keyword
MENU ▼
Read by QxMD icon Read
search

fat tissue

keyword
https://www.readbyqxmd.com/read/28351093/angptl8-betatrophin-is-expressed-in-visceral-adipose-tissue-and-relates-to-human-hepatic-steatosis-in-two-independent-clinical-collectives
#1
Christian von Loeffelholz, Andreas F H Pfeiffer, Johan F Lock, Steffi Lieske, Stephanie Döcke, Veronica Murahovschi, Jennifer Kriebel, Tonia de Las Heras Gala, Harald Grallert, Natalia Rudovich, Martin Stockmann, Joachim Spranger, Gerhard Jahreis, Stefan R Bornstein, George Lau, Aimin Xu, Jeanette Schulz-Menger, Louisa Exner, Sven Haufe, Jens Jordan, Stefan Engeli, Andreas L Birkenfeld
Angiopoietin-like protein 8 (ANGPTL8)/betatrophin expression in visceral adipose tissue and associations with circulating fatty acid profile have not yet been investigated.Forty subjects were included in a cross-sectional study, 57 in a dietary weight reduction intervention. Circulating Angiopoietin-like protein 8/betatrophin was measured in all subjects. Liver and adipose tissue were sampled and plasma fatty acids and tissue Angiopoietin-like protein 8/betatrophin expression were evaluated in the cross-sectional study...
March 28, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28350665/moderate-intensity-intermittent-external-volume-expansion-optimizes-the-soft-tissue-response-in-a-murine-model
#2
Giorgio Giatsidis, Liying Cheng, Federico Facchin, Anthony Haddad, Jorge Lujan-Hernandez, Luca Lancerotto, Christoph Gunther Nabzdyk, Hajime Matsumine, Dennis P Orgill
BACKGROUND: Intermittent external volume expansion using suction enhances the vascular network of soft tissues, possibly increasing fat graft survival. However, the optimal kinetics of application have not been determined. Based on their previous experience, the authors hypothesized that moderate-intensity intermittent external volume expansion application may further enhance both the angiogenic and adipogenic potential. METHODS: Fifty 12-week-old wild-type mice were assigned to five experimental groups (n = 10 per group) and underwent five different intermittent applications of external volume expansion (i...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28350656/an-update-on-the-anatomy-of-the-forehead-compartments
#3
Sebastian Cotofana, Asima Mian, Jonathan M Sykes, Wolfgang Redka-Swoboda, Andrea Ladinger, Tatjana Pavicic, Thilo L Schenck, Fahd Benslimane, Fabio Ingallina, Alexander Schlattau
BACKGROUND: The forehead is one of the most frequent locations for neuromodulator and soft tissue filler applications; however, the underlying anatomy is still poorly understood. Thus far, the presence of deep forehead compartments has not been confirmed. METHODS: Twenty Caucasian cephalic specimens, 15 fresh frozen (six female and nine male) and five with formalin-phenol embalmment (three female and two male) were investigated using contrast-enhanced computed tomographic scans, dye injections, and anatomical dissections...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28346857/the-influence-of-epicardial-fat-and-nonalcoholic-fatty-liver-disease-on-heart-rate-recovery-in-metabolic-syndrome
#4
Kyoung Im Cho, Eun Ah Jo, Sang Hoon Cho, Bo Hyun Kim
BACKGROUND: Epicardial adipose tissues reflecting visceral fat accumulations of the heart are associated with metabolic syndrome (MetS) and can be a predictor of other cardiometabolic diseases. It can adversely influence autonomic nervous system (ANS) of heart. Heart rate recovery (HRR) is an easy method for measuring ANS dysfunction. The purpose of this study was to determine whether epicardial fat thickness (EFT) and nonalcoholic fatty liver disease (NAFLD) are related to HRR in patients with MetS...
March 27, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28346854/breast-cancer-related-lymphedema-differentiating-fat-from-fluid-using-magnetic-resonance-imaging-segmentation
#5
Yuka Sen, Yi Qian, Louise Koelmeyer, Robert Borotkanics, Robyn Ricketts, Helen Mackie, Thomas C Lam, Kevin Ho Shon, Hiroo Suami, John Boyages
BACKGROUND: Lymphedema is an iatrogenic complication after breast cancer treatment in which lymph fluid in the affected limb progresses to fat deposition and fibrosis that are amenable to liposuction treatment. Magnetic resonance imaging (MRI) for lymphedema can differentiate fat tissue from fluid, but estimating relative volumes remains problematic. METHODS AND RESULTS: Patients underwent routine bilateral arm MRI both before and after liposuction for advanced lymphedema...
