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Ocular movement

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https://www.readbyqxmd.com/read/29325383/-clinical-features-and-surgical-outcomes-of-acute-acquired-comitant-esotropia
#1
M Y Ren, Q Wang, L H Wang
Objective: To investigate the clinical features and surgical outcomes of patients with acute acquired concomitant esotropia (AACE) type Ⅱ(AACE-Ⅱ) and type Ⅲ (AACE-Ⅲ). Methods: Retrospective case series analysis. Medical records of consecutive patients who underwent strabismus surgery for AACE-Ⅱ and AACE-Ⅲ in Shandong Provincial Hospital affiliated to Shandong University between January 2011 and June 2016 with a minimum follow-up time of 3 months were collected. Each patient underwent a complete ophthalmological and orthoptic examination to exclude esotropia resulting from other reasons, and a systemic assessment to exclude AACE related to intracranial and systemic diseases...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29319595/pythium-keratitis-leading-to-fatal-cavernous-sinus-thrombophlebitis
#2
Anubha Rathi, Arunaloke Chakrabarti, Tushar Agarwal, Neelam Pushker, Mukesh Patil, Hemant Kamble, Jeewan S Titiyal, Rishi Mohan, Seema Kashyap, Sanjay Sharma, Seema Sen, Gita Satpathy, Namrata Sharma
PURPOSE: To report a case of Pythium insidiosum keratitis leading to fatal cavernous sinus thrombophlebitis. METHODS: Case report. RESULTS: A 70-year-old man presented with excruciating pain, redness, and diminution of vision in his left eye for 2 weeks after washing his hair with tap water. A total corneal ulcer with surrounding infiltrates and associated corneal thinning was present. Corneal scraping revealed the presence of Gram-positive cocci...
January 9, 2018: Cornea
https://www.readbyqxmd.com/read/29288733/ophthalmic-gels-past-present-and-future
#3
Ali A Al-Kinani, Ghada Zidan, Naba Elsaid, Ali Seyfoddin, Adam W G Alani, Raid G Alany
Aqueous gels formulated using hydrophilic polymers (hydrogels) along with those based on stimuli responsive polymers (in situ gelling or gel forming systems) continue to attract increasing interest for various eye health-related applications. They allow the incorporation of a variety of ophthalmic pharmaceuticals to achieve sustained and therapeutic levels of drugs and bioactives at target ocular sites. The integration of sophisticated drug delivery technologies such as nanotechnology-based, intelligent and environment responsive systems can extend current treatment duration to provide more clinically relevant time courses (weeks and months instead of hours and days) which will inevitably reduce dose frequency, increase patient compliance and improve clinical outcomes...
December 27, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29279653/clinical-profile-and-outcomes-of-optic-neuritis-in-an-hiv-prevalent-urban-community-in-south-africa
#4
Hamzah Mustak, Colin Cook
PURPOSE: To determine the clinical profile, causes and response to corticosteroid therapy in patients admitted and treated for optic neuritis at a tertiary hospital in Cape Town, South Africa. METHODS: A retrospective case review of 117 patients with optic neuritis between January 2002 and December 2012. Demographic information, clinical presentation, course of illness, investigations performed and visual outcomes at discharge and at three month follow up were collected for analysis...
July 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/29260439/eye-movement-research-in-the-twenty-first-century-a-window-to-the-brain-mind-and-more
#5
EDITORIAL
Aasef G Shaikh, David S Zee
The study of eye movements not only addresses debilitating neuro-ophthalmological problems but has become an essential tool of basic neuroscience research. Eye movements are a classic way to evaluate brain function-traditionally in disorders affecting the brainstem and cerebellum. Abnormalities of eye movements have localizing value and help narrow the differential diagnosis of complex neurological problems. More recently, using sophisticated behavioral paradigms, measurement of eye movements has also been applied to disorders of the thalamus, basal ganglia, and cerebral cortex...
