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https://www.readbyqxmd.com/read/28231545/aqueous-extract-of-cortex-dictamni-protects-h9c2-cardiomyocytes-from-hypoxia-reoxygenation-induced-oxidative-stress-and-apoptosis-by-pi3k-akt-signaling-pathway
#1
Lin Li, Yunfeng Zhou, Yanlin Li, Lili Wang, Lan Sun, Lidong Zhou, Hiderori Arai, Yun Qi, Yang Xu
Ischemia-reperfusion injury is the major manifestation of ischemic heart disease, which facilitates cardiac arrhythmias, heart failure and death. Oxidative stress and apoptosis have been involved in the pathogenesis of myocardial ischemia-reperfusion injury. Modern pharmacological studies have indicated that the extracts and active compounds of Cortex Dictamni exhibit antioxidative and cardiovascular protective activities. This study was designed to investigate the protective effect of aqueous extract of Cortex Dictamni (CDAE) on regulating hypoxia/reoxygenation (H/R)-induced cardiomyocytes oxidative stress and apoptosis...
February 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28231325/cardiovascular-exercise-and-burden-of-arrhythmia-in-patients-with-atrial-fibrillation-a-randomized-controlled-trial
#2
Ane Katrine Skielboe, Thomas Quaade Bandholm, Stine Hakmann, Malene Mourier, Thomas Kallemose, Ulrik Dixen
BACKGROUND: Physical activity at moderate-high intensity is recommended to prevent lifestyle diseases. Patients with atrial fibrillation are at risk of a sedentary lifestyle due to fear of exercise-induced episodes of atrial fibrillation. The burden of arrhythmia can be reduced by physical exercise. The effect of exercise intensity on burden of atrial fibrillation needs to be studied further. METHODS AND RESULTS: In a 12-week randomized controlled trial, 76 patients with paroxysmal/persistent atrial fibrillation were allocated to perform exercise at either low intensity or high intensity (50% and 80% of maximal perceived exertion, respectively)...
2017: PloS One
https://www.readbyqxmd.com/read/28230036/single-lumen-tracheal-ventilation-for-minimally-invasive-esophagectomy-in-patients-with-esophageal-cancer
#3
Yu Bai, Yi Zhou, Xi Hua Lu
OBJECTIVE: The aim of this study was to observe the efficacy and safety of single-lumen tracheal ventilation for esophageal cancer surgery. METHODS: Thirty-eight patients with esophageal carcinoma who prepared for minimally invasive esophagectomy were included in this study. All of the included 38 patients were received single-lumen tracheal ventilation. The arterial blood gas index was monitored through the operation procedure and recorded at four-time points: before induction (T0), at the end of chest operation (T1), at the end of the abdominal operation (T2), and 30 min after extubation (T3)...
December 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28229981/postprocedural-outcomes-and-risk-factors-for-arrhythmias-following-transcatheter-closure-of-congenital-perimembranous-ventricular-septal-defect-a-single-center-retrospective-study
#4
Li-Jian Zhao, Bo Han, Jian-Jun Zhang, Ying-Chun Yi, Dian-Dong Jiang, Jian-Li Lyu
BACKGROUND: Currently, transcatheter closure of perimembranous ventricular septal defect (pmVSD) is a widely accepted therapeutic modality. However, arrhythmias, especially postprocedural heart blocks, are a concern and outcomes are not very clear. This study explored the outcomes and risk factors of arrhythmias associated with transcatheter device closure of pmVSD. METHODS: A total of 395 patients diagnosed with pmVSD who successfully underwent transcatheter intervention between January 2010 and December 2015 in our center were retrospectively reviewed...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28229201/-sudden-cardiac-death-epidemiology-pathophysiology-and-risk-stratification
#5
B Rudic, E Tülümen, V Liebe, J Kuschyk, I Akin, M Borggrefe
Sudden cardiac death (SCD) remains a major public health burden despite revolutionary progress in the last three decades in the treatment of ventricular tachyarrhythmia with the use of implantable cardioverter defibrillator (ICD) therapy. Survivors of sudden cardiac arrest are at high risk for recurrent tachyarrhythmia events. Early recognition of low left ventricular ejection fractions (≤35%) as a strong predictor of mortality and the causal association between ventricular tachyarrhythmia and SCD has led to a significant development of not only pharmacological antiarrhythmic therapy but also device-based prevention of SCD...