March 27, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28346409/the-metabolic-er-stress-sensor-ire1%C3%AE-suppresses-alternative-activation-of-macrophages-and-impairs-energy-expenditure-in-obesity
#6
Bo Shan, Xiaoxia Wang, Ying Wu, Chi Xu, Zhixiong Xia, Jianli Dai, Mengle Shao, Feng Zhao, Shengqi He, Liu Yang, Mingliang Zhang, Fajun Nan, Jia Li, Jianmiao Liu, Jianfeng Liu, Weiping Jia, Yifu Qiu, Baoliang Song, Jing-Dong J Han, Liangyou Rui, Sheng-Zhong Duan, Yong Liu
Obesity is associated with metabolic inflammation and endoplasmic reticulum (ER) stress, both of which promote metabolic disease progression. Adipose tissue macrophages (ATMs) are key players orchestrating metabolic inflammation, and ER stress enhances macrophage activation. However, whether ER stress pathways underlie ATM regulation of energy homeostasis remains unclear. Here, we identified inositol-requiring enzyme 1α (IRE1α) as a critical switch governing M1-M2 macrophage polarization and energy balance...
March 27, 2017: Nature Immunology
https://www.readbyqxmd.com/read/28346287/the-impact-of-laparoscopic-assisted-colorectal-surgery-using-3-dimensional-reconstruction-for-highly-obese-patients-with-colorectal-cancer
#7
Ryoichi Miyamoto, Sosuke Tadano, Naoki Sano, Satoshi Inagawa, Masayoshi Yamamoto
OBJECTIVES: During laparoscopic-assisted colorectal surgery (LACS), precise recognition of the anatomic variations and relationships among tumor and vessels is required. However, in highly obese patients, it is more difficult to grasp the surgical anatomy due to the presence of dense mesenteric fat tissue. We utilized a 3-dimensional (3D) reconstructed image for preoperative simulation and intraoperative navigation for LACS. In this study, we examined the correlation between patient obesity and 3D-simulated perioperative outcomes...
March 24, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28345131/effect-of-botulinum-toxin-on-inducibility-and-maintenance-of-atrial-fibrillation-in-ovine-myocardial-tissue
#8
Alireza Nazeri, Anand V Ganapathy, Ali Massumi, Mehran Massumi, Egemen Tuzun, Raymond Stainback, Ana-Maria Segura, Macarthur A Elayda, Mehdi Razavi
BACKGROUND: Aberrant vagal stimulation may promote the generation and propagation of atrial fibrillation (AF). Researchers have suggested that botulinum toxin (BTX), a neurotoxin that decreases neural vagal stimulation, may decrease the incidence of postoperative AF. The exact electrophysiologic mechanism underlying the observations and histopathologic alterations associated with BTX are unclear. OBJECTIVE: To investigate the electrophysiologic, functional, and histopathologic effects of BTX on fibrillation induction in ovine atria...
March 27, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28344760/severe-pulmonary-hypertension-in-aging-female-apolipoprotein-e-deficient-mice-is-rescued-by-estrogen-replacement-therapy
#9
Soban Umar, Rod Partow-Navid, Gregoire Ruffenach, Andrea Iorga, Shayan Moazeni, Mansoureh Eghbali
BACKGROUND: Apolipoprotein E (ApoE) is a multifunctional protein, and its deficiency leads to the development of atherosclerosis in mice. Patients with pulmonary hypertension (PH) have reduced expression of ApoE in lung tissue. ApoE is known to inhibit endothelial and smooth muscle cell proliferation and has anti-inflammatory and anti-platelet aggregation properties. Young ApoE-deficient mice have been shown to develop PH on high fat diet. The combined role of female sex and aging in the development of PH has not been investigated before...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28344633/the-function-of-myostatin-in-the-regulation-of-fat-mass-in-mammals
#10
REVIEW
Bing Deng, Feng Zhang, Jianghui Wen, Shengqiang Ye, Lixia Wang, Yu Yang, Ping Gong, Siwen Jiang
Myostatin (MSTN), also referred to as growth and differentiation factor-8, is a protein secreted in muscle tissues. Researchers believe that its primary function is in negatively regulating muscle because a mutation in its coding region can lead to the famous double muscle trait in cattle. Muscle and adipose tissue develop from the same mesenchymal stem cells, and researchers have found that MSTN is expressed in fat tissues and plays a key role in adipogenesis. Interestingly, MSTN can exert a dual function, either inhibiting or promoting adipogenesis, according to the situation...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28344558/role-of-autonomic-nervous-system-and-orexinergic-system-on-adipose-tissue
