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https://www.readbyqxmd.com/read/29684768/aberrant-parasympathetic-reactivity-to-acute-psychosocial-stress-in-male-patients-with-schizophrenia-spectrum-disorders
#1
Elizabeth H Andersen, Gregory F Lewis, Aysenil Belger
Autonomic dysfunction represents a core domain of the pathophysiology of schizophrenia spectrum disorders (SCZ), with aberrant physiologic arousal underlying maladaptive social and cognitive behaviors. Antagonistic parasympathetic and sympathetic systems support autonomic flexibility to appropriately regulate arousal and respond to environmental challenges, which can be modeled using physiologic measures. SCZ patients consistently show heightened basal stress, however, their parasympathetic reactivity to an acute psychosocial stressor is poorly understood...
April 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29684162/lifemap-towards-the-development-of-a-new-technology-in-sudden-cardiac-death-risk-stratification-for-clinical-use
#2
Ghulam André Ng, Amar Mistry, Xin Li, Fernando S Schlindwein, William B Nicolson
Sudden cardiac death (SCD) is a major cause of mortality presenting a significant unmet clinical need. Patients at risk of SCD are implanted with implantable cardioverter-defibrillators (ICDs) according to international guidelines based on clinical trial evidence. Implantable cardioverter-defibrillators are not inexpensive and not without problem in terms of inappropriate shocks and infection risk. Also, only a minority of patients implanted with the ICD ever use the device during its battery lifetime highlighting the fact that methods used for SCD risk stratification are inadequate...
April 19, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29683838/relationship-between-ventricular-arrhythmias-conduction-disorders-and-myocardial-fibrosis-in-patients-with-systemic-sclerosis-the-role-of-cardiac-magnetic-resonance
#3
Giacomo De Luca, Corrado Campochiaro, Giulio Cavalli, Lorenzo Dagna
No abstract text is available yet for this article.
April 16, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29682848/the-stop-bang-questionnaire-shows-an-insufficient-specificity-for-detecting-obstructive-sleep-apnea-in-patients-with-atrial-fibrillation
#4
Asmaa M Abumuamar, Paul Dorian, David Newman, Colin M Shapiro
Obstructive sleep apnea (OSA) is a sleep disorder associated with significant cardiovascular comorbidities, including cardiac arrhythmia. The STOP-BANG questionnaire is an eight-item self-report questionnaire designed to screen patients for OSA and was validated in preoperative surgical patients. The STOP items are snoring, daytime tiredness, observed apneas and high blood pressure. The BANG items are body mass index >35 kg/m2 , age >50 years, neck circumference >40 cm and male gender. We aimed to determine the screening properties of the STOP-BANG questionnaire in patients with arrhythmia...
April 22, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29680999/current-state-of-left-atrial-appendage-closure
#5
REVIEW
Ricardo Kosturakis, Matthew J Price
PURPOSE OF REVIEW: Atrial fibrillation (AF), the most common sustained arrhythmia, is a major cause of stroke and systemic embolism, and is increasing in prevalence. Device closure of the left atrial appendage (LAA) represents a non-pharmacologic approach to stroke prevention in AF patients. This review presents the rationale for LAA closure (LAAC), describes current transcatheter approaches to LAAC, and summarizes the current evidence for LAAC for stroke prevention, highlighting the main randomized trials and the most recent data available...
April 21, 2018: Current Cardiology Reports
https://www.readbyqxmd.com/read/29680825/estimated-cardiac-risk-associated-with-macrolides-and-fluoroquinolones-decreases-substantially-when-adjusting-for-patient-characteristics-and-comorbidities
#6
Linnea A Polgreen, Benjamin N Riedle, Joseph E Cavanaugh, Saket Girotra, Barry London, Mary C Schroeder, Philip M Polgreen
BACKGROUND: Some studies have found that antimicrobials, especially macrolides, increase the risk of cardiovascular death. We investigated potential cardiac-related events associated with antimicrobial use in a population of patients with acute myocardial infarction. METHODS AND RESULTS: For 185 010 Medicare beneficiaries, we recorded prescriptions for azithromycin, clarithromycin, levofloxacin, moxifloxacin, doxycycline, and amoxicillin-clavulanate. In the following week, we recorded death, acute myocardial infarction, atrial fibrillation or atrial flutter, a non-atrial fibrillation/atrial flutter arrhythmia, or ventricular arrhythmia...
