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https://www.readbyqxmd.com/read/28338301/analgesia-for-patients-undergoing-shockwave-lithotripsy-for-urinary-stones-a-systematic-review-and-meta-analysis
#1
Omar M Aboumarzouk, Rami Hasan, Ali Tasleem, Martin Mariappan, Rachael Hutton, John Fitzpatrick, Laura Beatty, Gareth E Jones, Tarik Amer
BACKGROUND: Shock wave lithotripsy (SWL) is the first line treatment modality for a significant proportion of patients with upper urinary tracts stones. Simple analgesics, opioids and non-steroidal anti-inflammatory drugs (NSAIDs) are all suitable agents but the relative efficacy and tolerability of these agents is uncertain. OBJECTIVES: To determine the efficacy of the different types of analgesics used for the control of pain during SWL for urinary stones. MATERIALS AND METHODS: We searched the Cochrane Renal Group's Specialised Register, MEDLINE, EMBASE and also hand-searched reference lists of relevant articles (Figure-1)...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28219426/pseudophakic-cystoid-macular-edema-prevention-and-risk-factors-prospective-study-with-adjunctive-once-daily-topical-nepafenac-0-3-versus-placebo
#2
RANDOMIZED CONTROLLED TRIAL
Sean McCafferty, April Harris, Corin Kew, Tala Kassm, Lisa Lane, Jason Levine, Meisha Raven
BACKGROUND: Define the effectiveness of a topical non-steroidal anti-inflammatory drug (NSAID) added to topical steroid use after uncomplicated phacoemulsification for the prevention of pseudophakic cystoid macular edema (PCME) using a prospective, randomized, double-masked, placebo-controlled clinical study. METHODS: Eyes (1000) were randomized to placebo (497) or nepafenac 0.3% (503) used once daily, post-operatively for 5 weeks at two ophthalmology clinics. Diagnosis of PCME was made by clinical, ocular coherence tomography (OCT), and with fluorescein angiography confirmation...
February 20, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28169009/role-of-adenoidectomy-in-chronic-nasal-obstruction-after-nasal-steroid-therapy-failure
#3
Peter J Ciolek, Allen Xu, Samantha Anne, Katie Geelan-Hansen
OBJECTIVE: To identify clinical characteristics of pediatric patients that failed nasal steroid therapy for management of chronic nasal obstruction and to evaluate the efficacy of adenoidectomy in this subset of patients. DESIGN: Retrospective chart review. SETTING: Tertiary care academic center. SUBJECTS: Analysis was performed on children that underwent adenoidectomy between 2011 and 2015 for chronic nasal obstruction refractory to nasal steroids...
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27864707/impact-of-operative-length-on-post-operative-complications-in-meningioma-surgery-a-nsqip-analysis
#4
Aditya V Karhade, Luis Fandino, Saksham Gupta, David J Cote, Julian B Iorgulescu, Marike L Broekman, Linda S Aglio, Ian F Dunn, Timothy R Smith
Many studies have implicated operative length as a predictor of post-operative complications, including venous thromboembolism [deep vein thrombosis (DVT) and pulmonary embolism (PE)]. We analyzed the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) database from 2006 to 2014, to evaluate whether length of operation had a statistically significant effect on post-operative complications in patients undergoing surgical resection of meningioma. Patients were included for this study if they had a post-operative diagnosis of meningioma...
January 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27827521/ultrasonography-for-neuraxial-blocks-a-review-of-the-evidence
#5
Maria F Elgueta, Silvia Duong, Roderick J Finlayson, De Q. Tran
INTRODUCTION: This narrative review summarizes the evidence derived from randomized controlled trials (RCTs) pertaining to the use of adjunctive ultrasonography (US) for neuraxial blocks. EVIDENCE ACQUISITION: The literature search was conducted using the MEDLINE, EMBASE and PUBMED databases. For the MEDLINE and EMBASE searches, the MESH terms "ultrasonography" and key word "ultrasound" were queried; using the operator "and", they were combined with the MESH terms "neuraxial block", "epidural anesthesia", "epidural analgesia", "spinal anesthesia", "spinal analgesia", "intrathecal anesthesia", "intrathecal analgesia", "caudal anesthesia", and "caudal analgesia"...
