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Fibro Osseous maxillofacial

Ahmed S Sultan, Michael K Schwartz, John F Caccamese, John C Papadimitriou, John Basile, Robert D Foss, Rania H Younis
Benign fibro-osseous lesions within the maxillofacial region represent a heterogeneous group of benign entities with overlapping histologic features. Ossifying fibroma, the rarest of these entities, represents a true neoplasm. Juvenile ossifying fibroma (JOF) is considered an aggressive rapidly growing sub-type. It tends to occur in the first or second decades of life. Based on histological and clinical features it can further be classified into two variants, namely juvenile trabecular ossifying fibroma (JTOF) and juvenile psammomatoid ossifying fibroma (JPOF)...
October 13, 2017: Head and Neck Pathology
Paul M Speight, Takashi Takata
The latest (4th) edition of the World Health Organization Classification of Head and Neck tumours has recently been published with a number of significant changes across all tumour sites. In particular, there has been a major attempt to simplify classifications and to use defining criteria which can be used globally in all situations, avoiding wherever possible the use of complex molecular techniques which may not be affordable or widely available. This review summarises the changes in Chapter 8: Odontogenic and maxillofacial bone lesions...
July 3, 2017: Virchows Archiv: An International Journal of Pathology
R Boeddinghaus, A Whyte
Maxillofacial imaging encompasses radiology of the teeth and jaws, including the temporomandibular joints. Modalities used include intra-oral radiographs, panoramic tomography, cephalograms, cone-beam computed tomography, computed tomography, magnetic resonance imaging, ultrasound, and radionuclide imaging. Common indications for imaging are impacted and supernumerary teeth, dental implants, inflammatory dental disease, and fibro-osseous lesions, cysts, and masses of the jaws. Osteonecrosis of the jaws may follow radiotherapy or the use of bisphosphonates and other drugs...
March 21, 2017: Clinical Radiology
G N Mainville, D P Turgeon, A Kauzman
Benign fibro-osseous lesions of the maxillofacial skeleton constitute a heterogeneous group of disorders that includes developmental, reactive (dysplastic) and neoplastic lesions. Although their classification has been reviewed multiple times in the past, the most common benign fibro-osseous lesions are fibrous dysplasia, osseous dysplasia and ossifying fibroma. For the dental clinician, the challenges involve diagnosis and treatment (or lack thereof). A careful correlation of all clinical, radiologic and microscopic features is essential to establish a proper diagnosis and a clear treatment plan...
May 2017: Oral Diseases
Rajat G Panigrahi, Sanat K Bhuyan, Abhishek R Pati, Smita R Priyadarshini, Snigdha Sagar
Benign osteoblastoma is a very rare, bone tumour occurring in the facial region. These lesions are most frequently seen in long bones. They are characterised by proliferation of compact or cancellous bone. The lesion is usually asymptomatic until it causes significant facial asymmetry or displacement of the teeth if present in the alveolar region. The clinical appearance of osteoblastoma is very similar to peripheral ossifying fibroma or any fibro-osseous lesion. The tumour is characterised by bone formation along with the presence of numerous osteoblasts...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
Yaser Safi, Nafise Shamloo, Hossein Heidar, Solmaz Valizadeh, Mohammad Mehdi Aghdasi, Maryam Eslami Manouchehri
Desmoplastic fibroma (DF) is a rare and locally aggressive intraosseous tumor with unknown etiology. The mandible is the common site of involvement in the maxillofacial region. However, it is believed that DF can arise in any bone of the body. A wide age distribution has been reported for DF occurrence, extending from birth to the sixth decade of life, with a peak incidence at 10 to 19 years of age. In this study, diagnostic and therapeutic management of a 6-year-old girl with a desmoplastic fibroma of the inferior orbital rim and zygomatic buttress are discussed...
July 2015: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
Sevtap Akbulut, Mehmet Gokhan Demir, Kayhan Basak, Mustafa Paksoy
OBJECTIVES: Osseous dysplasias are the most common subtype of fibro-osseous lesions of the maxillofacial bones. They are benign and often present as incidental asymptomatic lesions. Diagnosis can be made with clinical and radiographic examination. CASE REPORT: This article reports the case of a 47-year-old man with a huge cementifying osseous dysplasia of the maxilla that presented with secondary infection after teeth extraction and repair of oroantral fistula. A subtotal maxillectomy had to be done after conservative treatment failed to resolve the infection...
