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https://www.readbyqxmd.com/read/29868977/role-of-additional-organ-resection-in-adrenocortical-carcinoma-analysis-of-167-patients-from-the-u-s-adrenocortical-carcinoma-database
#1
Paula Marincola Smith, Colleen M Kiernan, Thuy B Tran, Lauren M Postlewait, Shishir K Maithel, Jason Prescott, Timothy Pawlik, Tracy S Wang, Jason Glenn, Ioannis Hatzaras, Rivka Shenoy, John Phay, Lawrence A Shirley, Ryan C Fields, Linda Jin, Sharon Weber, Ahmed Salem, Jason Sicklick, Shady Gad, Adam Yopp, John Mansour, Quan-Yang Duh, Natalie Seiser, Konstantinos Votanopoulos, Edward A Levine, George Poultsides, Carmen C Solórzano
BACKGROUND: Adrenocortical carcinoma (ACC) is a rare and aggressive cancer. This report describes factors and outcomes associated with resection of extra-adrenal organs en bloc during index adrenalectomy. METHODS: Patients who underwent ACC resection for non-metastatic disease from 1993 to 2014 at 13 participating institutions of the US-ACC Group were included in the study. Factors associated with en bloc resection were assessed by uni- and multivariate analysis...
June 4, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29761515/association-of-perioperative-transfusion-with-survival-and-recurrence-after-resection-of-gallbladder-cancer-a-10-institution-study-from-the-us-extrahepatic-biliary-malignancy-consortium
#2
Alexandra G Lopez-Aguiar, Cecilia G Ethun, Mia R McInnis, Timothy M Pawlik, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza W Beal, Ioannis Hatzaras, Rivfka Shenoy, Kenneth Cardona, Shishir K Maithel
BACKGROUND AND OBJECTIVES: Perioperative blood transfusion is associated with poor outcomes in several malignancies. Its effect in gallbladder cancer (GBC) is unknown. METHODS: All patients with GBC who underwent curative-intent resection at 10-institutions from 2000 to 2015 were included. The effect of blood transfusion on overall survival (OS) and recurrence-free (RFS) was evaluated. RESULTS: Of 262 patients with curative-intent resection for GBC, 61 patients (23%) received blood transfusions...
May 14, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29470820/the-impact-of-intraoperative-re-resection-of-a-positive-bile-duct-margin-on-clinical-outcomes-for-hilar-cholangiocarcinoma
#3
Xu-Feng Zhang, Malcolm H Squires, Fabio Bagante, Cecilia G Ethun, Ahmed Salem, Sharon M Weber, Thuy Tran, George Poultsides, Andre Y Son, Ioannis Hatzaras, Linda Jin, Ryan C Fields, Matthew Weiss, Charles Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Carl R Schmidt, Timothy M Pawlik
BACKGROUND: The impact of re-resection of a positive intraoperative bile duct margin on clinical outcomes for resectable hilar cholangiocarcinoma (HCCA) remains controversial. We sought to define the impact of re-resection of an initially positive frozen-section bile duct margin on outcomes of patients undergoing surgery for HCCA. METHODS: Patients who underwent curative-intent resection for HCCA between 2000 and 2014 were identified at 10 hepatobiliary centers...
May 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29404753/defining-early-recurrence-of-hilar-cholangiocarcinoma-after-curative-intent-surgery-a-multi-institutional-study-from-the-us-extrahepatic-biliary-malignancy-consortium
#4
Xu-Feng Zhang, Eliza W Beal, Jeffery Chakedis, Qinyu Chen, Yi Lv, Cecilia G Ethun, Ahmed Salem, Sharon M Weber, Thuy Tran, George Poultsides, Andre Y Son, Ioannis Hatzaras, Linda Jin, Ryan C Fields, Stefan Buettner, Charles Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Carl R Schmidt, Timothy M Pawlik
BACKGROUND: Time to tumor recurrence may be associated with outcomes following resection of hepatobiliary cancers. The objective of the current study was to investigate risk factors and prognosis among patients with early versus late recurrence of hilar cholangiocarcinoma (HCCA) after curative-intent resection. METHODS: A total of 225 patients who underwent curative-intent resection for HCCA were identified from 10 academic centers in the USA. Data on clinicopathologic characteristics, pre-, intra-, and postoperative details and overall survival (OS) were analyzed...
