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Roald Pijpker, Lenneke Vaandrager, Evert Jan Bakker, Maria Koelen
OBJECTIVE: To explore the moderating and mediating role(s) of learning within the relationship between sense of coherence (SOC) and generalized resistance resources. METHOD: Cross-sectional study (N=481), using a self-administered questionnaire, of employees working in the healthcare sector in the Netherlands in 2017. Four residential healthcare settings and one healthcare-related Facebook group were involved. Multiple linear regression models were used to test for moderating and mediating effects of learning...
February 15, 2018: Gaceta Sanitaria
Jasmin Schiefer, Georg J Lair, Christopher Lüthgens, Eva Maria Wild, Peter Steier, Winfried E H Blum
During COP 21 in Paris 2015, several states and organizations agreed on the "4/1000" initiative for food security and climate. This initiative aims to increase world's soil organic carbon (SOC) stocks by 4‰ annually. The influence of soil development status on SOC dynamics is very important but usually not considered in studies. We analyse SOC accumulation under forest, grassland and cropping systems along a soil age gradient (10-17,000years) to show the influence of soil development status on SOC increase...
February 15, 2018: Science of the Total Environment
Jonathan Rychen, Davide Croci, Michel Roethlisberger, Erez Nossek, Matthew Potts, Ivan Radovanovic, Howard Riina, Luigi Mariani, Raphael Guzman, Daniel W Zumofen
OBJECTIVE: Minimally invasive alternatives to the pterional craniotomy include the minipterional and the supraorbital craniotomy (SOC). The latter is performed via either an eyebrow or an eyelid skin incision. The purpose of this systematic review was to analyze the type and the incidence of approach-related complications of these keyhole craniotomies. METHODS: We review pertinent publications retrieved by search in the PubMed/Medline database. Inclusion criteria were all full-text publications, abstracts, and posters in English, up to 2016, reporting clinical results...
February 13, 2018: World Neurosurgery
Bo Wei, Michael Schroeder, Manfred Martin
The surface chemistry and the Cr tolerance ability of oxygen electrodes play a vital role in the performance and long-term stability of solid oxide cells (SOCs). In this paper, the surface cation segregations on the double perovskite oxide PrBaCo2O5+δ (PBCO) and its relationship with Cr deposition are reported. During high temperature annealing in an O2 atmosphere, the elements Ba and Co diffuse out of the lattice and form many BaO and Co3O4 precipitates on the surface, mainly located at grain boundaries. In the presence of volatile Cr species, the observation of BaCrO4 but not CoCr2O4 on a segregated PBCO surface reveals that the Cr deposition preferentially takes place on segregated BaO rather than on Co3O4 precipitates...
February 16, 2018: ACS Applied Materials & Interfaces
H M Beccacece, G San Blas, M E Drewniak, M J Barrionuevo, E R Krauczuk, A E Chalup, A I Zapata
A taxonomical rearrangement of "Aemilia" pagana species-group is proposed: Leucanopsis pagana (Schaus in Proc Zool Soc London 1894:225-243, 1894) comb. nov. and L. ninae (Orfila in Rev Soc Entomol Argent 21:67-70, 1959) comb. nov. A new endemic species from Pampa de Achala, Córdoba, Argentina, closer to both species, is described: Leucanopsis navarroi sp. nov. These three species can be recognized because the color pattern is the darkest among species of Leucanopsis. Characteristics of male genitalia suggest the nomenclatural rearrangement proposed...
February 15, 2018: Neotropical Entomology
Li Xu, Guirui Yu, Nianpeng He, Qiufeng Wang, Yang Gao, Ding Wen, Shenggong Li, Shuli Niu, Jianping Ge
It is important to accurately estimate terrestrial ecosystem carbon (C) storage. However, the spatial patterns of C storage and the driving factors remain unclear, owing to lack of data. Here, we collected data from literature published between 2004 and 2014 on C storage in China's terrestrial ecosystems, to explore variation in C storage across different ecosystems and evaluate factors that influence them. We estimated that total C storage was 99.15 ± 8.71 PgC, with 14.60 ± 3.24 PgC in vegetation C (Veg-C) and 84...
February 12, 2018: Scientific Reports
Yiying Yang, Yanhong Liu, Pingli Lv, Rongxiu Zhu, Chengbu Liu, Dongju Zhang
This work aims at understanding the mechanism and regioselectivity in ligand-controlled gold-catalyzed divergent intramolecular hydroarylation of alkynes reported by Jiang et al. [J. Am. Chem. Soc. 2016, 138, 5218-5221]. Focusing on a representative alkyne, N-propargyl-N-tosyl aniline, we conducted a detailed computational study on the ortho- and para-position hydroarylation of the alkyne catalyzed by gold(I) catalysts with different ligands. Both the ortho- and para-position hydroarylation reactions are found to follow a similar three-stage mechanism: electrophilic cyclization, proton loss, and protiodeauration...