November 9, 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/27815992/contralateral-hearing-loss-and-facial-palsy-in-an-operated-case-of-vestibular-schwannoma-case-report
#6
Abhijit Warade, Pawan Chawla, Anshu Warade, Ketan Desai
INTRODUCTION: Contralateral ear hearing loss (CHL) is an extremely rare but a potentially devastating complication in a patient with already compromised hearing due to a Vestibular schwannoma (VS). Our patient had CHL accompanied by contralateral facial palsy. Our case is only the second case reported in literature to the best of our knowledge. PRESENTATION OF CASE: A 55-year elderly male presented with right sided sensorineural hearing loss, cerebellar signs and Grade II House & Brackmann (H&B) facial nerve weakness for last1-year...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27777051/patient-reported-outcomes-after-lumbar-epidural-steroid-injection-for-degenerative-spine-disease-in-depressed-versus-non-depressed-patients
#7
Elliott J Kim, Silky Chotai, David P Stonko, Joseph B Wick, Byron J Schneider, Matthew J McGirt, Clint J Devin
BACKGROUND CONTEXT: Medical interventional modalities such as lumbar epidural steroid injections (LESIs) are often used in the setting of lumbar spine disorders where other conservative measures have failed. Concomitant depression can lead to worse outcomes in lumbar spine pathology. A number of studies have demonstrated an association between preoperative depression and poor outcomes following surgery, but the effect of depression on outcomes following medical interventional modalities is poorly understood...
October 21, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27746900/recent-advances-in-the-surgical-management-of-rhinosinusitis
#8
REVIEW
Alexandria F Jaksha, Erik K Weitzel, Adrienne M Laury
Rhinosinusitis affects a significant portion of the US population, and its management imposes a substantial burden on the healthcare system. The treatment of chronic rhinosinusitis includes initial medical management prior to consideration of surgical intervention. However, if surgery does become necessary, several factors must be considered in order to optimize outcomes. This review evaluates surgical patient selection, perioperative medical management, and the extent of operative intervention, with the goal of improving surgical results, decreasing the need for revision surgery, and enhancing the patient's quality of life...
2016: F1000Research
https://www.readbyqxmd.com/read/27666330/potentially-modifiable-risk-factors-for-atrial-fibrillation-following-lung-resection-surgery-a-retrospective-cohort-study
#9
S H Lee, H J Ahn, S M Yeon, M Yang, J A Kim, D M Jung, J H Park
Atrial fibrillation is the most frequent arrhythmia after thoracic surgery and is associated with increased hospital costs, morbidity and mortality. In this study, we aimed to identify potentially modifiable risk factors for postoperative atrial fibrillation following lung resection surgery and to suggest possible measures to reduce risk. We retrospectively reviewed the medical records of 4731 patients who underwent lobectomy or more major lung resection over a 6-year period. Patients who developed atrial fibrillation postoperatively and required treatment were included in the postoperative atrial fibrillation group, while the remaining patients were assigned to the non-postoperative atrial fibrillation group...
December 2016: Anaesthesia
https://www.readbyqxmd.com/read/27625236/an-algorithmic-approach-for-clinical-management-of-low-back-pain
#10
V V Ramesh Chandra, B C M Prasad, C Krishna Mohan, T C Kalawat, V Satyanarayana, A Y Lakshmi
BACKGROUND: Low back pain is caused by a variety of conditions. When conventional imaging failed, single-photon emission computed tomography (SPECT) was superior to scintigraphy in identifying the pathology. Injection therapies are often helpful in treating the pathology. AIM: To determine the cause of chronic low backache in individuals with normal conventional imaging (radiographs, computed tomography and magnetic resonance imaging), to determine the specific pathology using scintigraphic studies and diagnostic blocks; and, to treat the individuals with various spinal injection techniques and determine their efficacy...
September 2016: Neurology India
https://www.readbyqxmd.com/read/27619980/surgical-management-of-posterior-fossa-metastases
#11
Geraint J Sunderland, Michael D Jenkinson, Rasheed Zakaria
The diagnosis of brain metastases is associated with a poor prognosis reflecting uncontrolled primary disease that has spread to the relative sanctuary of the central nervous system. 20 % of brain metastases occur in the posterior fossa and are associated with significant morbidity. The risk of acute hydrocephalus and potential for sudden death means these metastases are often dealt with as emergency cases. This approach means a full pre-operative assessment and staging of underlying disease may be neglected and a proportion of patients undergo comparatively high risk surgery with little or no survival benefit...
