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https://www.readbyqxmd.com/read/28430338/yap-taz-and-areg-expression-in-eighth-cranial-nerve-schwannoma
#1
Alessandro Martini, Gino Marioni, Elisabetta Zanoletti, Rocco Cappellesso, Roberto Stramare, Elena Fasanaro, Chiara Faccioli, Luciano Giacomelli, Luca Denaro, Domenico D'Avella, Antonio Mazzoni, Ambrogio Fassina
BACKGROUND: Although the diagnosis and treatment of eighth cranial nerve (VIII CN) schwannoma (acoustic neuroma) has improved over the years, no factors capable of predicting tumor growth have been identified as yet. This study is a preliminary investigation of the expression in sporadic VIII CN schwannomas of Yes-associated protein (YAP), transcriptional coactivator with PDZ-binding motif (TAZ), and amphiregulin (AREG), a direct target gene of YAP and TAZ. The expression of YAP, TAZ and AREG was correlated with the volumetric dimensions of tumors on contrast-enhanced magnetic resonance imaging (ceMRI)...
April 7, 2017: International Journal of Biological Markers
https://www.readbyqxmd.com/read/28293490/regenerative-peripheral-nerve-interfaces-for-the-treatment-of-postamputation-neuroma-pain-a-pilot-study
#2
Shoshana L Woo, Theodore A Kung, David L Brown, James A Leonard, Brian M Kelly, Paul S Cederna
BACKGROUND: Originally designed for prosthetic control, regenerative peripheral nerve interfaces (RPNIs) prevent neuroma formation by providing free muscle grafts as physiological targets for peripheral nerve ingrowth. We report the first series of patients undergoing RPNI implantation for treatment of symptomatic postamputation neuromas. METHODS: A retrospective case series of all amputees undergoing RPNI implantation for treatment of symptomatic neuromas between November 2013 and June 2015 is presented...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28264236/influencing-factors-analysis-of-facial-nerve-function-after-the-microsurgical-resection-of-acoustic-neuroma
#3
WenMing Hong, HongWei Cheng, XiaoJie Wang, ChunGuo Feng
OBJECTIVE: To explore and analyze the influencing factors of facial nerve function retainment after microsurgery resection of acoustic neurinoma. METHODS: Retrospective analysis of our hospital 105 acoustic neuroma cases from October, 2006 to January 2012, in the group all patients were treated with suboccipital sigmoid sinus approach to acoustic neuroma microsurgery resection. We adopted researching individual patient data, outpatient review and telephone followed up and the House-Brackmann grading system to evaluate and analyze the facial nerve function...
March 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28178141/a-non-surgical-approach-to-the-management-of-exposure-keratitis-due-to-facial-palsy-by-using-mini-scleral-lenses
#4
Victor Zaki
RATIONALE: This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS: Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of good functional vision. Mini-scleral lens keep the cornea covered by saline solution all wearing hours...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28175932/-nerve-injuries-and-traumatic-lesions-of-the-brachial-plexus-imaging-diagnostics-and-therapeutic-options
#5
D Schwarz, M T Pedro, C Brand, M Bendszus, G Antoniadis
CLINICAL/METHODICAL ISSUE: Traumatic lesions of peripheral nerves and the brachial plexus are feared complications because they frequently result in severe functional impairment. The prognosis is greatly dependent on the correct early diagnosis and the right choice of treatment regimen. It is important to distinguish between open and closed injuries. STANDARD RADIOLOGICAL METHODS: Initial imaging must critically evaluate or prove nerve continuity and is commonly achieved by high-resolution ultrasonography...
February 7, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28149725/correction-of-crossover-toe-deformity-by-arthroscopically-assisted-plantar-plate-tenodesis
#6
Tun Hing Lui
Plantar plate deficiency is the major pathology causing metatarsophalangeal joint instability. As the joint subluxates dorsally, the lumbrical is tethered at the medial side of the joint by the deep metatarsal ligament and becomes a deforming force for the development of crossover toe deformity. Plantar plate repair or reconstruction is a logical surgical treatment option. This can be performed through a dorsal or plantar approach. The purpose of this technical note is to report a minimally invasive technique of crossover toe deformity correction by suturing the plantar plate to the extensor tendon...
December 2016: Arthroscopy Techniques
https://www.readbyqxmd.com/read/27999504/neurectomy-outcomes-in-patients-with-morton-neuroma-comparison-of-plantar-vs-dorsal-approaches
#7
Alexander Habashy, Gonzalo Sumarriva, Robert J Treuting
BACKGROUND: Morton neuroma is a compressive neuropathy of the plantar digital nerve. Several surgical approaches have been used to treat painful Morton neuroma, with each approach having distinct advantages and disadvantages. For this study, we used validated outcome assessment tools to retrospectively compare patient satisfaction with 2 approaches. METHODS: The medical records and survey responses of 37 patients with 42 neuromas were evaluated with respect to outcomes and patient satisfaction after neurectomies performed through either a plantar or dorsal surgical approach by one Ochsner Clinic Foundation attending physician...
