keyword
https://read.qxmd.com/read/38630464/impact-of-oral-bisphosphonate-drug-holiday-on-mortality-following-hip-fracture-a-population-based-cohort-study
#1
JOURNAL ARTICLE
Miriam T Y Leung, Justin P Turner, Clara Marquina, Jenni Ilomaki, Tim Tran, J Simon Bell
CONTEXT: Current clinical guidelines recommend a drug holiday after extended use of oral bisphosphonates. However, no studies have investigated the impact of drug holidays before hip fractures on post-fracture mortality. OBJECTIVE: To investigate the effect of drug holiday on post-fracture mortality in patients with extended use of oral bisphosphonates. DESIGN: Retrospective population-based cohort study. SETTING: All patients with hip fractures in Victoria, Australia from 2014-18...
April 17, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38625579/development-and-internal-validation-of-a-multivariable-prediction-model-for-mortality-after-hip-fracture-with-machine-learning-techniques
#2
JOURNAL ARTICLE
Mathias Mosfeldt, Henrik Løvendahl Jørgensen, Jes Bruun Lauritzen, Karl-Åke Jansson
In order to estimate the likelihood of 1, 3, 6 and 12 month mortality in patients with hip fractures, we applied a variety of machine learning methods using readily available, preoperative data. We used prospectively collected data from a single university hospital in Copenhagen, Denmark for consecutive patients with hip fractures, aged 60 years and older, treated between September 2008 to September 2010 (n = 1186). Preoperative biochemical and anamnestic data were used as predictors and outcome was survival at 1, 3, 6 and 12 months after the fracture...
April 16, 2024: Calcified Tissue International
https://read.qxmd.com/read/38622754/safety-profile-of-hypnotics-or-sedatives-on-community-dwelling-older-adults-aged-75-or-older-in-japan-a-retrospective-propensity-matched-cohort-study
#3
JOURNAL ARTICLE
Nobuhiro Handa, Tatsuro Ishizaki, Seigo Mitsutake, Koki Ono, Masahiro Akishita
OBJECTIVE: The purpose of the study is to assess if daily use of hypnotics increases mortality, aspiration pneumonia and hip fracture among relatively healthy individuals aged 75 years or older who lead independent lives in the community. METHOD AND PATIENTS: Of the adults aged 75 years or older residing in Hokkaido prefecture of Japan (n = 705,538), those who did not meet several exclusion criteria were eligible for generating propensity score-matched cohorts (n = 214,723)...
April 2024: International Journal of Geriatric Psychiatry
https://read.qxmd.com/read/38622572/predictive-value-of-the-systemic-immune-inflammation-index-on-one-year-mortality-in-geriatric-hip-fractures
#4
JOURNAL ARTICLE
Zekeriya Ersin Çelen
BACKGROUND: Geriatric hip fractures are associated with a high incidence of mortality. This study examines the predictive value of the systemic immune-inflammation index (SII) on one-year mortality in elderly hip fracture patients. METHODS: A single-center retrospective study was conducted between February 2017 and October 2020. Three hundred and eleven surgically treated consecutive hip fracture patients were included in the study. Admission, postoperative first day, and postoperative fifth-day SII values were calculated...
April 15, 2024: BMC Geriatrics
https://read.qxmd.com/read/38613938/peripheral-perfusion-index-stratifies-risk-in-patients-with-intraoperative-anemia-a-multicentre-cohort-study
#5
JOURNAL ARTICLE
Frederik F Lau, Marianne Agerskov, Anna N W Thusholdt, Jakob Højlund, Christian S Meyhoff, Øivind Jans, Nicolai B Foss
STUDY OBJECTIVE: Evidence for red blood cell (RBC) transfusion thresholds in the intraoperative setting is limited, and current perioperative recommendations may not correspond with individual intraoperative physiological demands. Hemodynamics relevant for the decision to transfuse may include peripheral perfusion index (PPI). The objective of this prospective study was to assess the associations of PPI and hemoglobin levels with the risk of postoperative morbidity and mortality. DESIGN: Multicenter cohort study...