February 5, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29306541/the-impact-of-caudate-lobe-resection-on-margin-status-and-outcomes-in-patients-with-hilar-cholangiocarcinoma-a-multi-institutional-analysis-from-the-us-extrahepatic-biliary-malignancy-consortium
#5
Neal Bhutiani, Charles R Scoggins, Kelly M McMasters, Cecilia G Ethun, George A Poultsides, Timothy M Pawlik, Sharon M Weber, Carl R Schmidt, Ryan C Fields, Kamran Idrees, Ioannis Hatzaras, Perry Shen, Shishir K Maithel, Robert C G Martin
BACKGROUND: The objective of this study was to determine the impact of caudate resection on margin status and outcomes during resection of extrahepatic hilar cholangiocarcinoma. METHODS: A database of 1,092 patients treated for biliary malignancies at institutions of the Extrahepatic Biliary Malignancy Consortium was queried for individuals undergoing curative-intent resection for extrahepatic hilar cholangiocarcinoma. Patients who did versus did not undergo concomitant caudate resection were compared with regard to demographic, baseline, and tumor characteristics as well as perioperative outcomes...
April 2018: Surgery
https://www.readbyqxmd.com/read/29284072/adjuvant-therapy-is-associated-with-improved-survival-after-curative-resection-for-hilar-cholangiocarcinoma-a-multi-institution-analysis-from-the-u-s-extrahepatic-biliary-malignancy-consortium
#6
MULTICENTER STUDY
Bradley A Krasnick, Linda X Jin, Jesse T Davidson, Dominic E Sanford, Cecilia G Ethun, Timothy M Pawlik, George A Poultsides, Thuy Tran, Kamran Idrees, William G Hawkins, William C Chapman, Maria B M Doyle, Sharon M Weber, Steven M Strasberg, Ahmed Salem, Robert C G Martin, Chelsea A Isom, Charles Scoggins, Carl R Schmidt, Perry Shen, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Shishir K Maithel, Ryan C Fields
BACKGROUND: Curative-intent treatment for localized hilar cholangiocarcinoma (HC) requires surgical resection. However, the effect of adjuvant therapy (AT) on survival is unclear. We analyzed the impact of AT on overall (OS) and recurrence free survival (RFS) in patients undergoing curative resection. METHODS: We reviewed patients with resected HC between 2000 and 2015 from the ten institutions participating in the U.S. Extrahepatic Biliary Malignancy Consortium...
March 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29205351/oncologic-effects-of-preoperative-biliary-drainage-in-resectable-hilar-cholangiocarcinoma-percutaneous-biliary-drainage-has-no-adverse-effects-on-survival
#7
Xu-Feng Zhang, Eliza W Beal, Katiuscha Merath, Cecilia G Ethun, Ahmed Salem, Sharon M Weber, Thuy Tran, George Poultsides, Andre Y Son, Ioannis Hatzaras, Linda Jin, Ryan C Fields, Matthew Weiss, Charles Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Carl R Schmidt, Timothy M Pawlik
BACKGROUND AND OBJECTIVES: The objective of the current study was to define long-term survival of patients with resectable hilar cholangiocarcinoma (HCCA) after preoperative percutaneous transhepatic biliary drainage (PTBD) versus endoscopic biliary drainage (EBD). METHODS: Between 2000 and 2014, 240 patients who underwent curative-intent resection for HCCA were identified at 10 major hepatobiliary centers. Postoperative morbidity and mortality, as well as disease-specific survival (DSS) and recurrence-free survival (RFS) were analyzed among patients...
December 4, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29169904/outcomes-after-vascular-resection-during-curative-intent-resection-for-hilar-cholangiocarcinoma-a-multi-institution-study-from-the-us-extrahepatic-biliary-malignancy-consortium
#8
Gregory V Schimizzi, Linda X Jin, Jesse T Davidson, Bradley A Krasnick, Cecilia G Ethun, Timothy M Pawlik, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Sharon M Weber, Ahmed Salem, William G Hawkins, Steven M Strasberg, Maria B Doyle, William C Chapman, Robert C G Martin, Charles Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Shishir K Maithel, Ryan C Fields
BACKGROUND: Surgical resection is the cornerstone of curative-intent therapy for patients with hilar cholangiocarcinoma (HC). The role of vascular resection (VR) in the treatment of HC in western centres is not well defined. METHODS: Utilizing data from the U.S. Extrahepatic Biliary Malignancy Consortium, patients were grouped into those who underwent resection for HC based on VR status: no VR, portal vein resection (PVR), or hepatic artery resection (HAR). Perioperative and long-term survival outcomes were analyzed...