December 19, 2017: Cerebellum
https://www.readbyqxmd.com/read/29258460/a-case-of-proliferative-diabetic-retinopathy-in-which-scintillating-particles-appeared-in-the-intravitreal-cavity-after-laser-photocoagulation
#6
Ryohsuke Kohmoto, Takatoshi Kobayashi, Takaki Sato, Daisaku Kimura, Masanori Fukumoto, Kensuke Tajiri, Teruyo Kida, Tsunehiko Ikeda
BACKGROUND: To report a case of proliferative diabetic retinopathy (PDR) exhibiting the appearance of scintillating particles presumed to be crystallin inside the intravitreal cavity after laser photocoagulation. CASE PRESENTATION: A 56-year-old male patient presented at our outpatient clinic after becoming aware of decreased vision in his right eye. Ocular examination performed at the patient's initial visit revealed a massive preretinal macular hemorrhage due to PDR in his right eye...
December 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29249386/eye-movement-abnormalities-in-aqp4-igg-positive-neuromyelitis-optica-spectrum-disorder
#7
Houliang Sun, Shilei Cui, Fei Gao, Qisheng You, Yong Li, Jiawei Wang, Xiaojun Zhang
BACKGROUND AND PURPOSE: Neuromyelitis optica spectrum disorder (NMOSD) has been recognized as a disease characterized by severe visual afferent impairment. Abnormal eye movements, as the other important neuro-ophthalmic manifestation of NMOSD, were commonly overlooked. The aim of our study was to describe the ocular motor manifestations of AQP4-IgG positive NMOSD patients, and explore the value of eye movement abnormalities in the evaluation of the disabled disease. METHODS: Systemic clinical bedside ocular motor examinations and quantitative horizontal saccadic eye movement assessments were performed in 90 patients with AQP4-IgG positive NMOSD...
January 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29246608/patterns-and-modulations-of-pendular-nystagmus-in-a-family-with-hereditary-spastic-paraplegia
#8
Eun Hye Oh, Jae-Hyeok Lee, Jin-Hong Shin, Hyang-Sook Kim, Ji-Soo Kim, Hyo-Jung Kim, Seo-Young Choi, Kwang-Dong Choi, David S Zee, Jae-Hwan Choi
Hereditary spastic paraplegia (HSP) is characterized by progressive spasticity and weakness of the lower extremities. Additional findings include ataxia, extrapyramidal signs, and dementia. Pendular nystagmus (PN) has been reported in some subtypes of HSP caused by PLP1 (SPG2) or paraplegin (SPG7) mutation. To describe the patterns and modulation of PN in HSP, we performed eye movement recording using video-oculography in a Korean family with HSP and PN. The PN was convergent-divergent in the oblique plane with a frequency of 6 to 7Hz and maximum amplitude at about 1...
December 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29233456/corneal-conjunctival-effects-and-blood-flow-changes-related-to-silicone-hydrogel-lens-wear-and-their-correlations-with-end-of-day-comfort
#9
Luigina Sorbara, Jyotsna Maram, Trefford Simpson, Natalie Hutchings
PURPOSE: First, to examine how wearing high and low modulus lenses with two different base curves affected lens fit, and the corneal tissue and bulbar conjunctival vascular tissue (bulbar redness and blood velocity). Secondly, to quantify the associations between these baseline and outcome variables and the third purpose was to correlate these variables with end of day comfort. METHODS: Thirty participants wore higher (PureVision (PV) 8.3, 8.6) and lower (Acuvue Advance (AA) 8...
December 7, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29220126/can-the-retina-be-used-to-diagnose-and-plot-the-progression-of-alzheimer-s-disease
#10
REVIEW
Deepti Mahajan, Marcela Votruba
Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of senile dementia. It impairs the quality of life of a person and their family, posing a serious economic and social threat in developed countries. The fact that the diagnosis can only be definitively made post-mortem, or when the disease is fairly advanced, presents a serious problem if novel therapeutic interventions are to be devised and used early in the course of the disease. There is therefore a pressing need for more sensitive and specific diagnostic tests with which we can detect AD in the preclinical stage...