April 12, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38613102/malnutrition-related-health-outcomes-in-older-adults-with-hip-fractures-a-systematic-review-and-meta-analysis
#6
REVIEW
Manuela Chiavarini, Giorgia Maria Ricciotti, Anita Genga, Maria Ilaria Faggi, Alessia Rinaldi, Oriana Dunia Toscano, Marcello Mario D'Errico, Pamela Barbadoro
Hip fracture is a common condition in older adults, leading to disability and mortality. Several studies have demonstrated the association between nutritional status and the risk of a negative health outcome after fractures. In this systematic review, we evaluated the association between malnutrition and mortality, changes in mobility/living arrangements, and postoperative complications, such as delirium, in older patients with hip fractures. A literature search on the PubMed, Web of Science, and Scopus databases, up to September 2023, was conducted to identify all studies involving older subjects that reported an association between MNA/GNRI/PNI/CONUT and health outcome after hip fracture...
April 5, 2024: Nutrients
https://read.qxmd.com/read/38610777/the-impact-of-implementation-of-palliative-non-operative-management-on-mortality-of-operatively-treated-geriatric-hip-fracture-patients-a-retrospective-cohort-study
#7
JOURNAL ARTICLE
Thomas Nijdam, Tim Schiepers, Duco Laane, Henk Jan Schuijt, Detlef van der Velde, Diederik Smeeing
(1) Background: Hip fracture patients with very limited life expectancy can opt for non-operative management (NOM) within a palliative care context. The implementation of NOM in the palliative context may affect the mortality of the operatively treated population. This retrospective cohort study aimed to determine whether the operatively treated geriatric hip fracture population would have a lower in-hospital mortality rate and fewer postoperative complications after the introduction of NOM within a palliative care context for patients with very limited life expectancy...
March 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610614/evaluation-of-outcome-after-total-hip-arthroplasty-for-femoral-neck-fracture-which-factors-are-relevant-for-better-results
#8
JOURNAL ARTICLE
Paolo Schiavi, Francesco Pogliacomi, Matteo Bergamaschi, Francesco Ceccarelli, Enrico Vaienti
Background: Femoral neck fractures (FNFs) are frequent orthopedic injuries in elderly patients. Despite improvements in clinical monitoring and advances in surgical procedures, 1-year mortality remains between 15% and 30%. The aim of this study is to identify variables that lead to better outcomes in patients treated with total hip arthroplasty (THA) for FNFs. Methods: All patients who underwent cementless THA for FNF from January 2018 to December 2022 were identified. Patients aged more than 80 years old and with other post-traumatic lesions were excluded...
March 23, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38608626/neoplastic-pathologic-hip-fractures-are-associated-with-a-higher-risk-of-post-operative-bleeding-and-thromboembolic-events
#9
JOURNAL ARTICLE
Marcos R Gonzalez, Daniel Karczewski, Angad Ds Bedi, Hayley Denwood, Santiago A Lozano-Calderon
INTRODUCTION: Surgical treatment of hip fractures leads to significant post-operative complications. Although pathologic fractures (PF) are associated with worse outcomes, most studies do not differentiate between etiology (neoplastic and non-neoplastic PF). We seek to compare 30-day complication rates between 1) native hip fractures and neoplastic PF, and 2) neoplastic and non-neoplastic PF. MATERIALS AND METHODS: A total of 127,819 patients with hip fractures and 5104 with PF diagnosed from 2005 to 2021 were retrieved from the NSQIP database...
April 9, 2024: Surgical Oncology
https://read.qxmd.com/read/38604278/discharge-to-a-skilled-nursing-facility-after-hip-fracture-results-in-higher-rates-of-periprosthetic-joint-infection
#10
JOURNAL ARTICLE
Emily A Treu, Jeffrey J Frandsen, Graham J DeKeyser, Brenna E Blackburn, Michael J Archibeck, Lucas A Anderson, Jeremy M Gililland
INTRODUCTION: Femoral neck fractures (FNF) in elderly patients are associated with major morbidity and mortality. The influence of postoperative discharge location on recovery and outcomes after arthroplasty for hip fractures is not well understood. METHODS: A multi-site retrospective cohort from nine academic centers identified patients who had FNF treated with hemiarthroplasty (HA) or total hip arthroplasty (THA) between 2010 and 2019. Patients who had diagnoses of dementia, stroke, age > 80 years, or high energy fracture were excluded...
