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https://www.readbyqxmd.com/read/28545937/treatment-of-nafld-with-diet-physical-activity-and-exercise
#1
REVIEW
Manuel Romero-Gómez, Shira Zelber-Sagi, Michael Trenell
Lifestyle intervention can be useful across all the spectrum of NAFLD patients. Losing weight decreases cardiovascular / diabetes risk and also regresses liver disease. Weight reductions of ≥ 10% are required for inducing near universal NASH resolution or fibrosis improvement by at least one stage. However, modest weight losses (>5%) also produce important benefits on NAS and its components. In addition, to improve the success of this intervention we need to explore, beyond total calories and type of weight loss diet, the role of micro and macronutrients, evidence-based benefits of physical activity and exercise and finally supporting these modifications through established behaviour change models and techniques...
May 22, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28545656/cord-plasma-insulin-and-in-utero-exposure-to-ambient-air-pollution
#2
Narjes Madhloum, Bram G Janssen, Dries S Martens, Nelly D Saenen, Esmée Bijnens, Wilfried Gyselaers, Joris Penders, Charlotte Vanpoucke, Wouter Lefebvre, Michelle Plusquin, Tim S Nawrot
INTRODUCTION: Cardio-metabolic risk factors including insulin levels are at young age barely perceived as harmful, but over time these risk factors may track and lead to higher risk of metabolic syndrome. Studies showed that exposure to air pollution is associated with an increased risk of insulin resistance in childhood. We determined whether the origin of type 2 diabetes can be found in the early childhood by examining the levels of insulin in the neonatal cord blood and whether this can be considered as a disease marker for later life...
May 22, 2017: Environment International
https://www.readbyqxmd.com/read/28538025/a-cluster-rct-to-reduce-workers-sitting-time-impact-on-cardiometabolic-biomarkers
#3
Genevieve N Healy, Elisabeth Ah Winkler, Elizabeth G Eakin, Neville Owen, Anthony D LaMontagne, Marj Moodie, David W Dunstan
PURPOSE: To evaluate the initial and long-term impacts on cardio-metabolic health indicators of the Stand Up Victoria intervention - a 12-month, multicomponent workplace-delivered intervention that successfully reduced overall sitting time, primarily by increasing standing time. METHODS: Office worksites (≥1km apart) from a single organization were cluster randomized to intervention (n=7) or control (n=7). Participants were 136 intervention and 95 control desk-based workers (5-39 per worksite; 68% women; mean±SD age = 45...
May 22, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28526006/cardiometabolic-profile-of-obese-children-in-a-sub-saharan-african-setting-a-cross-sectional-study
#4
Eunice Chedjou-Nono, Suzanne Sap, Simeon-Pierre Choukem, Issa Ngosso Tetanye, Daniel Nebongo, Olivier Koki Ndombo
BACKGROUND: Cardiovascular and metabolic consequences of obesity in children, unlike adults, are still not well understood nor have they been subject to extensive research in Africa. We aimed to identify the cardio-metabolic complications associated with childhood obesity at the early phase of the management of obese children in a reference center in Cameroon. METHODS: In this cross-sectional study conducted from November 2013 to September 2014 and based on World Health Organization (WHO) classification of Obesity (BMI > 3SD under 5 years and BMI > 2SD from 5 and above), we included children aged 3 to 17 years who were being followed up for obesity at the pediatric endocrinology unit of the Mother and Child Center of the Chantal BIYA Foundation in Yaounde, Cameroon...
May 19, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28505345/cardio-oncology-a-multidisciplinary-approach-for-detection-prevention-and-management-of-cardiac-dysfunction-in-cancer-patients
#5
Kazuko Tajiri, Kazutaka Aonuma, Ikuo Sekine
Cardiac dysfunction that develops during or after completion of cancer therapy is a growing health concern that should be addressed in a multidisciplinary setting. Cardio-oncology is a new discipline that focuses on screening, monitoring and treating cardiovascular disease during and after cancer treatment. A baseline cardiovascular risk assessment is essential. For high-risk patients, a tailored and detailed plan for cardiovascular management throughout treatment and beyond should also be established. Anthracycline and/or trastuzumab-containing chemotherapy and chest-directed radiation therapy are well known cardiotoxic cancer therapies...
