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Bridget Ellsworth, Atul F Kamath
Background. Pigmented villonodular synovitis (PVNS) is a rare benign tumor affecting large joints and prompts excision to prevent local destruction of the joint. The purpose of this case report is to describe two differing surgical approaches for management of PVNS of the hip in patients requiring concomitant treatment for additional hip pathology. Methods. This report discusses the presentation, clinical and radiographic findings, and operative management of two contrasting cases of PVNS of the hip. Case 1 describes a 31-year-old female with localized PVNS in addition to a labral tear treated with arthroscopic labral repair followed by tumor excision via a mini-open incision...
2017: Case Reports in Orthopedics
Ryan A Williams, Robert K Jackler, C Eduardo Corrales
OBJECTIVE: Describe benign lesions arising from the temporomandibular joint (TMJ) that presented as masses in the external auditory canal (EAC). STUDY DESIGN: Retrospective case series of two academic medical centers. PATIENTS: Six patients with lesions emanating from the TMJ that presented as EAC masses. Lesions included pigmented villonodular synovitis (PVNS), nodular fasciitis, foramen of Huschke herniation with salivary fistula, fibroepithelial polyp, superficial angiomyxoma, and giant cell tumor (GCT)...
April 2017: Otology & Neurotology
Amine M Samoudi, Stefan Kampusch, Emmeric Tanghe, Jozsef C Széles, Luc Martens, Eugenijus Kaniusas, Wout Joseph
OBJECTIVE: Percutaneous stimulation of the auricular branch of the vagus nerve (pVNS) by miniaturized needle electrodes in the auricle gained importance as a treatment for acute and chronic pain. The objective is to establish a realistic numerical model of pVNS and investigate the effects of stimulation waveform, electrodes' depth, and electrodes' position on nerve excitation threshold and the percentage of stimulated nerves. METHODS: Simulations were performed with Sim4Life...
February 13, 2017: Medical & Biological Engineering & Computing
Qian Hua, Jianming Ni
Pigmented villonodular synovitis (PVNS) is a proliferative disorder of unknown etiology that originates from the synovial membranes of joints. Some PVNS lesions have been misdiagnosed as malignancy due to their tumorlike imaging findings. There are few reports of PVNS on nuclear 3-phase bone imaging. However, 3-phase Tc-MDP bone scan can offer additional information about the dynamic flow features of the lesion, which may do help in differential benign and malignant. The present report describes 3-phase bone imaging in a surgically proven case of PVNS with tumorlike appearance and atypical location...
March 2017: Clinical Nuclear Medicine
Chirag Kapoor, Maulik Jhaveri, Rishit Soni, Malkesh Shah, Parth Rathi, Paresh Golwala
Pigmented villonodular synovitis (PVNS) is a rare, benign, but potentially locally aggressive and recurrent condition characterized by synovial proliferation and hemosiderin deposition inside the joints, tendon sheaths, and bursae. It usually affects the large joints such as hip, knee, and ankle. We report a case of PVNS of the knee joint in a young female which was treated by subtotal synovectomy alone without the use of adjuvants. At the 14-month follow-up, the patient was pain free and had no signs of disease recurrence...
October 4, 2016: Curēus
Pankaj Sharma, Vivek Tiwari, Shah Alam Khan, Shishir Rastogi
Pigmented villo-nodular synovitis (PVNS) is a common disease entity particularly in the knee joint but its incidence in the foot is quite rare. A case of PVNS of the second toe that presented at the outpatient department with an insidious onset and slowly progressive painful swelling of the toe associated with stiffness is presented. The mass was subsequently excised and the diagnosis confirmed by histo-pathology samples. The patient's symptoms improved significantly after the operation. This case is one of the very few reported cases of PVNS involvement of flexor tendon sheath of the foot...
August 2016: Foot
Qian-Qian Gao, Yuan-Yong Feng, Ling-Xue Bu, Kai Song, Xin Dai, Wei Shang
Pigmented villonodular synovitis (PVNS) is a benign, proliferative disorder of synovium. It often affects the knee, and rarely occurs in the temporomandibular joint (TMJ). This paper reported a 45-year-old male patient with PVNS of the TMJ, who was referred with a chief complaint of slowly growing and painless preauricular mass that was noticed about 1 year. Radical excision and follow-up were conducted, no recurrence and metastasis were noted.
