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https://www.readbyqxmd.com/read/29778430/does-periurethral-cleaning-with-water-prior-to-indwelling-urinary-catheterization-increase-the-risk-of-urinary-tract-infections-a-systematic-review-and-meta-analysis
#1
REVIEW
Kun Huang, Jihong Liang, Ting Mo, Yanli Zhou, Yanping Ying
OBJECTIVE: To determine whether periurethral cleaning with water before indwelling urinary catheterization increases the risk of urinary tract infections (UTIs) compared with studies using anti-infective agents. METHODS: A literature search via MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials through October 2017 and a manual search of references for additional relevant studies. Trials studying clean intermittent catheterization were excluded...
May 16, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29775686/the-comparative-efficacy-of-antiseptics-against-candida-auris-biofilms
#2
Ryan Kean, Emily McKloud, Eleanor M Townsend, Leighann Sherry, Christopher Delaney, Brian L Jones, Craig Williams, Gordon Ramage
Candida auris has emerged as a significant clinical entity due to its ability to cause outbreaks within the healthcare setting. A key feature of its nosocomial lifestyle is its ability to transfer between patients, yet little is known about the mechanisms behind this. A panel of C. auris clinical isolates was screened for their planktonic and sessile susceptibilities to skin disinfection challenge using povidone iodine, chlorhexidine and hydrogen peroxide. C. auris biofilms displayed increased tolerance to these strategies compared to planktonic cells...
May 15, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29761329/bactericidal-and-virucidal-activity-of-povidone-iodine-and-chlorhexidine-gluconate-cleansers-in-an-in-vivo-hand-hygiene-clinical-simulation-study
#3
Maren Eggers, Torsten Koburger-Janssen, Lois S Ward, Craig Newby, Stefan Müller
INTRODUCTION: Standard in vitro and in vivo tests help demonstrate efficacy of hand hygiene products; however, there is no standard in vivo test method for viruses. We investigated the bactericidal and virucidal efficacy of povidone-iodine (PVP-I) 7.5% scalp and skin cleanser, chlorhexidine gluconate (CHG) 4% hand cleanser and the reference hand wash (soft soap) in 15 healthy volunteers following European Standard EN1499 (hygienic hand wash test method for bacteria), which was adapted for virucidal testing...
May 14, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29753031/antiseptic-agents-elicit-short-term-personalized-and-body-site-specific-shifts-in-resident-skin-bacterial-communities
#4
Adam J SanMiguel, Jacquelyn S Meisel, Joseph Horwinski, Qi Zheng, Charles W Bradley, Elizabeth A Grice
Despite critical functions in cutaneous health and disease, it is unclear how resident skin microbial communities are altered by topical antimicrobial interventions commonly used in personal and clinical settings. Here we show that acute exposure to antiseptic treatments elicits rapid but short-term depletion of microbial community diversity and membership. Thirteen subjects were enrolled in a longitudinal treatment study to analyze the effects of topical treatments (ethanol, povidone-iodine, chlorhexidine, water) on the skin microbiome at two skin sites of disparate microenvironment: forearm and back...
May 9, 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29738292/comparison-of-antimicrobial-activity-of-selected-commercially-available-wound-dressing-materials
#5
Piotr Szweda, Grzegorz Gorczyca, Robert Tylingo
OBJECTIVE: The aim of our study was to examine the antimicrobial potential of eight selected, commercially available wound dressings containing different antimicrobial agents: silver, chlorhexidine acetate, povidone-iodine, and manuka honey. METHOD: The materials were tested against four reference strains of bacteria: Staphylococcus aureus (PCM 2051), Staphylococcus epidermidis (PCM 2118), Pseudomonas aeruginosa (ATCC 27853), and Escherichia coli (K12), using the disc diffusion-like method and a time-killing assay...
May 2, 2018: Journal of Wound Care
https://www.readbyqxmd.com/read/29704562/a-survey-to-identify-the-breach-between-evidence-and-practice-in-the-prevention-of-surgical-infection-time-to-take-action
#6
REVIEW
Josep M Badia, Anna L Casey, Inés Rubio-Pérez, Cynthia Crosby, Nares Arroyo-García, José Balibrea Del Castillo
BACKGROUND: The knowledge of the grade of implementation of preventative measures for surgical site infection (SSI) is crucial prior to planning dissemination strategies. METHODS: Online survey among the members of the Spanish Association of Surgeons (AEC) to know the actual application of measures, and to compare them with new recommendations issued by international organizations. RESULTS: Most of the 835 responding surgeons work in National Health Service Hospitals (91...
