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https://www.readbyqxmd.com/read/28441387/governing-multisectoral-action-for-health-in-low-and-middle-income-countries
#1
Kumanan Rasanathan, Sara Bennett, Vincent Atkins, Robert Beschel, Gabriel Carrasquilla, Jodi Charles, Rajib Dasgupta, Kirk Emerson, Douglas Glandon, Churnrurtai Kanchanachitra, Pete Kingsley, Don Matheson, Rees Murithi Mbabu, Charles Mwansambo, Michael Myers, Jeremias Paul, Thulisile Radebe, James Smith, Orielle Solar, Agnès Soucat, Aloysius Ssennyonjo, Matthias Wismar, Shehla Zaidi
Kumanan Rasanathan and colleagues argue that the potential of multisectoral collaboration for improving health remains untapped in many low- and middle-income countries.
April 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28441085/noun-and-verb-knowledge-in-monolingual-preschool-children-across-17-languages-data-from-cross-linguistic-lexical-tasks-litmus-clt
#2
Ewa Haman, Magdalena Łuniewska, Pernille Hansen, Hanne Gram Simonsen, Shula Chiat, Jovana Bjekić, Agnė Blažienė, Katarzyna Chyl, Ineta Dabašinskienė, Pascale Engel de Abreu, Natalia Gagarina, Anna Gavarró, Gisela Håkansson, Efrat Harel, Elisabeth Holm, Svetlana Kapalková, Sari Kunnari, Chiara Levorato, Josefin Lindgren, Karolina Mieszkowska, Laia Montes Salarich, Anneke Potgieter, Ingeborg Ribu, Natalia Ringblom, Tanja Rinker, Maja Roch, Daniela Slančová, Frenette Southwood, Roberta Tedeschi, Aylin Müge Tuncer, Özlem Ünal-Logacev, Jasmina Vuksanović, Sharon Armon-Lotem
This article investigates the cross-linguistic comparability of the newly developed lexical assessment tool Cross-linguistic Lexical Tasks (LITMUS-CLT). LITMUS-CLT is a part the Language Impairment Testing in Multilingual Settings (LITMUS) battery (Armon-Lotem, de Jong & Meir, 2015). Here we analyse results on receptive and expressive word knowledge tasks for nouns and verbs across 17 languages from eight different language families: Baltic (Lithuanian), Bantu (isiXhosa), Finnic (Finnish), Germanic (Afrikaans, British English, South African English, German, Luxembourgish, Norwegian, Swedish), Romance (Catalan, Italian), Semitic (Hebrew), Slavic (Polish, Serbian, Slovak) and Turkic (Turkish)...
April 25, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28438945/multi-hospital-occurrence-of-pan-resistant-klebsiella-pneumoniae-st147-with-an-isecp1-directed-blaoxa-181-insertion-into-the-mgrb-gene-in-the-united-arab-emirates
#3
Ágnes Sonnevend, Akela Ghazawi, Rayhan Hashmey, Aliasgher Haidermota, Safinaz Girgis, Mubarak Alfaresi, Mohammed Omar, David L Paterson, Hosam M Zowawi, Tibor Pál
The emergence of pan-resistant Klebsiella pneumoniae strains is an increasing concern. In the current study we describe a cluster of 9 pan-resistant K. pneumoniae ST147 isolates encountered in 4 patients over nearly one year in 3 hospitals of the United Arab Emirates. The isolates exhibited highly similar genotypes. All produced chromosomally encoded OXA-181 and the majority also produced the NDM-5 carbapenemase. Similarly to the previously described single isolate from the UAE, MS6671, the mgrB was disrupted by a functional, ISEcp1-driven blaOXA-181 insertion causing resistance to carbapenems...
April 24, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28437804/-prognostic-factors-of-open-abdomen-treatment-in-visceral-surgery
#4
Martin W von Websky, Agnes Jedig, Arnulf Willms, Azin Jafari, Hanno Matthaei, Jörg C Kalff, Steffen Manekeller
Introduction In general surgery, open abdomen treatment (OAT) is used to treat abdominal compartment syndrome (ACS) and sepsis, often after a primary surgical procedure associated with complications. The results achieved in this patient population may depend on factors that are yet unknown. This study evaluates independent patient-related prognostic factors after OAT. Methods 38 clinical parameters and survival data of 165 consecutive general surgery patients after OAT were entered into a prospective database according to a defined algorithm in order to analyse the underlying surgical pathology, predictors of survival and important aspects of OAT-related morbidity...
