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https://www.readbyqxmd.com/read/29890458/local-muscle-flaps-minimize-post-operative-wound-morbidity-in-patients-with-neoplastic-disease-of-the-spine
#1
Philipp Franck, Jaime L Bernstein, Leslie E Cohen, Roger Härtl, Ali A Baaj, Jason A Spector
OBJECTIVES: Patients with neoplastic disease involving the spine either from primary or metastatic disease present a unique challenge given these patients' frequent poor nutritional status at the time of surgery, the delivery of early post-operative chemotherapy or radiation, and placement of large amounts of hardware and avascular bone graft into a wound bed that is atrophic, previously operated or irradiated. As a result, wound morbidity has traditionally been high in this cohort of patients...
May 29, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29884480/predictors-of-serious-morbidity-and-mortality-after-endovascular-repair-of-aortoiliac-lesions
#2
A Taylor Thomas, I Michael Leitman
BACKGROUND: Endovascular approaches to aortoiliac disease are becoming increasingly frequent due to decreases in recovery time, bleeding, and discomfort. Despite this trend, little is known about the predictors of complications. This study was designed to identify risk factors for major 30-day morbidity and mortality after endovascular repair. METHODS: Data were derived from the 2015-2016 Participant User Files and Procedure Targeted databases of the American College of Surgeons National Surgical Quality Improvement Program...
June 5, 2018: Surgery
https://www.readbyqxmd.com/read/29868506/-staphylococcus-aureus-on-sinus-culture-is-associated-with-recurrence-of-chronic-rhinosinusitis-after-endoscopic-sinus-surgery
#3
Anastasios Maniakas, Marc-Henri Asmar, Axel E Renteria Flores, Smriti Nayan, Saud Alromaih, Leandra Mfuna Endam, Martin Y Desrosiers
Objectives: Identify whether identification of S. aureus on conventional culture is a predictor of success or failure after ESS followed by budesonide nasal irrigations (BUD) in chronic rhinosinusitis (CRS) patients at high risk of recurrence. Methodology: Prospective clinical trial including 116 patients from a tertiary care center at high-risk of disease recurrence following ESS+BUD. Blood samples, microbial swabs, and SNSS/SNOT-22 were taken on the day of surgery (Visit-1) and 4 months postoperatively (Visit-2)...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29800704/prophylactic-perioperative-dexamethasone-decreases-the-incidence-of-post-operative-c5-palsies-following-a-posterior-cervical-laminectomy-and-fusion
#4
Malcolm E Dombrowski, Alejandro Morales-Restrepo, Mitchell S Fourman, Nicholas Vaudreuil, Joon Y Lee
BACKGROUND CONTEXT: Post-operative C5 Palsy is a well-known complication of cervical decompression procedures. Studies have shown that posterior laminectomy and fusions confer the greatest risk of C5 palsy. Despite this, pharmacologic preventive measures remain unknown. We hypothesize that prophylactic perioperative dexamethasone will decrease the rate of post-operative C5 palsy in patients undergoing a multilevel posterior cervical laminectomy and fusion. PURPOSE: The purpose of this study was to assess the safety and efficacy of prophylactic perioperative dexamethasone in decreasing the rate of post-operative C5 palsy...
May 22, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29780908/rare-corneal-complication-following-selective-laser-trabeculoplasty
#5
Sarah Dougherty Wood, Angela Elam, Sayoko Moroi
Purpose: This case report describes two glaucoma patients who underwent selective laser trabeculoplasty (SLT) and developed a rare post-procedure corneal complication and subsequent permanent corneal distortions and reduced acuity. Observations: Both patients experienced early post-procedure corneal edema, reduced visual acuity, and pain. Each patient was treated with topical steroids with resolution of the edema, but each patient had irregular corneal astigmatism which was not present pre-operatively and did not resolve...