February 12, 2018: Journal of Organic Chemistry
Yu Liu, Sten H Vermund, Yuhua Ruan, Hongjie Liu, K Rivet Amico, Jane M Simoni, Bryan E Shepherd, Yiming Shao, Han-Zhu Qian
INTRODUCTION: Reducing high-risk behaviours (i.e. multiple partnership, condomless anal/vaginal sex, alcohol use before sex, illicit drug use) after HIV diagnosis is critical for curtailing HIV transmission. We designed an intervention to explore peer- counselling in reducing high-risk behaviours among newly diagnosed HIV-positive Chinese men who have sex with men (MSM). METHODS: We randomized 367 newly diagnosed HIV-positive men to either standard-of-care (SOC; n = 183) or peer-counselling intervention (n = 184), and followed them for 12 months (visit at 0-, 3-, 6-, 9- and 12-month)...
February 2018: Journal of the International AIDS Society
Yajun Hu, Yinhang Xia, Qi Sun, Kunping Liu, Xiangbi Chen, Tida Ge, Baoli Zhu, Zhenke Zhu, Zhenhua Zhang, Yirong Su
Phosphorus (P) acquisition by plants from soil organic P mainly relies on microorganisms. Examining the community of functional microbes that encode phosphatases (e.g. PhoD) under different fertilization managements may provide valuable information for promoting soil organic P availability. Here, we investigated how the abundance and community diversity of phoD-harboring bacteria responded to long-term fertilization in Karst soils. Six fertilization treatments were designed as follows: non-fertilized control (CK), inorganic fertilization only (NPK), and inorganic fertilization combined with low- and high amounts of straw (LSNPK and HSNPK), or cattle manure (LMNPK and HMNPK)...
February 8, 2018: Science of the Total Environment
Mohamed M Ibrahim, Luke P Poveromo, Richard R Glisson, Agustin Cornejo, Alfredo E Farjat, Ken Gall, Howard Levinson
PURPOSE: Approximately 348,000 ventral hernia repairs are performed annually in the United States and the incisional hernia recurrence rate is approximately 20% as a result of suture and mesh device failure. Device failure is related to changes at the suture/tissue interface that leads to acute or chronic suture pull-through and surgical failure. To better manage mechanical tension, we propose a modified mesh design with extensions and demonstrate its mechanical superiority. METHODS: Comparative uniaxial static tensile testing was conducted on polypropylene suture and a modified mesh...
February 2, 2018: Journal of Biomechanics
Jie Zhang, Juraj Balkovič, Ligia B Azevedo, Rastislav Skalský, Alexander F Bouwman, Guang Xu, Jinzhou Wang, Minggang Xu, Chaoqing Yu
This study analyzes the influence of various fertilizer management practices on crop yield and soil organic carbon (SOC) based on the long-term field observations and modelling. Data covering 11 years from 8 long-term field trials were included, representing a range of typical soil, climate, and agro-ecosystems in China. The process-based model EPIC (Environmental Policy Integrated Climate model) was used to simulate the response of crop yield and SOC to various fertilization regimes. The results showed that the yield and SOC under additional manure application treatment were the highest while the yield under control treatment was the lowest (30%-50% of NPK yield) at all sites...
January 29, 2018: Science of the Total Environment
L Dong, X Chen, H Shao, L Bai, X Li, X Zhang
PURPOSE: We have previously reported that MSCs inhibited experimental autoimmune uveitis (EAU) in rodent models induced by either uveitogenic antigens or antigen-specific T cells. In this study, we explored the inhibitory mechanisms of MSCs on dendritic cells (DCs) in EAU. METHODS: We collected the DCs from the lymph nodes of MSC treated or untreated EAU rats, as well as bone marrow derived DCs cultured in vitro with or without MSC treatment. The levels of costimulatory molecules of CD80, CD86, CD40, OX40L and suppressors of cytokine signaling (SOCS1, SOCS2, and SOCS3) on these DCs were analyzed by flow Cytometry...
February 7, 2018: Current Molecular Medicine
Jan P Unsleber, Johannes Neugebauer, Robert H Morris
Density functional theory (DFT) is used to calculate the relative free energies of deprotonation of the isomers of iron-group hydride complexes MHXL4 where M = Fe, Ru, Os, L4 = (CO)4 or (PMe2CH2CH2PMe2)2 for a wide range of anionic ligands X. The free energies of the most stable isomers are used to calculate relative pKa values where Ka refers to the acid dissociation constant for the equilibrium MHXL4 → [MXL4]- + H+. These are used to test the proposal that the pKa for a given metal complex in THF can be simply calculated by adding the contributions to the total pKa value from each ligand L; these are called ligand acidity constants (LAC) AL used in the LAC equation [R...