February 22, 2017: Herz
https://www.readbyqxmd.com/read/28229199/-coronary-artery-disease-interventional-and-operative-therapeutic-options-after-cardiac-arrest
#6
M Behnes, K Mashayekhi, M Borggrefe, I Akin
Coronary artery disease (CAD) represents a common structural cause for developing cardiac arrest in older patients, whereas in young adults cardiac arrest is more often caused by cardiomyopathies and cardiac channelopathies. A structural heart disease is known in almost 50% of patients prior to cardiac arrest. The present review outlines current interventional and operative therapeutic options for patients surviving cardiac arrest. The focus is on associations between epidemiological data on the incidence of malignant arrhythmias causing cardiac arrest depending on the presence or absence of CAD...
February 22, 2017: Herz
https://www.readbyqxmd.com/read/28228428/the-effect-of-aggressive-blood-pressure-control-on-the-recurrence-of-atrial-fibrillation-after-catheter-ablation-a-randomized-open-label-clinical-trial-substrate-modification-with-aggressive-blood-pressure-control-smac-af
#7
Ratika Parkash, George A Wells, John L Sapp, Jeffrey S Healey, Jean-Claude Tardif, Isabelle Greiss, Léna Rivard, Jean-Francois Roux, Lorne Gula, Isabelle Nault, Paul G Novak, David H Birnie, Andrew C Ha, Stephen B Wilton, Iqwal Mangat, Christopher J Gray, Martin J Gardner, Anthony S L Tang
Background -Radiofrequency catheter ablation for atrial fibrillation has become an important therapy for AF, however recurrence rates remain high. We proposed to determine whether aggressive blood pressure (BP) lowering prevents recurrent atrial fibrillation (AF) after catheter ablation in patients with AF and a high symptom burden. Methods -We randomly assigned 184 patients with AF and a BP greater than 130/80 mmHg to aggressive BP (target <120/80 mm Hg) or standard BP treatment (target <140/90 mmHg) prior to their scheduled AF catheter ablation...
February 22, 2017: Circulation
https://www.readbyqxmd.com/read/28228335/alterations-in-cardiac-autonomic-control-in-spinal-cord-injury
#8
Fin Biering-Sørensen, Tor Biering-Sørensen, Nan Liu, Lasse Malmqvist, Jill Maria Wecht, Andrei Krassioukov
A spinal cord injury (SCI) interferes with the autonomic nervous system (ANS). The effect on the cardiovascular system will depend on the extent of damage to the spinal/central component of ANS. The cardiac changes are caused by loss of supraspinal sympathetic control and relatively increased parasympathetic cardiac control. Decreases in sympathetic activity result in heart rate and the arterial blood pressure changes, and may cause arrhythmias, in particular bradycardia, with the risk of cardiac arrest in those with cervical or high thoracic injuries...
February 15, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28227934/effect-of-embedding-dimension-on-complexity-measures-in-identifying-arrhythmia
#9
Radhagayathri K Udhayakumar, Chandan Karmakar, Peng Li, Marimuthu Palaniswami, Radhagayathri K Udhayakumar, Chandan Karmakar, Peng Li, Marimuthu Palaniswami, Marimuthu Palaniswami, Radhagayathri K U Udhayakumar, Peng Li, Chandan Karmakar
Entropy measures like Approximate entropy (ApEn) and Sample entropy (SampEn) are well established tools to analyze Heart Rate Variability (HRV) data. Critical parameters involved in these computations namely embedding dimension m and tolerance r are in most cases assumed to be 2 and 0.2*signal SD (standard devaition) respectively. Such assumptions do not work fairly across data sets and thus create misleading results in many cases. Problems with r have been addressed with the advent of newer entropy measures like Permutation entropy (PE), Fuzzy entropy (FuzzyEn) and Distribution entropy (DistEn) that simply eliminate, modify or replace r from calculations...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227775/3d-anatomical-reconstruction-of-human-cardiac-conduction-system-and-simulation-of-bundle-branch-block-after-tavi-procedure
#10
Andrew J Atkinson, Sanjay R Kharche, Michael G Bateman, Paul A Iaizzo, Halina Dobrzynski, Andrew J Atkinson, Sanjay R Kharche, Michael G Bateman, Paul A Iaizzo, Halina Dobrzynski, Andrew J Atkinson, Paul A Iaizzo, Halina Dobrzynski, Sanjay R Kharche, Michael G Bateman
The cardiac conduction system (CCS) is responsible for the initiation and propagation of action potentials through the heart ensuring efficient pumping of blood. Understanding the anatomy of the CCS and its relationship with other major cardiac components is important to help understand arrhythmias and how certain procedures may increase the incidence of arrhythmias developing. We sectioned a whole human heart and performed Masson's trichrome histology in order to identify the components of the CCS. The histology images were used to construct a 3D anatomical model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227714/an-efficient-ecg-baseline-removal-filter-based-on-frequency-response-masking-technique-for-wearable-applications