April 25, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29627326/one-percent-chlorhexidine-alcohol-for-preventing-central-venous-catheter-related-infection-during-intensive-chemotherapy-for-patients-with-haematologic-malignancies
#7
Shimon Ohtake, Hiromichi Takahashi, Masaru Nakagawa, Yoshihito Uchino, Katsuhiro Miura, Noriyoshi Iriyama, Tomohiro Nakayama, Yoshihiro Hatta, Masami Takei
A central venous catheter (CVC) is a catheter placed into a large vein, and is used for chemotherapy administration. However, there is little confirmatory data on which antiseptic-such as chlorhexidine or povidone-iodine (PI) -is more protective against CVC-related infectious complications in patients receiving intensive chemotherapy. We aimed to compare the effectiveness of 1% chlorhexidine gluconate in 70% alcohol (CH) vs. PI for skin disinfection before CVC insertion in patients receiving intensive chemotherapy...
April 4, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29573800/short-communication-the-effect-of-novel-antiseptic-compounds-on-umbilical-cord-healing-and-incidence-of-infection-in-dairy-calves
#8
A L Fordyce, L L Timms, K J Stalder, H D Tyler
The goal of dipping the umbilical cord after birth in calves is to promote healing of the umbilical stump, prevent infection, and encourage the umbilical tissue to detach from the body. Treatment applied to the umbilical area is an important management step for preventing morbidity and mortality in calves. The objective of this study was to compare the effect of 4 umbilical dips on the healing rate, incidence of infection, and age at umbilical cord detachment using newborn Holstein heifer calves (n = 73). Calves were alternately assigned by birth order to 4 treatment groups: 7% iodine, a dry dip formulated using an antibacterial peptide (nisin) mixed with talc (3...
March 21, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29540169/skin-asepsis-protocols-as-a-preventive-measure-of-surgical-site-infections-in-dogs-chlorhexidine-alcohol-versus-povidone-iodine
#9
Luís Belo, Isa Serrano, Eva Cunha, Carla Carneiro, Luis Tavares, L Miguel Carreira, Manuela Oliveira
BACKGROUND: Most of surgical site infections (SSI) are caused by commensal and pathogenic agents from the patient's microbiota, which may include antibiotic resistant strains. Pre-surgical asepsis of the skin is one of the preventive measures performed to reduce SSI incidence and also antibiotic resistance dissemination. However, in veterinary medicine there is no agreement on which biocide is the most effective. The aim of this study was to evaluate the effectiveness of two pre-surgical skin asepsis protocols in dogs...
March 14, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29490694/systematic-review-of-ototoxic-pre-surgical-antiseptic-preparations-what-is-the-evidence
#10
REVIEW
Shubhi Singh, Brian Blakley
OBJECTIVE: There is uncertainty regarding the safety of surgical antiseptic preparations in the ear. A systematic review of the literature was conducted to assess the evidence regarding ototoxicity of surgical antiseptic preparations. METHODS: A literature search was conducted using the PRISMA methods. Key words included "ototoxicity" "hearing loss", "antiseptic", "surgical preparation", "tympanoplasty", "vestibular dysfunction", "chlorhexidine", "iodine", "povidone", "ethanol", and "hydrogen peroxide" using Medline, Embase, Cochrane Library, Scopus and Web of Science...
March 1, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29447075/propionibacterium-acnes-has-low-susceptibility-to-chlorhexidine-digluconate
#11
Keisuke Nakase, Hanae Fukushima, Tomoko Yukawa, Hidemasa Nakaminami, Takeshi Fujii, Norihisa Noguchi
BACKGROUND: The skin bacterium Propionibacterium acnes has been reported to be responsible for surgical site infections (SSIs). Skin disinfection before surgery therefore is of the utmost importance in the prevention of SSIs caused by skin bacteria. METHODS: We assessed the susceptibility of clinical isolates of two skin bacteria, P. acnes and Staphylococcus epidermidis, to disinfectants. RESULTS: The range of chlorhexidine digluconate (CHG) minimum inhibitory concentrations (MICs) for P...