February 9, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Xin Yang, Guorong Wen, Biguang Tuo, Fenglian Zhang, Hanxing Wan, Jialin He, Shiming Yang, Hui Dong
Background and Purpose: Although Ca2+ signaling may stimulate small intestinal ion secretion, little is known about its critical role and the molecular mechanisms of Ca2+-mediated biological action. Key Results: Activation of muscarinic receptors by carbachol(CCh) stimulated mouse duodenal Isc, which was significantly inhibited in Ca2+-free serosal solution and by several selective store-operated Ca2+ channels(SOC) blockers added to the serosal side of duodenal tissues...
January 9, 2018: Oncotarget
Joshua A Barocas, Abriana Tasillo, Golnaz Eftekhari Yazdi, Jianing Wang, Claudia Vellozzi, Susan Hariri, Cheryl Isenhour, Liisa Randall, John W Ward, Jonathan Mermin, Joshua A Salomon, Benjamin P Linas
Background: The U.S. Centers for Disease Control and Prevention and the U.S. Preventive Services Task Force recommend one-time hepatitis C virus (HCV) testing for persons born 1945-1965 and targeted testing for high-risk persons. This strategy targets HCV testing to a prevalent population at high risk for HCV morbidity and mortality, but does not include younger populations with high incidence. To address this gap and improve access to HCV testing, age-based strategies should be considered...
February 6, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Fei Shi, Jinying Zhang, Hongyu Liu, Liangliang Wu, Hongyu Jiang, Qiyan Wu, Tianyi Liu, Meiqing Lou, Hao Wu
Glioblastomas (GBMs) are among the most malignant of all human tumors and have poor prognosis. The current standard of care (SOC) includes maximal surgical tumor resection followed by adjuvant temozolomide (TMZ) and concomitant radiotherapy (RT). However, even with this treatment, the 5-year survival rate is less than 10%, and thus, follow-up treatment is required to improve efficacy. In GBMs as well as many other solid cancers, PI3K/mTOR signaling is overactivated. Therefore, multiple tumor-based PI3K inhibitors have been studied in various cancers...
January 2, 2018: Oncotarget
Yurika Kawamura, Ayumi Takayashiki, Makoto Ito, Takami Maeno, Emiko Seo, Tetsuhiro Maeno
Background: Burnout in attending physicians is a crucial issue that may negatively impact patient outcomes, as well as affect the quality of training provided to residents. To investigate the association between burnout and stress-coping ability, we conducted a cross-sectional study of attending physicians. Methods: From April 2013 to March 2014, we distributed an anonymous, self-administered questionnaire to 1,897 attending physicians who attended teaching-related training sessions and workshops...
March 2018: Journal of Clinical Medicine Research
Yupeng Wu, Muhammad Shaaban, Qi' An Peng, An'qi Zhou, Ronggui Hu
Earthworms not only facilitate carbon (C) stabilization, but also accelerate organic matter mineralization by enhancing microbial respiration. However, the fate (mineralization vs stabilization) of newly added C by straw returning in arable lands with earthworm activity is still unclear. In the present 40 days incubation study, we incorporated artificially 13C-labeled straw into soil with and without presence of earthworms (Metaphire guillelmi). Flux measurements of CO2 from soil (mineralization) were taken regularly, while straw-derived C remaining in the soil (stabilization) was measured at the end of the incubation...
February 6, 2018: Environmental Science and Pollution Research International
Gregorio García, Pablo Palacios, Eduardo Menéndez-Proupin, Ana L Montero-Alejo, José C Conesa, Perla Wahnón
Organic-inorganic hybrid halide perovskites compounds are emerging as new materials with great potential for efficient solar cells. This paper explores the possibility of increasing their photovoltaic efficiency through sub-bandgap absorption by way of the in gap band (IGB) concept. Thus, we assess the formation of an in gap band as well as its effect on the absorption features of Organic-inorganic hybrid halide perovskites CH3NH3PbI3 (MAPI). For this task, we use density functional theory (DFT) as well as many-body perturbation methods along to spin-orbit coupling (SOC) to study structural, energetic and electronic properties of partially Cr-substituted MAPI perovskites (CH3NH3Pb1-xCrxI3)...
February 6, 2018: Scientific Reports
Antonio C Arrieta, John S Bradley, Myra W Popejoy, Mekki Bensaci, Anjana Grandhi, Paula Bokesch, Chad Glasser, Lihong Du, Nicholas A Kartsonis
BACKGROUND: Staphylococcus aureus, including community-associated methicillin-resistant S. aureus, is an important cause of pediatric bacteremia. Daptomycin is a well-established treatment option for gram-positive bacteremia in adults, but its safety and efficacy in children require confirmation. METHODS: This was a randomized (2:1), evaluator-blinded, multi-center, phase 4 clinical trial comparing intravenous daptomycin with standard-of-care (SOC) for treatment of S...
February 3, 2018: Pediatric Infectious Disease Journal
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