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https://www.readbyqxmd.com/read/28213144/modeling-and-validating-hl7-fhir-profiles-using-semantic-web-shape-expressions-shex
#1
Harold R Solbrig, Eric Prud'hommeaux, Grahame Grieve, Lloyd McKenzie, Joshua C Mandel, Deepak K Sharma, Guoqian Jiang
BACKGROUND: HL7 Fast Healthcare Interoperability Resources (FHIR) is an emerging open standard for the exchange of electronic healthcare information. FHIR resources are defined in a specialized modeling language. FHIR instances can currently be represented in either XML or JSON. The FHIR and Semantic Web communities are developing a third FHIR instance representation format in Resource Description Framework (RDF). Shape Expressions (ShEx), a formal RDF data constraint language, is a candidate for describing and validating the FHIR RDF representation...
February 14, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28212602/happi-2-a-comprehensive-and-high-quality-map-of-human-annotated-and-predicted-protein-interactions
#2
Jake Y Chen, Ragini Pandey, Thanh M Nguyen
BACKGROUND: Human protein-protein interaction (PPI) data is essential to network and systems biology studies. PPI data can help biochemists hypothesize how proteins form complexes by binding to each other, how extracellular signals propagate through post-translational modification of de-activated signaling molecules, and how chemical reactions are coupled by enzymes involved in a complex biological process. Our capability to develop good public database resources for human PPI data has a direct impact on the quality of future research on genome biology and medicine...
February 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28212462/climate-change-contaminant-interactions-in-marine-food-webs-towards-a-conceptual-framework
#3
Juan José Alava, William W L Cheung, Peter S Ross, Rashid U Sumaila
Climate change is reshaping the way in which contaminants move through the global environment, in large part by changing the chemistry of the oceans and affecting the physiology, health and feeding ecology of marine biota. Climate change-associated impacts on structure and function of marine food webs, with consequent changes in contaminant transport, fate and effects, is likely to have significant repercussions to those human populations that rely on fisheries resources for food, recreation or culture. Published studies on climate change-contaminant interactions with a focus on food web bioaccumulation were systematically reviewed to explore how climate change and ocean acidification may impact contaminant levels in marine food webs...
February 17, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28211003/an-easy-to-build-low-budget-point-of-care-ultrasound-simulator-from-linux-to-a-web-based-solution
#4
Domagoj Damjanovic, Ulrich Goebel, Benedikt Fischer, Martin Huth, Hartmut Breger, Hartmut Buerkle, Axel Schmutz
BACKGROUND: Hands-on training in point-of-care ultrasound (POC-US) should ideally comprise bedside teaching, as well as simulated clinical scenarios. High-fidelity phantoms and portable ultrasound simulation systems are commercially available, however, at considerable costs. This limits their suitability for medical schools. A Linux-based software for Emergency Department Ultrasound Simulation (edus2TM) was developed by Kulyk and Olszynski in 2011. Its feasibility for POC-US education has been well-documented, and shows good acceptance...
December 2017: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/28208796/recent%C3%A2-trends%C3%A2-in%C3%A2-marine%C3%A2-phycotoxins%C3%A2-from%C3%A2-australian%C3%A2-coastal%C3%A2-waters
#5
Penelope Ajani, D Tim Harwood, Shauna A Murray
Phycotoxins, which are produced by harmful microalgae and bioaccumulate in the  marine food web, are of growing concern for Australia. These harmful algae pose a threat to  ecosystem and human health, as well as constraining the progress of aquaculture, one of the fastest  growing food sectors in the world. With better monitoring, advanced analytical skills and an  increase in microalgal expertise, many phycotoxins have been identified in Australian coastal  waters in recent years...
February 9, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28205600/non-reliance-of-metazoans-on-stromatolite-forming-microbial-mats-as-a-food-resource
#6
Gavin M Rishworth, Renzo Perissinotto, Matthew S Bird, Nadine A Strydom, Nasreen Peer, Nelson A F Miranda, Jacqueline L Raw
Grazing and burrowing organisms usually homogenise microalgal mats that form on benthic sediments of many aquatic ecosystems. In the absence of this disruption, microalgal mats can accrete laminated deposits (stromatolites). Stromatolites are rare in modern coastal ecosystems, but persist at locations where metazoans are largely excluded. This study aimed to assess the trophic structure at stromatolite locations where metazoans co-occur, to determine the grazing influence exerted by the metazoans on the stromatolite-forming microalgae (cyanobacteria and diatoms)...
February 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28203705/pln24nt-a-web-resource-for-plant-24-nt-sirna-producing-loci
#7
Qi Liu, Changjun Ding, Yanguang Chu, Weixi Zhang, Ganggang Guo, Jiafei Chen, Xiaohua Su
No abstract text is available yet for this article.