#11
Boxiao Liu, Guoxing Wang, Yong Lian, Boxiao Liu, Guoxing Wang, Yong Lian, Guoxing Wang, Yong Lian, Boxiao Liu
This paper presents a computationally efficient FIR (finite impulse response) filter for ECG (electrocardiogram) baseline wander removal. The proposed filter is based on frequency-response masking (FRM) technique, which reduces the number of multiplications by 90% compared to the conventional FIR filter. The filter specifications are optimized to obtain the highest SNR (signal-to-noise ratio) while minimizing the number of filter coefficients. The SNR performance of the proposed filter is evaluated using ECG signals from MIT-BIH Arrhythmia Database with added baseline noises from MIT-BIH Noise Stress Test Database...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227713/gpu-based-cloud-system-for-high-performance-arrhythmia-detection-with-parallel-k-nn-algorithm
#12
Tae Joon Jun, Hyun Ji Park, Hyuk Yoo, Young-Hak Kim, Daeyoung Kim, Tae Joon Jun, Hyun Ji Park, Hyuk Yoo, Young-Hak Kim, Daeyoung Kim, Tae Joon Jun, Hyun Ji Park, Young-Hak Kim, Daeyoung Kim, Hyuk Yoo
In this paper, we propose an GPU based Cloud system for high-performance arrhythmia detection. Pan-Tompkins algorithm is used for QRS detection and we optimized beat classification algorithm with K-Nearest Neighbor (K-NN). To support high performance beat classification on the system, we parallelized beat classification algorithm with CUDA to execute the algorithm on virtualized GPU devices on the Cloud system. MIT-BIH Arrhythmia database is used for validation of the algorithm. The system achieved about 93...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227702/socioeconomic-status-age-and-heart-rate-variability-in-a-bangladeshi-community
#13
Nishat E-Sharmin Trisha, Herbert F Jelinek, Mika P Tarvainen, David J Cornforth, Dewan S Alam, Megan Smith, Nishat E-Sharmin Trisha, Herbert F Jelinek, Mika P Tarvainen, David J Cornforth, Dewan S Alam, Megan Smith, Herbert F Jelinek, David J Cornforth, Megan Smith, Nishat E-Sharmin Trisha, Dewan S Alam, Mika P Tarvainen
Socioeconomic status (SES) is a risk factor for cardiovascular disease (CVD) and either low or high heart rate variability (HRV) at rest has been shown to predict cardiovascular morbidity and mortality. The study investigated the extent HRV features can predict SES. Four hundred and twenty eight people were randomly selected from the commercial districts (high SES) and slum areas (low SES) within Dhaka city. Demographic, clinical, and HRV features were recorded. Of the clinical variables age, waist circumference and diastolic blood pressure (p<;0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227569/efficient-compressive-sensing-of-ecg-segments-based-on-machine-learning-for-qrs-based-arrhythmia-detection
#14
Jeevan K Pant, Sridhar Krishnan, Jeevan K Pant, Sridhar Krishnan, Jeevan K Pant, Sridhar Krishnan
A novel method for efficient telemonitoring of arrhythmia based on using QRS complexes is proposed. Two features, namely, sum of absolute differences (SAD) and maximum of absolute differences (MAD) are efficiently computed for each ECG segment in the bio-sensor. The computed features can be transmitted from the bio-sensor using wireless channel, and they can be used in the receiver for determining the absence of QRS complex in the segment. By avoiding computationally expensive signal reconstruction for the ECG segments without QRS complex, it is shown, using simulation results, that computation time can be reduced by approximately 7...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227493/recommendations-for-antiarrhythmic-drugs-based-on-latent-semantic-analysis-with-fc-means-clustering
#15
Juyoung Park, Mingon Kang, Junbeom Hur, Kyungtae Kang, Juyoung Park, Mingon Kang, Junbeom Hur, Kyungtae Kang, Mingon Kang, Junbeom Hur, Juyoung Park, Kyungtae Kang
In this paper, we propose a novel model for the appropriate recommendation of antiarrhythmic drugs by introducing a fusion of a latent semantic analysis and k-means clustering. Our model not only captures the latent factors between the types of arrhythmia and patients but also has the ability to search a group of patients with similar arrhythmias. The performance studies conducted against the MIT-BIH arrhythmia database show that clinicians accepted 66.67% of the drugs recommended from our model with a balanced f-score of 38...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227487/e-health-prototype-system-for-cardiac-telemonitoring