June 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
Ido Maor, Amos Shalev, Adi Mizrahi
In the auditory system, early neural stations such as brain stem are characterized by strict tonotopy, which is used to deconstruct sounds to their basic frequencies. But higher along the auditory hierarchy, as early as primary auditory cortex (A1), tonotopy starts breaking down at local circuits. Here, we studied the response properties of both excitatory and inhibitory neurons in the auditory cortex of anesthetized mice. We used in vivo two photon-targeted cell-attached recordings from identified parvalbumin-positive neurons (PVNs) and their excitatory pyramidal neighbors (PyrNs)...
September 6, 2016: Cerebral Cortex
Liang Zhao, Kaiyu Zhou, Yimin Hua, Yifei Li, Dezhi Mu
INTRODUCTION: Pigmented villonodular synovitis (PVNS) is a rare, benign proliferative disorder of the synovial membrane that typically presents in adults and affects a single joint. Multifocal PVNS is very rare, particularly in childhood. We reported a rare case of multifocal PVNS affecting over 20 joints in a child. CLINICAL PROCEDURE: A 7-year-old female patient had a 6-month history of multifocal joints swelling with mild pain. She was diagnosed as polyarticular juvenile idiopathic arthritis at a local hospital...
August 2016: Medicine (Baltimore)
Michalis Mazonakis, Antonis Tzedakis, Efrossyni Lyraraki, John Damilakis
Pigmented villonodular synovitis (PVNS) is a benign disease affecting synovial membranes of young and middle-aged adults. The aggressive treatment of this disorder often involves external-beam irradiation. This study was motivated by the lack of data relating to the radiation exposure of healthy tissues and radiotherapy-induced cancer risk. Monte Carlo methodology was employed to simulate a patient's irradiation for PVNS in the knee and hip joints with a 6 MV photon beam. The average radiation dose received by twenty-two out-of-field critical organs of the human body was calculated...
September 7, 2016: Physics in Medicine and Biology
Ashley Startzman, Devin Collins, Dominic Carreira
OBJECTIVES: Benign synovial diseases of the hip including Synovial Chondromatosis (SC) and Pigmented Villonodular Synovitis (PVNS) are devastating diseases. Initially, patients present with hip pain unrelieved by conservative measures. The diagnosis of PVNS and SC are often delayed, leading to progression of joint damage. The purpose of this review is to present the latest on the diagnosis, management, and prognosis of SC and PVNS of the hip. METHODS: An extensive systematic search of MEDLINE and PUBMED Databases was performed...
November 2016: Physician and Sportsmedicine
Jonelle Petscavage, Felix S Chew
Hoffa's syndrome involves inflammation of the infrapatellar fat pad secondary to direct trauma or microtrauma. Alternative sources of inflammation of Hoffa's fat pad include synovial processes such as pigmented villonodular synovitis (PVNS) and osteochondromatosis. Recently, a few cases of inflammation of Hoffa's fat pad secondary to human immunodeficiency virus (HIV) have been described. Our case presents an HIV patient with Hoffa's fat-pad inflammation as well as prefemoral fat-pad edema, posterior soft-tissue inflammation, and bone infarction...
2010: Radiology case reports
Hsiu Su, Elaine Gould, James Penna, Hong Meng
There are only a few reported cases in the literature of pigmented villonodular synovitis (PVNS) involving the elbow. Even more rare is its occurrence in the pediatric population as this condition mainly affects young adults. We report a unique case of an 8 year old girl presenting with diffuse form of PVNS of the elbow. The diagnosis is often not considered by clinical history and plain films as both are nonspecific in suggesting PVNS. MRI demonstrates the characteristic findings of PVNS, and therefore, is the imaging modality of choice for the evaluation of PVNS...
2008: Radiology case reports
Cheung Man Hong, Lui Tun Hing
INTRODUCTION: Pigmented villonodular synovitis (PVNS) is a proliferative condition of the synovium, which is composed of nodules and/or villi and has an abundant number of hemosiderin-laden macrophages. CASE REPORT: A 10-year-old boy presented with an acute irritable knee. Emergency arthroscopy showed a nodular PVNS in the intercondylar notch. The symptoms resolved after resection of the lesion. CONCLUSION: PVNS of the knee in children is a rare entity...