2015: Acta Medica (Hradec Králové)
Ramlal Gantala, Arjun Yadav Vemula, Jithender Reddy Kubbi, Ms Muni Sekhar, Dinesh Jhawar
Juvenile ossifying fibroma (JOF) is a fibro-osseous neoplasm, rare in occurrence and usually seen in young children. JOF is locally aggressive spreads quickly and is defined as a variant of ossifying fibroma. There are two types of ossifying fibroma depending on histopathology and classified as Psammomatoid juvenile ossifying fibroma (PJOF), Trabecular juvenile ossifying fibroma (TJOF). Both the types affect skull bones with the trabecular type being more common in the jaws- maxillofacial region and the psammomatoid type being more common in the paranasal sinuses, ethmoid sinuses- craniofacial region...
July 2015: Journal of Clinical and Diagnostic Research: JCDR
Mirna S Cordeiro, André R Backes, Antônio F Durighetto Júnior, Elmar H G Gonçalves, Jefferson X de Oliveira
Fibrous dysplasia (FD) is a developmental anomaly in which the normal medullary space of the affected bone is replaced by fibro-osseous tissue. This condition is typically encountered in adolescents and young adults. It affects the maxillofacial region and it can often cause severe deformity and asymmetry. Therefore, accurate diagnosis is critical to determine the appropriate treatment of each case. In this sense, computed tomography (CT) is a relevant resource among the imaging techniques for correct diagnosis of this condition...
February 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Prashanti Eachempati, Himanshi Aggarwal, Vidya Shenoy, Mohan Baliga
Fibrous dysplasia is a non-neoplastic hamartomatous developmental fibro-osseous lesion of bone. Monostotic fibrous dysplasia is more common than the polyostotic form and usually involves jaw bones, ribs and femur. Maxillary lesions may extend to involve the maxillary sinus, zygoma, sphenoid bone and floor of the orbit and require surgical intervention resulting in an acquired defect of the involved site. A multidisciplinary team approach involving an oral pathologist, oral surgeon, oral medicine expert and maxillofacial prosthodontist is required for successful treatment and rehabilitation of such patients...
August 5, 2015: BMJ Case Reports
K A Jeevan Kumar, P Krishna Kishore, A P Mohan, V Venkatesh, B Pavan Kumar, Divya Gandla
INTRODUCTION: Fibro-osseous lesions are a diverse group of bone disorders and include developmental, reactive or dysplastic diseases and neoplasms. They share overlapping clinical, radiographic and histopathologic features and demonstrate a wide range of biological behaviour. AIM: To evaluate the characteristics, treatment and outcome of benign fibro-osseous lesions of the jaws. PATIENTS AND METHOD: All patients with fibro-osseous lesions of the jaws treated at the department of Oral and Maxillofacial Surgery of the Kamineni Institute of Dental Sciences from 2007 to 2013 were included in this study...
September 2015: Journal of Maxillofacial and Oral Surgery
Amit Tyagi, Sunil Chaudhary, Vineet Gupta
Ossifying fibroma is a benign fibro-osseous lesion which occurs at various locations in maxillofacial region. A synchronous presentation of this lesion in both, the maxilla and the mandible is a rare occurrence. The present article reports a case of ossifying fibroma in a 45-year-old woman who manifested lesions in the right maxilla and mandible. The clinico-radiologic and histopathologic modalities of diagnosing this entity are evaluated and discussed.
March 2015: Journal of Maxillofacial and Oral Surgery
Shang-Hui Zhou, Wen-Jun Yang, Sheng-Wen Liu, Jiang Li, Chun-Ye Zhang, Yun Zhu, Chen-Ping Zhang
Fibrous dysplasia (FD) as an abnormal bone growth is one of the common fibro-osseous leasions (FOL) in oral and maxillofacial region, however, its etiology still remains unclear. Here, we performed gene expression profiling of FD using microarray analysis to explore the key molecule events in FD development, and develop potential diagnostic markers or therapeutic targets for FD. We found that 1,881 genes exhibited differential expression with more than two-fold changes in FD compared to normal bone tissues, including 1,200 upregulated genes and 681 downregulated genes...
