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https://www.readbyqxmd.com/read/27331804/detection-of-viruses-using-discarded-plants-from-wild-mountain-gorillas-and-golden-monkeys
#1
Tierra Smiley Evans, Kirsten V K Gilardi, Peter A Barry, Benard Jasper Ssebide, Jean Felix Kinani, Fred Nizeyimana, Jean Bosco Noheri, Denis K Byarugaba, Antoine Mudakikwa, Michael R Cranfield, Jonna A K Mazet, Christine K Johnson
Infectious diseases pose one of the most significant threats to the survival of great apes in the wild. The critically endangered mountain gorilla (Gorilla beringei beringei) is at high risk for contracting human pathogens because approximately 60% of the population is habituated to humans to support a thriving ecotourism program. Disease surveillance for human and non-human primate pathogens is important for population health and management of protected primate species. Here, we evaluate discarded plants from mountain gorillas and sympatric golden monkeys (Cercopithecus mitis kandti), as a novel biological sample to detect viruses that are shed orally...
June 22, 2016: American Journal of Primatology
https://www.readbyqxmd.com/read/27303658/history-of-nephrotic-syndrome-and-evolution-of-its-treatment
#2
REVIEW
Abhijeet Pal, Frederick Kaskel
The recognition, evaluation, and early treatment of nephrotic syndrome in infants and children originate from physicians dating back to Hippocrates. It took nearly another 1000 years before the condition was described for its massive edema requiring treatment with herbs and other remedies. A rich history of observations and interpretations followed over the course of centuries until the recognition of the combination of clinical findings of foamy urine and swelling of the body, and measurements of urinary protein and blood analyses showed the phenotypic characteristics of the syndrome that were eventually linked to the early anatomic descriptions from first kidney autopsies and then renal biopsy analyses...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/26779428/a-case-of-gemcitabine-induced-thrombotic-microangiopathy-in-a-urothelial-tumor-patient-with-a-single-kidney
#3
Hyunjin Ryu, Eunjeong Kang, Seokwoo Park, Sehoon Park, Kyoungbun Lee, Kwon Wook Joo, Hajeong Lee
Thrombotic microangiopathy (TMA) is a rare complication of gemcitabine treatment. A 55-year-old man with a history of urothelial cancer underwent right ureteronephrectomy and palliative chemotherapy. The patient presented with dyspnea, generalized edema with foamy urine, and new-onset hypertension with acute kidney injury (AKI). Although AKI with oliguria was evident, thrombocytopenia and hemolytic anemia were not overt. To determine the cause of rapidly progressive azotemia, kidney biopsy was performed despite a single kidney and revealed chronic TMA...
December 2015: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/26591848/lepromatous-leprosy-an-unusual-presentation
#4
S K Gupta, S Kaur, V Malhotra, A K Arora, N Sood, V Gupta
A 25 year old man presented with loss of sensations over both hands and feet and extreme difficulty in passing urine. On examination, an indurated sclerotic plaque was present on shaft of penis and scrotum in addition to other features of lepromatous leprosy. Skin biopsy from the penile lesion showed presence of a large number of acid fast bacilli with a BI of 6+ extending into the epidermis and histopathology showed absence of Grenz zone and presence of foamy macrophages in the dermis up to the dermo-epidermal junction...
January 2015: Indian Journal of Leprosy
https://www.readbyqxmd.com/read/26350293/protective-effects-of-carissa-opaca-fruits-against-ccl4-induced-oxidative-kidney-lipid-peroxidation-and-trauma-in-rat
#5
Sumaira Sahreen, Muhammad Rashid Khan, Rahmat Ali Khan, Huda Mohammad Alkreathy
BACKGROUND: Carbon tetrachloride (CCl4) is a potent nephrotoxin, as it causes acute as well as chronic toxicity in kidneys. Therefore, this study was carried out to assess the pharmacological potential of different fractions of Carissa opaca fruits on CCl4-induced oxidative trauma in the kidney. METHODS: The parameters studied in this respect were the kidney function tests viz, serum profile, urine profile, genotoxicity, characteristic morphological findings, and antioxidant enzymatic level of kidneys...
