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Fibrous dysplasia maxillofacial

G N Mainville, D P Turgeon, A Kauzman
Benign fibro-osseous lesions of the maxillofacial skeleton constitute a heterogeneous group of disorders that includes developmental, reactive (dysplastic) and neoplastic lesions. Although their classification has been reviewed multiple times in the past, the most common benign fibro-osseous lesions are fibrous dysplasia, osseous dysplasia and ossifying fibroma. For the dental clinician, the challenges involve diagnosis and treatment (or lack thereof). A careful correlation of all clinical, radiologic and microscopic features is essential to establish a proper diagnosis and a clear treatment plan...
July 7, 2016: Oral Diseases
Peter Markov, Ali Zakir Syed, Christiana Markova, Rui Amaral Mendes
A 30-year-old woman presented for orthodontic treatment, with a chief symptom of a 'shifting bite' and concurrent facial asymmetry with aesthetic concerns. The patient had previously received treatment from several general dentists and several specialists, without accurate diagnosis. Radiological investigation coupled with biopsy confirmed a diagnosis of fibrous dysplasia. Proper diagnosis led to changes in the treatment plan and gave the patient realistic expectations about the options she had for the outcome of treatment...
2016: BMJ Case Reports
Jianwei Pan, Bin Ye, Jing Hu, Xiang Li, Yiqun Zhang, Jihua Li
Facial asymmetry deformity is the most common symptom of patients with fibrous dysplasia. This study provides a novel method based on computed tomography scan data, mirror-imaged reverse engineering and rapid prototyping for design and manufacture of an individual template guiding accurately the extent and quantity of partial resection of hyperplastic tissues to reshape the affected bones during operation. Ten adult patients with unilateral facial fibrous dysplasia accepted these treatments, the postoperative appearances showed that the protrusions were effectively reduced; bilateral faces were basically symmetric with no serious complications...
March 2016: Journal of Craniofacial Surgery
Shuiting Fu, Zhuowei Tian, Chenping Zhang, Yue He
Mazabraud's syndrome (MS) is a rare disease that is a combination of fibrous dysplasia and intramuscular myxomas. MS is a benign lesion and there is little data on the disease due to its low incidence. In the present study, the case of a 38-year-old patient who presented with a soft-tissue mass involving the masseter and swelling at the mandibular body and mandibular ramus is reported. Since the mandible is an important aesthetic and functional organ in the oral and maxillofacial region, surgery was primarily aimed at resecting the tumor, with good safety margins, and reconstructing the resultant defect...
November 2015: Oncology Letters
Sevtap Akbulut, Mehmet Gokhan Demir, Kayhan Basak, Mustafa Paksoy
OBJECTIVES: Osseous dysplasias are the most common subtype of fibro-osseous lesions of the maxillofacial bones. They are benign and often present as incidental asymptomatic lesions. Diagnosis can be made with clinical and radiographic examination. CASE REPORT: This article reports the case of a 47-year-old man with a huge cementifying osseous dysplasia of the maxilla that presented with secondary infection after teeth extraction and repair of oroantral fistula. A subtotal maxillectomy had to be done after conservative treatment failed to resolve the infection...
2015: Acta Medica (Hradec Králové)
Mirna S Cordeiro, André R Backes, Antônio F Durighetto Júnior, Elmar H G Gonçalves, Jefferson X de Oliveira
Fibrous dysplasia (FD) is a developmental anomaly in which the normal medullary space of the affected bone is replaced by fibro-osseous tissue. This condition is typically encountered in adolescents and young adults. It affects the maxillofacial region and it can often cause severe deformity and asymmetry. Therefore, accurate diagnosis is critical to determine the appropriate treatment of each case. In this sense, computed tomography (CT) is a relevant resource among the imaging techniques for correct diagnosis of this condition...
February 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Prashanti Eachempati, Himanshi Aggarwal, Vidya Shenoy, Mohan Baliga
Fibrous dysplasia is a non-neoplastic hamartomatous developmental fibro-osseous lesion of bone. Monostotic fibrous dysplasia is more common than the polyostotic form and usually involves jaw bones, ribs and femur. Maxillary lesions may extend to involve the maxillary sinus, zygoma, sphenoid bone and floor of the orbit and require surgical intervention resulting in an acquired defect of the involved site. A multidisciplinary team approach involving an oral pathologist, oral surgeon, oral medicine expert and maxillofacial prosthodontist is required for successful treatment and rehabilitation of such patients...
