keyword
MENU ▼
Read by QxMD icon Read
search

congshan

keyword
https://www.readbyqxmd.com/read/28709303/acoustic-multipole-sources-for-the-regularized-lattice-boltzmann-method-comparison-with-multiple-relaxation-time-models-in-the-inviscid-limit
#1
Congshan Zhuo, Pierre Sagaut
In this paper, a variant of the acoustic multipole source (AMS) method is proposed within the framework of the lattice Boltzmann method. A quadrupole term is directly included in the stress system (equilibrium momentum flux), and the dependency of the quadrupole source in the inviscid limit upon the fortuitous discretization error reported in the works of E. M. Viggen [Phys. Rev. E 87, 023306 (2013)PLEEE81539-375510.1103/PhysRevE.87.023306] is removed. The regularized lattice Boltzmann (RLB) method with this variant AMS method is presented for the 2D and 3D acoustic problems in the inviscid limit, and without loss of generality, the D3Q19 model is considered in this work...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28627588/il%C3%A2-22-expression-is-increased-variedly-in-the-initial-phase-onset-and-chronic-phase-of-a-pristane%C3%A2-induced-arthritis-rat-model
#2
Weikun Hou, Bo Wang, Yan Zhou, Ke Xu, Liesu Meng, Wenhua Zhu, Congshan Jiang, Peng Xu, Shemin Lu
The aim of the present study was to investigate the expression pattern of T helper (Th) 17 and Th22 cell-related factors in a pristane‑induced arthritis (PIA) rat model. PIA rats were divided into the initial phase group [day (D) 6 post‑pristane injection], the onset of clinical arthritis group (D12), the acute arthritis group (D26) and the chronic arthritis group (D70). Rats injected with saline alone were used as the control group. The mRNA expression levels of interleukin (IL)‑17A, IL‑17F, interferon (IFN)‑γ, IL‑22, IL‑22 receptor (R) 1, IL‑22 binding protein (BP) and RAR‑related orphan receptor α were examined in the spleen and/or synovium of the various phases of PIA rats by reverse transcription‑quantitative polymerase chain reaction analysis...
August 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28618527/implementation-of-dual-time-stepping-strategy-of-the-gas-kinetic-scheme-for-unsteady-flow-simulations
#3
Ji Li, Chengwen Zhong, Yong Wang, Congshan Zhuo
In our study, the dual time-stepping strategy of the gas-kinetic scheme is constructed and used for the simulation of unsteady flows. In comparison to the previous implicit gas-kinetic scheme, both the inviscid and viscous flux Jacobian are considered in our work, and the linear system of the pseudo-steady-state is solved by applying generalized minimal residual algorithm. The accuracy is validated by several numerical cases, the incompressible flow around blunt bodies (stationary circular cylinder and square cylinder), and the transonic buffet on the NACA0012 airfoil under hybrid mesh...
May 2017: Physical Review. E
https://www.readbyqxmd.com/read/28589555/common-and-distinctive-functions-of-the-hippo-effectors-taz-and-yap-in-skeletal-muscle-stem-cell-function
#4
Congshan Sun, Vanessa De Mello, Abdalla Mohamed, Huascar P Ortuste Quiroga, Amaya Garcia-Munoz, Abdullah Al Bloshi, Annie M Tremblay, Alexander von Kriegsheim, Elaina Collie-Duguid, Neil Vargesson, David Matallanas, Henning Wackerhage, Peter S Zammit
Hippo pathway downstream effectors Yap and Taz play key roles in cell proliferation and regeneration, regulating gene expression especially via Tead transcription factors. To investigate their role in skeletal muscle stem cells, we analyzed Taz in vivo and ex vivo in comparison with Yap. Small interfering RNA knockdown or retroviral-mediated expression of wild-type human or constitutively active TAZ mutants in satellite cells showed that TAZ promoted proliferation, a function shared with YAP. However, at later stages of myogenesis, TAZ also enhanced myogenic differentiation of myoblasts, whereas YAP inhibits such differentiation...
June 7, 2017: Stem Cells
https://www.readbyqxmd.com/read/27958403/rigorous-coupled-wave-analysis-equivalent-index-slab-method-for-analyzing-3d-angular-misalignment-in-interlayer-grating-couplers
#5
Congshan Wan, Thomas K Gaylord, Muhannad S Bakir
The interlayer waveguide grating coupling efficiencies under angular (rotational) misalignments are simulated using the 3D rigorous coupled-wave analysis (3D-RCWA) together with the RCWA equivalent-index-slab (RCWA-EIS) method. As examples of conical diffraction, rotations about the two coordinate axes, x and z, defined by the vectors [1 0 0] and [0 0 1], respectively, as well as an arbitrary axis, defined by the vector [2 2 1], are simulated for binary rectangular-groove gratings. The interlayer grating coupling efficiency is approximated by the product of the top- and bottom-grating diffraction efficiencies (DEs)...
