keyword
https://read.qxmd.com/read/38536613/identification-of-a-clinical-spirometra-mansoni-plerocercoid-isolate-using-molecular-and-morphological-data
#21
JOURNAL ARTICLE
Si Si Ru, Chi Cheng, Peng Jiang, Xi Zhang
Sparganosis has been a neglected parasitic zoonosis for a long time. The accurate identification of Spirometra tapeworms in clinical practice is poorly understood. A case of breast sparganosis was reported in Henan Province of central China. One plerocercoid approximately 3.5 cm in length was collected from the patient. The clinical isolate was identified as Spirometra mansoni based on the barcoding sequences of mitochondrial cytochrome c oxidase subunit 1 (cox1). Finally, the epidemiology of sparganosis in central China was reviewed...
March 27, 2024: Acta Parasitologica
https://read.qxmd.com/read/38536536/what-keeps-the-style-under-tension-experimental-tests-to-understand-the-biomechanics-of-the-explosive-style-movement-in-marantaceae
#22
JOURNAL ARTICLE
Marcus Jerominek, Regine Claßen-Bockhoff
Pollination in Marantaceae is mediated by an explosive style movement. Before release, style tension is held by the hooded staminode. When a pollinator touches the trigger appendage of the hooded staminode the latter deforms and the style rapidly curls upwards. This movement has been interpreted as a turgor movement by some authors, but recent studies clearly indicate that setup, hold and release of tension are purely mechanical processes. However, in view of the high diversity of hooded staminodes, the question arises what keeps the tension in species with very thin staminodes...
March 27, 2024: Journal of Plant Research
https://read.qxmd.com/read/38536397/antifungal-activity-and-putative-mechanism-of-hwy-289-a-semisynthetic-protoberberine-derivative-against-botrytis-cinerea
#23
JOURNAL ARTICLE
Jun-Xia An, Bao-Qi Zhang, Hong-Jie Liang, Zhi-Jun Zhang, Ying-Qian Liu, Shao-Yong Zhang
The emergence of resistant pathogens has increased the demand for alternative fungicides. The use of natural products as chemical scaffolds is a potential method for developing fungicides. HWY-289, a semisynthetic protoberberine derivative, demonstrated broad-spectrum and potent activities against phytopathogenic fungi, particularly Botrytis cinerea (with EC50 values of 1.34 μg/mL). SEM and TEM imaging indicated that HWY-289 altered the morphology of the mycelium and the internal structure of cells. Transcriptomics revealed that it could break down cellular walls through amino acid sugar and nucleotide sugar metabolism...
March 27, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38536036/the-gtpase-activating-protein-gyp7-regulates-rab7-ypt7-activity-on-late-endosomes
#24
JOURNAL ARTICLE
Nadia Füllbrunn, Raffaele Nicastro, Muriel Mari, Janice Griffith, Eric Herrmann, René Rasche, Ann-Christin Borchers, Kathrin Auffarth, Daniel Kümmel, Fulvio Reggiori, Claudio De Virgilio, Lars Langemeyer, Christian Ungermann
Organelles of the endomembrane system contain Rab GTPases as identity markers. Their localization is determined by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs). It remains largely unclear how these regulators are specifically targeted to organelles and how their activity is regulated. Here, we focus on the GAP Gyp7, which acts on the Rab7-like Ypt7 protein in yeast, and surprisingly observe the protein exclusively in puncta proximal to the vacuole. Mistargeting of Gyp7 to the vacuole strongly affects vacuole morphology, suggesting that endosomal localization is needed for function...