December 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27582674/a-cluster-of-presumed-noninfectious-endophthalmitis-after-intravitreal-injection-of-bevacizumab-long-term-follow-up
#12
Federico Ricci, Antonio Calabrese, Cecilia De Felici, Filippo Missiroli, Marco Pileri, Federico Regine
PURPOSE: To report the outcome of 5 consecutive cases of presumed, noninfectious endopththalmitis following intravitreal injection of bevacizumab (IVB). METHODS: Ten pre-loaded syringes of bevacizumab (1.25 mg/50 µL) furnished by a compounding pharmacy were injected intravitreally. Treatments were performed in the operating room by the same surgeon on 2 consecutive days. RESULTS: Of 10 eyes, 5 showed moderate to severe ocular inflammation within a few days of injection...
2016: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/27490717/mechanisms-of-triple-whammy-acute-kidney-injury
#13
Laura Prieto-García, Miguel Pericacho, Sandra M Sancho-Martínez, Ángel Sánchez, Carlos Martínez-Salgado, José Miguel López-Novoa, Francisco J López-Hernández
Pre-renal acute kidney injury (AKI) results from glomerular haemodynamic alterations leading to reduced glomerular filtration rate (GFR) with no parenchymal compromise. Renin-angiotensin system inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor antagonists (ARAs), non-steroidal anti-inflammatory drugs (NSAIDs) and diuretics, are highly prescribed drugs that are frequently administered together. Double and triple associations have been correlated with increased pre-renal AKI incidence, termed "double whammy" and "triple whammy", respectively...
November 2016: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27484082/a-phase-iii-multi-centre-double-masked-randomised-controlled-trial-of-adjunctive-intraocular-and-peri-ocular-steroid-triamcinolone-acetonide-versus-standard-treatment-in-eyes-undergoing-vitreoretinal-surgery-for-open-globe-trauma-ascot-statistical-analysis
#14
Jessica W Lo, Catey Bunce, David Charteris, Philip Banerjee, Rachel Phillips, Victoria R Cornelius
BACKGROUND: Open globe ocular trauma complicated by intraocular scarring (proliferative vitreoretinopathy) is a relatively rare, blinding, but potentially treatable condition for which, at present, surgery is often unsatisfactory and visual results frequently poor. To date, no pharmacological adjuncts to surgery have been proven to be effective. The aim of the Adjunctive Steroid Combination in Ocular Trauma (ASCOT) randomised controlled trial is to determine whether adjunctive steroid (triamcinolone acetonide), given at the time of surgery, can improve the outcome of vitreoretinal surgery in patients with open globe ocular trauma...
2016: Trials
https://www.readbyqxmd.com/read/27449500/adjunctive-intraocular-and-peri-ocular-steroid-triamcinolone-acetonide-versus-standard-treatment-in-eyes-undergoing-vitreoretinal-surgery-for-open-globe-trauma-ascot-study-protocol-for-a-phase-iii-multi-centre-double-masked-randomised-controlled-trial
#15
Philip J Banerjee, Victoria R Cornelius, Rachel Phillips, Jessica W Lo, Catey Bunce, Joanna Kelly, Caroline Murphy, Rhiannon Tudor Edwards, Elizabeth L Robertson, David G Charteris
BACKGROUND: Eyes sustaining open globe trauma are at high risk of severe visual impairment. Ocular injuries which result in visual loss invariably affect the posterior segment of the eye, and prevention of visual loss involves posterior segment (vitreoretinal) surgery. Despite improvements in vitreoretinal surgical techniques, outcomes in these patients remain unsatisfactory, and development of the intraocular scarring response proliferative vitreoretinopathy is the leading cause. Proliferative vitreoretinopathy is the most common cause of recurrent retinal detachment in these eyes; it is reported to occur in up to 45 % of cases...