2015: Food & Nutrition Research
https://www.readbyqxmd.com/read/26064498/foamy-urine-in-nephrotic-syndrome
#6
Márcio Dantas, Gyl E Barros Silva, Miguel Moysés-Neto
No abstract text is available yet for this article.
June 2013: Clinical Kidney Journal
https://www.readbyqxmd.com/read/25684013/rifampicin-induced-minimal-change-disease-is-improved-after-cessation-of-rifampicin-without-steroid-therapy
#7
Dong Hyuk Park, Sul A Lee, Hyeon Joo Jeong, Tae-Hyun Yoo, Shin-Wook Kang, Hyung Jung Oh
There are several reports to demonstrate that rifampicin, a major anti-tuberculosis agent, is associated with some adverse renal effects, with a few cases of rifampicin-induced minimal change disease (MCD). In the present case, a 68-year-old female presented with nausea, vomiting, foamy urine, general weakness and edema. She had been taking rifampicin for 4 weeks due to pleural tuberculosis. The patient had no proteinuria before the anti-tuberculosis agents were started, but urine tests upon admission showed heavy proteinuria with a 24-h urinary protein of 9...
March 2015: Yonsei Medical Journal
https://www.readbyqxmd.com/read/25327101/teenager-male-with-burning-pain-in-extremities-suspect-fabry-disease-2-case-reports
#8
Rajesh B Patil, V K Joglekar
INTRODUCTION: We present 2 cases of teenager males presented with burning pain in extremities and turned out to be cases of Fabry disease.The purpose of presenting this case is to highlight the fact that suspicion of Fabry disease in patients presenting with these symptoms will lead to early diagnosis and treatment of this condition before occurrences of complications. CASE REPORT 1: A 14-year-old male presented with severe burning pain in both hands and feet since last 4 yrs which persisted despite consumption of painkillers and becoming more disabling and without having any family history for such condition...
January 2014: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/25070574/light-chain-multiple-myeloma-clinic-features-responses-to-therapy-and-survival-in-a-long-term-study
#9
Jia-jia Zhang, Wan-jun Sun, Zhong-xia Huang, Shi-lun Chen, Yu-ping Zhong, Ying Hu, Na An, Men Shen, Xin Li
BACKGROUND: We intended to investigate the long-term clinical characteristics, responses to therapy and survival in patients with lightchain multiple myeloma (MM). METHODS: Ninety-six patients were enrolled into the study. There were 42 κ-chain MM patients and 54 λ-chain MM patients. All the patients werestage III in the Durie-Salmonstaging system. Among them, 66 patients received Velcade (bortezomib) treatment and the other 30 did not. RESULTS: The main symptoms of these patients included bone pain (77...
2014: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/24878648/clinical-characteristics-of-chronic-kidney-disease-of-nontraditional-causes-in-salvadoran-farming-communities
#10
Raúl Herrera, Carlos M Orantes, Miguel Almaguer, Pedro Alfonso, Héctor D Bayarre, Irma M Leiva, Magaly J Smith, Ricardo A Cubias, Carlos G Torres, Walter O Almendárez, Francisco R Cubias, Fabrizio E Morales, Salvador Magaña, Juan C Amaya, Edgard Perdomo, Mercedes C Ventura, Juan F Villatoro, Xavier F Vela, Susana M Zelaya, Delmy V Granados, Eduardo Vela, Patricia Orellana, Reynaldo Hevia, E Jackeline Fuentes, Reinaldo Mañalich, Raymed Bacallao, Mario Ugarte, María I Arias, Jackelin Chávez, Nelson E Flores, Claudia E Aparicio
INTRODUCTION: Chronic kidney disease is a serious health problem in El Salvador. Since the 1990s, there has been an increase in cases unassociated with traditional risk factors. It is the second leading cause of death in men aged >18 years. In 2009, it was the first cause of in-hospital death for men and the fifth for women. The disease has not been thoroughly studied. OBJECTIVE: Characterize clinical manifestations (including extrarenal) and pathophysiology of chronic kidney disease of nontraditional causes in Salvadoran farming communities...
