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https://www.readbyqxmd.com/read/29333009/peripheral-and-central-giant-cell-lesions-in-children-institutional-experience-at-subharti-dental-college-and-hospital
#1
Preetika Chandna, Nikhil Srivastava, Vishal Bansal, Vijay Wadhwan, Prajesh Dubey
Introduction: Giant cell lesions (GCG) are a group of varied lesions that contain a multitude of multinucleated, osteoclast like giant cells within connective tissue stroma. These include giant cell granulomas which may be central (CGCG), if they lie within the jaw bone, or, peripheral (PGCG) if they lie within the soft tissue. Giant cell granulomas comprised 9.29% of all oral lesions. This case series comprises of 5 giant cell lesions in children between the ages of 4 to 12 years. Materials and Methods: A retrospective analysis was conducted of all patients who were diagnosed with giant cell lesions and treated over a period of 10 years (from August 2004 to August 2014) at Subharti Dental College and Hospital, Meerut, India...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29330978/intramuscular-diclofenac-vs-periprostatic-lidocaine-injection-for-controlling-pain-undergoing-transrectal-ultrasound-guided-prostatic-biopsy
#2
Syed Iftikhar Alam, Hazratullah, Zeeshan Kibria, Iqra Masood, Rubab Jawed
BACKGROUND: Transrectal ultrasound (TRUS) technique for getting prostatic tissue for histopathology is now the standard procedure for malignant lesions of the prostate and imperative diagnostic investigation of patients with clinical specks of prostatic neoplasia. During TRUS guided biopsy, pain control has been important issue therefore, highly potent analgesia before this procedure should be considered on high priority according to current census. Therefore, we compared intramuscular diclofenac injection with sensory blockade of injection lidocaine to abolish pain undergoing prostatic biopsy with TRUS technique...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29325851/microbial-population-changes-in-patients-with-medication-related-osteonecrosis-of-the-jaw-treated-with-systemic-antibiotics
#3
Lieselotte De Bruyn, Ruxandra Coropciuc, Wim Coucke, Constantinus Politis
OBJECTIVE: This study aimed to investigate the bacterial population in patients with medication-related osteonecrosis of the jaw (MRONJ) after treatment with doxycycline and metronidazole. STUDY DESIGN: A total of 38 patients with MRONJ (age range 55-88, mean age 73 + 8.82 standard deviation) treated with doxycycline first and with metronidazole second were enrolled in this study. Two swabs were taken at the margin of the infected MRONJ lesion after applying pressure on the marginal mucosa, and visible pus was secreted...
December 11, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29322252/-cystic-lesions-of-the-jaws
#4
D Baumhoer, S Höller
Cystic lesions of the jaws comprise a spectrum of inflammatory, developmental and neoplastic changes that can clinically appear strikingly similar. Squamous cell metaplasia due to superinfection can further blur the histologic hallmarks of the individual lesions. In this article an overview of the most important differential diagnoses and the novelties of the latest World Health Organisation (WHO) classification on head and neck tumours released in early 2017 is provided. In contrast to the previous edition, odontogenic cysts have been re-introduced and several changes in terminology and taxonomy have been complemented...
January 10, 2018: Der Pathologe
https://www.readbyqxmd.com/read/29311424/jaw-bones-regeneration-using-mesenchymal-stem-cells-a-single-center-experience
#5
Walter Colangeli, Umberto Riccelli, Amerigo Giudice, Ida Barca, Davide Caruso, Daniela Novembre, Claudio Tortosa, Raffaella Cordaro, Maria Giulia Cristofaro
PURPOSE: Mesenchymal stem cells (MSC), which are multipotent stromal cells, are considered to be a promising resource in tissue engineering and tissue regeneration. MSCs have been used to generate new maxillary bone with clinically successful results. The aim of this study was to determine the role of MSC in bone regeneration procedures in patients with benign maxillary lesions. METHODS: A study was conducted on five patients treated for maxillary bone defects resulting from biopsy of benign lesions at the University Hospital of Magna Græcia, Catanzaro, Italy from January 2015 to October 2016...
