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osteoporotic fractures

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https://www.readbyqxmd.com/read/28445294/unilateral-versus-bilateral-percutaneous-kyphoplasty-for-osteoporotic-vertebral-compression-fractures-a-meta-analysis
#1
Wenli Chang, Xinyan Zhang, Ning Jiao, Peizhi Yuwen, Yanbin Zhu, Fei Zhang, Wei Chen
BACKGROUND: The debate on the efficacy of unilateral percutaneous kyphoplasty (UPKP) and bilateral percutaneous kyphoplasty (BPKP) for the treatment of osteoporotic vertebral compression fractures (OVCFs) is ongoing.This meta-analysis aimed to evaluate the clinical results of UPKP and BPKP in the treatment of OVCFs. METHODS: Web of Science, PubMed, Embase, and the Chinese Biomedical Database publication databases were searched using a date range of January 2008 to November 2016, for studies comparing UPKP and BPKP for the treatment of OVCFs...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28444483/exploring-racial-gender-and-insurance-disparities-in-patients-with-osteoporotic-fractures
#2
Sarah C DeShields, Cynthia C Romero, Tina D Cunningham
The objective of this study is to examine racial, gender, and insurance disparities in hospital outcomes among patients diagnosed with osteoporotic fractures aged 55 years and older. A total of 36,153 patients were included in this study. The sample was constructed from de-identified patient-level data for 2011 through 2014 from the Virginia Health Information (VHI) inpatient discharge database. Differences in mortality and 30-day readmission across race, gender, and insurance status were examined using logistic regression and generalized linear models for hospital charges and length of stay...
April 25, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28444431/spinal-radiographs-in-those-with-back-pain-when-are-they-appropriate-to-diagnose-vertebral-fractures
#3
REVIEW
E M Clark, S R Cummings, J T Schousboe
The presence of an osteoporotic vertebral fracture improves fracture risk assessment and may change management, so it is vital for healthcare professionals to assess patients for the presence or absence of these fractures. This may be particularly important in the presence of back pain. However, the correlation between low back symptoms and spinal imaging results is poor and the pathophysiology of most low back pain is not known, leading to a common conclusion that spinal radiographs are not appropriate for the assessment of back pain...
April 25, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28441542/reattachment-using-the-suture-bridge-augmentation-for-achilles-tendon-avulsion-fracture-with-osteoporotic-bony-fragment
#4
Byung-Ki Cho, Ji-Kang Park, Seung-Myung Choi
Although avulsion fractures of the calcaneal tuberosity are rare injuries, these can be a challenging problem with frequent complications, such as loss of reduction and soft tissue problem. Anatomical reduction and internal fixation are indicated to avoid these pitfalls and to restore function of the triceps surae. However, the best fixation device and operative technique are still controversial. A case that achieved satisfactory clinical outcome through a reattachment technique using the suture bridge augmentation for Achilles tendon avulsion fracture with osteoporotic bony fragment is presented...