December 10, 2016: Applied Optics
https://www.readbyqxmd.com/read/27940139/pristane-induces-autophagy-in-macrophages-promoting-a-stat1-irf1-tlr3-pathway-and-arthritis
#6
Wenhua Zhu, Jing Xu, Congshan Jiang, Bo Wang, Manman Geng, Xiaoying Wu, Nazim Hussain, Ning Gao, Yan Han, Dongmin Li, Xi Lan, Qilan Ning, Fujun Zhang, Rikard Holmdahl, Liesu Meng, Shemin Lu
Autophagy is involved in both innate and adaptive immune regulation. We propose that autophagy regulates activation of TLR3 in macrophages and is thereby essential for development of pristane-induced arthritis. We found that pristane treatment induced autophagy in macrophages in vitro and in vivo, in spleen cells from pristane injected rats. The induced autophagy was associated with STAT1 phosphorylation and expression of IRF1 and TLR3. Blocking the pristane activated autophagy by Wortmannin and Bafilomycin A1 or by RNAi of Becn1 led to a downregulation of the associated STAT1-IRF1-TLR3 pathway...
February 2017: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/27897164/hmgb1-mediated-autophagy-decreases-sensitivity-to-oxymatrine-in-sw982-human-synovial-sarcoma-cells
#7
Yongsong Cai, Peng Xu, Le Yang, Ke Xu, Jialin Zhu, Xiaoqing Wu, Congshan Jiang, Qiling Yuan, Bo Wang, Yuanbo Li, Yusheng Qiu
Oxymatrine (OMT) is a type of alkaloid extracted from a traditional Chinese medicinal herb, Sophora flavescens. Although the antitumor activities of OMT have been observed in various cancers, there are no reports regarding the effects of OMT on human synovial sarcoma. In the present study, we analyzed the antitumor activities of OMT in SW982 human synovial sarcoma cells and determine whether high mobility group box protein 1 (HMGB1)-mediated autophagy was associated with its therapeutic effects. We found that OMT exhibited antitumor activity in SW982 cells and facilitated increases in autophagy...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27887595/antimicrobial-stewardship-of-chinese-ministry-of-health-reduces-multidrug-resistant-organism-isolates-in-critically-ill-patients-a-pre-post-study-from-a-single-center
#8
Xudong Ma, Jianfeng Xie, Yi Yang, Fengmei Guo, Zhiwei Gao, Hua Shao, Yingzi Huang, Congshan Yang, Haibo Qiu
BACKGROUND: China's Ministry of Health (MOH) has established a policy about the antimicrobial stewardship. To date, the effects of this policy on multidrug-resistant organism (MDRO) in critically ill patients are unknown. METHODS: A pre-post study was conducted on intensive care unit (ICU) patients from June 2010 to May 2011 and from June 2012 to May 2013. Bacterial cultures were conducted at ICU admission and discharge. In June 2011, our hospital started to administer the antimicrobial stewardship program of Chinese MOH...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27828035/grating-design-for-interlayer-optical-interconnection-of-in-plane-waveguides-erratum
#9
Congshan Wan, Thomas K Gaylord, Muhannad S Bakir
Corrections to Eqs. (25) and (32) in our recent publication [Appl. Opt.55, 2601-2610 (2016).APOPAI0003-693510.1364/AO.55.002601] are presented in this erratum.
October 1, 2016: Applied Optics
https://www.readbyqxmd.com/read/27730520/construction-of-conveniently-screening-plko-1-trc-vector-tagged-with-turbogfp
#10
Jing Xu, Wenhua Zhu, Yuanxu Guo, Congshan Jiang, Nazim Hussain, Liesu Meng, Shemin Lu
The pLKO.1-TRC plasmid has been a popular and widely used vector due to its simple handling and stability. The huge RNAi database, a TRC library, has been established based on this vector. However, this plasmid only has a puromycin-resisted gene for selecting, which limits its application in microscopy and fluorescence-activated cell sorting (FACS). In the present work, PCR, restriction endonuclease digestion and molecular cloning techniques were used to insert the gene decoding green fluorescent protein (GFP) without changing the structure of original plasmid to extend its application...