April 2018: Surgical Infections
https://www.readbyqxmd.com/read/29443852/chlorhexidine-antiseptic-irrigation-eradicates-staphylococcus-epidermidis-from-biofilm-an-in-vitro-study
#12
Kenneth Schmidt, Chris Estes, Alex McLaren, Mark J Spangehl
BACKGROUND: Antiseptic and antibacterial solutions used for intraoperative irrigation are intended to kill bacteria and thereby decrease the incidence of surgical site infections. It is unknown if the concentrations and exposure times of irrigation solutions commonly used for prophylaxis in clean cases (povidone-iodine 0.35% for 3 minutes) are effective against bacteria in biofilm that are present in implant infections. Currently, povidone-iodine (0.35%), chlorhexidine (0.05%), sodium hypochlorite (0...
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29425078/pre-operative-skin-antisepsis-with-chlorhexidine-gluconate-and-povidone-iodine-to-prevent-port-site-infection-in-laparoscopic-cholecystectomy-a-prospective-study
#13
Erasmo Spaziani, Annalisa Di Filippo, Simone Orelli, Flavia Fiorini, Martina Spaziani, Orlando Tintisona, Angelo Torcasio, Alessandro De Cesare, Marcello Picchio
BACKGROUND: Skin preparation with antiseptic agents is commonly recommended for incisional site cleansing before surgery. We present the result of a prospective case series submitted to a scheduled pre-operative antiseptic procedure combining chlorhexidine gluconate and povidone-iodine before elective laparoscopic cholecystectomy. PATIENTS AND METHODS: Consecutive patients underwent pre-operative standardized cleansing of the operation site combining chlorhexidine gluconate and povidone-iodine...
April 2018: Surgical Infections
https://www.readbyqxmd.com/read/29398812/evaluation-of-the-role-of-novel-aprotic-dimethyl-sulfoxide-in-cutaneous-antisepsis-protocols-prior-to-blood-donor-phlebotomy-with-isopropyl-alcohol-povidone-iodine-or-chlorhexidine
#14
Suchet Sachdev, Nandini Sethuraman, Vikas Gautam, Deepak Pahwa, Anuradha Kalra, Ratti Ram Sharma, Neelam Marwaha, Pallab Ray
The study was planned to measure the reduction of the load of bacterial flora on the blood donor's arm quantitatively using a three step protocol of donor arm cleansing incorporating either 70% isopropyl alcohol (IPA) or 5% w/v povidone iodine (PVI, 0.5% w/v available iodine) or 4% chlorhexidine gluconate (CHG) with or without the addition of 5% dimethyl sufloxide (DMSO). Single blind randomized study after obtaining ethical clearance, using the Miles and Misra technique for quantification and matrix assisted laser desorption ionization-mass spectrometry for identification of colony morphotypes on blood donor's skin...
January 2018: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/29373294/propionibacterium-acnes-suture-contamination-in-arthroscopic-rotator-cuff-repair-a-prospective-randomized-study
#15
Kotaro Yamakado
PURPOSE: To examine the contamination rate of the anchor-suture and to determine the efficacy of 2 different surgical skin preparation solutions with or without a plastic adhesive drape from suture contamination in arthroscopic rotator cuff repair. METHODS: A prospective randomized study was undertaken to evaluate 126 consecutive patients undergoing arthroscopic rotator cuff repair. Each shoulder was prepared with one of 2 randomly selected solutions according to an assigned envelope that indicated the procedure to be used: chlorhexidine-alcohol (1% chlorhexidine gluconate and 70% isopropyl alcohol) or povidone-iodine...
April 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29340748/lack-of-level-i-evidence-on-how-to-prevent-infection-after-elective-shoulder-surgery
#16
Carola F Eck, Julie A Neumann, Orr Limpisvasti, Christopher R Adams
PURPOSE: Infection is a concern after all orthopedic procedures, including shoulder surgery. This systematic review of literature aimed to determine risk factors for infection as well as the availability and effectiveness of measures utilized to prevent infection after elective shoulder surgery. METHODS: An electronic database search was performed using MEDLINE (1950-October 2017), EMBASE (1980-October 2017), CINAHL (1982-October 2017), and the Cochrane database to identify studies reporting a risk factor or preventive measure for infection after shoulder surgery...