April 24, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/28437750/becoming-comfortable-with-my-epilepsy-strategies-that-patients-use-in-the-journey-from-diagnosis-to-acceptance-and-disclosure
#5
Sinead Pembroke, Agnes Higgins, Niall Pender, Naomi Elliott
OBJECTIVE: Proponents of resilience theory have highlighted the importance of understanding the processes of resilience. The objective of the study was to explore how people with epilepsy reach a stage of being comfortable with their epilepsy. Identifying the processes used is important to developing effective self-management for people who are newly diagnosed with epilepsy. METHOD: A grounded theory approach involving forty-nine consenting adult people with epilepsy (18 years and over), was used to explore their first-hand experiences of coming to terms with their epilepsy...
April 19, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28437661/ecological-patterns-of-seed-microbiome-diversity-transmission-and-assembly
#6
REVIEW
Ashley Shade, Marie-Agnès Jacques, Matthieu Barret
Seeds are involved in the transmission of microorganisms from one plant generation to another and consequently act as the initial inoculum for the plant microbiota. The purpose of this mini-review is to provide an overview of current knowledge on the diversity, structure and role of the seed microbiota. The relative importance of the mode of transmission (vertical vs horizontal) of the microbial entities composing the seed microbiota as well as the potential connections existing between seed and other plant habitats such as the anthosphere and the spermosphere is discussed...
April 21, 2017: Current Opinion in Microbiology
https://www.readbyqxmd.com/read/28437113/development-and-application-of-a-recyclable-high-load-magnetic-co-c-hybrid-romp-derived-benzenesulfonyl-chloride-reagent-and-utility-of-corresponding-analogues
#7
Saqib Faisal, Qin Zang, Pradip K Maity, Agnes Brandhofer, Patrick C Kearney, Oliver Reiser, Robert N Grass, Diana Stoianova, Paul R Hanson
The development and application of high-load, recyclable magnetic Co/C hybrid ROMP-derived benzenesulfonyl chloride and analogues is reported. The regeneration and utility of these reagents in the methylation/alkylation of various carboxylic acids is demonstrated via efficient retrieval of the magnetic reagent with a neodymium magnet. Additional reactions employing the analogue sulfonic acid and in situ generated magnetic benzenesulfonyl azide are also reported.
April 24, 2017: Organic Letters
https://www.readbyqxmd.com/read/28434993/effect-of-rat-spinal-cord-injury-hemisection-on-the-ex-vivo-uptake-and-release-of-3-h-noradrenaline-from-a-slice-preparation
#8
Zoltán Borbély, Benedek Krisztián Csomó, Ágnes Kittel, Gábor Gerber, Gábor Varga, E Sylvester Vizi
We measured the ex vivo uptake and release of [(3)H]noradrenaline ([(3)H]NA) from perfused rat spinal cord slice preparations at 1, 3 and 14 days after unilateral hemisection-induced spinal cord injury (SCI) compared with control slice preparations. After surgical hemisection under anaesthesia, the rats showed characteristic signs of hemiplegia, with no movement of the ipsilateral hindlimb. After 3 days, the electron microscopy images showed overall degeneration of neuronal organelles and the myelin sheath, but the synapses seemed to be intact...
April 20, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28434948/international-and-multidisciplinary-expert-recommendations-for-the-use-of-biologics-in-systemic-lupus-erythematosus
#9
REVIEW
Jean-François Kleinmann, Florence Tubach, Véronique Le Guern, Alexis Mathian, Christophe Richez, David Saadoun, Karim Sacre, Jérémie Sellam, Raphaèle Seror, Zahir Amoura, Emmanuel Andres, Sylvain Audia, Brigitte Bader-Meunier, Gilles Blaison, Bernard Bonnotte, Patrice Cacoub, Sophie Caillard, Laurent Chiche, Olivier Chosidow, Nathalie Costedoat-Chalumeau, Claire Daien, Eric Daugas, Nairouz Derdèche, Andrea Doria, Olivier Fain, Fadi Fakhouri, Dominique Farge, Cem Gabay, Sylvie Guillo, Eric Hachulla, Najia Hajjaj-Hassouni, Mohamed Hamidou, Frédéric A Houssiau, Noémie Jourde-Chiche, Isabelle Koné-Paut, Aïcha Ladjouz-Rezig, Olivier Lambotte, Dan Lipsker, Xavier Mariette, Nicolas Martin-Silva, Thierry Martin, François Maurier, Roderich Meckenstock, Arsène Mékinian, Olivier Meyer, Shirine Mohamed, Jacques Morel, Bruno Moulin, Denis Mulleman, Thomas Papo, Vincent Poindron, Xavier Puéchal, Leonardo Punzi, Pierre Quartier, Laurent Sailler, Amar Smail, Martin Soubrier, Agnès Sparsa, Zoubida Tazi-Mezalek, Leith Zakraoui, Stéphane Zuily, Jean Sibilia, Jacques-Eric Gottenberg
BACKGROUND/PURPOSE: Despite conventional immunosuppressants, active and steroid-dependent systemic lupus erythematosus (SLE) represents a therapeutic challenge. Only one biologic, belimumab, has been approved, but other biologics are sometimes used off-label. Given the lack of evidence-based data in some clinical situations encountered in real life, we developed expert recommendations for the use of biologics for SLE. METHODS: The recommendations were developed by a formal consensus method...
