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https://www.readbyqxmd.com/read/28638483/thermoacoustic-imaging-and-therapy-guidance-based-on-ultra-short-pulsed-microwave-pumped-thermoelastic-effect-induced-with-superparamagnetic-iron-oxide-nanoparticles
#1
Liewei Wen, Sihua Yang, Junping Zhong, Quan Zhou, Da Xing
Multifunctional nanoparticle-mediated imaging and therapeutic techniques are promising modalities for accurate localization and targeted treatment of cancer in clinical settings. Thermoacoustic (TA) imaging is highly sensitive to detect the distribution of water, ions or specific nanoprobes and provides excellent resolution, good contrast and superior tissue penetrability. TA therapy is a potential non-invasive approach for the treatment of deep-seated tumors. In this study, human serum albumin (HSA)-functionalized superparamagnetic iron oxide nanoparticle (HSA-SPIO) is used as a multifunctional nanoprobe with clinical application potential for MRI, TA imaging and treatment of tumor...
2017: Theranostics
https://www.readbyqxmd.com/read/28622848/average-male-and-female-virtual-dummy-model-biorid-and-evarid-simulations-with-two-seat-concepts-in-the-euro-ncap-low-severity-rear-impact-test-configuration
#2
Astrid Linder, Kristian Holmqvist, Mats Y Svensson
Soft tissue neck injuries, also referred to as whiplash injuries, which can lead to long term suffering accounts for more than 60% of the cost of all injuries leading to permanent medical impairment for the insurance companies, with respect to injuries sustained in vehicle crashes. These injuries are sustained in all impact directions, however they are most common in rear impacts. Injury statistics have since the mid-1960s consistently shown that females are subject to a higher risk of sustaining this type of injury than males, on average twice the risk of injury...
June 13, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28598900/interleaved-mapping-of-temperature-and-longitudinal-relaxation-rate-to-monitor-drug-delivery-during-magnetic-resonance-guided-high-intensity-focused-ultrasound-induced-hyperthermia
#3
Esther Kneepkens, Edwin Heijman, Jochen Keupp, Steffen Weiss, Klaas Nicolay, Holger Grüll
OBJECTIVES: Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a method to heat lesions noninvasively to a stable, elevated temperature and a well-suited method to induce local hyperthermia (41°C-43°C) in deep-seated tissues. Magnetic Resonance (MR) imaging provides therapy planning on anatomical images and offers temperature feedback based on near-real-time MR thermometry. Although constant acquisition of MR thermometry data is crucial to ensure prolonged hyperthermia, it limits the freedom to perform measurements of other MR parameters, which are of interest during hyperthermia treatments...
June 8, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28577906/dynamic-head-neck-stabilization-and-modulation-with-perturbation-bandwidth-investigated-using-a-multisegment-neuromuscular-model
#4
Riender Happee, Edo de Bruijn, Patrick A Forbes, Frans C T van der Helm
The human head-neck system requires continuous stabilization in the presence of gravity and trunk motion. We investigated contributions of the vestibulocollic reflex (VCR), the cervicocollic reflex (CCR), and neck muscle co-contraction to head-in-space and head-on-trunk stabilization, and investigated modulation of the stabilization strategy with the frequency content of trunk perturbations and the presence of visual feedback. We developed a multisegment cervical spine model where reflex gains (VCR and CCR) and neck muscle co-contraction were estimated by fitting the model to the response of young healthy subjects, seated and exposed to anterior-posterior trunk motion, with frequency content from 0...
May 17, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28572774/an-under-the-table-leg-movement-apparatus-and-changes-in-energy-expenditure
#5
Gabriel A Koepp, Graham Moore, James A Levine
Introduction: Deskwork contributes substantially to sedentariness. Here, we evaluated an under-the-table apparatus that was designed to promote leg movement (fidgeting) while seated. Our hypothesis was that the under-the-table apparatus would increase energy expenditure. Methods: We measured energy expenditure and heart rate in 26 people while they sat and worked using a standard chair, walked on a treadmill, and sat and worked using an under-the-desk apparatus that encouraged leg movement. Results: Energy expenditure increased significantly while using the under-the-table apparatus when compared to the standard office chair (standard chair, 81 ± 18 kcal/h; under-the-table apparatus, 96 ± 23 kcal/h) (P < 0...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28540940/modelling-charge-transfer-processes-in-c-2-tetrahydrofuran-collision-for-ion-induced-radiation-damage-in-dna-building-blocks
#6
Ewa Erdmann, Marie-Christine Bacchus-Montabonel, Marta Łabuda
Investigations of collision-induced processes involving carbon ions and molecules of biological interest, in particular DNA building blocks, are crucial to model the effect of radiation on cells in order to improve medical treatments for cancer therapy. Using carbon ions appears to be one of the most efficient ways to increase biological effectiveness to damage cancerous cells by irradiating deep-seated tumors. Therefore, interest in accurate calculations to understand fundamental processes occurring in ion-molecule collision systems has been growing recently...
