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https://www.readbyqxmd.com/read/15467500/sorbents-in-the-treatment-of-renal-failure
#1
REVIEW
J F Winchester, J A Salsberg
Standard renal replacement therapy in acute renal failure (ARF) and end-stage renal disease (ESRD) is based on membrane technology. The transition from natural cellulosic membranes to synthetic membranes has not been associated with improvement in mortality rates. Modifications of dialysis with continuous arteriovenous hemofiltration and hemodiafiltration to remove middle molecular weight toxins, low molecular weight proteins and peptides (LMWP) and cytokines involved in inflammation appear to have reached their limits...
September 2004: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/14732814/sorbents-in-acute-renal-failure-and-end-stage-renal-disease-middle-molecule-and-cytokine-removal
#2
James F Winchester, Jeffrey Silberzweig, Claudio Ronco, Viktoria Kuntsevich, Daniel Levine, Tom Parker, John A Kellum, Jamie A Salsberg, Peter Quartararo, Nathan W Levin
Renal replacement therapy in acute renal failure (ARF) and chronic renal failure (end-stage renal disease; ESRD) has been based on the use of modifications of dialysis (continuous arteriovenous hemofiltration and hemodiafiltration) to remove middle-molecular-weight toxins, consisting of low-molecular-weight proteins and peptides (LMWP) and cytokines involved in inflammation. High-flux dialyzers are not efficient at removing LMWP, and for this reason, sorbents have been studied to augment or replace dialysis...
2004: Blood Purification
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