December 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29209271/development-and-implementation-of-a-new-telerehabilitation-system-for-audiovisual-stimulation-training-in-hemianopia
#11
Francesca Tinelli, Giovanni Cioni, Giulia Purpura
Telerehabilitation, defined as the method by which communication technologies are used to provide remote rehabilitation, although still underused, could be as efficient and effective as the conventional clinical rehabilitation practices. In the literature, there are descriptions of the use of telerehabilitation in adult patients with various diseases, whereas it is seldom used in clinical practice with child and adolescent patients. We have developed a new audiovisual telerehabilitation (AVT) system, based on the multisensory capabilities of the human brain, to provide a new tool for adults and children with visual field defects in order to improve ocular movements toward the blind hemifield...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29200430/long-term-sensorimotor-adaptation-in-the-ocular-following-system-of-primates
#12
Markus A Hietanen, Nicholas S C Price, Shaun L Cloherty, Kostas Hadjidimitrakis, Michael R Ibbotson
The sudden movement of a wide-field image leads to a reflexive eye tracking response referred to as short-latency ocular following. If the image motion occurs soon after a saccade the initial speed of the ocular following is enhanced, a phenomenon known as post-saccadic enhancement. We show in macaque monkeys that repeated exposure to the same stimulus regime over a period of months leads to progressive increases in the initial speeds of ocular following. The improvement in tracking speed occurs for ocular following with and without a prior saccade...
2017: PloS One
https://www.readbyqxmd.com/read/29180845/clinical-outcomes-of-endoscope-assisted-vitrectomy-for-treatment-of-rhegmatogenous-retinal-detachment
#13
Sho Yokoyama, Takashi Kojima, Toshio Mori, Taisuke Matsuda, Hiroyuki Sato, Norihiko Yoshida, Tatsushi Kaga, R Theodore Smith, Kazuo Ichikawa
Summary: We evaluated the clinical outcomes for ophthalmic endoscope-assisted vitrectomy in consecutive patients with uncomplicated rhegmatogenous retinal detachment (RRD). The primary success rate was 98.4% (125/127) without performing a posterior drainage retinotomy or using perfluorocarbon liquids (PFCL) for subretinal fluid drainage. Purpose: To investigate the clinical outcomes of endoscope-assisted vitrectomy in patients with uncomplicated RRD. Methods: We examined 127 eyes from consecutive patients who underwent repair of RRD by 23- or 25-gauge endoscope-assisted vitrectomy, with a minimum follow-up of 3 months...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29177103/postural-control-and-emotion-in-children-with-autism-spectrum-disorders
#14
Nathalie Gouleme, Isabelle Scheid, Hugo Peyre, Magali Seassau, Anna Maruani, Julia Clarke, Richard Delorme, Maria Pia Bucci
Autism Spectrum Disorders subjects (ASD) are well known to have deficits in social interaction. We recorded simultaneously eye movements and postural sway during exploration of emotional faces in children with ASD and typically developing children (TD). We analyzed several postural and ocular parameters. The results showed that all postural parameters were significantly greater in children with ASD; ASD made significantly fewer saccades and had shorter fixation time than TD, particularly in the eyes, and especially for unpleasant emotions...
2017: Translational Neuroscience
https://www.readbyqxmd.com/read/29170018/ocular-torsion-responses-to-sinusoidal-electrical-vestibular-stimulation
#15
Stuart W Mackenzie, Raymond F Reynolds
BACKGROUND: Eye movements evoked by electrical vestibular stimulation (EVS) offer potential for diagnosing vestibular dysfunction. However, ocular recording techniques are often too invasive or impractical for routine clinical use. Furthermore, the kinematic nature of the EVS signal is not fully understood in terms of movement sensations. NEW METHOD: We apply sinusoidal EVS stimuli varying from 0.05 to 20Hz, and record the eye in darkness using an infrared camera...