December 21, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29303131/benign-tumors-and-tumor-like-lesions-of-the-oral-cavity-and-jaws-an-analysis-of-709-cases
#6
A Kilinc, N Saruhan, B Gundogdu, E Yalcin, U Ertas, G Urvasizoglu
PURPOSE: The purpose was to examine the prevalence, gender, age and site(s) of odontogenic and nonodontogenic benign tumors, and tumor-like lesions occurring in the oral cavity and jaws in a Turkish population, particularly, in the Eastern Turkey, and to compare findings of this study with other reports. MATERIALS AND METHODS: The data were collected from the files of the Department of Oral and Maxillofacial Surgery and the Department of Oral Pathology, Ataturk University, Turkey, during a 10-year period from January 2005 to January 2015...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29298784/conservative-management-of-keratocystic-odontogenic-tumour-in-a-young-child-with-decompression-and-an-intraoral-appliance-5-year-follow-up
#7
Rahul Morankar, Sarabjot K Bhatia, Ashima Goyal, Pramod Gulia
Keratocystic odontogenic tumour (KCOT) is considered one of the most aggressive odontogenic lesions presenting high recurrence rate which varies according to treatment modalities employed for management. The treatment rendered should have a lowest possible risk of recurrence and least morbidity while still eradicating the lesion. Although the radical treatment options like enucleation and en bloc resection are associated with lesser recurrences, these can lead to greater morbidity, especially in children with developing teeth and jaw bones, thus, emphasising need to consider more conservative treatment options like decompression and marsupialisation...
January 3, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29289789/zoledronic-acid-increases-the-prevalence-of-medication-related-osteonecrosis-of-the-jaw-in-a-dose-dependent-manner-in-rice-rats-oryzomys-palustris-with-localized-periodontitis
#8
J G Messer, J L Mendieta Calle, J M Jiron, E J Castillo, C Van Poznak, N Bhattacharyya, D B Kimmel, J I Aguirre
OBJECTIVE: Investigate role of dose/duration of zoledronic acid (ZOL), a powerful anti-resorptive (pAR), on prevalence of medication-related osteonecrosis of the jaw (MRONJ) in rice rats (Oryzomys palustris), a species with natural susceptibility to food impaction-induced localized periodontitis (FILP). We hypothesize that ZOL induces MRONJ lesions in rice rats with FILP, and that the prevalence of MRONJ rises with increasing dose and duration of ZOL treatment. METHODS: We performed a toxicology experiment with clinically-relevant doses of ZOL in female rats (N=230) fed standard (STD) rodent chow...
December 28, 2017: Bone
https://www.readbyqxmd.com/read/29287708/intratarsal-keratinous-eyelid-cysts-in-gorlin-syndrome-a-review-and-reappraisal
#9
REVIEW
Natalie Wolkow, Frederick A Jakobiec, Michael K Yoon
A 38-year-old woman presented with multiple bilateral recurrent eyelid cysts. Her medical history was notable for Gorlin (nevoid basal cell carcinoma) syndrome. Histopathologic and immunohistochemical examinations revealed that the lesions were intratarsal keratinous cysts. They were similar in appearance to sporadic intratarsal keratinous cysts and closely resembled odontogenic keratocysts of the jaw. Eyelid cysts occur in up to 40 percent of patients with Gorlin syndrome; however, their description has been cursory and for the most part, outside of the ophthalmic literature...
December 26, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29284928/molecular-pathogenesis-and-diagnostic-imaging-of-metastatic-jaw-tumors
#10
REVIEW
Kenniyan Kumar Srichinthu, Arjun Parameshwar Raveendran, Periyasamy Tamilthangam, Joseph Joe, Charanya Duraisamy, Thukanayakanpalayam Ragunathan Yoithapprabhunath, Chitturi Ravi Teja
Metastasis is the spread of malignant cells from a primary tumor to distant sites through lymphatics or blood vessels. Malignant lesions metastasizing to the oral and perioral region are a rarity indeed. Malignant lesions could metastasize to both soft tissue of oral cavity and the hard tissues of the jaws and recent meta-analysis showed that metastasis is more common in the jaws than oral soft tissues because of rich vascular supply. The incidence is very low when compared to the incidence of primary oral cancers; nevertheless, one has to include in the diagnostic workup, metastatic malignant lesions, when an irregular ill-defined radiolucency or radiodensity with ragged edges in noted...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29284472/differentiating-early-stage-florid-osseous-dysplasia-from-periapical-endodontic-lesions-a-radiological-based-diagnostic-algorithm
#11
Victor Daviet-Noual, Anne-Laure Ejeil, Charles Gossiome, Nathan Moreau, Benjamin Salmon
BACKGROUND: Osseous dysplasia (OD) is the most common fibro-osseous lesion of the jaw affecting the periapical region. Early stages of OD can resemble periapical radiolucencies, thus mimicking the radiological aspects of an endodontic pathology. Such radiolucent lesions affecting previously decayed or treated teeth are even more complex to interpret. CASE PRESENTATION: The aim of this paper is to report a case-series of representative clinical situations describing the radiological features and illustrating the diagnostic workup of patients with florid osseous dysplasia (FOD)...