June 3, 2024: Journal of Cell Biology
https://read.qxmd.com/read/38535998/targeting-mitochondrial-dysfunction-using-methylene-blue-or-mitoquinone-to-improve-skeletal-aging
#25
JOURNAL ARTICLE
Sher Bahadur Poudel, Dorra Frikha-Benayed, Ryan R Ruff, Gozde Yildirim, Manisha Dixit, Ron Korstanje, Laura Robinson, Richard A Miller, David E Harrison, John R Strong, Mitchell B Schaffler, Shoshana Yakar
Methylene blue (MB) is a well-established antioxidant that has been shown to improve mitochondrial function in both in vitro and in vivo settings. Mitoquinone (MitoQ) is a selective antioxidant that specifically targets mitochondria and effectively reduces the accumulation of reactive oxygen species. To investigate the effect of long-term administration of MB on skeletal morphology, we administered MB to aged (18 months old) female C57BL/J6 mice, as well as to adult male and female mice with a genetically diverse background (UM-HET3)...
March 25, 2024: Aging
https://read.qxmd.com/read/38535976/reversible-cspbbr-3-%C3%A2-cspb-2-br-5-transformation-via-reverse-micellar-aqueous-solution
#26
JOURNAL ARTICLE
Subhashree Sahu, Tushar Debnath, Kalyanasis Sahu
Lead halide perovskites suffer from water and moisture instability due to the highly ionic nature of the crystal structures, though a few groups took advantage of it for chemical transformation via water-assisted strategy. However, direct exposure of the perovskite to bulk water leads to uncontrolled chemical transformation. Here, we report a controlled chemical transformation of CsPbBr3 to CsPb2 Br5 triggered by nanoconfined water by placing CsPbBr3 in the nonpolar phase within a reverse micelle. The chemical transformation reaction is probed by using steady-state and time-resolved optical spectroscopy...
March 27, 2024: Journal of Physical Chemistry Letters
https://read.qxmd.com/read/38535927/effects-of-indigo-carmine-on-growth-cell-division-and-morphology-of-allium-cepa-l-root-tip
#27
JOURNAL ARTICLE
Madalina-Elena Ristea, Otilia Zarnescu
Indigo carmine has a variety of uses in foods, textiles, medicine, pharmaceuticals, and cosmetics. There are studies reporting the toxic potential of indigo carmine on human health and the environment. In this study, we investigated the cytogenotoxic effects of indigo carmine using apical root cells of Allium cepa . Allium cepa bulbs were subjected to four treatments with indigo carmine (0.0032, 0.0064, 0.0125, and 0.2 mg/mL) and to ultrapure water as a control. After 5 days, root growth, root length, mitotic index, mitotic inhibition, chromosomal anomalies, and cell morphology were analyzed...
March 1, 2024: Toxics
https://read.qxmd.com/read/38535925/per-and-polyfluoroalkyl-substances-impacts-on-morphology-behavior-and-lipid-levels-in-zebrafish-embryos
#28
JOURNAL ARTICLE
Janice Albers, John Mylroie, Ashley Kimble, Catherine Steward, Kacy Chapman, Mitchell Wilbanks, Edward Perkins, Natàlia Garcia-Reyero
The presence of per- and polyfluoroalkyl substances (PFASs) in aquatic environments is often persistent and widespread. Understanding the potential adverse effects from this group of chemicals on aquatic communities allows for better hazard characterization. This study examines impacts on zebrafish ( Danio rerio ) embryo physiology, behavior, and lipid levels from exposure to perfluorooctanoic acid (PFOA), perfluorohexane sulfonate (PFHxS), and heptadecafluorooctanesulfonic acid (PFOS). Embryos were exposed to lethal and sublethal levels of each chemical and monitored for alterations in physiological malformations, mortality, lipid levels, and behavior (only PFOA and PFHxS)...
