keyword
MENU ▼
Read by QxMD icon Read
search

Hepatitis b vaccine

keyword
https://www.readbyqxmd.com/read/27920392/knowledge-attitudes-and-practices-of-health-care-workers-about-viral-hepatitis-b-and-c-in-south-kivu
#1
Tony Akilimali Shindano, Esto Bahizire, René Fiasse, Yves Horsmans
Health-care workers (HCWs) are at risk of infections associated with accidental exposure to blood, including viral hepatitis B (HBV) and C (HCV). A survey using a questionnaire was conducted on 250 HCW in Bukavu, an eastern town of the Democratic Republic of Congo, to analyze their attitude and knowledge about these two viruses. A response rate of 86.8% (217/250) was obtained. The mean age of respondents was 39.6 ± 9.8 years, in majority from paramedical staff (66.4%) and with more than 5 years of professional experience (60...
December 5, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27917363/future-therapy-for-hepatitis-b-virus-role-of-immunomodulators
#2
REVIEW
Edward A Pham, Ryan B Perumpail, Benjamin J Fram, Jeffrey S Glenn, Aijaz Ahmed, Robert G Gish
Although currently available therapies for chronic hepatitis B virus infection can suppress viremia and provide long-term benefits for patients, they do not lead to a functional cure for most patients. Advances in our understanding of the virus-host interaction and the recent remarkable success of immunotherapy in cancer offer new and promising strategies for developing immune modulators that may become important components of a total therapeutic approach to hepatitis B, some of which are now in clinical development...
2016: Current Hepatology Reports
https://www.readbyqxmd.com/read/27917091/vaccinating-patients-with-inflammatory-bowel-disease
#3
Jason Reich, Sharmeel Wasan, Francis A Farraye
Patients with inflammatory bowel disease (IBD) are not vaccinated at the same rate as general medical patients. IBD places patients at increased risk for developing vaccine-preventable illnesses, and this risk is further exacerbated by immunosuppressive therapy. Therefore, gastroenterologists should familiarize themselves with health maintenance measures pertaining to patients with IBD. This article highlights the vaccinations required for patients with IBD, especially those who are immunosuppressed: influenza; pneumococcal pneumonia; hepatitis A and B viruses; human papilloma virus; meningococcal disease; tetanus, diphtheria, and pertussis; measles, mumps, and rubella; varicella zoster; and herpes zoster...
September 2016: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27911488/hepatocellular-carcinoma-as-an-emerging-morbidity-in-the-thalassemia-syndromes-a-comprehensive-review
#4
REVIEW
Hassan M Moukhadder, Racha Halawi, Maria Domenica Cappellini, Ali T Taher
The incidence of hepatocellular carcinoma (HCC) in patients with thalassemia is on the rise. The 2 well recognized HCC risk factors in thalassemia are iron overload and chronic viral infection with hepatitis C. The carcinogenicity of iron is related to its induction of oxidative damage, which results in genotoxicity, and to immunologic dysregulation, which attenuates cancer immune surveillance. Chronic hepatitis B and C infections lead to necroinflammation, which can prompt progression to HCC, but an independent role of hepatitis B virus in hepatic carcinogenesis among patients with thalassemia has not been demonstrated...
December 1, 2016: Cancer
https://www.readbyqxmd.com/read/27907975/-is-it-necessary-to-revaccinate-against-hepatitis-b-virus-when-the-titer-of-anti-hbs-drops-below-10-iu-l
#5
Pavel Polák, Petr Husa, Petr Smejkal, Jan Kamelander, Gabriela Chlupová, Miroslav Penka
Viral hepatitis B still represents a major epidemiological issue worldwide. After recombinant vaccine administration, a titer of anti-HBs antibodies ≥ 10 IU/L has long been considered to be seroprotective. Persons without this antibody level after complete vaccination are referred to as non-responders. A progressive decline in anti-HBs levels over years is also commonly seen in responders. Recently, there has been increasing evidence that the titer of anti-HBs ≥ 10 IU/L does not provide 100 % protection against infection and clinically manifest illness...