February 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28199920/family-burden-child-disability-and-the-adjustment-of-mothers-caring-for-children-with-epilepsy-role-of-social-support-and-coping
#8
Jeffrey M Carlson, Paul A Miller
PURPOSE: This study was designed to contribute to the existing research on the coping behaviors, social support, and mental health outcomes in parents of children with epilepsy in the United States. METHODS: Participants included 152, predominantly Caucasian (89.5%), married (78.9%) women (95.4%). Via a web-based interface, mothers completed questionnaires assessing the impact of their child's disability on their family (i.e., severity of their child's disability, family burden, and personal stress), social resources (i...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28198755/career-development-support-in-pediatric-critical-care-medicine-a-national-survey-of-fellows-and-junior-faculty
#9
Christina L Cifra, Shilpa S Balikai, Tanya D Murtha, Benson Hsu, Carley L Riley
OBJECTIVES: To determine the perceptions of current pediatric critical care medicine fellows and junior faculty regarding the extent and quality of career development support received during fellowship training. DESIGN: Web-based cross-sectional survey open from September to November 2015. SETTING: Accreditation Council for Graduate Medical Education-accredited pediatric critical care medicine fellowship programs. SUBJECTS: Pediatric critical care medicine fellows (second yr or higher) and junior faculty (within 5 yr of completing a pediatric critical care medicine fellowship program)...
February 14, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28194230/what-are-the-personal-and-professional-characteristics-that-distinguish-the-researchers-who-publish-in-high-and-low-impact-journals-a-multi-national-web-based-survey
#10
Carlos Eduardo Paiva, Raphael L C Araujo, Bianca Sakamoto Ribeiro Paiva, Cristiano de Pádua Souza, Flavio Mavignier Cárcano, Marina Moreira Costa, Sérgio Vicente Serrano, João Paulo Nogueira Lima
PURPOSE: This study identifies the personal and professional profiles of researchers with a greater potential to publish high-impact academic articles. METHOD: The study involved conducting an international survey of journal authors using a web-based questionnaire. The survey examined personal characteristics, funding, and the perceived barriers of research quality, work-life balance, and satisfaction and motivation in relation to career. The processes of manuscript writing and journal publication were measured using an online questionnaire that was developed for this study...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28193215/analysing-trends-and-forecasting-malaria-epidemics-in-madagascar-using-a-sentinel-surveillance-network-a-web-based-application
#11
Florian Girond, Laurence Randrianasolo, Lea Randriamampionona, Fanjasoa Rakotomanana, Milijaona Randrianarivelojosia, Maherisoa Ratsitorahina, Télesphore Yao Brou, Vincent Herbreteau, Morgan Mangeas, Sixte Zigiumugabe, Judith Hedje, Christophe Rogier, Patrice Piola
BACKGROUND: The use of a malaria early warning system (MEWS) to trigger prompt public health interventions is a key step in adding value to the epidemiological data routinely collected by sentinel surveillance systems. METHODS: This study describes a system using various epidemic thresholds and a forecasting component with the support of new technologies to improve the performance of a sentinel MEWS. Malaria-related data from 21 sentinel sites collected by Short Message Service are automatically analysed to detect malaria trends and malaria outbreak alerts with automated feedback reports...
February 13, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28193214/impacts-of-a-navigation-program-based-on-health-information-technology-for-patients-receiving-oral-anticancer-therapy-the-capri-randomized-controlled-trial
#12
Chloé Gervès-Pinquié, Fatima Daumas-Yatim, Benoît Lalloué, Anne Girault, Marie Ferrua, Aude Fourcade, François Lemare, Mario Dipalma, Etienne Minvielle
BACKGROUND: The emergence of oral delivery in cancer therapeutics is expected to result in an increased need for better coordination between all treatment stakeholders, mainly to ensure adequate treatment delivery to the patient. There is significant interest in the nurse navigation program's potential to improve transitions of care by improving communication between treatment stakeholders and by providing personalized organizational assistance to patients. The use of health information technology is another strategy aimed at improving cancer care coordination that can be combined with the NN program to improve remote patient follow-up...
February 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28192728/core-competency-requirements-among-extension-workers-in-peninsular-malaysia-use-of-borich-s-needs-assessment-model
#13
Sulaiman Umar, Norsida Man, Nolila Mohd Nawi, Ismail Abd Latif, Bahaman Abu Samah
The study described the perceived importance of, and proficiency in core agricultural extension competencies among extension workers in Peninsular Malaysia; and evaluating the resultant deficits in the competencies. The Borich's Needs Assessment Model was used to achieve the objectives of the study. A sample of 298 respondents was randomly selected and interviewed using a pre-tested structured questionnaire. Thirty-three core competency items were assessed. Instrument validity and reliability were ensured. The cross-sectional data obtained was analysed using SPSS for descriptive statistics including mean weighted discrepancy score (MWDS)...
February 6, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28188568/a-comprehensive-electronic-health-record-based-patient-navigation-module-including-technology-driven-colorectal-cancer-outreach-and-education
#14
Sunny Ajeesh, Rustveld Luis
The purpose of this concept paper is to propose an innovative multifaceted patient navigation module embedded in the Electronic Health Record (EHR) to address barriers to efficient and effective colorectal cancer (CRC) care. The EHR-based CRC patient navigation module will include several patient navigation features: (1) CRC screening registry; (2) patient navigation data, including CRC screening data, outcomes of patient navigation including navigation status (CRC screening referrals, fecal occult blood test (FOBT) completed, colonoscopy scheduled and completed, cancelations, reschedules, and no-shows); (3) CRC counseling aid; and 4) Web-based CRC education application including interactive features such as a standardized colonoscopy preparation guide, modifiable CRC risk factors, and links to existing resources...