May 15, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28499768/mortality-in-people-with-psychotic-disorders-in-finland-a-population-based-13-year-follow-up-study
#6
Jaakko Keinänen, Outi Mantere, Niina Markkula, Krista Partti, Jonna Perälä, Samuli I Saarni, Tommi Härkänen, Jaana Suvisaari
OBJECTIVES: We conducted a population based study aiming at finding predictors of mortality in psychotic disorders and evaluating the extent to which sociodemographic, lifestyle and health-related factors explain the excess mortality. METHODS: In a nationally representative sample of Finns aged 30-70years (n=5642), psychotic disorders were diagnosed using structured interviews and medical records in 2000-2001. Information on mortality and causes of death was obtained of those who died by the end of year 2013...
May 9, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28499105/whether-low-volume-alcohol-use-is-cardio-protective-is-important-for-public-health-policy-so-the-available-evidence-deserves-critical-analysis-the-authors-respond
#7
Tim Stockwell, Jinhui Zhao, Tanya Chikritzhs
No abstract text is available yet for this article.
May 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28499102/alcohol-consumption-and-mortality-from-coronary-heart-disease-an-updated-meta-analysis-of-cohort-studies
#8
Jinhui Zhao, Tim Stockwell, Audra Roemer, Timothy Naimi, Tanya Chikritzhs
OBJECTIVE: Previous meta-analyses estimate that low-volume alcohol consumption protects against coronary heart disease (CHD). Potential errors in studies include systematic misclassification of drinkers as abstainers, inadequate measurement, and selection bias across the life course. METHOD: Prospective studies of alcohol consumption and CHD mortality were identified in scholarly databases and reference lists. Studies were coded for potential abstainer biases and other study characteristics...
May 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28497385/associations-of-human-skeletal-muscle-fiber-type-and-insulin-sensitivity-blood-lipids-and-vascular-hemodynamics-in-a-cohort-of-premenopausal-women
#9
Gordon Fisher, Samuel T Windham, Perry Griffin, Jonathan L Warren, Barbara A Gower, Gary R Hunter
PURPOSE: Cardiometabolic disease remains a leading cause of morbidity and mortality in developed nations. Consequently, identifying and understanding factors associated with underlying pathophysiological processes leading to chronic cardio metabolic conditions is critical. Metabolic health, arterial elasticity, and insulin sensitivity (SI) may impact disease risk, and may be determined in part by myofiber type. Therefore, the purpose of this study was to test the hypothesis that type I myofiber composition would be associated with high SI, greater arterial elasticity, lower blood pressure, and blood lipids; whereas, type IIx myofibers would be associated with lower SI, lower arterial elasticity, higher blood pressure, blood lipids...
May 11, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28488901/association-of-shiftwork-and-immune-cells-among-police-officers-from-the-buffalo-cardio-metabolic-occupational-police-stress-study
#10
Michael D Wirth, Michael E Andrew, Cecil M Burchfiel, James B Burch, Desta Fekedulegn, Tara A Hartley, Luenda E Charles, John M Violanti
Shift workers suffer from a constellation of symptoms associated with disruption of circadian rhythms including sleep abnormalities, and abnormal hormone secretion (e.g. melatonin, cortisol). Recent, but limited, evidence suggests that shift workers have elevated levels of circulating white blood cells (WBCs) compared to their day working counterparts. Interestingly, recent reviews highlight the strong linkage between the immune system and circadian rhythms which includes, but is not limited to, circulating cell populations and functions...
