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https://www.readbyqxmd.com/read/29245141/a-systematic-review-of-the-state-of-the-literature-on-sexually-exploited-boys-internationally
#1
Melissa Moynihan, Katherine Mitchell, Claire Pitcher, Farinaz Havaei, Max Ferguson, Elizabeth Saewyc
This systematic review assessed the current state of the literature on sexually exploited boys internationally. We aimed to describe what is known about sexual exploitation of boys, identify gaps in the literature, provide implications for practice, and make recommendations for future research. Multiple database searches were conducted using a combination of controlled vocabulary and keywords to capture child and adolescent sexual exploitation. Our search identified 11,099 unique references and excluded studies that did not include male participants less than 18 years old or disaggregate results by relevant age groups and/or by sex...
December 12, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29244988/chemotherapy-use-at-the-end-of-life-in-uganda
#2
Daniel Low, Emily C Merkel, Manoj Menon, Gary H Lyman, Henry Ddungu, Elizabeth Namukwaya, Mhoira Leng, Corey Casper
Purpose Avoiding chemotherapy during the last 30 days of life has become a goal of cancer care in the United States and Europe, yet end-of-life chemotherapy administration remains a common practice worldwide. The purpose of this study was to determine the frequency of and factors predicting end-of-life chemotherapy administration in Uganda. Methods Retrospective chart review and surveys and interviews of providers were performed at the Uganda Cancer Institute (UCI), the only comprehensive cancer center in the area, which serves a catchment area of greater than 100 million people...
December 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29244986/breast-cancer-in-ghana-demonstrating-the-need-for-population-based-cancer-registries-in-low-and-middle-income-countries
#3
Abigail S Thomas, Kelley M Kidwell, Joseph K Oppong, Ernest K Adjei, Ernest Osei-Bonsu, Angela Boahene, Evelyn Jiggae, Kofi Gyan, Sofia D Merajver
Purpose Breast cancer, the most common cancer worldwide, is the leading cause of cancer mortality in Ghanaian women. Previous studies find Ghanaian women are diagnosed at a younger age and at more advanced stages (III and IV), and have tumors with characteristics similar to African American women. We sought to remedy gaps in knowledge about breast cancer survival in Ghana and its relation to demographic and biologic factors of the tumors at diagnosis to assist in cancer control and registration planning. Methods Individuals with a breast cancer diagnosis who sought care at Komfo Anokye Teaching Hospital from 2009 to 2014 were identified via medical records...
December 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29244985/malignancy-related-hypercalcemia-in-advanced-solid-tumors-survival-outcomes
#4
Ricardo Emanuel de Oliveira Ramos, Milena Perez Mak, Michel Fabiano Silva Alves, Gustavo Henrique Munhoz Piotto, Tiago Kenji Takahashi, Leonardo Gomes da Fonseca, Marina Cavalcanti Maroja Silvino, Paulo Marcelo Hoff, Gilberto de Castro
Purpose Malignancy-related hypercalcemia (MRH) is associated with a dismal prognosis. The widespread use of bisphosphonates (BPs), availability of more effective drugs in cancer treatment, and improvement in supportive care might have attenuated its impact. Patients and Methods To assess overall survival (OS) of patients with MRH in a contemporary setting, we conducted a retrospective analysis of 306 patients with solid cancer hospitalized for symptomatic hypercalcemia. A multivariable Cox proportional hazards regression model was performed to evaluate possible prognostic factors associated with MRH...
December 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29244874/maximum-walking-speed-in-multiple-sclerosis-assessed-with-visual-perceptive-computing
#5
Anuschka Grobelny, Janina R Behrens, Sebastian Mertens, Karen Otte, Sebastian Mansow-Model, Theresa Krüger, Elona Gusho, Judith Bellmann-Strobl, Friedemann Paul, Alexander U Brandt, Tanja Schmitz-Hübsch
BACKGROUND: Gait is often impaired in people with multiple sclerosis (PwMS), but detailed assessment of gait impairment in research and care remains challenging. In a previous pilot study we reported the feasibility of visual perceptive computing (VPC) for gait assessment in PwMS using the Short Maximum Speed Walk (SMSW), which assesses gait on recording distances confined to less than 4 meters. OBJECTIVE: To investigate the equivalence of SMSW to rater-based timed 25ft...