April 18, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/28434650/global-kidney-health-2017-and-beyond-a-roadmap-for-closing-gaps-in-care-research-and-policy
#10
REVIEW
Adeera Levin, Marcello Tonelli, Joseph Bonventre, Josef Coresh, Jo-Ann Donner, Agnes B Fogo, Caroline S Fox, Ron T Gansevoort, Hiddo J L Heerspink, Meg Jardine, Bertram Kasiske, Anna Köttgen, Matthias Kretzler, Andrew S Levey, Valerie A Luyckx, Ravindra Mehta, Orson Moe, Gregorio Obrador, Neesh Pannu, Chirag R Parikh, Vlado Perkovic, Carol Pollock, Peter Stenvinkel, Katherine R Tuttle, David C Wheeler, Kai-Uwe Eckardt
The global nephrology community recognises the need for a cohesive plan to address the problem of chronic kidney disease (CKD). In July, 2016, the International Society of Nephrology hosted a CKD summit of more than 85 people with diverse expertise and professional backgrounds from around the globe. The purpose was to identify and prioritise key activities for the next 5-10 years in the domains of clinical care, research, and advocacy and to create an action plan and performance framework based on ten themes: strengthen CKD surveillance; tackle major risk factors for CKD; reduce acute kidney injury-a special risk factor for CKD; enhance understanding of the genetic causes of CKD; establish better diagnostic methods in CKD; improve understanding of the natural course of CKD; assess and implement established treatment options in patients with CKD; improve management of symptoms and complications of CKD; develop novel therapeutic interventions to slow CKD progression and reduce CKD complications; and increase the quantity and quality of clinical trials in CKD...
April 20, 2017: Lancet
https://www.readbyqxmd.com/read/28434527/ajkd-atlas-of-renal-pathology-kidney-transplant-interstitial-fibrosis-tubular-atrophy
#11
Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
May 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28434526/ajkd-atlas-of-renal-pathology-calcineurin-inhibitor%C3%A2-nephrotoxicity
#12
Mark A Lusco, Agnes B Fogo, Behzad Najafian, Charles E Alpers
No abstract text is available yet for this article.
May 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28431338/the-design-and-fabrication-of-beta-sensor-system-for-in-situ-diffusion-tests-in-mudstone-in-france
#13
Zhenhua Lin, Olivier Tillement, Marie-Genevieve Blanchin, Vivek Jindal, Agnès Vinsot, Romain V H Dagnelie, Virginie Blin, Yanick Lettry, Benoit Hautefeuille
Long term in situ diffusion experiments in the Callovian-Oxfordian mudstone (France) are designed in the context of nuclear waste management. β-emitters HTO and (36)Cl radiotracers are representative of neutral and anionic species in these experiments. Studies have been carried out to design an in situ beta monitoring system in order to quantify tracer migration in the rock pore water over time. The development, design and calibration of β-emitter radiation sensors were performed. An optimised geometry was calculated for the detection chamber of (36)Cl in solution (Ø×L=30×2mm(2)) via Monte-Carlo N-Particle transport simulation tools...
April 1, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28429471/formation-of-silver-nanoparticles-by-electron-transfer-in-peptides-and-c-cytochromes
#14
Serhii I Vasylevskyi, Sonja Kracht, Paula Corcosa, Katharina M Fromm, Bernd Giese, Michael Füeg
The reduction of Ag(+) ions to Ag(0) atoms is a highly endergonic reaction step, only the aggregation to Agn clusters leads to an exergonic process. These elementary chemical reactions play a decisive role if Ag nanoparticles (AgNPs) are generated by electron transfer (ET) reactions to Ag(+) ions. We studied the formation of AgNPs in peptides by photoinduced ET, and in c-cytochromes by ET from their Fe(2+) /hemes. Our earlier photoinduced experiments in peptides had demonstrated that histidine prevents AgNP formation...