November 20, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29169367/image-based-quantitative-analysis-of-tear-film-lipid-layer-thickness-for-meibomian-gland-evaluation
#16
Hyeonha Hwang, Hee-Jae Jeon, Kin Choong Yow, Ho Sik Hwang, EuiHeon Chung
BACKGROUND: Dry eye syndrome is one of the most common ocular diseases, and meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye syndrome. When the tear film lipid layer becomes thin due to obstructive or hyposecretory meibomian gland dysfunction, the excessive evaporation of the aqueous layer can occur, and this causes evaporative dry eye syndrome. Thus, measuring the lipid layer thickness (LLT) is essential for accurate diagnosis and proper treatment of evaporative dry eye syndrome...
November 23, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29158673/novel-cationic-lipid-nanoparticles-as-an-ophthalmic-delivery-system-for-multicomponent-drugs-development-characterization-in-vitro-permeation-in-vivo-pharmacokinetic-and-molecular-dynamics-studies
#17
Jialu Wang, Fang Zhao, Rui Liu, Jingjing Chen, Qinghua Zhang, Ruijuan Lao, Ze Wang, Xin Jin, Changxiao Liu
The purpose of this study was to prepare, optimize, and characterize a cationic lipid nanoparticle (CLN) system containing multicomponent drugs using a molecular dynamics model as a novel method of evaluating formulations. Puerarin (PUE) and scutellarin (SCU) were used as model drugs. CLNs were successfully prepared using melt-emulsion ultrasonication and low temperature-solidification technique. The properties of CLNs such as morphology, particle size, zeta potential, entrapment efficiency (EE), drug loading (DL), and drug release behavior were investigated...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29149358/clinically-directed-neuroimaging-of-ophthalmoplegia
#18
REVIEW
Lucia Danieli, Margherita Montali, Luca Remonda, Hanspeter E Killer, Cesare Colosimo, Alessandro Cianfoni
PURPOSE: Ophthalmoplegia (OP) can have numerous etiologies and different clinical presentations. Most causes of OP can be narrowed down to specific anatomical locations based on clinical information. The aim of this study was to outline the different categories of diseases encountered in patients with OP, based on the location along the ocular motor pathways, and the most appropriate imaging modality for the given scenarios. METHODS: Representative neuroimaging examples of pathological processes causing OP are displayed, sequenced by anatomical location and disease category...
November 17, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29147731/the-influence-of-cervical-movement-on-eye-stabilization-reflexes-a-randomized-trial
#19
Britta K Ischebeck, Jurryt de Vries, Jan Paul van Wingerden, Gert Jan Kleinrensink, Maarten A Frens, Jos N van der Geest
To investigate the influence of the amount of cervical movement on the cervico-ocular reflex (COR) and vestibulo-ocular reflex (VOR) in healthy individuals. Eye stabilization reflexes, especially the COR, are changed in neck pain patients. In healthy humans, the strength of the VOR and the COR are inversely related. In a cross-over trial the amplitude of the COR and VOR (measured with a rotational chair with eye tracking device) and the active cervical range of motion (CROM) was measured in 20 healthy participants (mean age 24...
November 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29147565/operating-room-central-serous-chorioretinopathy
#20
Ahmad M Mansour, Rola Hamam
Objectives: The operating room is a place of surgical intervention with its accompanying bodily and cognitive strain on the performers. Stress in the operating room may lead to the onset of central serous chorioretinopathy as reported hereby in a retina surgeon and is labeled as operating room central serous chorioretinopathy. Methods: The same operator performed the optical coherence tomography scans on one retina surgeon. A masked observer estimated the maximal height of the subretinal fluid...
2017: SAGE Open Medical Case Reports
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