December 28, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29283937/piezosurgery-for-treatment-of-large-recurrent-mandibular-osteoma
#12
Josué Hernando, Antonio Aguilar-Salvatierra, Ignacio Osoitz Leizaola-Cardesa, Pedro Martínez Seijas, Pablo Aguirre-Echebarria, Javier Martín, Gerardo Gómez-Moreno
BACKGROUND: Osteomas are infrequent benign bone tumors of uncertain etiology. They are usually situated at extremities and their occurrence in the jaws is relatively rare. There are 3 types of osteoma: central, peripheral, and extraskeletal. Preoperative presumptive diagnosis is performed by means of radiography using orthopantomographs, computerized tomographs, or cone beam scans. Treatment is surgical and consists of careful exeresis and curettage of the adjacent tissue. In recent years, piezoelectric surgery has been used to treat bone pathologies in the maxillofacial area, orthopedic surgery, and neurosurgery...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29279825/ct-evaluation-of-underlying-bone-sclerosis-in-patients-with-oral-squamous-cell-carcinoma-a-preliminary-retrospective-study
#13
Gyu-Dong Jo, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee, Soon-Chul Choi, Kyung-Hoe Huh
Purpose: Underlying bone sclerosis is frequently observed in clinical settings when oral squamous cell carcinoma (OSCC) invades the jaw bone. The aim of this study was to assess the prevalence and characteristics of underlying bone sclerosis in patients with OSCC. Materials and Methods: We retrospectively reviewed the computed tomographic (CT) images of 131 patients who underwent mandibulectomy between January 2012 and December 2015 to treat OSCC. The presence, degree, and extent of underlying bone sclerosis were assessed on CT images and correlated with the following imaging patterns of bone invasion: cortical invasion, medullary invasion with a smooth margin, and medullary invasion with an irregular margin...
December 2017: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/29260762/-radiographic-manifestations-variants-of-odontogenic-inflammatory-destructive-lesions-in-lower-molars
#14
A G Nadtochiy, V A Semkin, A P Arzhantsev, P A Kolotikov
The analysis and comparison of clinical and radiographic manifestations of odontogenic destructive processes in the area of molars of the lower jaw 54 patients, treated at the outpatient department of surgical dentistry CRID and MS. Set the main features of clinical manifestations depending on the distribution of the destructive process of the bone.
2017: Stomatologii︠a︡
https://www.readbyqxmd.com/read/29251459/phosphate-buffer-stabilized-0-1-chlorine-dioxide-oral-rinse-for-managing-medication-related-osteonecrosis-of-the-jaw
#15
REVIEW
Srinivas Rao Myneni Venkatasatya, Howard H Wang, Swetha Alluri, Sebastian G Ciancio
PURPOSE: This is a review of the literature on nonsurgical treatment of non-healing medication related osteonecrosis of the jaw (MRONJ) utilizing a phosphate buffer-stabilized 0.1% chlorine dioxide mouthrinse. METHODS: A literature search in PubMed revealed only six case reports. MRONJ lesion site description, patient's medication history, the healing time, and the MRONJ treatment protocol followed by those authors were recorded. Additional literature review of the scientific mechanism, risks and benefits, safety and efficacy of the phosphate buffer-stabilized 0...