April 9, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38600249/the-association-between-prealbumin-concentration-at-admission-and-mortality-in-elderly-patients-with-hip-fractures-a-cohort-study
#11
JOURNAL ARTICLE
Shao-Hua Chen, Bin-Fei Zhang, Yu-Min Zhang
UNLABELLED: Malnutrition is associated with complications and mortality in patients of hip fracture. Prealbumin may be more suitable than albumin to accurately predict the prognosis of hip fracture in elderly patients. We found that prealbumin concentration was nonlinearly associated with mortality in elderly patients with hip fracture, and an inflection point effect was observed. OBJECTIVE: To evaluate the association between prealbumin concentration at admission and mortality in elderly patients with hip fractures...
April 11, 2024: Archives of Osteoporosis
https://read.qxmd.com/read/38596507/postfracture-survival-in-a-population-based-study-of-adults-aged%C3%A2-%C3%A2-66%C3%A2-yr-a-call-to-action-at-hospital-discharge
#12
JOURNAL ARTICLE
Geneviève Vincent, Jonathan D Adachi, Emil Schemitsch, Jean-Eric Tarride, Nathan Ho, Rajvi J Wani, Jacques P Brown
Postfracture survival rates provide prognostic information but are rarely reported along with other mortality outcomes in adults aged ≥50 yr. The timing of survival change following a fracture also needs to be further elucidated. This population-based, matched-cohort, retrospective database study examined 98 474 patients (73% women) aged ≥66 yr with an index fracture occurring at an osteoporotic site (hip, clinical vertebral, proximal non-hip non-vertebral [pNHNV], and distal non-hip non-vertebral [dNHNV]) from 2011 to 2015, who were matched (1:1) to nonfracture individuals based on sex, age, and comorbidities...
May 2024: JBMR Plus
https://read.qxmd.com/read/38596506/it-is-not-just-a-fracture
#13
EDITORIAL
Peggy M Cawthon, Matthew Drake
In their recent population-based study of nearly 100 000 patients from Ontario, Canada, who had suffered a fracture, Vincent et al. characterized postfracture survival rates. Their findings showed that overall survival was decreased particularly following fractures of the hip or vertebrae, and was worse in men and the oldest old. They found that relative survival, particularly after hip fracture, is strikingly poor with less than one-third of men and one-half of women surviving for 5 years following hip fracture, survival which was far less than that seen for patients afflicted by both prostate and breast cancers...
May 2024: JBMR Plus
https://read.qxmd.com/read/38595218/outcomes-of-patients-with-preoperative-thrombocytosis-after-hip-fracture-surgery
#14
JOURNAL ARTICLE
Christian A Gonzalez, Noelle L Van Rysselberghe, Clayton Maschhoff, Michael J Gardner
INTRODUCTION: Low platelet counts have clinically relevant effects on patient outcomes after hip fracture surgery; however, the relationship between abnormally high platelet counts and postoperative outcomes in this population is unknown. METHODS: The ACS-NSQIP database was queried for patients who underwent hip fracture surgery between 2015 and 2019. Outcomes were compared between patients with normal platelet counts (150,000 to 450,000/μL) and thrombocytosis (>450,000/μL)...
April 1, 2024: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/38592463/a-retrospective-chart-analysis-with-5-year-follow-up-of-early-care-for-geriatric-hip-fracture-patients-why-we-should-continue-talking-about-hip-fractures
#15
JOURNAL ARTICLE
An Sermon, Evelyne Verhulst, Laurens Aerden, Harm Hoekstra
BACKGROUND: Timing of surgery remains a topic of debate for hip fracture treatment in the geriatric patient population. The quality indicator "early surgery" was implemented in 2014 at the Department of Trauma Surgery of the University Hospitals Leuven to enhance timely operative treatment. In this follow-up study, we aim to evaluate the performance of this quality indicator, the clinical outcomes, and room for improvement. METHODS: The charts of 1190 patients surgically treated for an acute hip fracture were reviewed between June 2017 and May 2022 at the University Hospitals Leuven...