May 10, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28486177/depressive-symptom-profiles-cardio-metabolic-risk-and-inflammation-results-from-the-midus-study
#11
Diana A Chirinos, Kyle W Murdock, Angie S LeRoy, Christopher Fagundes
BACKGROUND: This study aimed to (1) provide a comprehensive characterization of depressive symptoms profiles, and (2) examine the cross-sectional association between depressive symptom profiles and cardio-metabolic outcomes, including metabolic syndrome and obesity, while controlling for sociodemographic variables, health behaviors and inflammation. METHODS: Our sample was comprised of 1085 participants (55.80% female) enrolled in the MIDUS-II biomarker study. Latent profile analysis (LPA) was used to derive depressive symptom profiles using subscales of the Mood and Anxiety Symptom Questionnaire (MASQ) and the Center for Epidemiologic Studies Depression Scale (CES-D) subscales as well as Pittsburgh Sleep Quality Index (PSQI) global score...
April 29, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28481126/increased-levels-of-alveolar-and-airway-exhaled-nitric-oxide-in-runners
#12
Alexandra Thornadtsson, Nikola Drca, Fabio Ricciardolo, Marieann Högman
AIM: The objective of this study was to apply extended NO analysis for measurements of NO dynamics in the lung, divided into alveolar and airway contribution, in amateur runners and marathoners. METHODS: The athletes participated in either a marathon or a half marathon. The athletes self-reported their age, weight, height, training distance per week, competing distance, cardio-pulmonary health, atopic status, and use of tobacco. Measurements of exhaled NO (FENO) with estimation of alveolar NO (CANO) and airway flux (JawNO), ventilation, pulse oximetry, and peak flow were performed before, immediately after, and 1 hour after completing the race...
May 8, 2017: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/28480689/habitually-increasing-physical-activity-in-daily-life-during-8-week-intervention-reduces-arterial-stiffness-in-older-women-a-community-based-pilot-study
#13
Masato Nishiwaki, Mami Fujibayashi, Chika Nanayama, Noriko Ogawa, Isako Itakura, Naoyuki Matsumoto
BACKGROUND: The recent Japanese official physical activity (PA) guidelines for health promotion recommend increasing PA by 10 minutes per day (Plus 10), which generally corresponds to about 1,000 steps per day. However, whether habitually increasing PA in daily life improves arterial stiffness in older people is unclear. The present study aimed to examine the effects of habitually increasing PA during an intervention on arterial stiffness in older women. METHODS: Twenty-one older women (age, 76 ± 1 years) participated in supervised group activity and seated exercise for 60 min per session, once each week during an 8-week intervention...
May 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28472516/-one-day-i-will-find-the-right-words-and-they-will-be-simple-rethinking-dnacpr-at-a-national-level
#14
Therese Callus
Evidence has shown a diversity of practices and terminology concerning the implementation and documentation of Do Not Attempt Cardio-Pulmonary Resuscitation (DNACPR) notices across different hospital Trusts in England and Wales, and the Resuscitation Council (UK) has recently proposed a standard approach for how DNACPR notices can be better incorporated into overall care plans. However, the Council can only make recommendations for good practice. This discussion reviews current practices and suggests that the time has come for a national standardized approach to the process of initiating and documenting DNACPR, along with a dedicated programme to increase public understanding of what is involved...
May 2, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28469492/diagnostic-strategies-for-early-recognition-of-cancer-therapeutics-related-cardiac-dysfunction
#15
REVIEW
Carlos R Manrique, Michael Park, Nidhish Tiwari, Juan Carlos Plana, Mario J Garcia
Cardiovascular toxicity in the form of cardiac dysfunction continues to be an obstacle for patients with cancer. Survival and quality of life of cancer survivors are frequently affected by increased incidence of cardiovascular disease. The involvement of the cardiovascular system by primary or secondary malignancies, as well as its dysfunction secondary to the administration of antineoplastics, has led to the development of a new discipline called Cardio-Oncology, an exciting cardiology subspecialty with more questions than answers and as a result an enormous opportunity for research in the field...