2015: BMJ Case Reports
Alastair Darwood, Jonathan Collier, Naresh Joshi, William E Grant, Veronique Sauret-Jackson, Robin Richards, Andrew Dawood, Niall Kirkpatrick
Rapid prototyped or three dimensional printed (3D printed) patient specific guides are of great use in many craniofacial and maxillofacial procedures and are extensively described in the literature. These guides are relatively easy to produce and cost effective. However existing designs are limited in that they are unable to be used in procedures requiring the 3D contouring of patient tissues. This paper presents a novel design and approach for the use of three dimensional printing in the production of a patient specific guide capable of fully guiding intraoperative 3D tissue contouring based on a pre-operative plan...
September 2015: Journal of Cranio-maxillo-facial Surgery
Shang-Hui Zhou, Wen-Jun Yang, Sheng-Wen Liu, Jiang Li, Chun-Ye Zhang, Yun Zhu, Chen-Ping Zhang
Fibrous dysplasia (FD) as an abnormal bone growth is one of the common fibro-osseous leasions (FOL) in oral and maxillofacial region, however, its etiology still remains unclear. Here, we performed gene expression profiling of FD using microarray analysis to explore the key molecule events in FD development, and develop potential diagnostic markers or therapeutic targets for FD. We found that 1,881 genes exhibited differential expression with more than two-fold changes in FD compared to normal bone tissues, including 1,200 upregulated genes and 681 downregulated genes...
2014: International Journal of Clinical and Experimental Pathology
Y Wang, G Sun, M Lu, Q Hu
Fibrous dysplasia is a benign and slowly progressive disorder of bone in which normal cancellous bone is replaced by immature woven bone and fibrous tissue. Precise excision of the lesion is crucial to restore function and aesthetics. We present our experience using surgical navigation technology for the recontouring of the faces of 8 patients with maxillofacial fibrous dysplasia who were treated from 2012-2013, all of whom were thought suitable for surgical recontouring. Preoperative computed tomography (CT) scans were used to make a virtual plan based on the patient's mirrored anatomy...
April 2015: British Journal of Oral & Maxillofacial Surgery
Mark E Peacock, Ranjitha Krishna, J Wylie Gustin, Mark R Stevens, Roger M Arce, Rafik A Abdelsayed
OBJECTIVE: The goal of this study was to reveal clinical and pathologic findings on idiopathic bone cavity lesions (IBC). STUDY DESIGN: A retrospective analysis of 20 IBC cases diagnosed from 2004 to 2014 from a university-based maxillofacial pathology service was performed and included all pertinent clinical, histologic, and radiographic findings. RESULTS: Eleven women (age = 36 ± 12.7) and 9 men (age = 23 ± 17.9) diagnosed with IBC were selected for analysis...
April 2015: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
D S MacDonald
During the last decade much has changed in our understanding of fibro-osseous lesions (FOLs) of the jaws with regards to their imaging, their nomenclature and classification, and their potential impact on the overall health of the patient. The changes in nomenclature, classification, and the FOLs' potential association with important syndromes are discussed with the assistance of a flowchart. The lesions, fibrous dysplasia (FD), ossifying fibroma (OF), and osseous dysplasia (OD), though with similar histopathology, have very different clinical and radiological presentations, behaviour, and treatment outcomes...
January 2015: Clinical Radiology
Xin-ying Tan, Min Hu, Ye Tao, Jin-chao Luo, Juan Xu, San-xia Liu
PURPOSE: To evaluate the effect of computer-aided surgical techniques in surgical treatment of cranio-maxillofacial fibrous dysplasia. METHODS: Twenty-two patients from January 1999 to December 2012 with cranio-maxillofacial fibrous dysplasia were treated in our department. According to the patients' specific conditions, surgeons designed surgical programs, and used computer-assisted surgical techniques to produce skull model and navigation template individually...
