Elisangela G Cata-Preta, Yasmim A Serra, Eliseu da C Moreira-Junior, Henrique S Reis, Natali D Kisaki, Matheus Libarino-Santos, Raiany R R Silva, Thaísa Barros-Santos, Lucas C Santos, Paulo C R Barbosa, José L Costa, Alexandre J Oliveira-Lima, Lais F Berro, Eduardo A V Marinho
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- and N,N -dimethyltryptamine(DMT)-containing plants, respectively. Accumulating evidence suggests that ayahuasca may have therapeutic effects on ethanol abuse. It is not known, however, whether its effects are dependent on the presence of DMT or if non-DMT-containing components would have therapeutic effects. The aim of the present study was to investigate the rewarding properties of ayahuasca (30, 100, and 300 mg/kg, orally), Bc (132, 440, and 1320 mg/kg, orally) and Pv (3...
2018: Frontiers in Pharmacology