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https://www.readbyqxmd.com/read/30120760/the-effects-of-nocturnal-blood-pressure-paterns-and-autonomic-alterations-on-erectile-functions-in-patients-with-hypertension
#1
Ercan Yuvanc, Mehmet Tolga Dogru, Vedat Simsek, Hüseyin Kandemir, Devrim Tuglu
PURPOSE: Hypertension (HT) is known to be of the main risk factors for erectile dysfunction (ED). But non-dipping (<%10 drop in the night) of HT is not investigated truly. The aim of this study was to test the hypothesis that the non-dipper hypertensive patients are more prone to develop erectile dysfunction. MATERIALS AND METHODS: This was a cross-sectional clinical study. 70 HT patients diagnosed by Ambulatory blood pressure monitoring (ABPM) were classified into 3 groups (No ED, mild to moderate and severe) according to their International Index of Erectile Function (IIEF) scores...
August 18, 2018: Urology Journal
https://www.readbyqxmd.com/read/30093314/morning-blood-pressure-surge-relates-to-autonomic-neural-activity-in-young-non-dipping-adults-the-african-predict-study
#2
Gontse G Mokwatsi, Aletta E Schutte, Catharina M C Mels, Ruan Kruger
BACKGROUND: It is well established that an exaggerated morning blood pressure surge (MBPS) is associated with an increased risk for cardiovascular disease development in hypertensive individuals. However, in non-dipping individuals, a lower surge was reportedly associated with increased cardiovascular risk. Sympathetic nervous system activity is involved in 24-hour blood pressure fluctuations, including night-time dipping and the MBPS. To better understand this interaction, we investigated associations of MBPS with heart-rate variability and baroreceptor sensitivity in young healthy dippers and non-dippers...
July 30, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/30087063/is-there-an-association-between-non-dipping-blood-pressure-and-measures-of-glucose-variability-in-type-1-diabetes
#3
Mamta Jaiswal, Lynn Ang, Kara Mizokami-Stout, Rodica Pop-Busui
AIM: To assess the relationship between glucose variability (GV) and non-dipping of blood pressure (BP) as a marker of cardiovascular autonomic neuropathy (CAN) among patients with type 1 diabetes (T1D). METHODS: Forty-one subjects with T1D (age 34 ± 13 years, duration 13 ± 6 years, HbA1c 8 ± 1.2%) without cardiovascular disease, dyslipidemia, or hypertension at baseline were enrolled in a 3-year observational cohort study. Subjects were phenotyped for CAN with heart rate variability, cardiovascular autonomic reflex tests, and 24-h BP profiles at baseline and during follow-up...
October 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/30076842/performance-indicators-in-colonoscopy-after-certification-for-independent-practice-outcomes-and-predictors-of-competence
#4
Keith Siau, James Hodson, Roland M Valori, Stephen T Ward, Paul Dunckley
BACKGROUND: Robust real-world performance data of newly independent colonoscopists are lacking. In the United Kingdom, provisional colonoscopy certification (PCC) marks the transition from training to newly independent practice. We aimed to assess changes in key performance indicators (KPIs) such as cecal intubation rate (CIR) in the periods pre- and post-PCC, particularly regarding rates and predictors of trainees exhibiting a drop-in performance (DIP), defined as CIR <90% in the first 50 procedures post-PCC...
August 1, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/30038337/morning-blood-pressure-surge-in-young-black-and-white-adults-the-african-predict-study
#5
Gontse Gratitude Mokwatsi, Aletta Elisabeth Schutte, Catharina Martha Cornelia Mels, Ruan Kruger
An exaggerated morning blood pressure surge (MBPS) has independent predictive value for cardiovascular mortality and is suggested to be prevalent in elderly hypertensive patients: men and white populations. To better understand the MBPS profile in a young and normotensive population, we evaluated the MBPS in young adults and explored associations with demographic, cardiovascular and health behaviour measurements. We included 845 black (n = 439) and white (n = 406) men and women aged between 20 and 30 years...