#11
REVIEW
Giovanni Messina, Anna Valenzano, Fiorenzo Moscatelli, Monica Salerno, Antonio Lonigro, Teresa Esposito, Vincenzo Monda, Gaetano Corso, Antonietta Messina, Andrea Viggiano, Antonio I Triggiani, Sergio Chieffi, Giuseppe Guglielmi, Marcellino Monda, Giuseppe Cibelli
Adipose tissue, defined as white adipose tissue (WAT) and brown adipose tissue (BAT), is a biological caloric reservoir; in response to over-nutrition it expands and, in response to energy deficit, it releases lipids. The WAT primarily stores energy as triglycerides, whereas BAT dissipates chemical energy as heat. In mammals, the BAT is a key site for heat production and an attractive target to promote weight loss. The autonomic nervous system (ANS) exerts a direct control at the cellular and molecular levels in adiposity...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28344052/keeping-fat-on-time-circadian-control-of-adipose-tissue
#12
REVIEW
Stine Ninel Hansen, Julia Peics, Zachary Gerhart-Hines
Circadian clocks harmonize processes ranging from intracellular biochemistry to whole-body physiology in accordance with the Earth's 24 hour rotation. These intrinsic oscillators are based on an interlocked transcriptional-translational feedback loop comprised from a set of core clock factors. In addition to maintaining rhythmicity in nearly every cell of the body, these clock factors also mediate tissue specific metabolic functions. In this review, we will explore how the molecular clock shapes the unique features of different adipose depots...
March 23, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28344042/exercise-differentially-affects-metabolic-functions-and-white-adipose-tissue-in-female-letrozole-and-dihydrotestosterone-induced-mouse-models-of-polycystic-ovary-syndrome
#13
Rodrigo R Marcondes, Manuel Maliqueo, Romina Fornes, Anna Benrick, Min Hu, Niklas Ivarsson, Mattias Carlström, Samuel W Cushman, Karin G Stenkula, Gustavo A R Maciel, Elisabet Stener-Victorin
Here we hypothesized that exercise in dihydrotestosterone (DHT) or letrozole (LET)-induced polycystic ovary syndrome mouse models improves impaired insulin and glucose metabolism, adipose tissue morphology, and expression of genes related to adipogenesis, lipid metabolism, Notch pathway and browning in inguinal and mesenteric fat. DHT-exposed mice had increased body weight, increased number of large mesenteric adipocytes. LET-exposed mice displayed increased body weight and fat mass, decreased insulin sensitivity, increased frequency of small adipocytes and increased expression of genes related to lipolysis in mesenteric fat...
March 24, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28343799/characterization-of-deficits-across-the-spectrum-of-motor-abilities-in-dialysis-patients-and-the-impact-of-sarcopenic-overweight-and-obesity
#14
Maja Bučar Pajek, Jernej Pajek
BACKGROUND & AIMS: Physical performance deficits in kidney failure predict mortality and quality of life. We aimed to quantify deficits in multiple motor abilities, investigate associations of lean and fat tissue content with test results and analyzed performance of sarcopenic individuals with adipose tissue excess. METHODS: Ninety hemodialysis patients and 140 healthy controls performed 6-minute walk test, gait speed measurement, sit-to-stand and time up and go tests, upper extremity handgrip and tapping tests, Stork balance and forward bend flexibility tests...
March 16, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28343695/treatment-with-milk-fat-globule-epidermal-growth-factor-factor-8-mfg-e8-reduces-inflammation-and-lung-injury-in-neonatal-sepsis
#15
Laura W Hansen, Weng Lang Yang, Alexandra C Bolognese, Asha Jacob, Tracy Chen, Jose M Prince, Jeffrey M Nicastro, Gene F Coppa, Ping Wang
BACKGROUND: Sepsis remains one of the leading causes of infant death worldwide. It is characterized by uncontrolled inflammatory responses due to proven bacterial infection. Despite improvement in supportive care and the availability of effective antibiotics, no specific therapy targeting the dysregulated inflammatory response is available for neonatal sepsis. Milk fat globule epidermal growth factor-factor 8 (MFG-E8) is a secretory glycoprotein abundantly present in human milk. MFG-E8 suppresses the systemic inflammatory responses in adult murine injury models by improving the clearance of dying cells...