February 29, 2024: Toxics
https://read.qxmd.com/read/38535898/sustainable-development-of-zno-nanostructure-doping-with-water-hyacinth-derived-activated-carbon-for-visible-light-photocatalysis
#29
JOURNAL ARTICLE
Sucheewan Krobthong, Tipawan Rungsawang, Naphatson Khaodara, Napat Kaewtrakulchai, Kanit Manatura, Khewika Sukiam, Donchida Wathinputthiporn, Sawitree Wongrerkdee, Chatdanai Boonruang, Sutthipoj Wongrerkdee
Water hyacinth (Wh) is an aquatic weed considered a nuisance in agricultural and fishing activities. Therefore, this study proposed repurposing this plant into activated carbon (AC). First, the ZnO-AC was precipitated and applied as a photocatalyst for degrading methylene blue. The preliminary photocatalytic test under UV irradiation identified the optimum ZnO-AC photocatalyst to degrade methylene blue (MB). The ZnO-AC photocatalyst recorded the highest degradation rate constant of 11.49 × 10-3 min-1 , which was almost two-fold higher than that of ZnO (5...
February 21, 2024: Toxics
https://read.qxmd.com/read/38535875/ecology-and-infection-status-of-sand-flies-in-rural-and-urban-cutaneous-leishmaniasis-endemic-areas-in-northwest-ethiopia
#30
JOURNAL ARTICLE
Wondmeneh Jemberie, Abebe Animut, Sisay Dugassa, Araya Gebresilassie, Roma Melkamu, Esayas Aklilu, Mulugeta Aemero, Johan van Griensven, Myrthe Pareyn
Cutaneous leishmaniasis (CL) caused by Leishmania aethiopica is transmitted by Phlebotomus longipes in northern Ethiopia. No studies have been conducted to investigate the transmission dynamics of CL, despite its high endemicity in both rural and urban settings. Evidence on the ecology and behavior of the vector from this area are required to develop integrated disease control strategies. Sand flies were collected in the dry and wet seasons in 2021 in CL-endemic rural Gindmeteaye and urban Addis-Alem in northwest Ethiopia...
February 23, 2024: Tropical Medicine and Infectious Disease
https://read.qxmd.com/read/38535840/in-vitro-antimycotic-activity-and-structural-damage-against-canine-malassezia-pachydermatis-strains-caused-by-mexican-stingless-bee-propolis
#31
JOURNAL ARTICLE
Diana Berenice Fuentes Esquivel, Betsabé Rodríguez Pérez, Nelly Tovar Betancourt, Carlos Gerardo García Tovar, José Guillermo Penieres Carrillo, Florentina Hernández Galindo, Javier Pérez Flores, Tonatiuh Alejandro Cruz Sánchez
This work describes the antimycotic activity of propolis from the stingless bees Scaptotrigona mexicana and Tetragonisca angustula , collected from two Mexican regions (Veracruz and Chiapas, respectively), against three clinical isolates and the reference strain ATCC 14522 of Malassezia pachydermatis , the causative agent of canine otitis. The chemical components of the ethanolic extracts of propolis were determined by gas chromatography coupled with mass spectrometry (GC-MS), and sesquiterpenes were the predominant compounds...
February 28, 2024: Veterinary Sciences
https://read.qxmd.com/read/38535810/environmental-toxin-biliatresone-induced-biliary-atresia-like-abnormal-cilia-and-bile-duct-cell-development-of-human-liver-organoids
#32
JOURNAL ARTICLE
Yue Hai-Bing, Menon Sudheer Sivasankaran, Babu Rosana Ottakandathil, Wu Zhong-Luan, So Man-Ting, Chung Patrick Ho-Yu, Wong Kenneth Kak-Yuen, Tam Paul Kwong-Hang, Lui Vincent Chi-Hang
Biliary atresia (BA) is a poorly understood and devastating obstructive bile duct disease of newborns. Biliatresone, a plant toxin, causes BA-like syndrome in some animals, but its relevance in humans is unknown. To validate the hypothesis that biliatresone exposure is a plausible BA disease mechanism in humans, we treated normal human liver organoids with biliatresone and addressed its adverse effects on organoid development, functions and cellular organization. The control organoids (without biliatresone) were well expanded and much bigger than biliatresone-treated organoids...