July 23, 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/30003696/patterns-of-ambulatory-blood-pressure-clinical-relevance-and-application
#6
Eoin O'Brien, Kazuomi Kario, Jan A Staessen, Alejandro de la Sierra, Takayoshi Ohkubo
Ambulatory blood pressure measurement (ABPM) is now recommended in all patients suspected of having hypertension. However, in practice, the mean daytime pressures are often used to make diagnostic and therapeutic decisions, and the information from abnormal patterns of blood pressure behavior is often overlooked. This paper presents daytime patterns (eg, white coat hypertension and siesta dipping), nocturnal patterns (eg, dipping, non-dipping, reverse dipping, and the morning surge), and discusses ambulatory hypotension, and abnormal patterns and indices of related hemodynamic parameters (eg, heart rate, pulse pressure, and blood pressure variability)...
July 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29973135/genome-wide-association-study-of-nocturnal-blood-pressure-dipping-in-hypertensive-patients
#7
Jenni M Rimpelä, Ilkka H Pörsti, Antti Jula, Terho Lehtimäki, Teemu J Niiranen, Lasse Oikarinen, Kimmo Porthan, Antti Tikkakoski, Juha Virolainen, Kimmo K Kontula, Timo P Hiltunen
BACKGROUND: Reduced nocturnal fall (non-dipping) of blood pressure (BP) is a predictor of cardiovascular target organ damage. No genome-wide association studies (GWAS) on BP dipping have been previously reported. METHODS: To study genetic variation affecting BP dipping, we conducted a GWAS in Genetics of Drug Responsiveness in Essential Hypertension (GENRES) cohort (n = 204) using the mean night-to-day BP ratio from up to four ambulatory BP recordings conducted on placebo...
July 4, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29875006/ambulatory-blood-pressure-monitoring-in-type-2-diabetes-mellitus-a-cross-sectional-study
#8
Florence Gunawan, Hui Yi Ng, Christopher Gilfillan, Mahesan Anpalahan
BACKGROUND: Ambulatory blood pressure (ABP) monitoring in type 2 diabetes (T2DM) is not yet routine in clinical practice. OBJECTIVES: To quantify abnormal ABP patterns and their associations with diabetic complications, and to assess the reliability of office blood pressure (OBP) for assessing BP in T2DM. METHODS: In a cross-sectional study, eligible patients with T2DM underwent OBP and 24- hour ABP measurements under standardized conditions and screening for diabetic complications...
June 6, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29845738/relationship-between-nocturnal-polyuria-and-non-dipping-blood-pressure-in-male-patients-with-lower-urinary-tract-symptoms
#9
Misato Takayama, So Omori, Kazuhiro Iwasaki, Ei Shiomi, Ryo Takata, Jun Sugimura, Takaya Abe, Wataru Obara
OBJECTIVE: The aim of the present study was to examine factors of nocturnal polyuria and blood pressure variability in male patients with lower urinary tract symptoms (LUTS) who were treated. METHODS: Two hundred and forty-two male patients with LUTS who were treated recorded frequency volume charts. We investigated their urinary condition and characteristics, medical history, and medications. Thirty-four of these patients underwent ambulatory blood pressure monitoring (ABPM) for 24 hours to evaluate blood pressure variability...
May 29, 2018: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/29766366/consensus-statement-on-the-definition-of-neurogenic-supine-hypertension-in-cardiovascular-autonomic-failure-by-the-american-autonomic-society-aas-and-the-european-federation-of-autonomic-societies-efas-endorsed-by-the-european-academy-of-neurology-ean-and-the
#10
REVIEW
Alessandra Fanciulli, Jens Jordan, Italo Biaggioni, Giovanna Calandra-Buonaura, William P Cheshire, Pietro Cortelli, Sabine Eschlboeck, Guido Grassi, Max J Hilz, Horacio Kaufmann, Heinz Lahrmann, Giuseppe Mancia, Gert Mayer, Lucy Norcliffe-Kaufmann, Anne Pavy-Le Traon, Satish R Raj, David Robertson, Isabel Rocha, Walter Struhal, Roland Thijs, Konstantinos P Tsioufis, J Gert van Dijk, Gregor K Wenning
PURPOSE: Patients suffering from cardiovascular autonomic failure often develop neurogenic supine hypertension (nSH), i.e., high blood pressure (BP) in the supine position, which falls in the upright position owing to impaired autonomic regulation. A committee was formed to reach consensus among experts on the definition and diagnosis of nSH in the context of cardiovascular autonomic failure. METHODS: As a first and preparatory step, a systematic search of PubMed-indexed literature on nSH up to January 2017 was performed...