September 2016: Klinická Mikrobiologie a Infekc̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27905837/long-term-persistence-of-immunity-after-hepatitis-b-vaccination-a-fact-not-a-fancy
#6
Andrea Trevisan
On the basis of an article previously published in the journal regarding immune persistence after hepatitis B vaccination in infancy, I discuss why this persistence is a fact and not a fancy. Immune memory after a primary vaccination series has been widely demonstrated by prompt response to booster doses and the proliferation of T cells secreting IFNγ. In a large cohort of medical students, 79% of subjects were positive for anti-HBs antibodies, and only 1.9% of the subjects had serological evidence of past hepatitis B infection...
December 1, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27905821/effects-of-hepatitis-b-vaccine-boosters-on-anti-hbs-negative-children-after-primary-immunization
#7
Shunshun Lu, Jingjing Ren, Qian Li, Zhenggang Jiang, Yongdi Chen, Kaijin Xu, Bing Ruan, Shigui Yang, Tiansheng Xie, Linna Yang, Jing Li, Jun Yao
This study was aimed at evaluating the changes of hepatitis B surface antibody (anti-HBs) titer after booster vaccinations in 5-15-year-old children with negative antibodies (< 10 mIU/mL). 225 subjects (mean age, 9.28 ± 2.95 years) included in the study consisted of 123 males and 102 females, with a complete hepatitis B vaccination during infancy. The participants were divided into three groups according to their pre-booster anti-HBs level: Group I, < 0.1 mIU/mL; Group II, 0.1 to < 1.0 mIU/mL; Group III, 1...
December 1, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27905089/novel-paradigm-for-immunotherapy-of-ovarian-cancer-by-engaging-prophylactic-immunity-against-hepatitis-b-virus
#8
Marek Malecki, Emily Putzer, Caroline Quach, Chaitanya Dodivenaka, Xenia Tombokan
BACKGROUND: Only eight women out of one hundred diagnosed with ovarian epithelial cancers, which progressed to the clinical stage IV, survive 10 years. First line therapies: surgery, chemotherapy, and radiation therapy inflict very serious iatrogenic consequences. Passive immunotherapy of ovarian cancers offers only low efficacy. Prophylactic and therapeutic vaccines for ovarian cancers are not available. Interestingly, prophylactic vaccines for Hepatitis B Viruses (HBV) are very effective...
December 2016: Clinical and Translational Medicine
https://www.readbyqxmd.com/read/27898721/hepatitis-b-virus-infections-and-associated-factors-among-pregnant-women-attending-antenatal-care-clinic-at-deder-hospital-eastern-ethiopia
#9
Abdi Umare, Berhanu Seyoum, Tesfaye Gobena, Tamirat Haile Mariyam
BACKGROUND: Hepatitis B virus (HBV) infection is a serious public health problem worldwide. Reports have shown that 68,600 people die of HBV infection and more than 300,000 deaths due to liver cancer secondary to hepatitis B every year globally. Women who are infected with HBV can vertically transmit the infection to their infants. This study aims to determine the prevalence of HBV infection and associated factors among pregnant women. METHODS AND FINDINGS: A hospital-based cross-sectional study was conducted among pregnant women who attended antenatal care clinic (ANC) for routine pregnancy check-up between 18 March 2015 and 15 May 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27894721/vaccination-against-hepatitis-b-virus-among-people-who-inject-drugs-a-20year-experience-from-a-swedish-needle-exchange-program
#10
M Alanko Blomé, P Björkman, L Flamholc, H Jacobsson, A Widell
BACKGROUND: People who inject drugs (PWID) are at particular risk of hepatitis B virus (HBV) acquisition, but often have poor access or adherence to HBV vaccination. Vaccination against HBV has been offered at a major Swedish needle exchange program (NEP) since 1994. The aim of this study was to evaluate vaccine completion and response rates, and the effect of sequential booster doses to non-responders to the standard vaccination schedule. METHODS: PWID enrolled in the NEP 1994-2013, without serological markers for HBV at baseline (negative for HBsAg/anti-HBc/anti-HBs), were offered a three-dose standard intramuscular vaccination schedule (Engerix®-B, GSK, 20μg/mL, intended to be received at months 0, 1 and 6)...