April 21, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29680416/electrocardiographic-variables-in-children-with-syndromic-craniosynostosis-and-primary-snoring-to-mild-obstructive-sleep-apnea-significance-of-identifying-respiratory-arrhythmia-during-sleep
#7
Ellaha Kakar, Linda J A Corel, Robert C Tasker, Robbin de Goederen, Eppo B Wolvius, Irene M J Mathijssen, Koen F M Joosten
BACKGROUND: In the spectrum of children with symptomatic sleep disordered breathing (SDB), some individuals - such as those with upper airway resistance syndrome (UARS) - do not have abnormalities on polysomnography (PSG). In this study we have assessed whether assessment of respiratory arrhythmia (RA) and heart rate variability (HRV) analysis helps in management of children with syndromic craniosynostosis and none-to-mild obstructive sleep apnea (OSA). METHODS: Prospective cohort study in children aged 1-18 years old with syndromic craniosynostosis...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29680382/phenotypic-description-of-cardiac-findings-in-a-population-of-dogue-de-bordeaux-with-an-emphasis-on-atrial-fibrillation
#8
G McAulay, K Borgeat, J Sargent, P Mõtsküla, J Neves, J Dukes-McEwan, V Luis Fuentes
The aim of this study was to describe the clinical phenotype of Dogue de Bordeaux (DdB) referred for cardiac investigation, with particular reference to the prevalence of atrial fibrillation and associated features. Review of canine medical records of two United Kingdom veterinary referral hospitals identified 64 DdB with available echocardiographic and electrocardiographic (ECG)/Holter data. Atrial fibrillation was documented in 25 (39%) dogs and supraventricular tachycardia was recorded in five (7.8%) dogs...
April 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29679302/association-of-abnormal-serum-potassium-levels-with-arrhythmias-and-cardiovascular-mortality-a-systematic-review-and-meta-analysis-of-observational-studies
#9
REVIEW
Liesa K Hoppe, Dana C Muhlack, Wolfgang Koenig, Prudence R Carr, Hermann Brenner, Ben Schöttker
PURPOSE: To provide the first systematic review and meta-analysis of observational studies on the association of abnormal serum potassium and cardiovascular outcomes. METHODS: Medline and ISI Web of Knowledge were systematically searched from inception until November 24, 2017. Data synthesis of relevant studies was performed using random effects model meta-analyses. RESULTS: Meta-analyses included 310,825 participants from 24 studies. In the older general population, low serum potassium was associated with a 1...
April 20, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29679186/impact-of-an-additional-right-pulmonary-vein-on-second-generation-cryoballoon-ablation-for-atrial-fibrillation-a-propensity-matched-score-study
#10
Ken Takarada, Erwin Ströker, Juan-Pablo Abugattas, Valentina de Regibus, Hugo-Enrique Coutiño, Ian Lusoc, Lucio Capulzini, Juan Sieira, Giacomo Mugnai, Francesca Salghetti, Rajin Choudhury, Saverio Iacopino, Carlo de Asmundis, Pedro Brugada, Gian-Battista Chierchia
PURPOSE: Cryoballoon (CB) technology in the context of anatomical pulmonary vein (PV) variants might hypothetically hamper successful PV isolation (PVI). Our aim was to assess the impact of a right middle PV (RMPV) in the setting of second-generation cryoballoon (CB advance-CB-A), on procedural parameters and on mid-term follow-up. METHODS: Consecutive patients with AF presenting RMPV (RMPV+) at the pre-procedural computed tomography who underwent PVI by CB-A were enrolled...