May 15, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29736422/cerebral-microbleeds-and-blood-pressure-abnormalities-in-parkinson-s-disease
#11
Kazuo Yamashiro, Ryota Tanaka, Yasushi Shimo, Genko Oyama, Takashi Ogawa, Atsushi Umemura, Nobutaka Hattori
Blood pressure abnormalities are frequently observed in patients with Parkinson's disease (PD), and are associated with cerebrovascular diseases such as white matter hyperintensities and carotid atherosclerosis. We assessed the relationship between blood pressure abnormalities and cerebral microbleeds (CMBs), a marker of cerebral small vessel disease, in 128 patients with PD. We examined supine and orthostatic blood pressures and used 24-hour ambulatory blood pressure monitoring to assess the presence or absence of orthostatic hypotension (OH), supine hypertension (SH), nocturnal hypertension (NH), and loss of nocturnal blood pressure dips (non-dipping)...
March 2018: ENeurologicalSci
https://www.readbyqxmd.com/read/29733344/impact-of-blunted-nocturnal-blood-pressure-dipping-on-cardiac-systolic-function-in-community-participants-not-receiving-antihypertensive-therapy
#12
Angela J Woodiwiss, Carlos D Libhaber, Pinhas Sareli, Gavin R Norton
BACKGROUND: Blunted nocturnal blood pressure (BP) dipping (nondipping) predicts cardiovascular morbidity and mortality, and is associated with heart failure (HF) independent of office BP. Whether nondipping is independently associated with cardiac systolic function prior to the development of HF is uncertain. METHODS: We assessed whether nocturnal BP dipping pattern and nocturnal BP were associated with indexes of cardiac systolic function [endocardial fractional shortening (endFS), midwall FS (mFS), ejection fraction (EF)] independent of left ventricular mass index (LVMI) and relative wall thickness (RWT) in 491 randomly selected community participants not receiving antihypertensive therapy...
August 3, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29678625/ambulatory-blood-pressure-monitoring-profiles-in-a-cross-sectional-analysis-of-a-large-database-of-normotensive-and-true-or-suspected-hypertensive-patients
#13
Sara Araújo, Ana Rouxinol-Dias, José Mesquita-Bastos, José Silva, Loide Barbosa, Jorge Polónia
OBJECTIVE: To assess ambulatory blood pressure monitoring (ABPM) circadian patterns and their determinants in a large sample of normotensive and hypertensive patients. METHODS: A total of 26170 individual ABPM recordings from 1995 to 2015 were analyzed. Mean office blood pressure (OBP), 24-hour blood pressure (BP), daytime BP and nocturnal BP were measured. Circadian patterns were classified by nocturnal systolic BP fall as extreme dipper (ED, ≥20%), dipper (D, 10%-19...
April 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29576408/insomnia-and-hypertension-a-systematic-review
#14
REVIEW
Denise C Jarrin, Pasquale K Alvaro, Marc-André Bouchard, Stephanie D Jarrin, Christopher L Drake, Charles M Morin
Insomnia is a prevalent sleep disorder that is associated with a multitude of health consequences. Particularly, insomnia has been associated with cardiovascular disease and its precursors, such as hypertension and blood pressure (BP) non-dipping. The present systematic review aimed to summarize the evidence on the concurrent and prospective associations between insomnia and hypertension and/or BP. Using electronic search engines (PubMed, SCOPUS, PsycINFO), 5,618 articles published from January 1970 to December 2017 were identified, and 64 met the inclusion criteria (26 to 162,121 participants; age range: 18-100; 46...
October 2018: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29537687/neurocardiovascular-pathology-in-pre-manifest-and-early-stage-huntington-s-disease
#15
E Bellosta Diago, J Pérez-Pérez, S Santos Lasaosa, A Viloria Alebesque, S Martínez-Horta, J Kulisevsky, J López Del Val
BACKGROUND AND PURPOSE: Cardiovascular events are a major cause of early death in the Huntington's disease (HD) population. Dysautonomia as well as deterioration of circadian rhythms can be detected early in the disease progression and can have profound effects on cardiac health. The aim of the present study was to determine if patients with HD and pre-manifest mutation carriers present a higher risk of cardiovascular disease than non-mutation-carrying controls. METHODS: This was a prospective, cross-sectional, multicentre study of 38 HD mutation carriers (23 pre-manifest and 15 early-stage patients) compared with 38 age- and gender-matched healthy controls...