April 21, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28429382/technical-note-direct-measurement-of-clinical-mammographic-x-ray-spectra-using-a-cdte-spectrometer
#15
Josilene C Santos, Alessandra Tomal, Tânia A Furquim, Agnes M F Fausto, Maria S Nogueira, Paulo R Costa
PURPOSE: To introduce and evaluate a method developed for the direct measurement of mammographic x-ray spectra using a CdTe spectrometer. The assembly of a positioning system and the design of a simple and customized alignment device for this application is described. METHODS: A positioning system was developed to easily and accurately locate the CdTe detector in the x-ray beam. Additionally, an alignment device to line up the detector with the central axis of the radiation beam was designed...
April 21, 2017: Medical Physics
https://www.readbyqxmd.com/read/28428010/a-strategy-of-faster-movements-used-by-elderly-humans-to-lift-objects-of-increasing-weight-in-ecological-context
#16
Thomas Hoellinger, Joseph McIntyre, Lena Jami, Sylvain Hanneton, Guy Cheron, Agnes Roby-Brami
It is not known whether, during the course of ageing, changes occur in the motor strategies used by the CNS for lifting objects of different weights. Here, we analysed the kinematics of object-lifting in two different healthy groups (young and elderly people) plus one well known deafferented patient (GL). The task was to reach and lift onto a shelf an opaque cylindrical object with changing weight. The movements of the hand and object were recorded with electromagnetic sensors. In an ecological context (i.e...
April 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28426846/affordability-of-cancer-drugs-in-sub-saharan-africa-effects-of-pricing-on-needless-loss-of-life
#17
Yehoda M Martei, Agnes Binagwaho, Lawrence N Shulman
No abstract text is available yet for this article.
April 20, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28426812/religion-and-the-public-ethics-of-stem-cell-research-attitudes-in-europe-canada-and-the-united-states
#18
Nick Allum, Agnes Allansdottir, George Gaskell, Jürgen Hampel, Jonathan Jackson, Andreea Moldovan, Susanna Priest, Sally Stares, Paul Stoneman
We examine international public opinion towards stem-cell research during the period when the issue was at its most contentious. We draw upon representative sample surveys in Europe and North America, fielded in 2005 and find that the majority of people in Europe, Canada and the United States supported stem-cell research, providing it was tightly regulated, but that there were key differences between the geographical regions in the relative importance of different types of ethical position. In the U.S., moral acceptability was more influential as a driver of support for stem-cell research; in Europe the perceived benefit to society carried more weight; and in Canada the two were almost equally important...
2017: PloS One
https://www.readbyqxmd.com/read/28426205/euro-6-unregulated-pollutant-characterization-and-statistical-analysis-of-aftertreatment-device-and-driving-condition-impact-on-recent-passenger-car-emissions
#19
Simon Martinet, Yao Liu, Cédric Louis, Patrick Tassel, Pascal Perret, Agnès Chaumond, Michel Andre
This study aims to measure and analyze unregulated compound emissions for two Euro 6 diesel and gasoline vehicles. The vehicles were tested on a chassis dynamometer under various driving cycles: Artemis driving cycles (urban, road and motorway), the New European Driving Cycle (NEDC) and the World Harmonized Light-Duty Test Cycle (WLTC) for Europe, and world approval cycles. The emissions of unregulated compounds - such as total particle number (PN) (over 5.6 nm), black carbon (BC), NO2, BTEX (benzene, toluene, ethylbenzene and xylene), carbonyl compounds and polycyclic aromatic hydrocarbons (PAHs) - were measured with several on-line devices and different samples were collected using cartridges and quartz filters...
April 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28424760/insights-into-local-tumor-microenvironment-immune-factors-associated-with-regression-of-cutaneous-melanoma-metastases-by-mycobacterium-bovis-bacille-calmette-gu%C3%A3-rin
#20
Junbao Yang, Maris S Jones, Romela Irene Ramos, Alfred A Chan, Agnes F Lee, Leland J Foshag, Peter A Sieling, Mark B Faries, Delphine J Lee
Mycobacterium bovis bacille Calmette-Guérin (BCG) is listed as an intralesional (IL) therapeutic option for inoperable stage III in-transit melanoma in the National Comprehensive Cancer Network Guidelines. Although the mechanism is unknown, others have reported up to 50% regression of injected lesions, and 17% regression of uninjected lesions in immunocompetent patients after direct injection of BCG into metastatic melanoma lesions in the skin. BCG and other mycobacteria express ligands capable of stimulating the γ9δ2 T cells...
2017: Frontiers in Oncology
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