March 23, 2017: Surgery
https://www.readbyqxmd.com/read/28343217/contribution-of-hyoid-and-tonsillar-procedures-to-outcome-in-multilevel-surgery-for-obstructive-sleep-apnea-syndrome
#16
Nora Tetter, Kurt Tschopp
BACKGROUND/OBJECTIVE: In multilevel surgery for obstructive sleep apnea (OSA), the contribution of distinct operative steps is still unclear. The aim of the present study is to retrospectively compare different combinations of multilevel surgeries in order to estimate the contribution of hyoid and tonsillar procedures to the outcome. METHODS: A total of 45 patients were selected in a retrospectively matched case-control study from a database of patients who underwent surgery for OSA at our institution: group A (n = 15) had hyoid suspension, tonsillectomy, and radiofrequency-assisted uvulopalatoplasty (RAUP); group B (n = 15) had hyoid pharyngoplasty with resection of the hyoid body and preepiglottic fat tissue, tonsillectomy, and RAUP; and group C (n = 15) had hyoid suspension and RAUP but no tonsillectomy, because the tonsils had already been removed...
March 25, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/28342374/accumulation-of-%C3%AE-hexabromocyclododecane-%C3%AE-hbcdd-in-tissues-of-fast-and-slow-growing-broilers-gallus-domesticus
#17
Catherine Jondreville, Ronan Cariou, Bertrand Méda, Elena Dominguez-Romero, Elsa Omer, Gaud Dervilly-Pinel, Bruno Le Bizec, Angélique Travel, Elisabeth Baéza
The aim of the current study was to describe the fate of ingested α-hexabromocyclododecane (α-HBCDD) in fast-growing (FG) and slow-growing (SG) broilers, through an exposure to a dietary concentration of 50 ng α-HBCDD g(-1) feed during 42 and 84 days, respectively. Depuration parameters were assessed in SG broilers successively exposed during 42 days and depurated during 42 days. At market age, SG broilers had ingested 42% more feed than FG broilers, while their body weight gain per g of feed ingested was 34% lower...
March 22, 2017: Chemosphere
https://www.readbyqxmd.com/read/28342191/exploiting-multicompartment-effects-in-triple-echo-steady-state-t2-mapping-for-fat-fraction-quantification
#18
Dian Liu, Andreas Steingoetter, Jelena Curcic, Sebastian Kozerke
PURPOSE: To investigate and exploit the effect of intravoxel off-resonance compartments in the triple-echo steady-state (TESS) sequence without fat suppression for T2 mapping and to leverage the results for fat fraction quantification. METHODS: In multicompartment tissue, where at least one compartment is excited off-resonance, the total signal exhibits periodic modulations as a function of echo time (TE). Simulated multicompartment TESS signals were synthesized at various TEs...
March 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28342156/diet-change-after-sleeve-gastrectomy-is-more-effective-for-weight-loss-than-surgery-only
#19
Joana Rossell, Marta González, Núria Mestres, Eva Pardina, David Ricart-Jané, Julia Peinado-Onsurbe, Juan Antonio Baena-Fustegueras
BACKGROUND: Bariatric surgery with or without diet change has become one of the most effective treatments for obesity. The objective of this study was to observe the effects of vertical sleeve gastrectomy (VSG) and diet change in Sprague-Dawley rats on both body and tissue weights. METHODS: Eighteen rats were fed with a standard chow diet (SCD) (C group), and 36 rats were fed with a high-fat diet (HFD) (diet-induced obesity (DIO) group). After 8 weeks, the animals underwent VSG, sham surgery or no surgery (NS)...
March 24, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28341872/childhood-adversity-associated-with-white-matter-alteration-in-the-corpus-callosum-corona-radiata-and-uncinate-fasciculus-of-psychiatrically-healthy-adults
#20
Simon McCarthy-Jones, Lena K L Oestreich, Amanda E Lyall, Zora Kikinis, Dominick T Newell, Peter Savadjiev, Martha E Shenton, Marek Kubicki, Ofer Pasternak, Thomas J Whitford
Diffusion tensor imaging studies report childhood adversity (CA) is associated with reduced fractional anisotropy (FA) in multiple white matter tracts in adults. Reduced FA may result from changes in tissue, suggesting myelin/axonal damage, and/or from increased levels of extracellular free-water, suggesting atrophy or neuroinflammation. Free-water imaging can separately identify FA in tissue (FAT) and the fractional volume of free-water (FW). We tested whether CA was associated with altered FA, FAT, and FW in seven white matter regions of interest (ROI), in which FA changes had been previously linked to CA (corona radiata, corpus callosum, fornix, cingulum bundle: hippocampal projection, inferior fronto-occipital fasciculus, superior longitudinal fasciculus, uncinate fasciculus)...
March 25, 2017: Brain Imaging and Behavior
keyword
keyword
107911
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"