April 15, 2017: Foot
https://www.readbyqxmd.com/read/28439056/-calcium-and-bone-metabolism-across-women-s-life-stages-treatment-for-the-malignant-tumors-in-women-and-bone-calcium-metabolism
#5
Noriko Kobayashi
In the malignant tumors in women, uterine cervical cancer, endometrial cancer, ovarian cancer, and breast cancer are representative diseases. The cancer treatment is classified roughly into an operation, medical treatment, and radiation therapy and has an extremely big influence on ovarian function. With the improvement in survival of cancer patients, the importance of the health care for the cancer survivors increases. It is necessary to prevent the onset of the osteoporotic fractures to maintain QOL. This paper describes the action that the malignant tumors of the women affect bone metabolism mainly from the viewpoint of ovarian function...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28435906/low-back-pain-in-older-adults-risk-factors-management-options-and-future-directions
#6
REVIEW
Arnold Yl Wong, Jaro Karppinen, Dino Samartzis
Low back pain (LBP) is one of the major disabling health conditions among older adults aged 60 years or older. While most causes of LBP among older adults are non-specific and self-limiting, seniors are prone to develop certain LBP pathologies and/or chronic LBP given their age-related physical and psychosocial changes. Unfortunately, no review has previously summarized/discussed various factors that may affect the effective LBP management among older adults. Accordingly, the objectives of the current narrative review were to comprehensively summarize common causes and risk factors (modifiable and non-modifiable) of developing severe/chronic LBP in older adults, to highlight specific issues in assessing and treating seniors with LBP, and to discuss future research directions...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28434032/diabetes-bone-and-glucose-lowering-agents-basic-biology
#7
REVIEW
Beata Lecka-Czernik
Skeletal fragility often accompanies diabetes and does not appear to correlate with low bone mass or trauma severity in individuals with diabetes. Instead (and in contrast to those with osteoporotic bone disease), bone remodelling and bone turnover are compromised in both type 1 and type 2 diabetes, contributing to defective bone material quality. This review is one of a pair discussing the relationship between diabetes, bone and glucose-lowering agents; an accompanying review is provided in this issue of Diabetologia by Ann Schwartz (DOI: 10...
April 22, 2017: Diabetologia
https://www.readbyqxmd.com/read/28432379/high-resolution-tomography-based-quantification-of-cortical-porosity-and-cortical-thickness-at-the-surgical-neck-of-the-humerus-during-aging
#8
Tobias Helfen, Christoph M Sprecher, Ursula Eberli, Boyko Gueorguiev, Peter E Müller, Robert G Richards, Florian Schmidutz
Fractures of the proximal humerus are highly related to age and osteoporotic bone remodeling. Previous studies have highlighted the cortex as a major side of the bone loss, but the microstructural changes of the humerus have not been evaluated entirely. Sixty-four (n = 64) humeri of a representative collective (18-100 years) were scanned with high-resolution peripheral quantitative computed tomography (82 µm). Bone mineral density (BMD), trabecular bone volume fraction (Tb.BV/TV), cortical thickness (Ct...
April 21, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28429363/two-unilateral-puncturation-comparative-analyses-of-multiple-level-fresh-osteoporotic-vertebral-body-compression-fractures-treated-with-percutaneous-vertebroplasty-guided-by-c-arm-fluoroscopy-or-in-senile-patients
#9
J-C Xu, G-H Wu, L-L Zhou, X-J Yang, J-T Liu
OBJECTIVE:  To compare the curative effects of two unilateral puncturation percutaneous vertebroplasty (PVP) for the pain caused by multiple-level osteoporotic vertebral body compression fractures (OVCF) in senile patients. PATIENTS AND METHODS: From June 2008 to November 2014, eighty-nine cases suffering from fresh multiple-level OVCF were randomly divided into experimental group (n=51) and control group (n=38). Patients underwent PVP guided by C-arm fluoroscopy in the prone position...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28429247/a-review-of-the-novel-application-and-potential-adverse-effects-of-proton-pump-inhibitors
#10
REVIEW
Li-Yuan Yu, Lu-Ning Sun, Xue-Hui Zhang, Yue-Qi Li, Lei Yu, Zi-Qing-Yun Yuan, Ling Meng, Hong-Wen Zhang, Yong-Qing Wang
Proton pump inhibitors (PPIs) are known as a class of pharmaceutical agents that target H(+)/K(+)-ATPase, which is located in gastric parietal cells. PPIs are widely used in the treatment of gastric acid-related diseases including peptic ulcer disease, erosive esophagitis and gastroesophageal reflux disease, and so on. These drugs present an excellent safety profile and have become one of the most commonly prescribed drugs in primary and specialty care. Except for gastric acid-related diseases, PPIs can also be used in the treatment of Helicobacter pylori infection, viral infections, respiratory system diseases, cancer and so on...