2017: PloS One
https://www.readbyqxmd.com/read/29244837/frailty-and-quality-of-life-among-older-people-with-and-without-a-cancer-diagnosis-findings-from-topics-mds
#6
Noralie Geessink, Yvonne Schoon, Harry van Goor, Marcel Olde Rikkert, René Melis
BACKGROUND: The number of older cancer patients is rising. Especially in older people, treatment considerations should balance the impact of disease and treatment on quality of life (QOL) and survival. How a cancer diagnosis in older people interacts with concomitant frailty to impact on QOL is largely unknown. We aimed to determine the association between frailty and QOL among community-dwelling older people aged 65 years or above with and without a cancer diagnosis cross-sectionally and at 12 months follow-up...
2017: PloS One
https://www.readbyqxmd.com/read/29244776/internet-of-things-iot-based-design-of-a-secure-and-lightweight-body-area-network-ban-healthcare-system
#7
Yong-Yuan Deng, Chin-Ling Chen, Woei-Jiunn Tsaur, Yung-Wen Tang, Jung-Hsuan Chen
As sensor networks and cloud computation technologies have rapidly developed over recent years, many services and applications integrating these technologies into daily life have come together as an Internet of Things (IoT). At the same time, aging populations have increased the need for expanded and more efficient elderly care services. Fortunately, elderly people can now wear sensing devices which relay data to a personal wireless device, forming a body area network (BAN). These personal wireless devices collect and integrate patients' personal physiological data, and then transmit the data to the backend of the network for related diagnostics...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244735/development-of-the-precision-link-biobank-at-boston-children-s-hospital-challenges-and-opportunities
#8
REVIEW
Florence T Bourgeois, Paul Avillach, Sek Won Kong, Michelle M Heinz, Tram A Tran, Ramkrishna Chakrabarty, Jonathan Bickel, Piotr Sliz, Erin M Borglund, Susan Kornetsky, Kenneth D Mandl
Increasingly, biobanks are being developed to support organized collections of biological specimens and associated clinical information on broadly consented, diverse patient populations. We describe the implementation of a pediatric biobank, comprised of a fully-informed patient cohort linking specimens to phenotypic data derived from electronic health records (EHR). The Biobank was launched after multiple stakeholders' input and implemented initially in a pilot phase before hospital-wide expansion in 2016...
December 15, 2017: Journal of Personalized Medicine
https://www.readbyqxmd.com/read/29244560/sex-specific-heterogeneity-in-fixed-morphological-traits-influences-individual-fitness-in-a-monogamous-bird-population
#9
Floriane Plard, Susanne Schindler, Raphaël Arlettaz, Michael Schaub
Theoretical work has emphasized the important role of individual traits on population dynamics, but empirical models are often based on average or stage-dependent demographic rates. In this study on a monogamous bird, the Eurasian hoopoe (Upupa epops), we show how the interactions between male and female fixed and dynamic heterogeneity influence demographic rates and population dynamics. We built an integral projection model including individual sex, age, condition (reflecting dynamic heterogeneity), and fixed morphology (reflecting fixed heterogeneity)...
January 2018: American Naturalist
https://www.readbyqxmd.com/read/29244214/mixed-viral-infections-of-the-respiratory-tract-an-epidemiological-study-during-consecutive-winter-seasons
#10
Emmanouil Antalis, Zacharoula Oikonomopoulou, Christine Kottaridi, Athanasios Kossyvakis, Aris Spathis, Maria Magkana, Aikaterini Katsouli, Vassileios Tsagris, Vassiliki Papaevangelou, Andreas Mentis, Sotirios Tsiodras
Introduction The current study aimed to describe the molecular epidemiology of mixed respiratory viral infections during consecutive winter seasons in a tertiary care hospital. Methods Patients with symptoms of respiratory tract infection were evaluated during the 2009-2011 and 2013-15 winter seasons. A clinical microarray technique was used for viral detection. Clinical and epidemiological data were correlated with mixed viral detection and the need for hospitalization. Results In 332 out of 604 (54.4%) evaluated patients (17...
