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https://www.readbyqxmd.com/read/28343261/stress-processes-linking-parent-child-disconnection-to-disease-risk-in-young-adulthood-amplification-by-genotype
#1
Dayoung Bae, Kandauda A S Wickrama
Previous studies have documented that early stressful family relationships influence subsequent stressful life circumstances and health outcomes over the life course. Less is known, however, about whether stressful parent-child relationships increase the influence of proximal stressors on youth health operating as a stress-sensitizing life context, and individual genetic variations have effects on these developmental processes. Informed by life course stress process theory, which focuses on the proliferation, accumulation, and interactions of stressors over the life course as health risks, we examined whether (a) parent-child disconnection influences the occurrence of stressful life events in young adulthood, (b) parent-child disconnection potentiates the impact of stressful life events on young adults' health, or (c) potential health impact is intensified further by individual genotype...
March 25, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28337823/interest-of-the-trajectory-method-for-the-evaluation-of-outcomes-after-in-utero-drug-exposure-example-of-anxiolytics-and-hypnotics
#2
Caroline Hurault-Delarue, Cécile Chouquet, Nicolas Savy, Isabelle Lacroix, Anna-Belle Beau, Jean-Louis Montastruc, Christine Damase-Michel
PURPOSE: The aim of this study was to examine the potential benefit to take into account duration and intensity of drug exposure using the recently published method based on individual drug trajectories. This approach was used to define profiles of exposure to anxiolytics/hypnotics during pregnancy and to evaluate the potential effect on newborn health. METHODS: The study was performed in EFEMERIS database (54 918 mother-children pairs). An estimation of adaptation to extrauterine life was assessed using several criteria especially cardio-respiratory symptoms...
March 24, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28335768/leisure-sedentary-time-is-differentially-associated-with-hypertension-diabetes-mellitus-and-hyperlipidemia-depending-on-occupation
#3
Man Sup Lim, Bumjung Park, Il Gyu Kong, Songyong Sim, So Young Kim, Jin-Hwan Kim, Hyo Geun Choi
BACKGROUND: Sedentary behavior is considered an independent cause of cardio-metabolic diseases, regardless of physical activity level and obesity. Few studies have reported the association between leisure sedentary time and cardio-vascular diseases in terms of occupation. METHODS: We performed a cross-sectional study using data from the Korean Community Health Survey (KCHS) for 240,086 participants assessed in 2011 and 2013. Occupation was categorized into four groups: farmer or fisherman, laborer, and soldier (Group I); service worker, salesperson, technician, mechanic, production worker, and engineer (Group II); manager, expert, specialist, and clerk (Group III); and unemployed (Group IV)...
March 23, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28330818/cardio-onco-hematology-in-clinical-practice-position-paper-and-recommendations
#4
Teresa López-Fernández, Ana Martín García, Ana Santaballa Beltrán, Ángel Montero Luis, Ramón García Sanz, Pilar Mazón Ramos, Sonia Velasco Del Castillo, Esteban López de Sá Areses, Manuel Barreiro-Pérez, Rocío Hinojar Baydes, Leopoldo Pérez de Isla, Silvia Cayetana Valbuena López, Regina Dalmau González-Gallarza, Francisco Calvo-Iglesias, Juan José González Ferrer, Antonio Castro Fernández, Eva González-Caballero, Cristina Mitroi, Meritxell Arenas, Juan Antonio Virizuela Echaburu, Pascual Marco Vera, Andrés Íñiguez Romo, José Luis Zamorano, Juan Carlos Plana Gómez, José Luis López Sendón Henchel
Improvements in early detection and treatment have markedly reduced cancer-related mortality. However survival not only depends on effectively cure cancer, but prevention, diagnosis and treatment of cancer-related complications is also needed. Cardiovascular toxicity is a widespread problem across many classes of therapeutic schemes, however scientific evidence in the management of cardiovascular complications of onco-hematological patients is scarce, as these patients have been systematically excluded from clinical trials and current recommendations are based on expert consensus...