June 2018: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29718884/epidural-versus-intravenous-steroids-application-following-percutaneous-endoscopic-lumbar-discectomy
#6
Annan Hu, Xin Gu, Xiaofei Guan, Guoxin Fan, Shisheng He
Retrospectively study.The purpose of this study was to compare the effects of intraoperative epidural steroids and single dose intravenous steroids following a percutaneous endoscopic lumbar discectomy (PELD).Inflammatory irritation of dorsal root ganglia or sensory nerve roots may cause postoperative pain. Epidural steroids have been applied after a lumbar discectomy for more than 20 years. Epidural steroid application after a PELD is easier to perform and safer because the operations are under observation of the scope...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29680860/preservation-of-hearing-following-cochlear-implantation-using-different-steroid-therapy-regimens-a-prospective-clinical-study
#7
Magdalena Beata Skarżyńska, Piotr Henryk Skarżyński, Bartłomiej Król, Magdalena Kozieł, Kamila Osińska, Elżbieta Gos, Henryk Skarżyński
BACKGROUND A prospective clinical study was conducted to assess different regimens of steroid therapy and preservation of hearing following cochlear implantation. MATERIAL AND METHODS Study participants were ≥18 years-of-age, with a cochlear duct length ≥27.1 mm measured by computed tomography (CT), with hearing sound levels in the range of 10-120 decibels (dB) and sound frequencies of 125-250 hertz (Hz); sound levels of 35-120 dB and frequencies of 500-1,000 Hz; sound levels of 75-120 dB and frequencies of 2,000-8,000 Hz...
April 22, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29573263/effect-of-pre-operative-methylprednisolone-on-orthostatic-hypotension-during-early-mobilization-after-total-hip-arthroplasty
#8
V Lindberg-Larsen, P B Petersen, Ø Jans, T Beck, H Kehlet
BACKGROUND: Orthostatic hypotension (OH) and intolerance (OI) are common after total hip arthroplasty (THA) and may delay early mobilization. The pathology of OH and OI includes a dysregulated post-operative vasopressor response, by a hitherto unknown mechanism. We hypothesized that OI could be related to the inflammatory stress response which is inhibited by steroid administration. Consequently, this study evaluated the effect of a pre-operative high-dose methylprednisolone on OH and OI early after THA...
March 24, 2018: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/29550914/hip-osteonecroses-treated-with-calcium-sulfate-calcium-phosphate-bone-graft-substitute-have-different-results-according-to-the-cause-of-osteonecrosis-alcohol-abuse-or-corticosteroid-induced
#9
Andrzej Sionek, Adam Czwojdziński, Jacek Kowalczewski, Tomasz Okoń, Dariusz Marczak, Marcin Sibiński, Marcin Złotorowicz, Jarosław Czubak
INTRODUCTION: The aim of the study was to assess the factors influencing the final results of treatment of the femoral head osteonecrosis (ONFH) with core decompression and bone substitute grafting. The special interest was focused on comparison between alcohol- and steroid-induced ONFHs. MATERIAL AND METHODS: In this prospective study, a total of 53 patients (58 hips) in the mean age of 35.5 years were included: 29 had a history of alcohol use (32 hips) and 24 of steroid use (26 hips)...
March 17, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29547626/clinical-management-and-outcomes-of-patients-with-hermansky-pudlak-syndrome-pulmonary-fibrosis-evaluated-for-lung-transplantation
#10
Souheil El-Chemaly, Kevin J O'Brien, Steven D Nathan, Gerald L Weinhouse, Hilary J Goldberg, Jean M Connors, Ye Cui, Todd L Astor, Philip C Camp, Ivan O Rosas, Merte Lemma, Vladislav Speransky, Melissa A Merideth, William A Gahl, Bernadette R Gochuico
Pulmonary fibrosis is a progressive, fatal manifestation of Hermansky-Pudlak syndrome (HPS). Some patients with advanced HPS pulmonary fibrosis undergo lung transplantation despite their disease-associated bleeding tendency; others die while awaiting donor organs. The objective of this study is to determine the clinical management and outcomes of a cohort with advanced HPS pulmonary fibrosis who were evaluated for lung transplantation. Six patients with HPS-1 pulmonary fibrosis were evaluated at the National Institutes of Health Clinical Center and one of two regional lung transplant centers...