January 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29317910/impact-of-choice-of-skin-preparation-solution-in-cardiac-surgery-on-rate-of-surgical-site-infection-a-propensity-score-matched-analysis
#17
Shahzad G Raja, Melissa Rochon, Clair Mullins, Carlos Morais, Antonios Kourliouros, Ellie Wishart, Anthony De Souza, Sunil Bhudia
Background: Antiseptic skin preparations containing chlorhexidine gluconate and povidone iodine are routinely used to reduce the risk of surgical site infection (SSI). This study assesses the efficacy of two alcohol-based solutions, 2% chlorhexidine-alcohol and 10% povidone iodine-alcohol, on the incidence of cardiac SSI. Methods: A total of 738 consecutive patients undergoing cardiac surgery had skin preparation with 2% chlorhexidine gluconate in 70% isopropanol (ChloraPrep, BD Ltd, UK) were propensity matched to 738 patients with skin prepared with 10% povidone-iodine in 30% industrial methylated spirit (Videne Alcoholic Tincture, Ecolab Ltd, UK)...
January 2018: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29316457/topical-chlorhexidine-povidone-iodine-and-erythromycin-in-the-repair-of-traumatic-ulcers-on-the-rat-tongue-clinical-histological-and-microbiological-evaluation
#18
Dieni da Silveira Teixeira, Maria Antonia Zancanaro de Figueiredo, Karen Cherubini, Maria Claudia Rosa Garcia, Sílvia Dias de Oliveira, Fernanda Gonçalves Salum
OBJECTIVE: This study investigated the effect of topical application of 0.12% chlorhexidine, 10% povidone-iodine and 50% erythromycin on the optimization of healing process of traumatic ulcers made on ventral tongue of rats. DESIGN: Forty-Eight Wistar rats were randomly divided into four groups: control, chlorhexidine (Chx), povidone-iodine (PvI) and erythromycin (Er). An ulcer of 5 mm in diameter was made on the ventral tongue of the animals. After 24 h, a microbiological sample was taken and daily application of the substances started...
March 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29313865/evaluation-of-emdogain%C3%A2-antimicrobial-effectiveness-against-biofilms-containing-the-keystone-pathogen-porphyromonas-gingivalis
#19
Jérôme Lasserre, Selena Toma, Ana-Maria Dos Santos-Gonçalvez, Julian Leprince, Gaëtane Leloup, Michel Brecx
This study aimed to evaluate the antimicrobial activity of Emdogain® (EMD) against biofilms containing the periopathogen Porphyromonas gingivalis. A brain-Heart infusion broth inoculated with S. gordonii and P. gingivalis was perfused (7-d, anaerobiosis) through a closed circuit containing two Robbins devices as to form biofilms. The latter were then treated for 2 min with various antimicrobials (Chlorhexidine (CHX) 0.2%, Povidone iodine (PVI) 5%, PVI 10%, essential oils (EO), EO ZeroTM or EMD) (n=8) and cell densities were calculated and compared...
January 2018: New Microbiologica
https://www.readbyqxmd.com/read/29290346/predictive-factors-of-catheter-related-bloodstream-infection-in-patients-receiving-home-parenteral-nutrition
#20
Orawan Pichitchaipitak, Sineenuch Ckumdee, Siriluk Apivanich, Darunee Chotiprasitsakul, Prapimporn Chattranukulchai Shantavasinkul
OBJECTIVES: The aim of this study was to determine the incidence and predictive factors of catheter-related bloodstream infections (CRBSIs) acquired through a central venous catheter for delivery of home parenteral nutrition (HPN) therapy among a patient population in Thailand. METHODS: This retrospective review was conducted with adult patients with intestinal failure who received HPN from October 2002 to April 2014, at Ramathibodi Home Parenteral and Enteral Nutrition Referral Center in Bangkok...
February 2018: Nutrition
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