2016: Trials
https://www.readbyqxmd.com/read/27441075/symptomatic-ovarian-steroid-cell-tumor-not-otherwise-specified-in-a-post-menopausal-woman
#16
Neha Sood, Kaniksha Desai, Ana-Maria Chindris, Jason Lewis, Tri A Dinh
Steroid cell tumor not otherwise specified (NOS) is a rare subtype of sex cord stromal tumor of the ovary and contributes less than 0.1% of all ovarian neoplasms. The majority of tumors occur in pre-menopausal women (mean age: 43 years), in which 56-77% of patients present with virilization due to excess testosterone. An 80-year-old woman with worsening alopecia and excessive growth of coarse hair on abdomen and genital area was found to have elevated serum testosterone level (462 ng/mL). Radiologic studies were consistent with bilateral adrenal adenomas...
June 28, 2016: Rare Tumors
https://www.readbyqxmd.com/read/27403384/investigating-the-impacts-of-preoperative-steroid-treatment-on-tumor-necrosis-factor-alpha-and-duration-of-extubation-time-underwent-ventricular-septal-defect-surgery
#17
H Hakan Poyrazoğlu, Zeynel Duman, Şerafettin Demir, M Kemal Avşar, Atakan Atalay, Bahattin Çiftçi, İhsan Bayraktar, Funda Tor
BACKGROUND: Cardiopulmonary bypass is known to cause inflammatory events. Inflammation occurs due to many known important biological processes. Numerous mechanisms are known to be responsible for the development of inflammatory processes. Currently, there are many defined mediators as a tumor necrosis factor-α (TNF-α) playing an active role in this process. AIMS: This research was to investigate the effects of pre-operative steroid use on inflammatory mediator TNF-α and on time to extubation postoperatively in ventricular septal defect patients undergoing cardiopulmonary bypass surgery...
March 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27235739/the-impact-of-biological-sex-and-sex-hormones-on-cognition-in-a-rat-model-of-early-pre-motor-parkinson-s-disease
#18
Erika Betancourt, Jonathan Wachtel, Michalis Michaelos, Michael Haggerty, Jessica Conforti, Mary F Kritzer
Parkinson's disease (PD) is well known for motor deficits such as bradykinesia. However, patients often experience additional deficits in working memory, behavioral selection, decision-making and other executive functions. Like other features of PD, the incidence and severity of these cognitive symptoms differ in males and females. However, preclinical models have not been used to systematically investigate the roles that sex or sex hormones may play in these complex signs. To address this, we used a Barnes maze spatial memory paradigm to compare the effects of a bilateral nigrostriatal dopamine lesion model of early PD on cognitive behaviors in adult male and female rats and in adult male rats that were gonadectomized or gonadectomized and supplemented with testosterone or estradiol...
May 26, 2016: Neuroscience
https://www.readbyqxmd.com/read/27215013/external-drainage-for-exudative-retinal-detachment-secondary-to-central-serous-chorioretinopathy
#19
Sailaja Bondalapati, Avinash Pathengay, Jay Chhablani
BACKGROUND: To report the outcomes of external drainage of subretinal fluid (SRF) in exudative retinal detachment secondary to central serous chorioretinopathy (CSCR). METHODS: Retrospective observational analysis of six eyes with exudative retinal detachment secondary to CSCR who underwent external drainage of SRF between 2004 and 2014 was performed. Collected data included demographics, steroid usage, surgical details, and visual acuity preoperatively and postoperative visual acuity and clinical examination data were collected...
December 2015: Eye Science
https://www.readbyqxmd.com/read/27134449/a-comparative-evaluation-of-the-effect-of-diclofenac-sodium-with-and-without-per-orally-administered-methylprednisolone-on-the-sequelae-of-impacted-mandibular-third-molar-removal-a-cohort-randomized-double-blind-clinical-trial
#20
Deepti V Prashar, Deepti Pahwa, Vimal Kalia, Govind Jindal, Rupinder Kaur
AIM AND OBJECTIVES: This study evaluated the efficacy of oral methylprednisolone and diclofenac sodium on post-operative sequelae after third molar surgery. SETTINGS AND DESIGN: A randomized double-blind clinical trial was conducted (with institutional and university approval for dissertation) to evaluate the effect of methylprednisolone with diclofenac sodium (group A) as compared with diclofenac sodium and placebo (group B) on three variables: Pain, swelling and trismus, after third molar surgery...
January 2016: Indian Journal of Dentistry
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