2018: PloS One
https://www.readbyqxmd.com/read/29536345/the-safety-of-magnetic-resonance-imaging-guided-laser-interstitial-thermal-therapy-for-cerebral-radiation-necrosis
#11
Richard Rammo, Karam Asmaro, Lonni Schultz, Lisa Scarpace, Salim Siddiqui, Tobias Walbert, Steven Kalkanis, Ian Lee
Cerebral radiation necrosis (CRN) is a known complication of radiation therapy. Treatment options are limited and include steroids, bevacizumab, and surgery. This study seeks to determine the safety of laser interstitial thermal therapy (LITT) for CRN and identify the pattern of post-ablation volume change over time. Patients undergoing LITT for tumor treatment at Henry Ford Hospital between November 2013 and January 2016 with biopsy-confirmed CRN were prospectively collected and retrospectively reviewed with attention to ablation volume, survival, demographic data, steroid dose, and complications...
March 13, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29506394/rolled-tendon-allograft-interposition-arthroplasty-for-salvage-surgery-of-the-hallux-metatarsophalangeal-joint
#12
Danielle Thomas, David Thordarson
BACKGROUND: Hallux rigidus is a common osteoarthritic disease of the first metatarsophalangeal joint (MTPJ). Few salvage treatment options exist that preserve motion for patients who have failed an initial procedure and who are not amenable to fusion, typically patients who are active or who would like to wear high heels. Allograft tendon interpositional arthroplasty is an unconventional salvage treatment option that may preserve motion and prevent bone loss. METHODS: A retrospective chart review is reported of 19 patients who failed previous procedures and refused fusion who underwent allograft tendon interpositional arthroplasty of the hallux MTPJ by a single surgeon between 2012 and 2015...
April 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29483370/outcomes-in-morbidly-obese-adolescent-patients-undergoing-laparoscopic-sleeve-gastrectomy-in-the-indian-subcontinent-a-retrospective-review
#13
Kirit Arumalla, Vitish Singla, Sandeep Aggarwal, Harshit Garg, Ritesh Goel, Varidh Katiyar
Introduction: There is a worldwide increase in the prevalence of obesity among the adolescent population in India from 16.3% in 2001 to 19.3% in 2010. Recent evidence suggests that bariatric surgery leads to resolution of comorbidities and associated long-term complications in adolescent patients with morbid obesity. Aim: The aim of this study is to determine the impact of bariatric surgery on the weight loss and comorbidities of morbidly obese adolescents. Materials and Methods: A retrospective review of the data of 10 adolescent patients, who underwent Laparoscopic Sleeve Gastrectomy at our institute (tertiary care hospital), from July 2009 to July 2016 was carried out...
February 27, 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29411291/post-liver-transplantation-diabetes-mellitus-a-review-of-relevance-and-approach-to-treatment
#14
REVIEW
Maria J Peláez-Jaramillo, Allison A Cárdenas-Mojica, Paula V Gaete, Carlos O Mendivil
Post-liver transplantation diabetes mellitus (PLTDM) develops in up to 30% of liver transplant recipients and is associated with increased risk of mortality and multiple morbid outcomes. PLTDM is a multicausal disorder, but the main risk factor is the use of immunosuppressive agents of the calcineurin inhibitor (CNI) family (tacrolimus and cyclosporine). Additional factors, such as pre-transplant overweight, nonalcoholic steatohepatitis and hepatitis C virus infection, may further increase risk of developing PLTDM...
April 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29403152/adrenocortical-carcinoma-characterized-by-gynecomastia-a-case-report
#15
Takako Takeuchi, Yuko Yoto, Akira Ishii, Takeshi Tsugawa, Masaki Yamamoto, Tsukasa Hori, Hotaka Kamasaki, Kazutaka Nogami, Takanori Oda, Akihiro Nui, Sachiko Kimura, Takuya Yamagishi, Keiko Homma, Tomonobu Hasegawa, Maki Fukami, Yoko Watanabe, Hidehiko Sasamoto, Hiroyuki Tsutsumi
We present a 4-yr-old boy with adrenocortical carcinoma (ACC), diagnosed due to the appearance of gynecomastia as the presenting symptom. Six months prior to admission, an acute growth spurt along with the development of bilateral breast swelling was observed. He did not present any features of virilization, including enlargement of the testes, increase in testis volume, and penis size. Laboratory investigations showed gonadotropin-independent hypergonadism, with low LH/ FSH levels and elevated estradiol/testosterone levels...