May 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28532866/the-effects-of-12-weeks-pilates-inspired-exercise-training-on-functional-performance-in-older-women-a-randomized-clinical-trial
#7
Natália Donzeli Vieira, Daniela Testa, Paula Cristine Ruas, Tânia de Fátima Salvini, Aparecida Maria Catai, Ruth Caldeira Melo
BACKGROUND: Recent scientific evidence supports the benefits of Pilates exercises on postural balance and muscle strength of older persons. However, their effects on other aspects of physical fitness, which are also important for independent living in older age, are still unknown. OBJECTIVE: To investigate the effects of a 12-week Pilates-inspired exercise program on the functional performance of community-dwelling older women. METHODS: Forty community-dwelling older women were randomly enrolled in a Pilates-inspired exercise training (2 times/week, 60 min/session) (PG, n = 21, 66...
April 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28502412/computer-based-estimation-of-the-hip-joint-reaction-force-and-hip-flexion-angle-in-three-different-sitting-configurations
#8
J Van Houcke, A Schouten, G Steenackers, D Vandermeulen, C Pattyn, E A Audenaert
Sitting is part of our daily work and leisure activities and can be performed in different configurations. To date, the impact of different sitting configurations on hip joint loading has not been studied. We therefore evaluated the hip joint reaction force (HJRF) and hip flexion angle in a virtual representative male Caucasian population by means of musculoskeletal modelling of three distinct sitting configurations: a simple chair, a car seat and a kneeling chair configuration. The observed median HJRF in relation to body weight and hip flexion angle, respectively, was 22...
September 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28453104/-low-back-pain-perception-from-the-prolonged-use-of-a-dynamic-seat-in-sitting-posture
#9
Zuli T Galindo-Estupiñan, Maria F Maradei-García, Francisco Espinel-Correal
Objective To determine whether a tilting system located in the seat of a chair allows for performing voluntary macro-repositioning movements of the pelvis in order to reduce the perception of pain after a prolonged period in the sitting posture. Methods Eight women participated in the experiment. They were asked to sit on the chair with the tilting system and the chair without the tilting system for sixty minutes on two different days but carried out at the same time of day. Discomfort was assessed with the visual analogic scale...
June 2016: Revista de Salud Pública
https://www.readbyqxmd.com/read/28449637/the-effect-of-a-dynamic-chair-on-seated-energy-expenditure
#10
Aoife Synnott, Wim Dankaerts, Jan Seghers, Helen Purtill, Kieran O'Sullivan
Dynamic sitting approaches have been advocated to increase seated energy expenditure with the view of lessening the sedentary nature of the task. This study compared energy expenditure (EE) and overall body discomfort on a novel dynamic chair with a standard office chair. Fifteen pain-free participants completed a DVD viewing task on both chairs in a randomised order. Energy expenditure and discomfort were collected simultaneously. Linear mixed models were used to analyse steady-state EE recorded on each of the chairs...
May 5, 2017: Ergonomics
https://www.readbyqxmd.com/read/28426462/high-resolution-esophageal-manometry-interpretation-in-clinical-practice
#11
Rena Yadlapati
PURPOSE OF REVIEW: Esophageal high-resolution manometry (HRM) is the current state-of-the-art diagnostic tool to evaluate esophageal motility patterns and, as such, is widely adopted in clinical practice. This article will review the interpretation of esophageal HRM in clinical practice. RECENT FINDINGS: HRM uses a high-resolution catheter to transmit intraluminal pressure data that are subsequently converted into dynamic esophageal pressure topography (EPT) plots...
July 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28399877/overground-vs-treadmill-based-robotic-gait-training-to-improve-seated-balance-in-people-with-motor-complete-spinal-cord-injury-a-case-report
#12
Amanda E Chisholm, Raed A Alamro, Alison M M Williams, Tania Lam
BACKGROUND: Robotic overground gait training devices, such as the Ekso, require users to actively participate in triggering steps through weight-shifting movements. It remains unknown how much the trunk muscles are activated during these movements, and if it is possible to transfer training effects to seated balance control. This study was conducted to compare the activity of postural control muscles of the trunk during overground (Ekso) vs. treadmill-based (Lokomat) robotic gait training, and evaluate changes in seated balance control in people with high-thoracic motor-complete spinal cord injury (SCI)...
April 11, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28366027/detecting-destabilizing-wheelchair-conditions-for-maintaining-seated-posture
#13
Anna Crawford, Kiley Armstrong, Kenneth Loparo, Musa Audu, Ronald Triolo
PURPOSE: The purpose of this study was to detect and classify potentially destabilizing conditions encountered by manual wheelchair users with spinal cord injuries (SCI) to dynamically increase stability and prevent falls. METHODS: A volunteer with motor complete T11 paraplegia repeatedly propelled his manual wheelchair over level ground and simulated destabilizing conditions including sudden stops, bumps and rough terrain. Wireless inertial measurement units attached to the wheelchair frame and his sternum recorded associated accelerations and angular velocities...