February 10, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28188016/concurrent-chemoradiotherapy-vs-radiotherapy-alone-in-locally-advanced-cervix-cancer-a-systematic-review-and-meta-analysis
#15
REVIEW
Niloy Ranjan Datta, Emanuel Stutz, Michael Liu, Susanne Rogers, Dirk Klingbiel, Alexander Siebenhüner, Shalini Singh, Stephan Bodis
The efficacy of concurrent chemoradiotherapy (CTRT) in locally advanced cervix cancer (LACC, stages IIB-IVA) is contentious. This is due to the variable extent of therapeutic benefit reported in different randomized clinical trials and meta-analyses that usually include all stages of cervix cancer. A systematic review and meta-analysis was therefore conducted to evaluate the efficacy of concurrent CTRT over radiotherapy (RT) alone, predominantly in LACC for the key endpoints; complete response (CR), long-term loco-regional control (LRC), overall survival (OS), grade III/IV acute and late toxicities...
February 7, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28187709/the-drosophila-gene-expression-tool-dget-for-expression-analyses
#16
Yanhui Hu, Aram Comjean, Norbert Perrimon, Stephanie E Mohr
BACKGROUND: Next-generation sequencing technologies have greatly increased our ability to identify gene expression levels, including at specific developmental stages and in specific tissues. Gene expression data can help researchers understand the diverse functions of genes and gene networks, as well as help in the design of specific and efficient functional studies, such as by helping researchers choose the most appropriate tissue for a study of a group of genes, or conversely, by limiting a long list of gene candidates to the subset that are normally expressed at a given stage or in a given tissue...
February 10, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28187413/dato-an-atlas-of-biological-databases-and-tools
#17
Qilin Li, Yincong Zhou, Yingmin Jiao, Zhao Zhang, Lin Bai, Li Tong, Xiong Yang, Björn Sommer, Ralf Hofestädt, Ming Chen
This work presents DaTo, a semi-automatically generated world atlas of biological databases and tools. It extracts raw information from all PubMed articles which contain exact URLs in their abstract section, followed by a manual curation of the abstract and the URL accessibility. DaTo features a user-friendly query interface, providing extensible URL-related annotations, such as the status, the location and the country of the URL. A graphical interaction network browser has also been integrated into the DaTo web interface to facilitate exploration of the relationship between different tools and databases with respect to their ontology-based semantic similarity...
December 18, 2016: Journal of Integrative Bioinformatics
https://www.readbyqxmd.com/read/28187367/ontology-based-automatic-identification-of-public-health-related-turkish-tweets
#18
Emine Ela Küçük, Kürşad Yapar, Dilek Küçük, Doğan Küçük
Social media analysis, such as the analysis of tweets, is a promising research topic for tracking public health concerns including epidemics. In this paper, we present an ontology-based approach to automatically identify public health-related Turkish tweets. The system is based on a public health ontology that we have constructed through a semi-automated procedure. The ontology concepts are expanded through a linguistically motivated relaxation scheme as the last stage of ontology development, before being integrated into our system to increase its coverage...
February 4, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28187156/krilldb-a-de-novo-transcriptome-database-for-the-antarctic-krill-euphausia-superba
#19
Gabriele Sales, Bruce E Deagle, Enrica Calura, Paolo Martini, Alberto Biscontin, Cristiano De Pittà, So Kawaguchi, Chiara Romualdi, Bettina Meyer, Rodolfo Costa, Simon Jarman
Antarctic krill (Euphausia superba) is a key species in the Southern Ocean with an estimated biomass between 100 and 500 million tonnes. Changes in krill population viability would have catastrophic effect on the Antarctic ecosystem. One looming threat due to elevated levels of anthropogenic atmospheric carbon dioxide (CO2) is ocean acidification (lowering of sea water pH by CO2 dissolving into the oceans). The genetics of Antarctic krill has long been of scientific interest for both for the analysis of population structure and analysis of functional genetics...
2017: PloS One
https://www.readbyqxmd.com/read/28187096/a-call-for-new-communication-channels-for-gynecological-oncology-trainees-a-survey-on-social-media-use-and-educational-needs-by-the-european-network-of-young-gynecological-oncologists
#20
Kamil Zalewski, Kristina Lindemann, Michael J Halaska, Ignacio Zapardiel, Rene Laky, Elisabeth Chereau, David Lindquist, Stephan Polterauer, Vladislav Sukhin, Polat Dursun
OBJECTIVE: The aim of the study was to assess patterns in the use of social media (SM) platforms and to identify the training needs among European gynecologic oncology trainees. METHODS: In 2014, a web-based survey was sent to 633 trainees from the European Network of Young Gynaecological Oncologists (ENYGO) database. The 14-item questionnaire (partially using a 1- to 5-point Likert scale) assessed respondents' use of SM and preference for workshop content and organization...
March 2017: International Journal of Gynecological Cancer
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