2018: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/29394550/-a-patient-with-basaloid-carcinoma-of-the-esophagus-removed-surgically-after-pre-operative-chemotherapy-who-developed-ttp-during-post-operative-chemotherapy
#16
Akemi Watanabe, Hiroyuki Fukunari, Yousuke Kawai, Makoto Aoki, Satoshi Saito, Yuya Umebayashi, Kenji Shitara, Tetsuji Hayashi, Gen Watanabe, Hiroshi Ajioka
A 63-year-old man presented with the chief complaint of an unpleasant feeling in the chest after a meal.Esophagogastroduodenoscopy revealed interminglement of ulcer infiltration type lesions and protruding lesions in the lower esophagus.A large type 1 protruding lesion was located mainly in the esophagogastric junction(EGJ)and it progressed towards the stomach.A hypertrophic and protruding lesion on the lower esophageal wall and a 6 cm tumor in the major axis of the fornix were observed on thoracic and abdominal CT, and an endocrine cell carcinoma or basaloid carcinoma were suggested after biopsy...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29389252/risk-factors-and-predictive-model-development-of-thirty-day-post-operative-surgical-site-infection-in-the-veterans-administration-surgical-population
#17
Xinli Li, William Nylander, Tracy Smith, Soonhee Han, William Gunnar
BACKGROUND: Surgical site infection (SSI) complicates approximately 2% of surgeries in the Veterans Affairs (VA) hospitals. Surgical site infections are responsible for increased morbidity, length of hospital stay, cost, and mortality. Surgical site infection can be minimized by modifying risk factors. In this study, we identified risk factors and developed accurate predictive surgical specialty-specific SSI risk prediction models for the Veterans Health Administration (VHA) surgery population...
April 2018: Surgical Infections
https://www.readbyqxmd.com/read/29356715/postoperative-inflammation-after-endoscopic-cyclophotocoagulation-racial-distribution-and-effect-on-outcomes
#18
Anna M Edmiston, Jeffrey R SooHoo, Leonard K Seibold, Malik Y Kahook, Alan G Palestine, Mina B Pantcheva
PURPOSE: To assess the prevalence of postoperative anterior chamber reaction or persistent anterior uveitis (PAU) by race and its effect on intraocular pressure (IOP) and visual acuity (VA) after combined phacoemulsification and endoscopic cyclophotocoagulation (ECP) in primary open-angle glaucoma. PATIENTS AND METHODS: A retrospective analysis of all patients with primary open-angle glaucoma who underwent combined phacoemulsification cataract extraction with ECP from January 1, 2007 to October 31, 2015...
March 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29300932/endometrial-stromal-cell-attachment-and-matrix-homeostasis-in-abdominal-wall-endometriomas
#19
Hiroko Itoh, Haruta Mogami, Laurice Bou Nemer, Larry Word, David Rogers, Rodney Miller, R Ann Word
STUDY QUESTION: How does progesterone alter matrix remodeling in abdominal wall endometriomas compared with normal endometrium? SUMMARY ANSWER: Progesterone may prevent attachment of endometrial cells to the abdominal wall, but does not ameliorate abnormal stromal cell responses of abdominal wall endometriomas. WHAT IS KNOWN ALREADY: Menstruation is a tightly orchestrated physiologic event in which steroid hormones and inflammatory cells cooperatively initiate shedding of the endometrium...
February 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29277083/manipulation-under-anaesthesia-and-steroid-injection-for-pain-and-stiffness-after-surgery-to-the-first-metatarsophalangeal-joint
#20
Sanil Ajwani, Cezary Kocialkowski, Rebecca Hill, Nasser Kurdy
AIM: To determine the effectiveness of manipulation under anaesthesia and local steroid injection to treat stiffness of the first metatarsophalangeal joint following surgery for hallux rigidus or hallux valgus. METHODS: Patients were identified who had undergone surgery for hallux rigidus or hallux valgus and subsequently were treated with manipulation and steroid injection for stiffness of their joint. Patient records were reviewed to determine the range of movement of the joint pre-operatively, immediately following the procedure and at subsequent follow up...
March 2018: Foot
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