2016: Ochsner Journal
https://www.readbyqxmd.com/read/27928936/reconstruction-of-gluteal-deformities-a-systematic-review-and-experience-of-four-cases
#8
Mathias Tremp, Pietro Giovanni di Summa, Carlo M Oranges, Dirk J Schaefer, Daniel Felix Kalbermatten
BACKGROUND: The reconstruction of gluteal deformities remains a major challenge. The aim of this article is to provide a systematic review of the literature concerned, and to present a case series with representative defects from various zones. METHODS: A review of the literature was performed using PubMed, EMBASE, and The Cochrane Library, in accordance with the PRISMA statement. Quality of evidence was rated according to GRADE. Patients with various buttock deformities were included and, depending on the defect, the reconstructive techniques applied consisted of lipoinjection, local fasciocutaneous flap, or pedicled gracilis muscle flap...
December 8, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27891301/how-far-have-we-come-in-the-field-of-nerve-regeneration-after-trigeminal-nerve-injury
#9
REVIEW
Annika Rosén, Arezo Tardast, Tie-Jun Shi
Patients suffering from nerve injury with sensory disturbances or orofacial pain have greatly reduced quality of life, and it is a big cost for the society. Abnormal sensations caused by trigeminal nerve injury often become chronic, severely debilitating, and extremely difficult to treat. In general, non-invasive treatment such as drug treatment has been insufficient, and there are currently few available effective treatments. Surgical interventions such as end-to-end connection or nerve grafting have disadvantages such as donor site morbidity or formation of neuroma...
2016: Current Oral Health Reports
https://www.readbyqxmd.com/read/27857863/key-perspectives-on-woven-endobridge-device-for-wide-necked-bifurcation-aneurysms-endoscopic-endonasal-clipping-of-intracranial-aneurysms-retrosigmoid-versus-translabyrinthine-approaches-for-acoustic-neuromas-and-impact-of-local-intraoperative-steroid-administration
#10
https://www.readbyqxmd.com/read/27857505/glomus-tumours-of-the-hand-review-of-literature
#11
REVIEW
Vivek Machhindra Morey, Bhavuk Garg, Prakash P Kotwal
Glomus tumours are rare benign vascular neoplasms commonly found in the hand particularly in subungual region. Though, its aetiology remains largely unknown, several hypotheses have been made to explain the etiopathogenesis and cause of pain. These tumours usually present as a bluish or pinkish red discolouration of the nail plate with classical triad of localised tenderness, severe pain, and cold sensitivity. Nevertheless, differential diagnosis of other painful tumours, such as leiomyoma, eccrine spiradenoma, haemangioma, neuroma, osteochondroma, or mucous cyst should always be kept in mind while evaluating a patient with severe pain in the tip of the finger...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/27765099/-exclusive-endoscopic-transsuprameatal-approach-for-the-pure-intracanalicular-acoustic-neuroma
#12
Q H Zhang, X Y Ding, Z L Wang
No abstract text is available yet for this article.
October 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27627563/long-term-results-of-neurectomy-through-a-dorsal-approach-in-the-treatment-of-morton-s-neuroma
#13
Paweł Reichert, Krzysztof Zimmer, Jarosław Witkowski, Witold Wnukiewicz, Sebastian Kuliński, Jerzy Gosk
BACKGROUND: Morton's neuroma, a painful enlargement of the plantar digital nerve between the metatarsal heads, is a common cause of metatarsalgia. The etiology and treatment are still a controversial matter. OBJECTIVES: The objective of this study was to evaluate the long-term follow-up results of neurectomy through a dorsal approach and to identify prognostic factors that can affect the final outcome. MATERIAL AND METHODS: The study included 41 patients who were treated for Morton's neuroma...
March 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27593791/unilateral-acoustic-neuromas-in-childhood-without-evidence-of-neurofibromatosis-experience-in-10-patients-at-a-single-institute
#14
Luxin Yin, Zhenyu Ma, Chunde Li, Shiqi Luo
AIM: We investigated the clinical presentation and management issues of unilateral vestibular schwannomas in childhood without evidence of neurofibromatosis. MATERIAL AND METHODS: Ten pediatric patients with unilateral vestibular schwannomas and no evidence of neurofibromatosis were treated by the senior author at Tiantan Hospital from January 1994 to December 2014. The clinical manifestations, neuroimaging findings, treatment methods, and therapeutic results were retrospectively reviewed...