February 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/27650867/microrna-137-inhibits-efnb2-expression-affected-by-a-genetic-variant-and-is-expressed-aberrantly-in-peripheral-blood-of-schizophrenia-patients
#11
Shanshan Wu, Rui Zhang, Fayi Nie, Xiaoli Wang, Congshan Jiang, Meng Liu, Robert K Valenzuela, Wanqing Liu, Yongyong Shi, Jie Ma
MicroRNAs (miRNAs) are a class of endogenous and non-coding single-stranded RNAs of approximately 22 nucleotides, many of which are evolutionarily conserved. Genome-wide association studies have identified a robust statistical association between the MIR137 gene and schizophrenia in Europeans, which was replicated in the Han Chinese population in a case-control study. In the previous study, we provided evidence for a significant association between the EFNB2 gene and schizophrenia in Han Chinese subjects. In the current study, we utilized computational analysis, vector construction of point mutations, luciferase reporter assays and gene expression assays including RT-qPCR and western blotting methods to investigate miR-137 directly targeting EFNB2 gene and explore the reversal effect of a genetic variant of SNP rs550067317 in the putative seed-pair region of EFNB2 3'-UTR...
October 2016: EBioMedicine
https://www.readbyqxmd.com/read/27505369/rcwa-eis-method-for-interlayer-grating-coupling
#12
Congshan Wan, Thomas K Gaylord, Muhannad S Bakir
The grating coupling efficiencies for interlayer connection (overlaid chips) were previously calculated using the new rigorous coupled-wave analysis equivalent-index-slab (RCWA-EIS) method. The chip-to-chip coupling efficiencies were determined for rectangular-groove (binary) gratings. In the present work, the search algorithms used in the RCWA-EIS method are optimized giving rise to improved definition of equivalent indices. Further, the versatility of the RCWA-EIS method is demonstrated by extending it to (nonbinary) parallelogramic gratings, sawtooth gratings, and volume gratings...
August 1, 2016: Applied Optics
https://www.readbyqxmd.com/read/27426724/toll-like-receptor-4-promotes-angiogenesis-in-pancreatic-cancer-via-pi3k-akt-signaling
#13
Yunliang Sun, Congshan Wu, Jianxia Ma, Yu Yang, Xiaohua Man, Hongyu Wu, Shude Li
Deregulation of Toll-like receptor 4 (TLR4) is closely associated with the progression of various types of cancers, but its role in pancreatic carcinogenesis is unclear. This study aimed to investigate the role of TLR4 in the angiogenesis of pancreatic cancer and the underlying molecular mechanisms. The culture supernatant (conditioned medium) of PANC-1 cells after appropriate treatment was used for the treatment of HUVECs. The proliferation, migration and tube formation of HUVECs were assessed by MTT, Transwell and Matrigel, respectively...
October 1, 2016: Experimental Cell Research
https://www.readbyqxmd.com/read/27184927/the-hippo-effector-taz-wwtr1-transforms-myoblasts-and-taz-abundance-is-associated-with-reduced-survival-in-embryonal-rhabdomyosarcoma
#14
Abdalla Mohamed, Congshan Sun, Vanessa De Mello, Joanna Selfe, Edoardo Missiaglia, Janet Shipley, Graeme I Murray, Pete S Zammit, Henning Wackerhage
The Hippo effector YAP has recently been identified as a potent driver of embryonal rhabdomyosarcoma (ERMS). Most reports suggest that the YAP paralogue TAZ (gene symbol WWTR1) functions as YAP but, in skeletal muscle, TAZ has been reported to promote myogenic differentiation, whereas YAP inhibits it. Here, we investigated whether TAZ is also a rhabdomyosarcoma oncogene or whether TAZ acts as a YAP antagonist. Immunostaining of rhabdomyosarcoma tissue microarrays revealed that TAZ is significantly associated with poor survival in ERMS...
September 2016: Journal of Pathology
https://www.readbyqxmd.com/read/27139662/grating-design-for-interlayer-optical-interconnection-of-in-plane-waveguides
#15
Congshan Wan, Thomas K Gaylord, Muhannad S Bakir
Interlayer grating-to-grating optical interconnect coupling efficiency is simulated and optimized using rigorous coupled-wave analysis (RCWA) for the case of binary rectangular-groove gratings. The "equivalent index slab (EIS)" concept is proposed to alleviate the numerical sensitivity problem inherent in the RCWA-leaky-wave approach, making the method applicable to any multilayer structure that has an arbitrary grating profile, large refractive-index differences, and a limited grating length. The method is easy to implement and computationally efficient and can provide optimal designs based on the system designer's need...