December 2017: American Journal of Dentistry
https://www.readbyqxmd.com/read/29247621/peripheral-ameloblastoma-a-study-of-18-cases-and-usage-of-ber-ep4-immunohistochemistry-to-rule-out-a-diagnosis-of-intraoral-basal-cell-carcinoma
#16
Jasbir D Upadhyaya, Indraneel Bhattacharyya, Sarah G Fitzpatrick, Donald M Cohen, Mohammed N Islam
PURPOSE: Peripheral ameloblastoma (PA) is a rare odontogenic tumor arising in the mucosa of tooth-bearing areas of the jaws that typically shows no radiographic evidence of bone involvement. It bears close histologic resemblance to intraoral basal cell carcinoma (IOBCC), an extremely rare entity. In our experience from previous published data, 3 cases of IOBCC were initially misdiagnosed as PA and were later differentiated from PA on the basis of Ber-EP4 protein expression. This unusual but significant experience set the premise for us to rule out a diagnosis of IOBCC by evaluating Ber-EP4 expression in all previously diagnosed cases of PA from the University of Florida Oral Pathology (UFOP) biopsy service archives...
November 23, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29243681/conservative-management-of-large-mandibular-dentigerous-cysts-with-a-novel-approach-for-follow-up-two-case-reports
#17
Ieva Gendviliene, Paul Legrand, Laura Ferreira Pinheiro Nicolielo, Deepti Sinha, Yannick Spaey, Constantinus Politis, Reinhilde Jacobs
BACKGROUND: Dentigerous cysts are odontogenic cysts of the jaws accounting for approximately 24% of all epithelium-lined jaw cysts. Rarely, these cysts can become extremely large causing additional symptoms, while challenging treatment. This article represents a novel approach for radiological treatment follow up of large dentigerous cysts. MATERIAL AND METHODS: Dentigerous cysts were treated by marsupialization, using dedicated obturators and enucleation of the cyst afterwards...
2017: Stomatologija
https://www.readbyqxmd.com/read/29242956/-odontogenic-tumours-and-bone-tumours-of-the-jaw-changes-in-the-new-who-classification
#18
REVIEW
D Baumhoer
At the beginning of 2017, the fourth edition of the WHO Classification of Head and Neck Tumours was published, 12 years after the previous version. Notably, various changes introduced in the third edition have been revised so in some aspects the current classification has more similarities to the second edition of 1992 than to the third edition. A central goal of the editors was to create a classification that can be used worldwide. Molecular findings have therefore been included and updated but are not mandatory for establishing a diagnosis...
December 14, 2017: Der Pathologe
https://www.readbyqxmd.com/read/29239035/heritable-forms-of-primary-hyperparathyroidism-a-current-perspective
#19
REVIEW
Ronald A DeLellis, Shamlal Mangray
Primary hyperparathyroidism (PHPT) is one of the most common of all endocrine disorders encountered by the practising histopathologist. The vast majority of lesions are sporadic in nature, approximately 85% of which are parathyroid adenomas, while hyperplasia and carcinoma account for 10-15% and fewer than 1%, of cases, respectively. Heritable forms of PHPT are much less common and present challenges both to clinicians and pathologists, particularly when they are the presenting feature of an endocrine syndrome...
January 2018: Histopathology
https://www.readbyqxmd.com/read/29233700/volumetric-analysis-of-keratocystic-odontogenic-tumors-and-non-neoplastic-jaw-cysts-comparison-and-its-clinical-relevance
#20
Martin Kauke, Ali-Farid Safi, Andrea Grandoch, Hans-Joachim Nickenig, Joachim Zöller, Matthias Kreppel
The keratocystic odontogenic tumor (KCOT) is capable of causing vast osseous destruction. Histopathological examination is pivotal for diagnosis. The diagnostic process can sometimes be hindered by tissue inflammation of KCOTs with loss of defining criteria, resulting in misdiagnosis as an odontogenic jaw cyst. We discuss the possible merits of volumetric analysis when facing this particular diagnostic dilemma and for pathophysiological characterization of KCOTs. We included 114 patients, of whom 27 were histopathologically diagnosed with a KCOT and 87 with dentigerous (n = 41) and periapical cyst (n = 46)...
November 21, 2017: Journal of Cranio-maxillo-facial Surgery
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