July 2015: Journal of Orthopaedic Case Reports
Nikhil Gokhale, Shaligam Purohit, Pradeep B Bhosale
INTRODUCTION: Pigmented villonodular synovitis is an uncommon disease characterized by hyperplastic synovium, large effusions and bone erosions. It commonly mimics other conditions. As a result, the diagnosis may remain elusive, as the classic signs of tenderness and effusion are not specific. Occasionally, PVNS presents as a popliteal cyst, which may divert attention from intra-articular pathology. In this article, we describe a case of pigmented villonodular synovitis that presented with a popliteal cyst as the chief problem...
July 2015: Journal of Orthopaedic Case Reports
Samir Dwidmuthe, Devashis Barick, Tarun Rathi
INTRODUCTION: Pigmented Villonodular Synovitis (PVNS) of knee joint is a rare disorder of Synovium. Hip and knee joint are commonly affected joints. The knee PVNS presents as a localized or diffuse form. Diagnosis if often delayed and permanent joint damage occurs with advanced disease. Ultrasound examination shows fluid collection and synovial hypertrophy. Magnetic resonance imaging helps in clinching the diagnosis. Final confirmation of PVNS is done with histopathological examination of synovial tissue removed...
April 2015: Journal of Orthopaedic Case Reports
Radha Sistla, Vidyasagar J V S, Tameem Afroz
INTRODUCTION: Malignant pigmented villonodular synovitis (PVNS) or Malignant giant cell tumour tendon sheath (MGCTTS) is a controversial and debatable lesion. Few case reports have indicated the potential for metastasis.1These aggressive cases are designated malignant giant cell tumour tendon sheath or malignant PVNS. Less than 20 cases are described in literature. We report a case of 65 year old lady who was diagnosed eight years back as pigmented villonodular synovitis. She had multiple local recurrences and now presented with lymphnodal metastases, which is extremely rare...
October 2014: Journal of Orthopaedic Case Reports
Valerio Belgrano, Ilan Ben-Shabat, Peter Bergh, Roger Olofsson Bagge
BACKGROUND: Isolated limb perfusion (ILP) is an established and effective treatment for advanced melanoma and soft tissue sarcomas of the extremities with a high overall response rate. The aim of this study was to describe our experience of ILP for more rare types of tumours. METHODS: Patients with Merkel cell carcinoma (MCC) (n = 4), squamous cell carcinoma (SCC) (n = 2), B-cell lymphoma (n = 1), desmoid tumours (n = 3), pigmented villonodular synovitis (PVNS) (n = 1) and giant cell tumour (n = 1) were treated with ILP and analysed retrospectively...
September 2016: International Journal of Hyperthermia
Abdellatif Benabbouha, Jonathan Basinga, Ismail Anteri, Abdelouab Jaafar
Pigmented villonodular synovitis (PVNS) is a rare pseudotumoral proliferative benign condition of unknown etiology, affecting synovial joints. It can also develop in the synovial bursae and in the tendon sheaths. It usually affects large joints, such as the knee and the hip. Ankle is a rare location, with only a few cases reported in the literature. We report a case of a 52 year old patient with a PVS of the right ankle. She received a subtotal synovectomy. After 2 years of follow-up there was no clinical recurrence...
2016: Pan African Medical Journal
Kiersten Pianosi, Matthew Rigby, Robert Hart, Jonathan Trites, S Mark Taylor
Pigmented villonodular synovitis (PVNS) is a rare and benign proliferative disorder of synovium with potentially locally aggressive growth and invasion of the bone. Occurring within the joints, tendon sheaths, and bursae, it is most commonly a monoarticular disease affecting large joints. In particular, most cases of PVNS occur in the knee. PVNS of the temporomandibular joint (TMJ) is a highly rare disorder, with approximately 60 cases reported. Herein, we present a unique case of an elderly male presenting with ear pain and subsequently diagnosed with PVNS of the TMJ with a history of trauma to the area...
April 2016: Plastic and Reconstructive Surgery. Global Open
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