March 18, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28330611/rationale-for-cardio-oncology-units
#5
Lara F Nhola, Hector R Villarraga
With the rapidly rising number of patients surviving cancer, often in the setting of new or pre-existing cardiovascular disease and risk factors, a need has arisen for a specialty within the realm of cardiovascular care that can evaluate and manage these patients along with our colleagues in oncology and hematology. By the same token, all health care providers involved in the care of cancer patients with heart disease must be fully aware of the impact of adverse cardiovascular effects on the survival of these patients...
March 16, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28330412/early-asymmetric-cardio-cerebral-causality-and-outcome-after-severe-traumatic-brain-injury
#6
Lei Gao, Peter Smieleweski, Marek Czosnyka, Ari Ercole
The brain and heart are two vital systems in health and disease, increasingly recognised as a complex, interdependent network with constant information flow in both directions. After severe traumatic brain injury (TBI), the causal, directed interactions between the brain, heart and autonomic nervous system have not been well established. Novel methods are needed to probe unmeasured, potentially prognostic information in complex biological networks that are not revealed via traditional means. In this study, we examined potential bi-directional causality between intracranial pressure (ICP), mean arterial pressure (MAP) and heart rate (HR) and its relationship to mortality in a 24-hour period early after TBI...
March 23, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28327645/a-novel-point-of-care-smartphone-based-system-for-monitoring-the-cardiac-and-respiratory-systems
#7
Kwanghyun Sohn, Faisal M Merchant, Omid Sayadi, Dheeraj Puppala, Rajiv Doddamani, Ashish Sahani, Jagmeet P Singh, E Kevin Heist, Eric M Isselbacher, Antonis A Armoundas
Cardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called "cvrPhone"), and an application to assess underlying ischemia, and estimate the respiration rate (RR) and tidal volume (TV) from analysis of electrocardiographic (ECG) signals only. During in-vivo swine studies (n = 6), 12-lead ECG signals were recorded at baseline and following coronary artery occlusion...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28321925/effects-of-6-months-aerobic-interval-training-on-skeletal-muscle-metabolism-in-middle-aged-metabolic-syndrome-patients
#8
A Guadalupe-Grau, V E Fernández-Elías, J F Ortega, F Dela, J W Helge, R Mora Rodríguez
AIM: Aerobic interval training (AIT) improves the health of metabolic syndrome patients (MetS) more than moderate intensity continuous training. However, AIT has not been shown to reverse all metabolic syndrome risk factors, possibly due to the limited duration of the training programs. PURPOSE: To assess the effects of 6 months of AIT on cardio-metabolic health and muscle metabolism in middle aged MetS. METHODS: Eleven MetS (54.5 ± 0.7 yrs old) underwent 6 month of 3 days a week supervised AIT program on a cycle-ergometer...
March 21, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28288564/allopurinol-use-and-the-risk-of-acute-cardiovascular-events-in-patients-with-gout-and-diabetes
#9
Jasvinder A Singh, Rekha Ramachandaran, Shaohua Yu, Jeffrey R Curtis
BACKGROUND: Few studies, if any, have examined cardiovascular outcomes in patients with diabetes and gout. Both diabetes and gout are risk factors for cardiovascular disease. The objective of this study was to examine the effect of allopurinol on the risk of incident acute cardiovascular events in patients with gout and diabetes. METHODS: We used the 2007-2010 Multi-Payer Claims Database (MPCD) that linked health plan data from national commercial and governmental insurances, representing beneficiaries with United Healthcare, Medicare, or Medicaid coverage...
March 14, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28283121/health-care-expenditures-associated-with-pollution-exploratory-methods-and-findings
#10
Alexander S Preker, Olusoji O Adeyi, Marisa Gil Lapetra, Diane-Charlotte Simon, Eric Keuffel
BACKGROUND: The research done for this paper is part of the background analysis undertaken to support the work of the Global Commission on Pollution, Health and Development, an initiative of The Lancet, the Global Alliance on Health and Pollution, and the Icahn School of Medicine at Mount Sinai. The paper expands on areas where the current literature has gaps in knowledge related to the health care cost of pollution. OBJECTIVES: This study aims to generate an initial estimate of total tangible health care expenditure attributable to man-made pollution affecting air, soil and water...