#16
Laura Juliana Vargas Escobar, Sergio Alexander Salinas, Laura Juliana Vargas Escobar, Sergio Alexander Salinas, Sergio Alexander Salinas, Laura Juliana Vargas Escobar
This paper presents the approach of an e-health system for cardiac telemonitoring which uses the development board LinkIt ONE as a monitoring system. Such board was adapted to measure the cardiac pulse, analyze it and determine whether a person is having a cardiac arrhythmia or not. When an arrhythmia appears, the prototype activates an alarm in order to report the patient's condition and its location to a caregiver or a close healthcare center. The data of the cardiac pulse is originated in an e-health sensor platform connected to an Arduino...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227480/detection-of-atrial-fibrillation-with-seismocardiography
#17
Mikko Pankaala, Tero Koivisto, Olli Lahdenoja, Tuomas Kiviniemi, Antti Saraste, Tuija Vasankari, Juhani Airaksinen, Mikko Pankaala, Tero Koivisto, Olli Lahdenoja, Tuomas Kiviniemi, Antti Saraste, Tuija Vasankari, Juhani Airaksinen, Tero Koivisto, Olli Lahdenoja, Tuomas Kiviniemi, Antti Saraste, Tuija Vasankari, Mikko Pankaala, Juhani Airaksinen
In this paper we study the feasibility of seismocardiography (SCG) for the detection of Atrial Fibrillation (AF). In this preclinical study, data acquired from one patient having paroxysmal AF (no other heart diseases) is used to introduce specific changes in SCG signal due to AF. Observed changes and phenomena create a foundation for the development of SCG-based AF detection algorithms. SCG data was recorded from the sternum of an AF patient in dorso-ventral direction while at rest in a supine position using a three-axis high precision MEMS accelerometer simultaneously with a one-lead ECG...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227341/applicability-of-multiresolution-wavelet-analysis-for-qrs-waves-detection
#18
Aleksandr A Fedotov, Anna S Akulova, Sergey A Akulov, Aleksandr A Fedotov, Anna S Akulova, Sergey A Akulov, Aleksandr A Fedotov, Anna S Akulova, Sergey A Akulov
The aim of this study is to create highly effective QRS-detector of electrocardiographic (ECG) signal based on the multiresolution wavelet analysis, set of nonlinear transforms and adaptive thresholding. The efficiency of various QRS-waves detectors for processing model ECG signals contaminated by artificially simulated intensive noise and artifacts was researched. The performance of the proposed method as well as some other well-known algorithms for QRS-waves detection was further verified for clinical ECG recordings from the Physionet MIT-BIH Arrhythmia database...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227260/automated-detection-of-atrial-fibrillation-episode-using-novel-heart-rate-variability-features
#19
Mehrin Gilani, J Mikael Eklund, Masoud Makrehchi, Mehrin Gilani, J Mikael Eklund, Masoud Makrehchi, J Mikael Eklund, Masoud Makrehchi, Mehrin Gilani
Atrial fibrillation (AF) is one of the most common life-threatening arrhythmia affecting around six million adults in the US. Typical detection of AF requires tedious and manual analysis of ECG which can often delay medical intervention. With the advent of wearable devices that can accurately record the time interval between two heartbeats (RR interval), automated and timely detection of AF is now possible. In this paper, we engineer novel heart rate variability features based on linear and non-linear dynamics of RR intervals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227158/interventional-placement-of-thin-coil-shaped-implants-powered-wirelessly-for-monitoring-vital-signals-and-controlling-abnormal-activities-by-electro-stimulation
#20
Hidetoshi Ohta, Masanobu Honda, Makoto Takamiya, Hidetoshi Ohta, Masanobu Honda, Makoto Takamiya, Masanobu Honda, Hidetoshi Ohta, Makoto Takamiya
Various types of implants are being commonly used for monitoring vital signals and controlling the critically ill patient's condition such as arrhythmia, sick sinus syndrome, etc. For implanting these medical devices under the skin, surgery is inevitable. These days many patients are more willing to accept interventional therapies that are less invasive, especially inserting a catheter into a blood vessel or endoscopy through a natural orifice. To be able to use interventional therapy for implanting medical devices, they will need to be small enough to fit them through a catheter or the forceps channel of an endoscope...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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