April 9, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38590487/intraoperative-use-of-high-flow-nasal-cannula-in-elderly-patients-undergoing-hip-fracture-repair-under-spinal-anesthesia-a-randomized-controlled-study
#16
JOURNAL ARTICLE
Majid F Mutar, Habiba Ben Hamada, Talib Razaq M Askar, Lassaad Hassini, Walid Naija, Mohamed Kahloul
BACKGROUND: The procedure of hip fracture repair poses a risk for postoperative pulmonary complications (PPCs) in elderly patients, accompanied by anesthesia and operations. Various noninvasive methods of respiratory support are used as prophylactic and therapeutic, mainly in the postoperative period.  Objective: This study aims to determine whether intraoperative use of a high-flow nasal cannula (HFNC) impacts elderly patient outcomes after hip fracture surgery. METHOD: Seventy patients aged 65 and older undergoing traumatic hip surgery under spinal anesthesia for isolated hip fractures were randomly assigned to either an interventional group (I) utilizing a high-flow nasal cannula or a control group (C) without respiratory intervention in a six-month single-blind controlled study at Sahloul Teaching Hospital...
March 2024: Curēus
https://read.qxmd.com/read/38589787/does-post-acute-care-reduce-the-mortality-of-octogenarian-and-nonagenarian-patients-undergoing-hip-fracture-surgery
#17
JOURNAL ARTICLE
Yu-Wei Chiang, Yu-Jun Chang, Hui-Jen Huang, Cheng-Pu Hsieh, Yueh-Hsiu Lu
BACKGROUND: With the increasing number of elderly individuals worldwide, a greater number of people aged 80 years and older sustain fragility fracture due to osteopenia and osteoporosis. METHODS: This retrospective study included 158 older adults, with a median age of 85 (range: 80-99) years, who sustained hip fragility fracture and who underwent surgery. The patients were divided into two groups, one including patients who joined the post-acute care (PAC) program after surgery and another comprising patients who did not...
April 8, 2024: BMC Geriatrics
https://read.qxmd.com/read/38587621/dysphagia-is-associated-with-increased-mortality-risk-after-hip-fracture-surgery
#18
JOURNAL ARTICLE
Rohan M Boyapati, Timothy M Hoggard, Seth R Yarboro, Michael M Hadeed
PURPOSE: This study aims to explore the prevalence of dysphagia, as well as mortality associated with dysphagia in the elderly population receiving surgical treatment for a hip fracture. METHODS: A retrospective cohort study was completed at an academic level 1 tertiary care center. Patients older than or equal to 65 admitted with a hip fracture diagnosis from January 2015 to December 2020 (n = 617) were included. The main outcome was the prevalence of dysphagia and association with mortality...
April 8, 2024: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://read.qxmd.com/read/38582221/the-use-of-uncemented-stems-in-femoral-neck-fractures-in-elderly-patients-a-comparative-study-of-671-cases
#19
JOURNAL ARTICLE
Alexandre Gounot, Anahita Charlot, Pascal Guillon, Augustin Schaefer, Aymane Moslemi, Pierre Boutroux, Alain Sautet
INTRODUCTION: The use of cemented stems in elderly patients is associated with the risk of intraoperative embolic complications. Uncemented stems eliminate this risk, but their use is controversial because of the risk of mechanical complications, with estimated subsidence between 3.6% and 30% and periprosthetic fractures between 2.1% and 11% at 6 weeks. A retrospective multicenter comparative study was conducted using a propensity score analysis to evaluate mechanical performances of uncemented stems in femoral neck fractures in elderly patients to 1) compare the risk of mechanical complications and 2) assess the use of metaphyseal-anchored stems for this indication...
April 4, 2024: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://read.qxmd.com/read/38580737/enhancing-fracture-diagnosis-in-pelvic-x-rays-by-deep-convolutional-neural-network-with-synthesized-images-from-3d-ct
#20
JOURNAL ARTICLE
Rashedur Rahman, Naomi Yagi, Keigo Hayashi, Akihiro Maruo, Hirotsugu Muratsu, Syoji Kobashi
Pelvic fractures pose significant challenges in medical diagnosis due to the complex structure of the pelvic bones. Timely diagnosis of pelvic fractures is critical to reduce complications and mortality rates. While computed tomography (CT) is highly accurate in detecting pelvic fractures, the initial diagnostic procedure usually involves pelvic X-rays (PXR). In recent years, many deep learning-based methods have been developed utilizing ImageNet-based transfer learning for diagnosing hip and pelvic fractures...
April 5, 2024: Scientific Reports
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