December 15, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29244150/risk-and-prognostic-factors-for-multiple-primary-carcinomas-in-patients-with-head-and-neck-cancer
#11
Seiji Hosokawa, Goro Takahashi, Jun Okamura, Atsushi Imai, Daiki Mochizuki, Yoshinori Takizawa, Takashi Yamatodani, Kiyoshi Misawa, Hiroyuki Mineta
Background: Unexpected multiple primary carcinomas (MPCs) that develop in patients with head and neck carcinomas complicate approaches to their management. We therefore investigated the clinical factors associated with survival outcomes after the treatment of MPCs. Methods: We performed a retrospective review of records of 1104 patients who underwent treatment for primary head and neck carcinoma at Hamamatsu University Hospital. We evaluated clinical staging, age, sex, smoking, alcohol consumption, the primary tumor site (particularly the involvement of the mucosal epithelial lining of the aerodigestive tract), and overall survival (OS) as determined by Kaplan-Meier analysis...
December 13, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29244119/is-social-work-prepared-for-diversity-in-hospice-and-palliative-care
#12
Christine M Rine
The purpose of this article is to assess current and future trends in hospice and palliative care with the objective of informing culturally appropriate best practice for social work. Concern for the intersectionality of racial, ethnic, social, and other differences in end-of-life (EOL) care is imperative given the ever growing range of diversity characteristics among the increasing aging populations in the United States. A review of literature from the current decade that is pertinent to the profession contributes to the ability of social work to consider evidence and build agreement germane to EOL practice settings...
December 13, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29244117/quality-of-life-self-esteem-and-future-expectations-of-adolescent-and-young-adult-cancer-survivors
#13
Kareen N Tonsing, Rosaleen Ow
Significant advancements in treatment modalities over the past few decades have significantly improved the survival rates of many types of childhood cancer, directing attention to the psychosocial consequences of successful treatment and subsequent survival. This study assesses quality of life (QoL) among survivors of childhood cancer. Data were collected by means of a survey questionnaire. Participants were assured of confidentiality and of the voluntary nature of participation. Participants ranged in age from 12 to 24 years (mean age = 17...
December 13, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29244113/t1n0-oesophageal-cancer-patterns-of-care-and-outcomes-over-25-years
#14
Mohamed K Kamel, Benjamin Lee, Mohamed Rahouma, Sebron Harrison, Andrew B Nguyen, Jeffrey L Port, Nasser K Altorki, Brendon M Stiles
OBJECTIVES: Historically, surgical resection has been the mainstay of treatment for T1N0 oesophageal cancer (OC). More recently, oesophageal sparing endoscopic techniques have shown value for local control in a large institutional series. However, the effect of their utilization upon survival rates in large population series is largely unknown. METHODS: The surveillance, epidemiology, and end results (SEER) database was queried for T1N0M0-OC patients (1988-2013)...
December 13, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29244081/atrial-fibrillation-type-matters-greater-infarct-volume-and-worse-neurological-defects-seen-in-acute-cardiogenic-cerebral-embolism-due-to-persistent-or-permanent-rather-than-paroxysmal-atrial-fibrillation
#15
Osamu Inaba, Yasuteru Yamauchi, Masahiro Sekigawa, Naoyuki Miwa, Junji Yamaguchi, Yasutoshi Nagata, Toru Obayashi, Takamichi Miyamoto, Tomoyuki Kamata, Mitsuaki Isobe, Masahiko Goya, Kenzo Hirao
Aims: Some studies have shown that the type of atrial fibrillation (AF), whether paroxysmal AF (PAF) or persistent or permanent AF (PeAF), affects the incidence of ischaemic stroke. This study sought to determine the relationship between the AF pattern and the severity and brain volume of infarction in an AF population including transient ischaemic attack (TIA) patients. Methods and results: This was a retrospective observational study. We studied 161 consecutive patients who were admitted to our stroke care unit with cardiogenic embolism or TIA related to non-valvular AF (age 79 ± 9...
