective: Prior research suggests a bidirectional relationship between obesity and major depressive disorder (MDD), but the results have been heterogeneous. Differences between males and females in the association of MDD with obesity may contribute to inconsistent results. Thus, this study was designed to determine whether sex has a differential effect on the relationship between MDD and obesity, and to explore the potential mechanisms. Methods: All participants were diagnosed with MDD, and depression severity was measured using the 17-item Hamilton Depression Rating Scale...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29154553/a-randomized-trial-of-female-specific-cognitive-behavior-therapy-for-alcohol-dependent-women
#13
Elizabeth E Epstein, Barbara S McCrady, Kevin A Hallgren, Sharon Cook, Noelle K Jensen, Thomas Hildebrandt
This study compared Female-Specific Cognitive Behavioral Therapy (FS-CBT) to evidence-based, gender-neutral CBT (GN-CBT; Epstein & McCrady, 2009) for women with alcohol use disorder (AUD). Women (N = 99) with AUD, mean age 48, were randomly assigned to 12 outpatient manual-guided sessions of FS-CBT (n = 44) or GN-CBT (n = 55). Women were assessed at baseline and 3, 9 and 15 months after baseline for drinking and for specific issues common among women with AUD. A FS-CBT protocol was developed that was discriminable on treatment integrity ratings from GN-CBT...
February 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29120922/gender-dysphoria-in-youth-a-review-of-recent-literature
#14
Julia Cartaya, Ximena Lopez
PURPOSE OF REVIEW: Transgender individuals including pubertal young people require hormonal therapy, in conjunction with mental health support. These youths are a unique population, with specific and individual desires and needs as they move through the physical and mental transition to the gender with which they identify. RECENT FINDINGS: The number of transgender youth presenting for treatment is increasing rapidly. They continue to have a high prevalence of mental health disorders, though not when supported in their sex identities by family in younger age...
February 2018: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/29111860/identification-of-the-gender-specific-health-needs-of-women-following-lung-transplantation
#15
Emily E Robertson, Robin J Bell, Penelope J Robinson, Greg Snell, Bronwyn Levvey, Helen M Whitford, Jane Harris, Susan R Davis
BACKGROUND: Little is known of the prevalence and severity of menstrual dysfunction, climacteric symptoms, pelvic floor disorders, sexual problems, and psychological wellbeing after lung transplantation in women. MATERIALS AND METHODS: Adult female lung transplant recipients, attending the Alfred Hospital Lung Transplant Service in Melbourne, Australia participated in a women's health, cross-sectional questionnaire-based study. RESULTS: The 123 of 149 potential participants were recruited between September 2014 and July 2015...
November 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29071210/identifying-motor-functional-neurological-disorder-using-resting-state-functional-connectivity
#16
Jennifer Wegrzyk, Valeria Kebets, Jonas Richiardi, Silvio Galli, Dimitri Van de Ville, Selma Aybek
BACKGROUND: Motor functional neurological disorder (mFND) is a clinical diagnosis with reliable features; however, patients are reluctant to accept the diagnosis and physicians themselves bear doubts on potential misdiagnoses. The identification of a positive biomarker could help limiting unnecessary costs of multiple referrals and investigations, thus promoting early diagnosis and allowing early engagement in appropriate therapy. OBJECTIVES: To test whether resting-state (RS) functional magnetic resonance imaging could discriminate patients suffering from mFND from healthy controls...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28981882/electroconvulsive-therapy-selectively-enhanced-feedforward-connectivity-from-fusiform-face-area-to-amygdala-in-major-depressive-disorder
#17
Jiaojian Wang, Qiang Wei, Tongjian Bai, Xiaoqin Zhou, Hui Sun, Benjamin Becker, Yanghua Tian, Kai Wang, Keith Kendrick
Electroconvulsive therapy (ECT) has been widely used to treat the major depressive disorder (MDD), especially for treatment-resistant depression. However, the neuroanatomical basis of ECT remains an open problem. In our study, we combined the voxel-based morphology (VBM), resting-state functional connectivity (RSFC) and granger causality analysis (GCA) to identify the longitudinal changes of structure and function in 23 MDD patients before and after ECT. In addition, multivariate pattern analysis using linear support vector machine (SVM) was applied to classify 23 depressed patients from 25 gender, age and education matched healthy controls...
December 1, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28950817/specific-patient-features-affect-antiepileptic-drug-therapy-decisions-focus-on-gender-age-and-psychiatric-comorbidities
#18
Laura Rosa Pisani, Marina Nikanorova, Cecilie Johannessen Landmark, Svein Ivar Johannessen, Francesco Pisani
BACKGROUND: Patient features, apart from the type of seizures/epilepsy, affect markedly antiepileptic drug (AED) choice and dosage. The present review focuses on gender, age and psychiatric comorbidities which play a leading role in influencing antiepileptic treatment. METHODS: Reviews with large population of patients, controlled clinical trials, observational investigations, experimental studies and experimental reviews of experimental data, where appropriated, were analysed and illustrated to produce the most homogeneous indications possible...
2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28910748/local-functional-connectivity-density-is-closely-associated-with-the-response-of-electroconvulsive-therapy-in-major-depressive-disorder
#19
Jiaojian Wang, Qiang Wei, Xinru Yuan, Xiaoyan Jiang, Jinping Xu, Xiaoqin Zhou, Yanghua Tian, Kai Wang
BACKGROUND: Electroconvulsive therapy (ECT) has been demonstrated to be an effective treatment of major depressive disorder (MDD). However, the neuroanatomical basis of response to ECT is still largely unknown. METHODS: In present study, we used functional connectivity density (FCD) and resting-state functional connectivity (RSFC) to identify the relationship between the changes of resting-state activities and ECT responses in 23 MDD patients before and after ECT...
January 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28840391/respiratory-sinus-arrhythmia-in-cognitive-behavioral-therapy-for-posttraumatic-stress-symptoms-in-children-preliminary-treatment-and-gender-effects
#20
Rebecca S Lipschutz, Sarah A O Gray, Carl F Weems, Michael S Scheeringa
Cognitive behavioral therapy (CBT) is an efficacious treatment for posttraumatic stress disorder (PTSD) symptoms, but the effect of CBT on physiological indicators is largely unknown. Respiratory sinus arrhythmia (RSA) is an established parasympathetic marker of self-regulatory capacity and stress responsivity. The present study tested if and how resting RSA and RSA reactivity changed following treatment among a sample of children (n = 48) who experienced at least one traumatic event and presented with PTSD symptoms...
December 2017: Applied Psychophysiology and Biofeedback
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