February 2014: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
L M Muwazi, A Kamulegeya
BACKGROUND: Fibro-osseous lesions of the jaws are a diagnostic challenge for the pathologist because histologically, they are not easily distinguishable. African data on the prevalence of these lesions are scarce. We present a 5-year report of benign fibro-osseous lesions at Mulago Hospital, Uganda, showing the frequency and distribution of these lesions. MATERIALS AND METHODS: Confirmed fibro-osseous lesions reports at the pathology department (2007-2012) were retrieved...
January 2015: Oral Diseases
Victoria L Woo, Jessica Pharar, Edward E Herschaft, Cody C Hughes, Harvey A Akerson, Robert A Danforth
No abstract text is available yet for this article.
March 2014: Journal of the American Dental Association
Massimo Fusconi, Michela Conte, Martina Pagliarella, Chiara De Vincentiis, Armando De Virgilio, Anna Teresa Benincasa, Simone Alessi, Andrea Gallo
Objective Fibrous dysplasia (FD) is a benign bone disorder in facial bones. This study evaluates the possibility of diagnosing fibrous dysplasia on imaging alone, without biopsy of the lesion, which is often burdensome for the patient. Materials and Methods The authors bring their experience of four cases of bone lesions of the maxillofacial region and present a review of published studies. The imaging techniques evaluated are computed tomography (CT) and magnetic resonance imaging (MRI) with and without contrast...
December 2013: Journal of Neurological Surgery. Part B, Skull Base
Aldo Suarez-Soto, Mari-Carmen Baquero-Ruiz de la Hermosa, Ignacio Minguez-Martínez, Luis-Miguel Floría-García, Jose Barea-Gámiz, Jose Delhom-Valero, Presentation Risueño-Mata
INTRODUCTION: Fibro-osseous lesions constitute a rare benign type of pathology with a non-odontogenic lineage that affect the craniofacial area. According to Waldrom's classification, these lesions are divided into: fibrous dysplasia (FD), cemento-ossifying fibroma (COF) and desmoplastic fibroma (DF). MATERIAL AND METHODS: A retrospective study was performed on patients diagnosed with fibro-osseous lesions of the craniofacial area at the Hospital Universitario La Fe, Valencia, during 1987-2009...
May 2013: Medicina Oral, Patología Oral y Cirugía Bucal
Hongbo Yu, Steve Guofang Shen, Xudong Wang, Lei Zhang, Shilei Zhang
OBJECTIVE: To explore the indication and application of computer-assisted navigation in oral and maxillofacial surgery. PATIENTS AND METHODS: One hundred and four patients including 34 zygomatic-orbital-maxillary fractures, 27 unilateral TMJ ankylosis, 29 craniofacial fibrous dysplasia, 9 mandibular angle hypertrophia, 3 cartilage/bone tumours of jaw and 2 cases with facial foreign bodies were enrolled in this study. CT scans were performed and data was saved in DICOM (digital imaging and communications in medicine) format...
December 2013: Journal of Cranio-maxillo-facial Surgery
Edward F McCarthy
Fibro-osseous lesions of the maxillofacial bones should be classified based on their radiographic growth pattern. This method can simplify this category of lesions, which have considerable overlapping histologic features. These neoplasms can be grouped into three categories: (a) fibrous dysplasia; (b) ossifying fibroma; (c) and osseous dysplasia. Important lesions in the differential diagnosis are osteoblastoma and giant cell reparative granuloma.
March 2013: Head and Neck Pathology
Nikolaos Kolomvos, Nadia Theologie-Lygidakis, Panagiotis Christopoulos, Ioannis Iatrou
INTRODUCTION: Fibro-osseous lesions, a diverse group of bone disorders including developmental, reactive or dysplastic diseases and neoplasms, share overlapping clinical, radiographic and histopathologic features and demonstrate a wide range of biological behaviour. AIM: To evaluate the characteristics, treatment and outcome of benign fibro-osseous lesions of the jaws in children. PATIENTS AND METHOD: All patients with fibro-osseous lesions of the jaws treated at the department of Oral and Maxillofacial Surgery of the «A & P Kyriakou» Children's Hospital of Athens from 2000 to 2011 were included in this study...
October 2013: Journal of Cranio-maxillo-facial Surgery
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