April 1, 2016: Applied Optics
https://www.readbyqxmd.com/read/27107686/trxr2-deficiencies-promote-chondrogenic-differentiation-and-induce-apoptosis-of-chondrocytes-through-mitochondrial-reactive-oxygen-species
#16
Jidong Yan, Jing Xu, Yao Fei, Congshan Jiang, Wenhua Zhu, Yan Han, Shemin Lu
Thioredoxin reductase 2 (TrxR2) is a selenium (Se) containing protein. Se deficiency is associated with an endemic osteoarthropathy characterized by impaired cartilage formation. It is unclear whether TrxR2 have roles in cartilage function. We examined the effects of TrxR2 on chondrogenic ATDC5 cells through shRNA-mediated gene silencing of TrxR2. We demonstrated TrxR2 deficiencies could enhance chondrogenic differentiation and apoptosis of ATDC5 cells. TrxR2 deficiencies increased accumulation of cartilage glycosaminoglycans (GAGs) and mineralization...
May 15, 2016: Experimental Cell Research
https://www.readbyqxmd.com/read/27075111/extracellular-microrna-21-and-microrna-26a-increase-in-body-fluids-from-rats-with-antigen-induced-pulmonary-inflammation-and-children-with-recurrent-wheezing
#17
Congshan Jiang, Hongchuan Yu, Qingzhu Sun, Wenhua Zhu, Jing Xu, Ning Gao, Rui Zhang, Li Liu, Xiaoying Wu, Xudong Yang, Liesu Meng, Shemin Lu
BACKGROUND: This study aims to find out whether extracellular miRNAs is implicated in recurrent childhood wheezing with asthmatic risk. METHODS: One hundred and forty children of Chinese Han population were recruited for this study. Plasma and intracellular miRNAs from children with recurrent wheezing and rats with antigen induced pulmonary inflammation (AIPI) were detected by using reverse transcription-quantitative PCR. Differential leukocytes in blood were automatically counted...
April 14, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27060415/regulation-of-ribosomal-rna-expression-across-the-lifespan-is-fine-tuned-by-maternal-diet-before-implantation
#18
Oleg Denisenko, Emma S Lucas, Congshan Sun, Adam J Watkins, Daniel Mar, Karol Bomsztyk, Tom P Fleming
Cells and organisms respond to nutrient deprivation by decreasing global rates of transcription, translation and DNA replication. To what extent such changes can be reversed is largely unknown. We examined the effect of maternal dietary restriction on RNA synthesis in the offspring. Low protein diet fed either throughout gestation or for the preimplantation period alone reduced cellular RNA content across fetal somatic tissues during challenge and increased it beyond controls in fetal and adult tissues after challenge release...
July 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/26951977/validation-of-reference-genes-for-quantitative-real-time-pcr-in-bovine-pbmcs-transformed-and-non-transformed-by-theileria-annulata
#19
Hongxi Zhao, Junlong Liu, Youquan Li, Congshan Yang, Shuaiyang Zhao, Juan Liu, Aihong Liu, Guangyuan Liu, Hong Yin, Guiquan Guan, Jianxun Luo
Theileria annulata is a tick-borne intracellular protozoan parasite that causes tropical theileriosis, a fatal bovine lymphoproliferative disease. The parasite predominantly invades bovine B lymphocytes and macrophages and induces host cell transformation by a mechanism that is not fully comprehended. Analysis of signaling pathways by quantitative real-time PCR (qPCR) could be a highly efficient means to understand this transformation mechanism. However, accurate analysis of qPCR data relies on selection of appropriate reference genes for normalization, yet few papers on T...
February 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/26408597/evaluating-the-babesia-bovis-infection-of-cattle-in-china-with-enzyme-linked-immunosorbent-assay-elisa
#20
Congshan Yang, Junlong Liu, Anyan Li, Youquan Li, Aihong Liu, Junren Xie, Guangyuan Liu, Hong Yin, Guiquan Guan, Jianxun Luo
Babesia bovis is an important pathogen of bovine babesiosis and causes serious constraints on the health and productivity of domestic cattle in the tropical and subtropical areas of the world. Aiming to clarify the prevalence of B. bovis in China, a total of 2,364 cattle serum samples were randomly collected from 45 different areas of 17 provinces in China. Antibodies against B. bovis were tested by enzyme-linked immunosorbent assay (ELISA) using a recombinant C-terminal antigen of B. bovis rhoptry-associated protein-1 (RAP-1) to evaluate the prevalence of B...
December 2015: Acta Parasitologica
keyword
keyword
107988
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"