2017: Clinical Medicine Insights. Cardiology
https://www.readbyqxmd.com/read/28463098/when-is-a-cardiac-arrest-non-cardiac
#16
Ryan M Carter, David C Cone
Introduction While the overall survival rate for out-of-hospital cardiac arrest (OHCA) is low, ranging from 5%-10%, several characteristics have been shown to decrease mortality, such as presence of bystander cardiopulmonary resuscitation (CPR), witnessed vs unwitnessed events, and favorable initial rhythm (VF/VT). More recently, studies have shown that modified CPR algorithms, such as chest-compression only or cardio-cerebral resuscitation, can further increase survival rates in OHCA. Most of these studies have included only OHCA patients with "presumed cardiac etiology," on the assumption that airway management is of lesser impact than chest compressions in these patients...
May 2, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28460714/core-outcome-sets-for-research-and-clinical-practice
#17
REVIEW
Alessandro Chiarotto, Raymond W Ostelo, Dennis C Turk, Rachelle Buchbinder, Maarten Boers
BACKGROUND: This masterclass introduces the topic of core outcome sets, describing rationale and methods for developing them, and providing some examples that are relevant for clinical research and practice. METHOD: A core outcome set is a minimum consensus-based set of outcomes that should be measured and reported in all clinical trials for a specific health condition and/or intervention. Issues surrounding outcome assessment, such as selective reporting and inconsistency across studies, can be addressed by the development of a core set...
March 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/28459794/effectiveness-of-a-16-week-high-intensity-cardio-resistance-training-hicrt-program-in-adults
#18
Tina A Greenlee, Daniel R Greene, Nathan J Ward, Ginger E Reeser, Courtney M Allen, Nicholas W Baumgartner, Neal J Cohen, Arthur F Kramer, Charles H Hillman, Aron K Barbey
The purpose of this study was to determine the efficacy of a novel, 16-week High-Intensity Cardio-Resistance Training (HICRT) program on measures of aerobic fitness, agility, aerobic power, muscular endurance, lower body explosive power, and self-reported activity level. The intervention group (N=129; 63 f, 24.65±5.55 y) had a baseline VO2max of 39.83±9.13. These individuals participated in 26, 70-minute exercise sessions, and 4 fitness testing sessions. Participants were matched with a non-exercise control group, paired by sex, age, and baseline VO2max...
April 26, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28458804/nutrition-pharmacological-and-training-strategies-adopted-by-six-bodybuilders-case-report-and-critical-review
#19
Paulo Gentil, Claudio Andre Barbosa de Lira, Antonio Paoli, José Alexandre Barbosa Dos Santos, Roberto Deivide Teixeira da Silva, José Romulo Pereira Junior, Edson Pereira da Silva, Rodrigo Ferro Magosso
The purpose of this study was to report and analyze the practices adopted by bodybuilders in light of scientific evidence and to propose evidence-based alternatives. Six (four male and two female) bodybuilders and their coaches were directly interviewed. According to the reports, the quantity of anabolic steroids used by the men was 500-750 mg/week during the bulking phase and 720-1160 mg during the cutting phase. The values for women were 400 and 740 mg, respectively. The participants also used ephedrine and hydrochlorothiazide during the cutting phase...
February 24, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/28456149/plasma-chemerin-in-young-untrained-men-association-with-cardio-metabolic-traits-and-physical-performance-and-response-to-intensive-interval-training
#20
Nejmeddine Ouerghi, Mohamed Kacem Ben Fradj, Marwa Khammassi, Moncef Feki, Naziha Kaabachi, Anissa Bouassida
OBJECTIVES: Chemerin is an adipose tissue-derived adipokine thought to decrease insulin sensitivity and increase cardiometabolic risk. This study aimed to assess the association of chemerin with cardiometabolic risk and physical performance and examine its response to high-intensity interval training (HIIT). METHODS: Eighteen young men have been applied a HIIT program during 8 weeks. Plasma chemerin together with several cardiometabolic factors and physical performance indices were determined before and after the training program...
February 15, 2017: Neuro Endocrinology Letters
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