April 1, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28343746/preliminary-development-of-an-advanced-modular-pressure-relief-cushion-testing-and-user-evaluation
#14
Tyler Freeto, Steven J Mitchell, Kath M Bogie
STUDY AIM: Effective pressure relief cushions are identified as a core assistive technology need by the World Health Organization Global Cooperation on Assistive Technology. High quality affordable wheelchair cushions could provide effective pressure relief for many individuals with limited access to advanced assistive technology. MATERIALS: Value driven engineering (VdE) principles were employed to develop a prototype modular cushion. Low cost dynamically responsive gel balls were arranged in a close packed array and seated in bilayer foam for containment and support...
March 20, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28322250/effects-of-ecological-restoration-projects-on-changes-in-land-cover-a-case-study-on-the-loess-plateau-in-china
#15
Jun Zhao, Yanzheng Yang, Qingxia Zhao, Zhong Zhao
Changes in land cover have become key components of global environmental change and represent the impact of human activity. To better understand the fundamental processes of land transition characteristics before and after the implementation of ecological programmes, we determined the dominant systematic changes in land cover in Yongshou, a hilly-gully region on the Loess Plateau. This was achieved by performing an in-depth analysis of a cross-tabulation matrix and a modified spatial dynamic degree model. Our results indicated that (1) forest land and cultivated land were the most important land cover types in Yongshou and their persistence would greatly affect the landscape pattern of the entire region; (2) the most significant changing signals in the study area during the periods 1992-2000 and 2000-2013 were from immature forest land to forest land, cultivated land to orchards and orchards to construction land; and (3) the region that experienced the most changes during 1992-2000 was the densely populated county seat of Yongshou; however, from 2000-2013, the region of most changes was Changning, a town located in the northcentral region of Yongshou...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28300175/dynamic-cortical-participation-during-bilateral-cyclical-ankle-movements-effects-of-aging
#16
Takashi Yoshida, Kei Masani, Karl Zabjek, Robert Chen, Milos R Popovic
The precise role of the human primary motor cortex in walking is unknown. Our previous study showed that the primary motor cortex may contribute to specific requirements of walking (i.e., maintaining a constant movement frequency and bilaterally coordinating the feet). Because aging can impair (i) the ability to fulfill the aforementioned requirements and (ii) corticomuscular communication, we hypothesized that aging would impair the motoneuronal recruitment by the primary motor cortex during bilateral cyclical movements...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28291488/patient-litter-system-response-in-a-full-scale-ch-46-crash-test
#17
Charles A Weisenbach, Tyler Rooks, Troy Bowman, Vince Fralish, B Joseph McEntire
U.S. Military aeromedical patient litter systems are currently required to meet minimal static strength performance requirements at the component level. Operationally, these components must function as a system and are subjected to the dynamics of turbulent flight and potentially crash events. The first of two full-scale CH-46 crash tests was conducted at NASA's Langley Research Center and included an experiment to assess patient and litter system response during a severe but survivable crash event. A three-tiered strap and pole litter system was mounted into the airframe and occupied by three anthropomorphic test devices (ATDs)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28278254/characterizing-the-community-use-of-an-ultralight-wheelchair-with-on-the-fly-adjustable-seating-functions-a-pilot-study
#18
Johanne Mattie, Jaimie Borisoff, William C Miller, Borna Noureddin
An ultralight manual wheelchair that allows users to independently adjust rear seat height and backrest angle during normal everyday usage was recently commercialized. Prior research has been performed on wheelchair tilt, recline, and seat elevation use in the community, however no such research has been done on this new class of manual ultralight wheelchair with "on the fly" adjustments. The objective of this pilot study was to investigate and characterize the use of the two adjustable seating functions available on the Elevation™ ultralight dynamic wheelchair during its use in the community...
2017: PloS One
https://www.readbyqxmd.com/read/28277553/the-impact-of-dynamic-seating-on-classroom-behavior-of-students-with-autism-spectrum-disorder
#19
Nader Matin Sadr, Hojjat Allah Haghgoo, Sayyed Ali Samadi, Mehdi Rassafiani, Enayatollah Bakhshi, Hossein Hassanabadi
OBJECTIVE: Children with autism have sitting and on-task behavior problems in class. In this study, the effect of three alternative classroom-seating devices such as regular classroom chairs, therapy balls, and air cushions were examined on students' classroom behavior. MATERIALS & METHODS: 15 students with autism participated in this A1-B-A2-C multiple treatments study from Mashhad's Tabasom School, Mashhad, Iran in 2014. Students' behaviors were video recorded in three phases: sitting on their common chairs during phase A, air-sit cushioned in phase B, and ball chairs in phase C...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28267762/impaired-perception-of-surface-tilt-in-progressive-supranuclear-palsy
#20
Marian L Dale, Fay B Horak, W Geoffrey Wright, Bernadette M Schoneburg, John G Nutt, Martina Mancini
INTRODUCTION: Progressive supranuclear palsy (PSP) is characterized by early postural instability and backward falls. The mechanisms underlying backward postural instability in PSP are not understood. The aim of this study was to test the hypothesis that postural instability in PSP is a result of dysfunction in the perception of postural verticality. METHODS: We gathered posturography data on 12 subjects with PSP to compare with 12 subjects with idiopathic Parkinson's Disease (PD) and 12 healthy subjects...
2017: PloS One
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