April 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29164414/a-novel-t-stage-classification-system-for-adrenocortical-carcinoma-proposal-from-the-us-adrenocortical-carcinoma-study-group
#9
Caroline E Poorman, Cecilia G Ethun, Lauren M Postlewait, Thuy B Tran, Jason D Prescott, Timothy M Pawlik, Tracy S Wang, Jason Glenn, Ioannis Hatzaras, Rivfka Shenoy, John E Phay, Kara Keplinger, Ryan C Fields, Linda X Jin, Sharon M Weber, Ahmed Salem, Jason K Sicklick, Shady Gad, Adam C Yopp, John C Mansour, Quan-Yang Duh, Natalie Seiser, Carmen C Solórzano, Colleen M Kiernan, Konstantinos I Votanopoulos, Edward A Levine, Charles A Staley, George A Poultsides, Shishir K Maithel
BACKGROUND: The 7th AJCC T-stage system for adrenocortical carcinoma (ACC), based on size and extra-adrenal invasion, does not adequately stratify patients by survival. Lymphovascular invasion (LVI) is a known poor prognostic factor. We propose a novel T-stage system that incorporates LVI to better risk-stratify patients undergoing resection for ACC. METHOD: Patients undergoing curative-intent resections for ACC from 1993 to 2014 at 13 institutions comprising the US ACC Group were included...
February 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29064885/transplantation-versus-resection-for-hilar-cholangiocarcinoma-an-argument-for-shifting-treatment-paradigms-for-resectable-disease
#10
Cecilia G Ethun, Alexandra G Lopez-Aguiar, Douglas J Anderson, Andrew B Adams, Ryan C Fields, Maria B Doyle, William C Chapman, Bradley A Krasnick, Sharon M Weber, Joshua D Mezrich, Ahmed Salem, Timothy M Pawlik, George Poultsides, Thuy B Tran, Kamran Idrees, Chelsea A Isom, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Kenneth Cardona, Shishir K Maithel
OBJECTIVE: To investigate the influence of type of surgery (transplant vs resection) on overall survival (OS) in patients with hilar cholangiocarcinoma (H-CCA). BACKGROUND: Outcomes after resection for H-CCA are poor, yet transplantation is currently only reserved for well-selected patients with unresectable disease. METHODS: All patients with H-CCA who underwent resection from 2000 to 2015 at 10 institutions were included. Three institutions additionally had active H-CCA transplant protocols with similar selection criteria over similar time periods...
May 2018: Annals of Surgery
https://www.readbyqxmd.com/read/28986752/the-effects-of-travel-burden-on-outcomes-after-resection-of-extrahepatic-biliary-malignancies-results-from-the-us-extrahepatic-biliary-consortium
#11
Sean C O'Connor, Harveshp Mogal, Gregory Russell, Cecilia Ethun, Ryan C Fields, Linda Jin, Ioannis Hatzaras, Gerardo Vitiello, Kamran Idrees, Chelsea A Isom, Robert Martin, Charles Scoggins, Timothy M Pawlik, Carl Schmidt, George Poultsides, Thuy B Tran, Sharon Weber, Ahmed Salem, Shishir Maithel, Perry Shen
BACKGROUND: Surgical resection of extrahepatic biliary malignancies has been increasingly centralized at high-volume tertiary care centers. While this has improved outcomes overall, increased travel burden has been associated with worse survival for many other malignancies. We hypothesized that longer travel distances are associated with worse outcomes for these patients as well. STUDY DESIGN: Data was analyzed from the US Extrahepatic Biliary Consortium database, which retrospectively reviewed patients who received resection of extrahepatic biliary malignancies at 10 high-volume centers...
December 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28963709/predictors-and-prognostic-implications-of-perioperative-chemotherapy-completion-in-gastric-cancer
#12
MULTICENTER STUDY
Georgios Karagkounis, Malcolm Hart Squires, Marcovalerio Melis, George A Poultsides, David Worhunsky, Linda X Jin, Ryan C Fields, Gaya Spolverato, Timothy M Pawlik, Konstantinos I Votanopoulos, Edward A Levine, Carl Schmidt, Mark Bloomston, Clifford S Cho, Sharon Weber, Antonio Masi, Russell Berman, H Leon Pachter, Charles A Staley, Elliot Newman, Shishir K Maithel, Ioannis Hatzaras
BACKGROUND: Perioperative chemotherapy in gastric cancer is increasingly used since the "MAGIC" trial, while clinical practice data outside of trials remain limited. We sought to evaluate the predictors and prognostic implications of perioperative chemotherapy completion in patients undergoing curative-intent gastrectomy across multiple US institutions. METHODS: Patients who underwent curative-intent resection of gastric adenocarcinoma between 2000 and 2012 in eight institutions of the US Gastric Cancer Collaborative were identified...