March 11, 2024: Toxins
https://read.qxmd.com/read/38535808/potential-biotechnological-applications-of-venoms-from-the-viperidae-family-in-central-america-for-thrombosis
#33
REVIEW
Jorge Eduardo Chang Estrada, Taissa Nunes Guerrero, Daniel Fernando Reyes-Enríquez, Erica Santos Nardy, Roseane Guimarães Ferreira, Cristian José Ruiz Calderón, Irmgardt A Wellmann, Kaio Murilo Monteiro Espíndola, Alejandro Ferraz do Prado, Andreimar Martins Soares, Marcos Roberto de Mattos Fontes, Marta Chagas Monteiro, Russolina Benedeta Zingali
Central America is home to one of the most abundant herpetofauna in the Americas, occupying only 7% of the continent's total area. Vipers and lizards are among the most relevant venomous animals in medical practice due to the consequences of envenomation from the bite of these animals. A great diversity of biomolecules with immense therapeutic and biotechnological value is contained in their venom. This paper describes the prominent leading representatives of the family Viperidae , emphasizing their morphology, distribution, habitat, feeding, and venom composition, as well as the biotechnological application of some isolated components from the venom of the animals from these families, focusing on molecules with potential anti-thrombotic action...
March 8, 2024: Toxins
https://read.qxmd.com/read/38535801/hortensins-type-1-ribosome-inactivating-proteins-from-seeds-of-red-mountain-spinach-isolation-characterization-and-their-effect-on-glioblastoma-cells
#34
JOURNAL ARTICLE
Sara Ragucci, Veronica Russo, Angela Clemente, Maria Giuseppina Campanile, Maria Antonietta Oliva, Nicola Landi, Paolo Vincenzo Pedone, Antonietta Arcella, Antimo Di Maro
Ribosome inactivating proteins (RIPs) are specific N-β-glycosylases that are well-characterized in plants. Their enzymatic action is to damage ribosomes, thereby blocking protein translation. Recently, several research groups have been working on the screening for these toxins in edible plants to facilitate the use of RIPs as biotechnological tools and biopesticides and to overcome public prejudice. Here, four novel monomeric (type 1) RIPs have been isolated from the seeds of Atriplex hortensis L. var...
March 4, 2024: Toxins
https://read.qxmd.com/read/38535784/association-of-urinary-mycotoxins-with-sperm-quality-a-case-control-study-in-southern-nigeria
#35
JOURNAL ARTICLE
Friday Ebhodaghe Okonofua, Lorretta Favour Chizomam Ntoimo, Emmanuel Iyayi Unuabonah, Titus Afred Makudali Msagati, Oladiran Ayodeji, Michael Aziken, Akhere Omonkhua, Victor Ohenhen, Celestina Olafusi, Moses O Alfred
The objective of this study was to determine the association between mycotoxins and the quality of spermatozoa in Nigeria. We designed a prospective case-control study involving 136 men diagnosed with reduced sperm count and quality in five infertility clinics in southwest Nigeria and 154 normal fertile controls. Sperm analysis was conducted in accordance with the recommendations of the World Health OrganizationWHO, while Liquid Chromatography-Mass Spectrometry was used to assay three metabolites of mycotoxins (zearalenone, ochratoxin A, and deoxyvinelol) in the urine samples of cases and controls...
February 29, 2024: Toxins
https://read.qxmd.com/read/38535754/structure-and-morphology-of-red-pigments-based-on-sepiolite
#36
JOURNAL ARTICLE
I Carrillo, E Atanes-Sánchez, F Fernández-Martínez
Sepiolite is an important raw fibrous material. A method to prepare red pigments based on sepiolite through the thermal treatment of sepiolite with sulfur and sodium sulfide hydrate is reported. Sepiolite was heated until 800 °C in order to remove zeolitic water, the first coordinated water, the second coordinated water, and structural hydroxyls. Several [S/Na2 S]molar ratios in the range 0.5-7 were employed. The properties of these pigments were studied by different analytical techniques, such as colorimetric analysis, thermal analysis, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction and scanning electron microscopy...
