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https://www.readbyqxmd.com/read/29226654/evaluation-of-hepcidin-and-atherosclerosis-in-dialysis-patients
#1
Victor Manolov, Julia Petrova, Boris Bogov, Savina Hadjidekova, Vasil Vasilev, Dyana Yonova, Maria Petrova, Todor Kunchev, Yavor Jelev, Petar Jeliazkov, Borislav Marinov, Ivo Bogov, Zlatina Gramatikova, Silviya Voleva, Kamen Tzatchev, Latchezar Traykov
BACKGROUND: Chronic kidney disease (CKD) is a condition that involves 10% - 15% of population worldwide, which increases the risk of cardio-vascular diseases (CVD). Chronic kidney disease is one of the main reasons for illness and mortality in the world. Chronic kidney disease is a serious health problem caused by involvement of a large number of patients with kidney injury, especially in industrial countries. Among the main reasons for this are population living longer and the number of diseases in elderly persons, such as diabetes mellitus type 2, hypertension, and cardio-vascular diseases...
November 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29220680/adherence-to-physical-activity-recommendations-and-physical-and-mental-health-risk-in-people-with-severe-mental-illness-in-uganda
#2
Davy Vancampfort, Michel Probst, David Basangwa, Marc De Hert, Inez Myin-Germeys, Ruud van Winkel, Philip B Ward, Simon Rosenbaum, James Mugisha
This study investigated cardio-metabolic risk factors among patients with severe mental illness who do or do not meet the recommendations of 150min per week of physical activity. A secondary aim was to assess whether those that do meet the recommendations report lower levels of mental health symptoms. 107 (60♀) Ugandan in- and outpatients (mean age=34.4 ± 9.7 years) with severe mental illness (depression=7, bipolar disorder=55, schizophrenia=45) completed the Physical Activity Vital Sign (PAVS) method and Brief Symptoms Inventory -18...
November 29, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29219101/health-effects-of-milder-winters-a-review-of-evidence-from-the-united-kingdom
#3
REVIEW
Shakoor Hajat
Cold-related mortality and morbidity remains an important public health problem in the UK and elsewhere. Health burdens have often reported to be higher in the UK compared to other countries with colder climates, however such assessments are usually based on comparison of excess winter mortality indices, which are subject to biases. Daily time-series regression or case-crossover studies provide the best evidence of the acute effects of cold exposure. Such studies report a 6% increase in all-cause deaths in England & Wales for every 1 °C fall in daily mean temperature within the top 5% of the coldest days...
December 5, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29216229/factors-associated-with-pre-diabetes-in-tehranian-men-and-women-a-structural-equations-modeling
#4
Parisa Amiri, Sara Jalali-Farahani, Mehrdad Karimi, Reza Taherian, Sara Kazempour-Ardebili, Firoozeh Hosseini-Esfahani, Parvin Mirmiran, Fereidoun Azizi
OBJECTIVE: To examine associations of sex-specific related factors with pre-diabetes in Tehranian non-diabetic adults. METHODS: This study has been conducted within the framework of the Tehran Lipid and Glucose Study (TLGS) between 2008-2010. A total of 5568 (55.4% female) non-diabetic adults, aged ≥20 years, selected from among participants of the TLGS, were recruited for the study. Data on socio-behavioral factors, family history of diabetes and cardio-metabolic risk factors were included in the hypothesized model to test their direct and indirect associations with pre-diabetes in men and women separately, using structural equation modeling...
2017: PloS One
https://www.readbyqxmd.com/read/29212477/nurse-health-and-lifestyle-modification-versus-standard-care-in-40-to-70-year-old-regional-adults-study-protocol-of-the-management-to-optimise-diabetes-and-metabolic-syndrome-risk-reduction-via-nurse-led-intervention-modern-randomized-controlled-trial
#5
Melinda J Carrington, Paul Zimmet
BACKGROUND: Metabolic syndrome (MetS), the clustering of multiple leading risk factors, predisposes individuals to increased risk for developing type 2 diabetes and/or cardiovascular disease (CVD). Cardio-metabolic disease risk increases with greater remoteness where specialist services are scarce. Nurse-led interventions are effective for the management of chronic disease. The aim of this clinical trial is to determine whether a nurse-implemented health and lifestyle modification program is more beneficial than standard care to reduce cardio-metabolic abnormalities and future risk of CVD and diabetes in individuals with MetS...