December 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28913712/surgical-site-infection-is-associated-with-tumor-recurrence-in-patients-with-extrahepatic-biliary-malignancies
#13
MULTICENTER STUDY
Stefan Buettner, Cecilia G Ethun, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Matthew Weiss, Ryan C Fields, Bradley Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Bas Groot Koerkamp, Shishir K Maithel, Timothy M Pawlik
BACKGROUND: Surgical site infections (SSI) are one of the most common complications after hepato-pancreato-biliary surgery. Infectious complications may lead to an associated immune-modulatory effect that inhibits the body's response to cancer surveillance. We sought to define the impact of SSI on long-term prognosis of patients undergoing surgical resection of extrahepatic biliary malignancies (EHBM). METHODS: Patients undergoing surgery for EHBM between 2000 and 2014 were identified using a large, multi-center, national cohort dataset...
November 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28890310/evaluating-the-american-college-of-surgeons-national-surgical-quality-improvement-project-risk-calculator-results-from-the-u-s-extrahepatic-biliary-malignancy-consortium
#14
Eliza W Beal, Ezra Lyon, Joe Kearney, Lai Wei, Cecilia G Ethun, Sylvester M Black, Mary Dillhoff, Ahmed Salem, Sharon M Weber, Thuy B Tran, George Poultsides, Rivfka Shenoy, Ioannis Hatzaras, Bradley Krasnick, Ryan C Fields, Stefan Buttner, Charles R Scoggins, Robert C G Martin, Chelsea A Isom, Kamron Idrees, Harveshp D Mogal, Perry Shen, Shishir K Maithel, Timothy M Pawlik, Carl R Schmidt
BACKGROUND: The objective of this study is to evaluate use of the American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) online risk calculator for estimating common outcomes after operations for gallbladder cancer and extrahepatic cholangiocarcinoma. METHODS: Subjects from the United States Extrahepatic Biliary Malignancy Consortium (USE-BMC) who underwent operation between January 1, 2000 and December 31, 2014 at 10 academic medical centers were included in this study...
December 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28738949/blood-transfusion-and-survival-for-resected-adrenocortical-carcinoma-a-study-from-the-united-states-adrenocortical-carcinoma-group
#15
MULTICENTER STUDY
Caroline E Poorman, Lauren M Postlewait, Cecilia G Ethun, Thuy B Tran, Jason D Prescott, Timothy M Pawlik, Tracy S Wang, Jason Glenn, Ioannis Hatzaras, Rivfka Shenoy, John E Phay, Kara Keplinger, Ryan C Fields, Linda X Jin, Sharon M Weber, Ahmed Salem, Jason K Sicklick, Shady Gad, Adam C Yopp, John C Mansour, Quan-Yang Duh, Natalie Seiser, Carmen C Solorzano, Colleen M Kiernan, Konstantinos I Votanopoulos, Edward A Levine, Charles A Staley, George A Poultsides, Shishir K Maithel
Perioperative blood transfusion is associated with decreased survival in pancreatic, gastric, and liver cancer. The effect of transfusion in adrenocortical carcinoma (ACC) has not been studied. Patients with available transfusion data undergoing curative-intent resection of ACC from 1993 to 2014 at 13 institutions comprising the United States Adrenocortical Carcinoma Group were included. Factors associated with blood transfusion were determined. Primary and secondary end points were recurrence-free survival (RFS) and overall survival (OS), respectively...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28738935/pathologic-and-prognostic-implications-of-incidental-versus-nonincidental-gallbladder-cancer-a-10-institution-study-from-the-united-states-extrahepatic-biliary-malignancy-consortium
#16
MULTICENTER STUDY
Cecilia G Ethun, Nina Le, Alexandra G Lopez-Aguiar, Timothy M Pawlik, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Maria C Russell, Shishir K Maithel
Most gallbladder cancers (GBCs) are discovered incidentally after routine cholecystectomy. The influence of timing of diagnosis on disease stage, treatment, and prognosis is not known. Patients with GBC who underwent resection at 10 institutions from 2000 to 2015 were included. Patients diagnosed incidentally (IGBC) and nonincidentally (non-IGBC) were compared. Primary outcome was overall survival (OS). Of 445 patients with GBC, 266 (60%) were IGBC and 179 (40%) were non-IGBC. Compared with IGBC, non-IGBC patients were more likely to have R2 resections (43% vs 19%; P < 0...