March 27, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
https://read.qxmd.com/read/38535732/isak-based-anthropometric-standards-for-elite-male-and-female-soccer-players
#37
JOURNAL ARTICLE
Cristian Petri, Francesco Campa, Francis Holway, Luca Pengue, Luis Suarez Arrones
This study aimed to provide reference values for anthropometric characteristics of elite male and female soccer players, considering a group of individuals from the general population as controls. The anthropometric profiles of 357 elite soccer players [184 males (age 24.3 ± 4.3 y) and 173 females (age 25.2 ± 5.1 y)] participating in the first Italian league (Serie A) and 363 subjects from the general population [188 males (age 24.2 ± 4.8 y) and 175 females (age 25.0 ± 5.1 y)] were measured according to the guidelines of the International Society for the Advancement of Kinanthropometry (ISAK)...
February 23, 2024: Sports
https://read.qxmd.com/read/38535702/synthesis-and-unique-behaviors-of-high-purity-hea-nanoparticles-using-femtosecond-laser-ablation
#38
JOURNAL ARTICLE
David Fieser, Yucheng Lan, Antonino Gulino, Giuseppe Compagnini, Doug Aaron, Matthew Mench, Denzel Bridges, Hugh Shortt, Peter Liaw, Anming Hu
High-entropy alloys (HEAs) are a class of metal alloys consisting of four or more molar equal or near-equal elements. HEA nanomaterials have garnered significant interest due to their wide range of applications, such as electrocatalysis, welding, and brazing. Their unique multi-principle high-entropy effect allows for the tailoring of the alloy composition to facilitate specific electrochemical reactions. This study focuses on the synthesis of high-purity HEA nanoparticles using the method of femtosecond laser ablation synthesis in liquid...
March 21, 2024: Nanomaterials
https://read.qxmd.com/read/38535693/quantifying-the-size-dependent-shear-banding-behavior-in-high-entropy-alloy-based-nanolayered-glass
#39
JOURNAL ARTICLE
Kaiqing Dai, Chun Zhang, Wenjun Lu, Jianjun Li
Extensive research has shown that nanolayered structures are capable of suppressing the shear banding in metallic glass in nanoindentation experiments. However, the specific mode and mechanism of the shear banding underneath the indenter remains unknown. Also, the quantification of shear banding-induced strain localization is still a challenge. Herein, the size-dependent shear banding behavior of a CuTiZrNb high-entropy alloy-based nanolayered glass with individual layer thicknesses ( h ) ranging from 5 to 80 nm was systematically investigated by nanoindentation tests...
March 20, 2024: Nanomaterials
https://read.qxmd.com/read/38535689/cobalt-ferrite-nanorods-synthesized-with-a-facile-green-method-in-a-magnetic-field
#40
JOURNAL ARTICLE
Alexander L Kwiatkowski, Petr V Shvets, Ivan S Timchenko, Darya E Kessel, Elizaveta D Shipkova, Konstantin I Maslakov, Ivan A Kuznetsov, Dmitry A Muravlev, Olga E Philippova, Andrey V Shibaev
We report a new facile method for the synthesis of prolate cobalt ferrite nanoparticles without additional stabilizers, which involves a co-precipitation reaction of Fe3+ and Co2+ ions in a static magnetic field. The magnetic field is demonstrated to be a key factor for the 1D growth of cobalt ferrite nanocrystals in the synthesis. Transmission electron microscopy (TEM), X-ray diffraction (XRD), and Raman spectroscopy are applied to characterize the morphology and structure of the obtained nanoparticles. According to TEM, they represent nanorods with a mean length of 25 nm and a diameter of 3...
March 20, 2024: Nanomaterials
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