April 2014: MEDICC Review
https://www.readbyqxmd.com/read/23913314/a-case-of-fabry-nephropathy-with-histological-features-of-oligonephropathy
#11
Masashi Nishida, Kitaro Kosaka, Koh Hasegawa, Kousuke Nishikawa, Toshiyuki Itoi, Takahiro Tsukimura, Tadayasu Togawa, Hitoshi Sakuraba, Kenji Hamaoka
UNLABELLED: Newborn screening studies indicate the expected high incidence of later-onset Fabry disease with silent Fabry nephropathy while, with recent improved clinical care of premature infants, children with congenital oligonephropathy caused by premature embryonal development of the kidney are thought to be increasing. However, the coexistence of Fabry nephropathy and oligonephropathy has not been reported previously. We present the case of a 13-year-old boy who was diagnosed with Fabry nephropathy accompanied with histological features of oligonephropathy...
August 2014: European Journal of Pediatrics
https://www.readbyqxmd.com/read/23898812/a-metabonomic-approach-to-the-investigation-of-drug-induced-phospholipidosis-an-nmr-spectroscopy-and-pattern-recognition-study
#12
Andrew W Nicholls Jeremy K Nicholson John N Haselden Catherine J Waterfield
(1)H NMR spectroscopy of urine and pattern recognition analysis have been used to study the metabolic perturbations caused following dosing of five novel drug candidates, two of which (GWA, GWB) caused mild lung and liver phospholipidosis, whilst the rest (GWC-GWE) did not cause any detectable toxicity. Urine samples were collected predose, 0-8 h, 8-16 h, 16-24 h and 24-32 h after single, oral dosing with each compound to Han Wistar rats (n = 3 per group), and liver and lung samples for were taken at 48 h for histology...
2000: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/23738410/xanthogranulomatous-pyelonephritis-in-a-male-child-a-case-report-with-a-brief-review-of-literature
#13
REVIEW
Reech Singh, Geetanjali Gupta, Pradeep Kumar, Dhananjay S Kotasthane
Xanthogranulomatous pyelonephritis is a rare type of renal infection characterised by granulomatous inflammation with giant cells and foamy histiocytes.The peak incidence is in the sixth to seventh decade with a female to male ratio of 2:1. It is rare in children. A case of xanthogranulomatous pyelonephritis in a 11-year-old male child who presented with a history of high grade fever and chills for 15 days, right flank pain and progressive pyuria for two months is reported. He had a prior history of surgery for vesical calculus and anterior urethral calculus for which he underwent open cystolithotomy and urethrolithotomy four years back...
October 2012: Journal of the Indian Medical Association
https://www.readbyqxmd.com/read/23441457/-diagnosis-and-treatment-of-xanthogranulomatous-prostatitis-a-case-report-and-review-of-the-literature
#14
REVIEW
Ying Wang, Hai-Long Hu, Zhi-Fei Liu, Wei-Zong Sun, Xing-Xi Chen, Chang-Li Wu
OBJECTIVE: To explore the diagnosis and treatment of xanthogranulomatous prostatitis. METHODS: A 75-year-old man presented with a 3-month history of difficult urination and frequent micturition, which was exacerbated for 2 days. Digital rectal examination indicated an enlarged prostate size of II degrees with hard texture but no tenderness. Serum total PSA was 172.5 microg/L. TRUS revealed 200 ml of post-micturition residual urine, thickened bladder wall, prostate size of 4...
February 2013: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/23323222/clinical-significance-of-subjective-foamy-urine
#15
Kyu Keun Kang, Jung Ran Choi, Ji Young Song, Sung Wan Han, So Hyun Park, Woong Sun Yoo, Hwe Won Kim, Dongyoung Lee, Kyoung Hyoub Moon, Myung Hee Lee, Beom Kim
Foamy urine is widely regarded as a sign of proteinuria. However, there is no objective definition of foamy urine and there are no reports on the proportion of involved patients who have overt proteinuria or microalbuminuria. We performed this study to investigate this proportion and to identify possible risk factors for these two conditions. We reviewed all new outpatients from 1 November 2011 to 30 April 2012 and identified patients complaining of foamy urine. Their demographic data and medical records were examined...