July 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29531290/risk-of-incident-chronic-kidney-disease-is-better-reduced-by-bedtime-than-upon-awakening-ingestion-of-hypertension-medications
#16
Ramón C Hermida, Diana E Ayala, Artemio Mojón, José R Fernández
This trial investigated whether therapy with the entire daily dose of ≥1 hypertension medications at bedtime exerts a greater reduction in the risk of incident chronic kidney disease (CKD) than therapy with all medications upon awakening. We conducted a prospective, open-label, blinded endpoint trial of 2078 hypertensive patients without CKD (1017 men/1061 women, 53.6 ± 13.7 years of age) randomized to ingest all their prescribed hypertension medications upon awakening (n = 1041) or the entire daily dose of ≥1 of those medications at bedtime (n = 1037)...
May 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29528363/west-african-ancestry-and-nocturnal-blood-pressure-in-african-americans-the-jackson-heart-study
#17
John N Booth, Man Li, Daichi Shimbo, Rachel Hess, Marguerite R Irvin, Rick Kittles, James G Wilson, Lynn B Jorde, Alfred K Cheung, Leslie A Lange, Ethan M Lange, Yuichiro Yano, Paul Muntner, Adam P Bress
BACKGROUND: African Americans have a higher prevalence of nocturnal hypertension and nondipping blood pressure than European Americans, but the genetic contribution to these racial differences remains unclear. We assessed the association of the percentage West African genetic ancestry with nocturnal hypertension and nondipping blood pressure in 932 African Americans from the Jackson Heart Study. METHODS: Using percentage West African ancestry determined from 389 ancestry informative markers, participants were categorized into tertiles (tertile 1 [low]: <79...
May 7, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29523837/association-of-nocturnal-blood-pressure-patterns-with-inflammation-and-central-and-peripheral-estimates-of-vascular-health-in-rheumatoid-arthritis
#18
Eugenia Gkaliagkousi, Panagiota Anyfanti, Sophia Chatzimichailidou, Areti Triantafyllou, Antonios Lazaridis, Spyros Aslanidis, Stella Douma
Predictors of adverse cardiovascular outcomes include elevated nighttime systolic blood pressure (SBP) and a non-dipping pattern. We investigated whether these factors correlate with systemic inflammation, cardiovascular risk, and markers of central and peripheral vascular damage in rheumatoid arthritis (RA), a disease characterized by excess cardiovascular risk. Twenty-four-hour ambulatory blood pressure monitoring was applied in patients and controls. Vascular assessments included measurement of arterial stiffness (pulse wave velocity) and carotid atherosclerosis (carotid intima-media thickness)...
April 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29488402/the-association-between-circulating-endostatin-and-a-disturbed-circadian-blood-pressure-pattern-in-patients-with-type-2-diabetes
#19
Jonas Wuopio, Carl Johan Östgren, Toste Länne, Lars Lind, Toralph Ruge, Axel C Carlsson, Anders Larsson, Fredrik H Nyström, Johan Ärnlöv
BACKGROUND: Endostatin, cleaved from collagen XVIII in the extracellular matrix, is a promising circulating biomarker for cardiovascular damage. It possesses anti-angiogenic and anti-fibrotic functions and has even been suggested to be involved in blood pressure regulation. Less is known if endostatin levels relate to circadian blood pressure patterns. In the present paper we studied the association between circulating levels of endostatin and nocturnal dipping in blood pressure. METHODS: We used the CARDIPP-study, a cohort of middle aged, type 2 diabetics (n = 593, 32% women), with data on both 24-hour and office blood pressure, serum-endostatin, cardiovascular risk factors, and incident major cardiovascular events...
August 2018: Blood Pressure
https://www.readbyqxmd.com/read/29435868/ambulatory-blood-pressure-profiles-in-familial-dysautonomia
#20
Lior Goldberg, Bat-El Bar-Aluma, Alex Krauthammer, Ori Efrati, Yehonatan Sharabi
OBJECTIVE: Familial dysautonomia (FD) is a rare genetic disease that involves extreme blood pressure fluctuations secondary to afferent baroreflex failure. The diurnal blood pressure profile, including the average, variability, and day-night difference, may have implications for long-term end organ damage. The purpose of this study was to describe the circadian pattern of blood pressure in the FD population and relationships with renal and pulmonary function, use of medications, and overall disability...
August 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
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