September 2016: Annals of Global Health
https://www.readbyqxmd.com/read/28282433/the-cause-specific-morbidity-and-mortality-and-referral-patterns-of-all-neonates-admitted-to-a-tertiary-referral-hospital-in-the-northern-provinces-of-vietnam-over-a-one-year-period
#11
Merinda Miles, Khu Thi Khanh Dung, Le Thi Ha, Nguyen Thanh Liem, Khu Ha, Rod W Hunt, Kim Mulholland, Chris Morgan, Fiona M Russell
OBJECTIVE: To describe the cause-specific morbidity and mortality, and referral patterns of all neonates admitted to a tertiary referral hospital in the northern provinces of Vietnam. DESIGN: A prospective hospital based observational study. SETTING: The Neonatal Department, National Hospital of Pediatrics, Hanoi, Vietnam. PATIENTS: All admissions to the Neonatal Department over a 12 month period. MAIN OUTCOME MEASURES: Cause-specific morbidity and mortality; deaths...
2017: PloS One
https://www.readbyqxmd.com/read/28279424/cardio-oncology-the-role-of-big-data
#12
REVIEW
Anant Mandawat, Andrew E Williams, Sanjeev A Francis
Despite its challenges, a "big data" approach offers a unique opportunity within the field of cardio-oncology. A pharmacovigilant approach using large data sets can help characterize cardiovascular toxicities of the rapidly expanding armamentarium of targeted therapies. Creating a broad coalition of data sharing can provide insights into the incidence of cardiotoxicity and stimulate research into the underlying mechanisms. Population health necessitates the use of big data and can help inform public health interventions to prevent both cancer and cardiovascular disease...
April 2017: Heart Failure Clinics
https://www.readbyqxmd.com/read/28269565/evaluating-respiratory-muscle-activity-using-a-wireless-sensor-platform
#13
Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane
Wireless sensors are an emerging technology that allows to assist physicians in the monitoring of patients health status. This approach can be used for the non-invasive recording of the electrical respiratory muscle activity of the diaphragm (EMGdi). In this work, we acquired the EMGdi signal of a healthy subject performing an inspiratory load test. To this end, the EMGdi activity was captured from a single channel of electromyography using a wireless platform which was compared with the EMGdi and the inspiratory mouth pressure (Pmouth) recorded with a conventional lab equipment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263284/replacement-effects-of-sedentary-time-on-metabolic-outcomes-the-maastricht-study
#14
Julianne D van der Berg, Jeroen Hpm van der Velde, Ellis Ac de Waard, Hans Bosma, Hans Hcm Savelberg, Nicolaas C Schaper, Joop Pw van den Bergh, Piet Pmm Geusens, Miranda T Schram, Simone Js Sep, Carla Jh van der Kallen, Ronald Ma Henry, Pieter C Dagnelie, Simone Jpm Eussen, Martien Cjm van Dongen, Sebastian Köhler, Abraham A Kroon, Coen DA Stehouwer, Annemarie Koster
INTRODUCTION: Sedentary time has been associated with detrimental health effects, so in some countries guidelines to reduce sedentary time have been developed. As reducing sedentary time inevitably results in more non-sedentary time, effects of this reduction may depend on the activity with which it is replaced. PURPOSE: To examine associations of theoretical reallocations of sedentary time to standing or stepping with cardio-metabolic outcomes and type 2 diabetes...
March 3, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28241983/unraveling-the-metabolic-health-benefits-of-fasting-related-to-religious-beliefs-a-narrative-review
#15
REVIEW
Angeliki Persynaki, Spyridon Karras, Claude Pichard
Periodic fasting, under a religious aspect, has been adopted by humans for centuries as a crucial pathway of spiritual purification. Caloric restriction, with or without exclusion of certain types of food, is often a key component. Fasting varies significantly among different populations according to cultural habits and local climate conditions. Religious fasting in terms of patterns (continuous versus intermittent) and duration can vary from 1 to 200 d; thus, the positive and negative impact on health can be considerable...