April 21, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29678964/technology-enabled-examinations-of-cardiac-rhythm-optic-nerve-oral-health-tympanic-membrane-gait-and-coordination-evaluated-jointly-with-routine-health-screenings-an-observational-study-at-the-2015-kumbh-mela-in-india
#11
Pratik Shah, Gregory Yauney, Otkrist Gupta, Vincent Patalano Ii, Mrinal Mohit, Rikin Merchant, S V Subramanian
OBJECTIVES: Technology-enabled non-invasive diagnostic screening (TES) using smartphones and other point-of-care medical devices was evaluated in conjunction with conventional routine health screenings for the primary care screening of patients. DESIGN: Dental conditions, cardiac ECG arrhythmias, tympanic membrane disorders, blood oxygenation levels, optic nerve disorders and neurological fitness were evaluated using FDA-approved advanced smartphone powered technologies...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678779/experience-with-the-wearable-cardioverter-defibrillator-in-older-patients-results-from-the-prospective-registry-of-patients-using-the-wearable-cardioverter-defibrillator-wearit-ii-registry
#12
Usama A Daimee, Katherine Vermilye, Arthur J Moss, Ilan Goldenberg, Helmut U Klein, Scott McNitt, Wojciech Zareba, Valentina Kutyifa
BACKGROUND: Use of the wearable cardioverter-defibrillator (WCD) in older patients has not been described previously. OBJECTIVES: To assess WCD wear time, risk of arrhythmia events during WCD use, and implantable cardioverter-defibrillator (ICD) implantation rates following end of WCD use in patients with age ≥65 vs. <65 years. METHODS: We stratified 1,732 patients with ischemic and non-ischemic cardiomyopathies from the WEARIT-II registry into two sub-groups by age: ≥65 and <65 years...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29678777/a-10-year-review-of-sudden-death-during-sporting-activities
#13
Mark Dennis, Alexander Elder, Christopher Semsarian, John Orchard, Isabel Brouwer, Rajesh Puranik
BACKGROUND: Sudden death during sport is a rare but devastating event. Previous research has mostly focused on sudden deaths in young competitive athletes. OBJECTIVE: To characterise the demographics and aetiology of sudden cardiac death (SCD) during sport in Australia. METHODS: All autopsies conducted at our forensic medicine facility between the years 2006-2015 (inclusive) were reviewed. Sporting related deaths amongst those 7-65 years of age were identified...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29678624/autonomic-cardiovascular-control-and-cardiac-arrhythmia-in-two-pregnant-women-with-hypertrophic-cardiomyopathy-insights-from-icd-monitoring
#14
Pietro Francia, Carmen Adduci, Beatrice Musumeci, Lorenzo Semprini, Francesca Palano, Luigi Zezza, Massimo Volpe, Camillo Autore
In women with hypertrophic cardiomyopathy (HCM), pregnancy prompts major changes in hemodynamic and cardiac autonomic function that may precipitate heart failure (HF) or increase the risk of cardiac arrhythmia. We report the clinical follow-up of two patients with non-obstructive HCM implanted with a cardioverter defibrillator (ICD) allowing for continuous analysis of heart rate (HR), heart rate variability (HRV) and cardiac arrhythmia throughout the entire course of pregnancy. Both patients experienced increased HR and decreased HRV from the early stages of pregnancy, which persisted until delivery...
April 17, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29678336/stress-myocardial-blood-flow-heterogeneity-is-a-positron-emission-tomography-biomarker-of-ventricular-arrhythmias-in-patients-with-hypertrophic-cardiomyopathy
#15
Dai-Yin Lu, Hulya Yalçin, Fatih Yalçin, Min Zhao, Sanjay Sivalokanathan, Ines Valenta, Abdel Tahari, Martin G Pomper, Theodore P Abraham, Thomas H Schindler, M Roselle Abraham
Patients with hypertrophic cardiomyopathy (HC) are at increased risk of sudden cardiac death. Abnormalities in myocardial blood flow (MBF) detected by positron emission tomography (PET) are common in HC, but a PET marker that identifies patients at risk of sudden cardiac death is lacking. We hypothesized that disparities in regional myocardial perfusion detected by PET would identify patients with HC at risk of ventricular arrhythmias. To test this hypothesis, we quantified global and regional MBFs by 13 NH3 -PET at rest and at stress, and developed a heterogeneity index to assess MBF heterogeneity in 133 symptomatic patients with HC...