December 6, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29211804/the-cardio-metabolic-impact-of-taking-commonly-prescribed-analgesic-drugs-in-133-401-uk-biobank-participants
#6
Sophie Cassidy, Michael I Trenell, Kirstie N Anderson
OBJECTIVE: There has been a significant increase in the prescribing of medication for chronic non-cancer pain. In a UK population sample, we aimed to assess cardio-metabolic (CM) health in those taking these chronic pain medications. METHODS: 133,401 participants from the UK Biobank cohort were studied. BMI, waist cm and hypertension were compared between those on drugs prescribed for chronic pain and CM drugs to those on CM drugs only. Multiple confounders were controlled for...
2017: PloS One
https://www.readbyqxmd.com/read/29206204/antioxidants-protect-against-arsenic-induced-mitochondrial-cardio-toxicity
#7
REVIEW
Clare Pace, Ruben Dagda, Jeff Angermann
Arsenic is a potent cardiovascular toxicant associated with numerous biomarkers of cardiovascular diseases in exposed human populations. Arsenic is also a carcinogen, yet arsenic trioxide is used as a therapeutic agent in the treatment of acute promyelotic leukemia (APL). The therapeutic use of arsenic is limited due to its severe cardiovascular side effects. Many of the toxic effects of arsenic are mediated by mitochondrial dysfunction and related to arsenic's effect on oxidative stress. Therefore, we investigated the effectiveness of antioxidants against arsenic induced cardiovascular dysfunction...
December 5, 2017: Toxics
https://www.readbyqxmd.com/read/29204319/reference-standards-to-assess-physical-fitness-of-children-and-adolescents-of-brazil-an-approach-to-the-students-of-the-lake-itaip%C3%A3%C2%BA-region-brazil
#8
Edilson Hobold, Vitor Pires-Lopes, Rossana Gómez-Campos, Miguel de Arruda, Cynthia Lee Andruske, Jaime Pacheco-Carrillo, Marco Antonio Cossio-Bolaños
Background: The importance of assessing body fat variables and physical fitness tests plays an important role in monitoring the level of activity and physical fitness of the general population. The objective of this study was to develop reference norms to evaluate the physical fitness aptitudes of children and adolescents based on age and sex from the lake region of Itaipú, Brazil. Methods: A descriptive cross-sectional study was carried out with 5,962 students (2,938 males and 3,024 females) with an age range of 6...
2017: PeerJ
https://www.readbyqxmd.com/read/29197155/high-intensity-interval-training-improves-insulin-sensitivity-in-older-individuals
#9
D Søgaard, M T Lund, C M Scheuer, M S Dehlbaek, S G Dideriksen, C V Abildskov, K K Christensen, T L Dohlmann, S Larsen, A H Vigelsø, F Dela, J W Helge
AIM: Metabolic health may deteriorate with age as a result of altered body composition and decreased physical activity. Endurance exercise is known to counter these changes delaying or even preventing onset of metabolic diseases. High-intensity interval training (HIIT) is a time efficient alternative to regular endurance exercise and the aim of this study is to investigate the metabolic benefit of HIIT in older subjects. METHODS: 22 sedentary male (n=11) and female (n=11) subjects aged 63 ± 1 years performed HIIT training three times/week for six weeks on a bicycle ergometer...
December 2, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/29195897/an-inflammatory-environment-containing-tnf%C3%AE-favors-tet2-mutant-clonal-hematopoiesis
#10
Samuel O Abegunde, Rena Buckstein, Richard A Wells, Michael J Rauh
Clonal hematopoiesis of aging and indeterminate potential (ARCH or CHIP), driven mainly by mutations in DNMT3A and TET2, is an emerging public health issue, affecting at least 10-15% of adults older than 65 years. CHIP is associated with increased risks of de novo and therapy-related hematological neoplasms and serves as a reservoir for leukemic relapse. CHIP is also associated with increased all-cause mortality and risk of cardio-metabolic disease. The latter association may be explained, at least in part, by the effects of inactivating mutations in TET2 on progeny macrophages...