November 25, 2016: Vaccine
https://www.readbyqxmd.com/read/27894717/hepatitis-b-vaccine-alone-may-be-enough-for-preventing-hepatitis-b-virus-transmission-in-neonates-of-hbsag-hbeag-mothers
#11
Ying Lu, Xiao-Feng Liang, Fu-Zhen Wang, Ling Yan, Rong-Cheng Li, Yan-Ping Li, Feng-Cai Zhu, Xiang-Jun Zhai, Jie Li, Hui Zhuang
BACKGROUND AND AIM: To prospectively evaluate the efficacy of vaccine alone compared with vaccine plus HBIG for preventing HBV transmission in neonates of HBsAg (+)/HBeAg (-) mothers. METHODS: Combined immunization is currently recommended for neonates of HBsAg (+) mothers in China. As a result, a randomized design is infeasible due to ethical reasons. In practice, Guangxi Zhuang Autonomous Region and Jiangsu Province implement vaccine alone and vaccine plus HBIG strategies for neonates born to HBsAg (+)/HBeAg (-) mothers, respectively...
November 25, 2016: Vaccine
https://www.readbyqxmd.com/read/27892847/international-adoption-from-ethiopia-an-overview-of-the-health-status-at-arrival-in-belgium
#12
Lydia Van Kesteren, Marek Wojciechowski
BACKGROUND: Ethiopia is a densely populated country with a fast growing economy. Still socioeconomic and health issues render many children parentless. One thousand and twenty eight Ethiopian children have been adopted in Belgium from September 2005 to September 2015. Little has been published about their health status at arrival. METHODS: Three hundred and fifteen children adopted from Ethiopia were clinically evaluated at the Institute of Tropical Medicine in Antwerp from 1 January 2008 until 31 December 2014...
November 28, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27892722/present-and-future-dna-vaccines-for-chronic-hepatitis-b-treatment
#13
Lucyna Cova
With at least 240 million hepatitis B virus (HBV) carriers worldwide, being at a high risk of cirrhosis and hepatocellular carcinoma (HCC), chronic hepatitis B remains a major public health issue. Because current antiviral treatments are only virostatic, there is an urgent need for the development of innovative anti-HBV strategies leading to the functional cure. In this context, DNA-based vaccines appear as a promising approach. Area covered: In this review, the authors summarize the pertinent features of DNA vaccines for chronic hepatitis B therapy...
November 28, 2016: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/27890663/hepatitis-b-a-cross-sectional-survey-of-knowledge-attitudes-and-practices-amongst-backpackers-in-thailand
#14
Georgina Frew, Elizabeth McGeorge, Sabrina Grant, Gilles de Wildt
BACKGROUND: In 2013, 200 million tourists visited countries that are endemic for hepatitis B virus (HBV). Backpackers are potentially at greater risk of hepatitis B than other travellers yet exposure to HBV remains under researched in this population. METHOD: A cross-sectional survey of backpackers visiting two islands in Thailand was performed during early 2015. Participation in activities with high HBV exposure risk was recorded, alongside rates of vaccination and an evaluation of knowledge and attitudes towards the risk of HBV...
November 23, 2016: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/27889711/immunogenicity-and-safety-of-a-liquid-hexavalent-vaccine-in-indian-infants
#15
Jugesh Chhatwal, Sanjay Lalwani, Emmanuel Vidor
OBJECTIVE: To evaluate the immunogenicity and safety of a fully liquid, hexavalent diphtheria tetanus acellular pertussis inactivated poliovirus hepatitis B Haemophilus influenzae type b (DTaP IPV HB PRPT) vaccine in Indian infants. DESIGN: Phase III, single-arm study. SETTING: Two tertiary care hospitals. PARTICIPANTS: 177 healthy, 6-week-old infants. INTERVENTION: All participants received HB and OPV vaccines at birth and DTaP-IPV-HB-PRP~T at 6, 10, 14 weeks of age...