March 2017: Nutrition
https://www.readbyqxmd.com/read/28239481/effectiveness-of-workers-general-health-examination-in-korea-by-health-examination-period-and-compliance-retrospective-cohort-study-using-nationwide-data
#16
Huisu Eom, Jun-Pyo Myong, Eun-A Kim, Bohwa Choi, Soon Woo Park, Young Joong Kang
BACKGROUND: Our study evaluated the effectiveness of the Workers' General Health Examination by health examination period and compliance. METHODS: A retrospective cohort of the health examination participants in 2006 (baseline year: N = 6,527,045) was used. We identified newly occurring cardio-cerebrovascular disease over 7 years (from 2007 to 2013). After stratification by age, sex, and national health insurance type, we identified 7 years' cumulative incidence of cardio-cerebrovascular disease by health examination compliance and estimated its relative risk by health examination period and compliance...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28239402/high-cholesterol-diet-does-not-alter-gut-microbiota-composition-in-mice
#17
Lidiya G Dimova, Nikola Zlatkov, Henkjan J Verkade, Bernt Eric Uhlin, Uwe J F Tietge
INTRODUCTION: Western diet containing both saturated fat and cholesterol impairs cardio-metabolic health partly by modulating diversity and function of the microbiota. While diet containing only high fat has comparable effects, it is unclear how diets only enriched in cholesterol impact the microbiota. Therefore, we aimed to characterize the response of host and microbiota to a high cholesterol (HC) diet in mice susceptible to cardio-metabolic disease. METHODS: LDLR knockout mice received either 1...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28227820/evaluating-respiratory-muscle-activity-using-a-wireless-sensor-platform
#18
Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane, Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane, Raimon Jane, Luis Estrada, Leonardo Sarlabous, Abel Torres
Wireless sensors are an emerging technology that allows to assist physicians in the monitoring of patients health status. This approach can be used for the non-invasive recording of the electrical respiratory muscle activity of the diaphragm (EMGdi). In this work, we acquired the EMGdi signal of a healthy subject performing an inspiratory load test. To this end, the EMGdi activity was captured from a single channel of electromyography using a wireless platform which was compared with the EMGdi and the inspiratory mouth pressure (Pmouth) recorded with a conventional lab equipment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224294/cardio-metabolic-risk-factors-in-youth-with-classical-21-hydroxylase-deficiency
#19
Kansuda Ariyawatkul, Supatporn Tepmongkol, Suphab Aroonparkmongkol, Taninee Sahakitrungruang
Patients with congenital adrenal hyperplasia (CAH) appear to have adverse cardiovascular risk profile and other long-term health problems in adult life, but there are limited data in young CAH patients. We aim to evaluate the cardio-metabolic risk factors in adolescents and young adults with classical 21-hydroxylase deficiency (21-OHD). We performed a cross-sectional study of 21 patients (17 females) with classic CAH detected clinically and not through newborn screening, aged 15.2 ± 5.8 years, and 21 healthy matched controls...
February 21, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28211649/insufficient-sleep-in-adolescents-causes-and-consequences
#20
Judith A Owens, Miriam R Weiss
Insufficient sleep poses an important and complicated set of health risks in the adolescent population. Not only is deficient sleep (defined as both sleep duration inadequate to meet sleep needs and sleep timing misaligned with the body's circadian rhythms) at epidemic levels in this population, but the contributing factors are both complex and numerous and there are a myriad of negative physical and mental health, safety and performance consequences. Causes of inadequate sleep identified in this population include internal biological processes such as the normal shift (delay) in circadian rhythm that occurs in association with puberty and a developmentally-based slowing of the "sleep drive", and external factors including extracurricular activities, excessive homework load, evening use of electronic media, caffeine intake and early school start times...
February 17, 2017: Minerva Pediatrica
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