December 12, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29244057/measuring-frailty-in-medicare-data-development-and-validation-of-a-claims-based-frailty-index
#16
Dae Hyun Kim, Sebastian Schneeweiss, Robert J Glynn, Lewis A Lipsitz, Kenneth Rockwood, Jerry Avorn
Background: Frailty is a key determinant of health status and outcomes of health care interventions in older adults that is not readily measured in Medicare data. This study aimed to develop and validate a claims-based frailty index (CFI). Methods: We used data from Medicare Current Beneficiary Survey 2006 (development sample: n = 5,593) and 2011 (validation sample: n = 4,424). A CFI was developed using the 2006 claims data to approximate a survey-based frailty index (SFI) calculated from the 2006 survey data as a reference standard...
December 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29244046/humor-a-rehabilitative-tool-in-the-post-intensive-care-of-young-adults-with-acquired-brain-injury
#17
Kate O'Reilly
PURPOSE: The aim of the study was to describe how paid carers use humor in providing compassionate post-intensive rehabilitation care to young adults with acquired brain injury (ABI) who are unable to perform or direct their own care. DESIGN: This is a qualitative study underpinned by symbolic interactionism. METHODS: Paid carers in a residential aged care facility were interviewed. Interview data were analyzed using grounded theory methods of coding, comparative analysis, memoing, and theoretical sampling...
July 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29243981/assessment-of-intracranial-venous-blood-flow-after-subarachnoid-hemorrhage-a-new-approach-to-diagnose-vasospasm-with-transcranial-color-coded-duplex-sonography
#18
Florian Connolly, Stephan J Schreiber, Christoph Leithner, Georg Bohner, Peter Vajkoczy, José M Valdueza
OBJECTIVE Transcranial color-coded duplex sonography (TCCS) is a reliable tool that is used to assess vasospasm in the M1 segment of the middle cerebral artery (MCA) after subarachnoid hemorrhage (SAH). A distinct increase in blood flow velocity (BFV) is the principal criterion for vasospasm. The MCA/internal carotid artery (ICA) index (Lindegaard Index) is also widely used to distinguish between vasospasm and cerebral hyperperfusion. However, extracranial ultrasonography assessment of the neck vessels might be difficult in an intensive care unit...
December 15, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29243805/interactive-media-as-a-tool-for-reducing-waiting-anxiety-at-paediatric-rehabilitation-hospitals-a-randomized-controlled-trial
#19
Elaine Biddiss, Tara Joy Knibbe, Darcy Fehlings, Patricia Mckeever, Ashley Cohen, Amy Mcpherson
AIM: To investigate the efficacy of waiting room media for reducing anxiety and increasing satisfaction at a paediatric rehabilitation hospital. METHOD: In this clustered, parallel, randomized controlled trial, 310 young people with disabilities (age range 5-19y) and their parents attending outpatient clinics were assigned to interactive media (n=113), a silent nature video (n=97), or media-free comparison (n=100) groups. Young person and parent anxiety was reported using the State-Trait Anxiety Inventory (STAI) on arrival and after 10 minutes in the waiting space...
December 15, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/29243551/donor-leucocytosis-predicts-bacterial-and-fungal-contamination-of-the-preservation-solution-in-visceral-organ-transplantation
#20
Georgios C Sotiropoulos, Jörg Steinmann, Sabrina Stern, Sonia Raduenz, Nikolaos Machairas, Peter M Rath, Fuat H Saner, Andreas Paul, Anja Gallinat
INTRODUCTION: Contamination of the preservation solution may contribute to septic complications that can occur after transplantation and cause higher morbidity and mortality among recipients. The aim of this study was to determine potential donor-related predictors of positive microbiological findings in the preservation solution. DESIGN: We retrospectively studied 16 donor parameters on data from our center for microbiological findings in the preservation solution used in solid-organ recovery...
January 1, 2017: Progress in Transplantation
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