November 28, 2017: Experimental Hematology
https://www.readbyqxmd.com/read/29191247/the-implication-of-the-shortage-of-health-workforce-specialist-on-universal-health-coverage-in-kenya
#11
Mumbo Hazel Miseda, Samuel Odhiambo Were, Cirindi Anne Murianki, Milo Peter Mutuku, Stephen N Mutwiwa
BACKGROUND: Globally, there is an acute shortage of human resources for health (HRH), and the greatest burden is borne by low-income countries especially in sub-Saharan Africa and some parts of Asia. This shortage has not only considerably constrained the achievement of health-related development goals but also impeded accelerated progress towards universal health coverage (UHC). Like any other low-income country, Kenya is experiencing health workforce shortage particularly in specialized healthcare workers to cater for the rapidly growing need for specialized health care (MOH Training Needs Assessment report (2015))...
December 1, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/29190627/gender-related-differences-and-short-term-outcome-of-stroke-results-from-a-hospital-based-registry-in-sub-saharan-africa
#12
Yacouba Njankouo Mapoure, Ngowo Lydia Eyambe, Anastase Tamdja Dzudie, Chia Mark Ayeah, Hamadou Ba, Romuald Hentchoya, Henry Namme Luma
BACKGROUND: Studies suggest that sex differences have an impact on patients with stroke, but existing data in Africa remain inconclusive about this inference. OBJECTIVES: To study sex differences in terms of the clinical profile and short-term outcome of stroke in the Douala General Hospital, Cameroon. METHODS: A hospital-based prospective cohort study was carried out in a tertiary care hospital over an 8-year period, which included all patients admitted for confirmed acute stroke...
November 30, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/29190114/the-scientific-basis-for-healthful-carbohydrate-profile
#13
Lisa M Lamothe, Kim-Anne Lê, Rania Abou Samra, Olivier Roger, Hilary Green, Katherine Macé
Dietary guidelines indicate that complex carbohydrates should provide around half of the calories in a balanced diet, while sugars (i.e., simple carbohydrates) should be limited to no more than 5-10% of total energy intake. To achieve this public health goal a collective effort from different entities including governments, food & beverage industries and consumers is required. Some food companies have committed to continually reduce sugars in their products. Different solutions can be used to replace sugars in food products but it is important to ensure that these solutions are more healthful than the sugars they replace...
November 30, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29183092/-methamphetamine-consumption-during-pregnancy-and-its-effects-on-neonates
#14
Alina Pflügner, Ulrich Thome, Matthias K Bernhard, Mandy Vogel, Annett Bläser, Petra Nickel, Wieland Kiess
Objective Methamphetamine (MA) has become one of the most commonly used illegal drugs during pregnancy. We sought to determine how MA abuse modifies pregnancy outcomes and the health of the newborn infants. Patients 102 newborns from mothers with antenatal MA consumption were admitted to the University Hospital Leipzig from 2004-2015. Methods The effects of MA abuse on pregnancy outcomes and neonates were researched in a retrospective controlled study. We analysed the date of pregnancy detection, number of antenatal preventive examinations, body measurements of the neonates, duration of hospitalization, rate of preterm infants, congenital malformations and symptoms of neonatal abstinence syndrome...