February 6, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29678335/arrhythmic-risk-stratification-in-patients-with-idiopathic-dilated-cardiomyopathy
#16
Davide Stolfo, Nicole Ceschia, Massimo Zecchin, Antonio De Luca, Marco Gobbo, Giulia Barbati, Marta Gigli, Marco Masè, Bruno Pinamonti, Alberto Pivetta, Marco Merlo, Gianfranco Sinagra
Arrhythmic risk stratification in idiopathic dilated cardiomyopathy (IDC) remains a major concern. As the ventricles remodel in time, risk factors for arrhythmic death may change. A cohort of 710 patients with idiopathic dilated cardiomyopathy, without previous ventricular arrhythmias, was retrospectively studied to understand how risks vary in time. The primary end point was a composite of sudden cardiac death, ventricular fibrillation, sustained ventricular tachycardia, and appropriate implantable cardioverter-defibrillator interventions...
March 14, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29677053/safety-profile-of-baroreflex-activation-therapy-neo-in-patients-with-resistant-hypertension
#17
Manuel Wallbach, Enrico Böhning, Luca-Yves Lehnig, Charlotte Schroer, Gerhard Anton Müller, Rolf Wachter, Stephan Lüders, Dieter Zenker, Michael Johann Koziolek
OBJECTIVE: Unlike safety data of baroreflex activation therapy device (Rheos), only few data of the currently used second device (Barostim neo) are available and little is reported about common side effects. METHODS: We prospectively analyzed patients with resistant hypertension treated with Barostim neo. A standardized interview regarding side effects of the therapy was performed in routine follow-up visits after device implantation in 42 patients to determine adverse events staged into three degrees...
April 19, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29675598/design-of-a-biorthogonal-wavelet-transform-based-r-peak-detection-and-data-compression-scheme-for-implantable-cardiac-pacemaker-systems
#18
Ashish Kumar, Manjeet Kumar, Rama Komaragiri
Bradycardia can be modulated using the cardiac pacemaker, an implantable medical device which sets and balances the patient's cardiac health. The device has been widely used to detect and monitor the patient's heart rate. The data collected hence has the highest authenticity assurance and is convenient for further electric stimulation. In the pacemaker, ECG detector is one of the most important element. The device is available in its new digital form, which is more efficient and accurate in performance with the added advantage of economical power consumption platform...
April 19, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29675595/involvement-of-cytosolic-and-mitochondrial-iron-in-iron-overload-cardiomyopathy-an-update
#19
REVIEW
Richard Gordan, Suwakon Wongjaikam, Judith K Gwathmey, Nipon Chattipakorn, Siriporn C Chattipakorn, Lai-Hua Xie
Iron overload cardiomyopathy (IOC) is a major cause of death in patients with diseases associated with chronic anemia such as thalassemia or sickle cell disease after chronic blood transfusions. Associated with iron overload conditions, there is excess free iron that enters cardiomyocytes through both L- and T-type calcium channels thereby resulting in increased reactive oxygen species being generated via Haber-Weiss and Fenton reactions. It is thought that an increase in reactive oxygen species contributes to high morbidity and mortality rates...
April 19, 2018: Heart Failure Reviews
https://www.readbyqxmd.com/read/29675061/comorbidities-with-non-small-cell-lung-cancer-is-there-an-interdisciplinary-consensus-needed-to-qualify-patients-for-surgical-treatment
#20
Marta Lembicz, Piotr Gabryel, Beata Brajer-Luftmann, Wojciech Dyszkiewicz, Halina Batura-Gabryel
INTRODUCTION: Radical surgical treatment is the preferred action for patients with early-stage non-small cell lung cancer (NSCLC). Qualification for surgical treatment should consider a risk associated with the effect of comorbidities on the general condition of the patient. The aim of this article was an attempt to identify the risk factors for postoperative complications in patients treated for NSCLC, with a special focus on the coexisting diseases. METHODS: A total of 400 patients with NSCLC were included in this retrospective study...
April 2018: Annals of Thoracic Medicine
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