December 28, 2015: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27579849/multimodality-imaging-review-of-the-post-amputation-stump-pain
#15
REVIEW
Nawaraj Subedi, Priam Heire, Vinay Parmer, Simon Beardmore, Chooi Oh, Fergus Jepson, Syed I Ali
Limb amputation is one of the oldest known surgical procedures performed for a variety of indications. Little surgical technical improvements have been made since the first procedure, but perioperative and post-operative refinements have occurred over time. Post-amputation pain (PAP) of the stump is a common complication but is an extremely challenging condition to treat. Imaging allows early diagnosis of the underlying cause so that timely intervention is possible to minimize physical disability with its possible psychological and socioeconomic implications...
December 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27565388/the-fully-endoscopic-acoustic-neuroma-surgery
#16
REVIEW
Daniele Marchioni, Marco Carner, Alessia Rubini, João Flávio Nogueira, Barbara Masotto, Matteo Alicandri-Ciufelli, Livio Presutti
Surgical approaches to vestibular schwannomas (VS) are widely known and extensively recorded. For the first time, an exclusive endoscopic approach to the internal acoustic canal (IAC) was described and used to safely remove a cochlear schwannoma involving IAC in March 2012. The aim of this article was to summarize indications and technique to treat intracanalicular VS by transcanal/transpromontorial endoscopic approach. Because management of intracanalicular VSs is complex and strongly debated, this kind of therapeutic option in the appropriate and selected cases could modify classic concepts of the management of this pathology...
October 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27556032/approaches-to-peripheral-nerve-repair-generations-of-biomaterial-conduits-yielding-to-replacing-autologous-nerve-grafts-in-craniomaxillofacial-surgery
#17
REVIEW
Robert Gaudin, Christian Knipfer, Anders Henningsen, Ralf Smeets, Max Heiland, Tessa Hadlock
Peripheral nerve injury is a common clinical entity, which may arise due to traumatic, tumorous, or even iatrogenic injury in craniomaxillofacial surgery. Despite advances in biomaterials and techniques over the past several decades, reconstruction of nerve gaps remains a challenge. Autografts are the gold standard for nerve reconstruction. Using autografts, there is donor site morbidity, subsequent sensory deficit, and potential for neuroma development and infection. Moreover, the need for a second surgical site and limited availability of donor nerves remain a challenge...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27345875/-relationship-and-influencing-factors-between-the-amplitude-change-of-supramaximal-facial-nerve-stimulation-during-acoustic-neuroma-removal-and-facial-function-outcome
#18
H Jia, B Y Fan, L X Hu, Z H Zhang, Z Y Wang, Q Huang, J Yang, H Wu
OBJECTIVE: To investigate the relationship between the amplitude change of supramaximal facial nerve stimulation during acoustic neuroma removal and facial function outcome, and discuss its influencing factors. METHODS: Retrospective study of 34 acoustic neuroma patients. Intraoperative amplitude by supramaximal stimulation, facial function outcome, tumor size, surgical approach, facial nerve course pattern, and tumor cystic status, as well as tumor adhesion degree were collected and analyzed by SPSS 17...
June 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27345874/-analysis-of-the-effect-of-cochlear-implant-for-the-patients-with-acoustic-neuroma-in-the-only-hearing-ear
#19
Z R Huo, Z H Zhang, Q Huang, J Yang, Y Li, M P Huang, H Wu
OBJECTIVE: To discuss the method as well as effect of hearing restoration for patients with acoustic neuroma (AN) in the only hearing ear. METHODS: A retrospective study was conducted in three patients with AN in the only hearing ear. Ipsilateral cochlear implantation (CI) was performed in case 1 and contralateral CI was performed in case 2 without tumor resection. In case 3, CI was performed 6 months after tumor removal by the retrosigmoid approach. Dynamic changes in the audiological tests was recorded regularly...
June 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27340257/treatment-of-foot-and-ankle-neuroma-pain-with-processed-nerve-allografts
#20
Jason M Souza, Chad A Purnell, Jennifer E Cheesborough, Armen S Kelikian, Gregory A Dumanian
BACKGROUND: Localized nerve pain in the foot and ankle can be a chronic source of disability after trauma and has been identified as the most common complication following operative interventions in the foot and ankle. The superficial location of the injured nerves and lack of suitable tissue for nerve implantation make this pain refractory to conventional methods of neuroma management. We describe a novel strategy for management using processed nerve allografts to bridge nerve gaps created by resection of both end neuromas and neuromas-in-continuity...
October 2016: Foot & Ankle International
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