November 28, 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29175804/review-medicinal-plants-combating-against-hypertension-a-green-antihypertensive-approach
#15
Sabira Sultana, Hafiz Muhammad Asif
Hypertension (HTN) or high blood pressure is a medical condition that accounts 9.4 million deaths all over the world every year. It is leading cause of morbidity and mortality worldwide. It increases the risk of cardiovascular diseases, including heart failure, diffuse atherosclerosis, cognitive impairment and dementia. Clinically, synthetic antihypertensive drugs have been used to treat hypertension. However, the efficacy of these drugs is low and also produces side effects which include dry mouth, dizziness, emotional distress, gastrointestinal disturbance, visual disorders etc...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29174028/inflammation-in-metabolically-healthy-and-metabolically-abnormal-adolescents-the-helena-study
#16
E M González-Gil, C Cadenas-Sanchez, J Santabárbara, G Bueno-Lozano, I Iglesia, M González-Gross, D Molnar, F Gottrand, S De Henauw, A Kafatos, K Widhalm, Y Manios, A Siani, F Amaro-Gahete, A I Rupérez, D Cañada, L Censi, M Kersting, J Dallongeville, A Marcos, F B Ortega, L A Moreno
BACKGROUND AND AIMS: Inflammation may influence the cardio-metabolic profile which relates with the risk of chronic diseases. This study aimed to assess the inflammatory status by metabolic health (MH)/body mass index (BMI) category and to assess how inflammatory markers can predict the cardio-metabolic profile in European adolescents, considering BMI. METHODS AND RESULTS: A total of 659 adolescents (295 boys) from a cross-sectional European study were included...
October 13, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29173237/deficiency-of-essential-dietary-n-3-pufa-disrupts-the-caecal-microbiome-and-metabolome-in-mice
#17
Ruairi C Robertson, Clara Seira Oriach, Kiera Murphy, Gerard M Moloney, John F Cryan, Timothy G Dinan, R P Ross, Catherine Stanton
n-3 PUFA are lipids that play crucial roles in immune-regulation, cardio-protection and neurodevelopment. However, little is known about the role that these essential dietary fats play in modulating caecal microbiota composition and the subsequent production of functional metabolites. To investigate this, female C57BL/6 mice were assigned to one of three diets (control (CON), n-3 supplemented (n3+) or n-3 deficient (n3-)) during gestation, following which their male offspring were continued on the same diets for 12 weeks...
December 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/29172750/parallel-short-forms-for-the-assessment-of-activities-of-daily-living-in-cardiovascular-rehabilitation-patients-padl-cardio-development-and-validation
#18
Andreas Schmucker, Birgit Abberger, Maren Boecker, Harald Baumeister
PURPOSE: To develop and validate parallel short forms for the assessment of activities of daily living in cardiac rehabilitation patients (PADL-cardio I & II). METHOD: PADL-cardio I & II were developed based on a sample of 106 patients [mean age  =  57.6; standard deviation (SD) = 11.1; 72.6% males] using Rasch analysis and validated with a sample of 81 patients (mean age  =  59.1; SD  =  11.1; 88.9% males). All patients answered PADL-cardio and the Short Form 12 Health Survey...
November 26, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29170698/effects-of-the-boy-scouts-of-america-personal-fitness-merit-badge-on-cardio-metabolic-risk-health-related-fitness-and-physical-activity-in-adolescent-boys
#19
Justin Maxwell, Ryan D Burns, Timothy A Brusseau
A growing number of adolescents are more sedentary and have fewer formal opportunities to participate in physical activity. With the mounting evidence that sedentary time has a negative impact on cardiometabolic profiles, health related fitness and physical activity, there is a pressing need to find an affordable adolescent physical activity intervention. One possible intervention that has been overlooked in the past is Boy Scouts of America. There are nearly 900,000 adolescent boys who participate in Boy Scouts in the United States...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/29170061/the-association-between-muscle-mass-deficits-and-arterial-stiffness-in-middle-aged-men
#20
I J Im, H J Choi, S M Jeong, H J Kim, J S Son, H J Oh
BACKGROUND AND AIMS: Early diagnosis of arteriosclerosis is fundamental for the prevention of cardiovascular morbidity and mortality. The current study was performed to identify major predictors of arteriosclerosis and to assess the association between arterial stiffness as measured by cardio-ankle vascular index (CAVI) and muscle mass deficit (MMD) estimated by bioelectrical impedance analysis (BIA) in middle-aged men. METHODS AND RESULTS: Data were gathered from 3356 middle-aged men who visited a health promotion center...
October 12, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
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