November 5, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27887796/vaccine-strategies-optimising-outcomes
#16
Karin Hardt, Paolo Bonanni, Susan King, Jose Ignacio Santos, Mostafa El-Hodhod, Gregory D Zimet, Scott Preiss
Successful immunisation programmes generally result from high vaccine effectiveness and adequate uptake of vaccines. In the development of new vaccination strategies, the structure and strength of the local healthcare system is a key consideration. In high income countries, existing infrastructures are usually used, while in less developed countries, the capacity for introducing new vaccines may need to be strengthened, particularly for vaccines administered beyond early childhood, such as the measles or human papillomavirus (HPV) vaccine...
November 22, 2016: Vaccine
https://www.readbyqxmd.com/read/27885748/protective-efficacy-and-hepatitis-b-virus-clearance-in-mice-enhanced-by-cell-mediated-immunity-with-novel-prime-boost-regimens
#17
X Chuai, P Chen, H Chen, W Wang, Y Deng, L Ruan, W Li, W Tan
In this study, anti-hepatitis B virus (HBV) immunity was evaluated in mice using several regimens of the HBV recombinant protein vaccine HBSS1 that expressed in CHO cells containing S (1-223 aa) and preS1 (21-47 aa) and recombinant adenovirus rAdSS1 vaccine. Further, the protective efficacy of these vaccine regimens was studied in a mouse model. High titres of antigen-specific antibodies and neutralizing activity were elicited in mice after vaccination. However, robust multi-antigen (preS1 and S)-specific cell-mediated immunity (CMI) was only detected in mice primed with HBSS1 and boosted with rAdSS1...
November 25, 2016: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/27875529/cd4-t-cells-are-as-protective-as-cd8-t-cells-against-rickettsia-typhi-infection-by-activating-macrophage-bactericidal-activity
#18
Kristin Moderzynski, Stefanie Papp, Jessica Rauch, Liza Heine, Svenja Kuehl, Ulricke Richardt, Bernhard Fleischer, Anke Osterloh
Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C57BL/6 RAG1-/- mice upon Rickettsia typhi infection. Here, we show that CD4+ TH1 cells that are generated in C57BL/6 mice upon R. typhi infection are as protective as cytotoxic CD8+ T cells. CD4+- as well as CD8+-deficient C57BL/6 survived the infection without showing symptoms of disease at any point in time...
November 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27874311/long-term-persistence-in-protection-and-response-to-a-hepatitis-b-vaccine-booster-among-adolescents-immunized-in-infancy-in-the-western-region-of-china
#19
Zhen-Zi Wang, Yu-Hua Gao, Wei Lu, Cun-Duo Jin, Ying Zeng, Ling Yan, Feng Ding, Tong Li, Xue-En Liu, Hui Zhuang
OBJECTIVES: To evaluate the persistence of protection from hepatitis B (HB) vaccination among adolescents immunized with a primary series of HB vaccine as infants, and the immune response to booster doses. METHODS: Healthy adolescents aged 15-17 years vaccinated with HB vaccine only at birth were enrolled. Baseline serum hepatitis B surface antigen (HBsAg), antibody against hepatitis B surface antigen (anti-HBs) and antibody against hepatitis B core antigen (anti-HBc) were detected by Enzyme-Linked Immunosorbent Assay (ELISA) and anti-HBs level was measured using Chemiluminescent Microparticle Immunoassay (CMIA)...
November 22, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27866773/influenza-h7n9-lah-hbc-virus-like-particle-vaccine-with-adjuvant-protects-mice-against-homologous-and-heterologous-influenza-viruses
#20
Dan Zheng, Shaoheng Chen, Di Qu, Jianjun Chen, Fuyan Wang, Ran Zhang, Ze Chen
The long alpha-helix (LAH) region located in influenza virus hemagglutinin (HA) shows conservation among different influenza A strains, which could be used as a candidate target of influenza vaccines. Moreover, the hepatitis B virus core protein (HBc) is a carrier for heterologous epitopes in eliciting effective immune responses. We inserted the LAH region of H7N9 influenza virus into the HBc and prepared the LAH-HBc protein, which were capable of self-assembly into virus-like particles (VLP), by using E. coli expression system...
December 12, 2016: Vaccine
keyword
keyword
10777
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"