July 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28549744/survival-after-resection-of-perihilar-cholangiocarcinoma-in-patients-with-lymph-node-metastases
#17
MULTICENTER STUDY
Stefan Buettner, Jeroen L A van Vugt, Marcia P Gaspersz, Robert J S Coelen, Eva Roos, Tim A Labeur, Georgios A Margonis, Cecilia G Ethun, Shishir K Maithel, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Jan N M IJzermans, Thomas M van Gulik, Timothy M Pawlik, Bas Groot Koerkamp
BACKGROUND: The aim of this study was to compare patients with PHC with lymph node metastases (LN+) who underwent a resection with patients who did not undergo resection because of locally advanced disease at exploratory laparotomy. METHODS: Consecutive LN+ patients who underwent a resection for PHC in 12 centers were compared with patients who did not undergo resection because of locally advanced disease at exploratory laparotomy in 2 centers. RESULTS: In the resected cohort of 119 patients, the median overall survival (OS) was 19 months and the estimated 1-, 3- and 5-year OS was 69%, 27% and 13%, respectively...
August 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28497252/gallbladder-cancer-presenting-with-jaundice-uniformly-fatal-or-still-potentially-curable
#18
Thuy B Tran, Jeffrey A Norton, Cecilia G Ethun, Timothy M Pawlik, Stefan Buettner, Carl Schmidt, Eliza W Beal, William G Hawkins, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Kamran Idrees, Chelsea A Isom, Ioannis Hatzaras, Rivfka Shenoy, Shishir K Maithel, George A Poultsides
BACKGROUND: Jaundice as a presenting symptom of gallbladder cancer has traditionally been considered to be a sign of advanced disease, inoperability, and poor outcome. However, recent studies have demonstrated that a small subset of these patients can undergo resection with curative intent. METHODS: Patients with gallbladder cancer managed surgically from 2000 to 2014 in 10 US academic institutions were stratified based on the presence of jaundice at presentation (defined as bilirubin ≥4 mg/ml or requiring preoperative biliary drainage)...
August 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28230242/routine-port-site-excision-in-incidentally-discovered-gallbladder-cancer-is-not-associated-with-improved-survival-a-multi-institution-analysis-from-the-us-extrahepatic-biliary-malignancy-consortium
#19
MULTICENTER STUDY
Cecilia G Ethun, Lauren M Postlewait, Nina Le, Timothy M Pawlik, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Kenneth Cardona, Shishir K Maithel
BACKGROUND: Current data on the utility of port-site excision (PSE) during re-resection for incidentally discovered gallbladder cancer (IGBC) in the US are conflicting and limited to single-institution series. METHODS: All patients with IGBC who underwent curative re-resection at 10 institutions from 2000 to 2015 were included. Patients with and without PSE were compared. Primary outcome was overall survival (OS). RESULTS: Of 449 pts with GBC, 266 were incidentally discovered, of which 193(73%) underwent curative re-resection and had port-site data; 47 pts(24%) underwent PSE, 146(76%) did not...
June 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28017812/distal-cholangiocarcinoma-and-pancreas-adenocarcinoma-are-they-really-the-same-disease-a-13-institution-study-from-the-us-extrahepatic-biliary-malignancy-consortium-and-the-central-pancreas-consortium
#20
MULTICENTER STUDY
Cecilia G Ethun, Alexandra G Lopez-Aguiar, Timothy M Pawlik, George Poultsides, Kamran Idrees, Ryan C Fields, Sharon M Weber, Clifford Cho, Robert C Martin, Charles R Scoggins, Perry Shen, Carl Schmidt, Ioannis Hatzaras, David Bentrem, Syed Ahmad, Daniel Abbott, Hong Jin Kim, Nipun Merchant, Charles A Staley, David A Kooby, Shishir K Maithel
BACKGROUND: Distal cholangiocarcinoma (DC) and pancreatic ductal adenocarcinoma (PDAC) are often managed as 1 entity, yet direct comparisons are lacking. Our aim was to use 2 large multi-institutional databases to assess treatment, pathologic, and survival differences between these diseases. STUDY DESIGN: This study included patients with DC and PDAC who underwent curative-intent pancreaticoduodenectomy from 2000 to 2015 at 13 institutions comprising the US Extrahepatic Biliary Malignancy and Central Pancreas Consortiums...
April 2017: Journal of the American College of Surgeons
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