December 2012: Chonnam Medical Journal
https://www.readbyqxmd.com/read/23242145/prevalence-and-accompanying-signs-of-pneumovagina-and-urovagina-in-dairy-cows-in-the-southern-marmara-region
#16
G Goncagul, K Seyrek Intas, I H Kumru, D Seyrek Intas
OBJECTIVE: Studies on the prevalence of pneumo- and urovagina in cows are rare. The aim of this study was to determine the prevalence and the most common accompanying clinical signs of pneumo- and urovagina in dairy cows. MATERIAL AND METHODS: Between 2007 and 2010 a total of 1167 Holstein and Brown Swiss cows were examined clinically and bacteriologically. Pneumovagina was diagnosed if air was sucked in or expelled from the vagina spontaneously at any time. Urovagina was defined as the accumulation of urine at the fornix of the vagina...
2012: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/23195831/diffuse-parenchymal-form-of-malakoplakia-in-renal-transplant-recipient-a-case-report
#17
Elizete Keitel, Karla Lais Pêgas, Antonio Eduardo do Nascimento Bittar, Auri Ferreira dos Santos, Francisco da Cas Porto, Eduardo Cambruzzi
Malakoplakia is an unusual chronic inflammatory disease related to prior urinary tract infection. It is characterized by the presence of macrophages with foamy cytoplasm exhibiting larger PAS positive inclusions that stain for calcium and iron. Malakoplakia affects renal allograft and is associated with severe morbidity. Herein, the authors report a new case of renal graft malakoplakia in a 23-year-old female patient. The patient received a living-related donor renal transplantation with a high immunological risk...
June 2014: Clinical Nephrology
https://www.readbyqxmd.com/read/23060730/a-case-of-tubulointerstitial-nephritis-and-uveitis-syndrome-in-an-elderly-patient
#18
Jeong Mo Han, Yun Jong Lee, Se Joon Woo
Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare disease entity usually occurring in children. In the present study a case of TINU syndrome in an elderly patient is described and relevant literature is reviewed. A 61-year-old man presented with bilateral flank pain, urinary frequency, and foamy urine. A kidney ultrasonography revealed an increase in kidney parenchyma echogenicity. Following a kidney biopsy, the patient was diagnosed with acute tubulointerstitial nephritis. An ophthalmology examination initially performed for floater symptoms, revealed anterior uveitis in both eyes...
October 2012: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/22417126/fibrillary-glomerulonephritis-associated-with-beh%C3%A3-et-s-syndrome
#19
Hyun Ju Kim, Sun Woo Kang, Seok Ju Park, Tae Hee Kim, Mi Seon Kang, Yeong Hoon Kim
Fibrillary glomerulonephritis (FGN) is a rare cause of progressive renal dysfunction resulting in fibrillary deposits in the mesangium and/or glomerular basement membrane (GBM). Some case reports have shown FGN in patients with rheumatoid arthritis and other autoimmune diseases. This is the first case report of FGN in a patient with Behçet's syndrome. The most common renal histological finding in Behçet's syndrome is secondary amyloidosis. A 46-year-old woman with a 4-year history of Behçet's syndrome was referred to the nephrology clinic with foamy urine with non-selective proteinuria (urine protein-to-creatinine ratio was 1400 mg protein/g creatinine) and microscopic hematuria...
2012: Renal Failure
https://www.readbyqxmd.com/read/21316534/telavancin-a-lipoglycopeptide-antimicrobial-for-the-treatment-of-complicated-skin-and-skin-structure-infections-caused-by-gram-positive-bacteria-in-adults
#20
REVIEW
Mei H Chang, Troy D Kish, Horatio B Fung
BACKGROUND: Telavancin, a lipoglycopeptide antibiotic, is a semisynthetic derivative of vancomycin. It was approved by the US Food and Drug Administration (FDA) in 2009 for the treatment of complicated skin and skin structure infections (cSSSIs) caused by gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. OBJECTIVE: This article summarizes the pharmacology, in vitro and in vivo activity, pharmacokinetic properties, and clinical efficacy and tolerability of telavancin...
December 2010: Clinical Therapeutics
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