2014: International Journal of Clinical and Experimental Pathology
D S MacDonald
During the last decade much has changed in our understanding of fibro-osseous lesions (FOLs) of the jaws with regards to their imaging, their nomenclature and classification, and their potential impact on the overall health of the patient. The changes in nomenclature, classification, and the FOLs' potential association with important syndromes are discussed with the assistance of a flowchart. The lesions, fibrous dysplasia (FD), ossifying fibroma (OF), and osseous dysplasia (OD), though with similar histopathology, have very different clinical and radiological presentations, behaviour, and treatment outcomes...
January 2015: Clinical Radiology
Ying-Bin Yan, Su-Xia Liang, Jun Shen, Jian-Cheng Zhang, Yi Zhang
Traumatic temporomandibular joint (TMJ) ankylosis can be classified into fibrous, fibro-osseous and bony ankylosis. It is still a huge challenge for oral and maxillofacial surgeons due to the technical difficulty and high incidence of recurrence. The poor outcome of disease may be partially attributed to the limited understanding of its pathogenesis. The purpose of this article was to comprehensively review the literature and summarise results from both human and animal studies related to the genesis of TMJ ankylosis...
2014: Head & Face Medicine
Aniket B Jadhav, Aditya Tadinada, Kandasamy Rengasamy, Douglas Fellows, Alan G Lurie
An osteolytic lesion with a small central area of mineralization and sclerotic borders was discovered incidentally in the clivus on the cone-beam computed tomography (CBCT) of a 27-year-old male patient. This benign appearance indicated a primary differential diagnosis of non-aggressive lesions such as fibro-osseous lesions and arrested pneumatization. Further, on magnetic resonance imaging (MRI), the lesion showed a homogenously low T1 signal intensity with mild internal enhancement after post-gadolinium and a heterogeneous T2 signal intensity...
June 2014: Imaging Science in Dentistry
L M Muwazi, A Kamulegeya
BACKGROUND: Fibro-osseous lesions of the jaws are a diagnostic challenge for the pathologist because histologically, they are not easily distinguishable. African data on the prevalence of these lesions are scarce. We present a 5-year report of benign fibro-osseous lesions at Mulago Hospital, Uganda, showing the frequency and distribution of these lesions. MATERIALS AND METHODS: Confirmed fibro-osseous lesions reports at the pathology department (2007-2012) were retrieved...
January 2015: Oral Diseases
Ramesh Krishnan, Maya Ramesh, George Paul
AIM: The aim of the study was to evaluate the pediatric oral biopsies received between 2002-2011 from a dental and maxillofacial centre in Salem, Tamilnadu, India retrospectively based on age, sex, site and type of the pathologies. MATERIALS AND METHODS: The records of dental and maxillofacial surgery centre were taken and a retrospective evaluation of the pediatric lesions biopsied over a period of ten years (2002-2011) was done. Patients aged 15 years and below were considered as pediatric patients and pathologies were grouped into 8 categories, according to age, gender, anatomic location and pathologic diagnosis...
January 2014: Journal of Clinical and Diagnostic Research: JCDR
Ahmed O Al Yamani, Maisa O Al Sebaei, Lojain J Bassyoni, Alaa J Badghaish, Hussam H Shawly
This study was conducted to present a comprehensive view of the most common head and neck pathologies among the pediatric and adolescent population of the city of Jeddah, Saudi Arabia. Data were collected from the oral and maxillofacial surgery (OMFS) records at King Abdulaziz University Hospital and King Fahad Hospital Jeddah (KFHJ) from the period 1998 to 2009. All patients who were 18 years of age and younger were included in the study. Identified lesions were classified into four categories: cystic, neoplastic, vascular and fibro-osseous...
October 2011: Saudi Dental Journal
Aldo Suarez-Soto, Mari-Carmen Baquero-Ruiz de la Hermosa, Ignacio Minguez-Martínez, Luis-Miguel Floría-García, Jose Barea-Gámiz, Jose Delhom-Valero, Presentation Risueño-Mata
INTRODUCTION: Fibro-osseous lesions constitute a rare benign type of pathology with a non-odontogenic lineage that affect the craniofacial area. According to Waldrom's classification, these lesions are divided into: fibrous dysplasia (FD), cemento-ossifying fibroma (COF) and desmoplastic fibroma (DF). MATERIAL AND METHODS: A retrospective study was performed on patients diagnosed with fibro-osseous lesions of the craniofacial area at the Hospital Universitario La Fe, Valencia, during 1987-2009...
May 2013: Medicina Oral, Patología Oral y Cirugía Bucal
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