April 20, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28428829/semivariogram-analysis-of-bone-images-implemented-on-fpga-architectures
#11
Mukul Shirvaikar, Yamuna Lagadapati, Xuanliang Dong
Osteoporotic fractures are a major concern for the healthcare of elderly and female populations. Early diagnosis of patients with a high risk of osteoporotic fractures can be enhanced by introducing second-order statistical analysis of bone image data using techniques such as variogram analysis. Such analysis is computationally intensive thereby creating an impediment for introduction into imaging machines found in common clinical settings. This paper investigates the fast implementation of the semivariogram algorithm, which has been proven to be effective in modeling bone strength, and should be of interest to readers in the areas of computer-aided diagnosis and quantitative image analysis...
March 2017: J Real Time Image Process
https://www.readbyqxmd.com/read/28428645/effect-of-tailored-educational-intervention-to-improve-self-care-maintenance-and-quality-of-life-in-postmenopausal-osteoporotic-women-after-a-fragility-fracture-the-guardian-angel-reg-study
#12
Emanuela Basilici Zannetti, Fabio D'Agostino, Noemi Cittadini, Maurizio Feola, Annalisa Pennini, Cecilia Rao, Ercole Vellone, Umberto Tarantino, Rosaria Alvaro
Osteoporosis has a significant impact on affected patients. Healthcare providers should encourage postmenopausal women to improve self-care maintenance behaviors and quality of life following a fragility fracture. The aims of this study were to a) develop two new instruments for measuring, respectively, self-care maintenance and quality of life, in postmenopausal women with osteoporosis; b) evaluate the effectiveness of a tailored educational intervention to improve self-care maintenance and quality of life after a fragility fracture in postmenopausal women...
January 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28426535/frailty-in-hiv-infected-people-a-new-risk-factor-for-bone-mineral-density-loss
#13
Sylvie Bregigeon, Anne Galinier, Olivia Zaegel-Faucher, Carla E Cano, Véronique Obry, Hélène Laroche, Sophie Trijau, Armelle Saout, Isabelle Poizot-Martin
OBJECTIVE: This study aims to assess the association between bone mineral density (BMD) and frailty in a cohort of HIV-infected patients. DESIGN: A cross-sectional study in an HIV outpatient unit where nearly 1,000 patients are monitored. METHODS: Subjects undergoing bone densitometry were proposed an evaluation of frailty using criteria of the Cardiovascular Health Study (CHS) and the Study of Osteoporotic Fractures (SOF). Frailty markers (FM) were weight-loss, self-reported exhaustion, physical activity, grip strength, chair stands, and slow gait...
April 19, 2017: AIDS
https://www.readbyqxmd.com/read/28423154/association-of-mental-disorders-and-related-medication-use-with-risk-for-major-osteoporotic-fractures
#14
James M Bolton, Suzanne N Morin, Sumit R Majumdar, Jitender Sareen, Lisa M Lix, Helena Johansson, Anders Odén, Eugene V McCloskey, John A Kanis, William D Leslie
Importance: Osteoporotic fractures are a leading cause of disability, costs, and mortality. FRAX is a tool used to assess fracture risk in the general population. Mental disorders and medications to treat them have been reported to adversely affect bone health, but, to date, they have not been systematically studied in relation to osteoporotic fractures. Objective: To examine the association of mental disorders and psychotropic medication use with osteoporotic fracture risk in routine clinical practice...
April 19, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28422544/effects-of-balance-coordination-strengthening-and-aerobic-exercises-to-prevent-falls-in-postmenopausal-patients-with-osteoporosis-a-6-month-randomized-parallel-prospective-study
#15
Meltem Dizdar, Jale Fatma Irdesel, Oguzhan Sıtkı Dizdar, Mine Topsac
Osteoporosis is a systemic disease characterized by the increase of bone fragility and fracture risk. Postmenopausal female osteoporotic patients were randomized into 3 groups;balance and coordination, strengthening, and aerobic exercise group. The exercise programs were performed for 12 weeks, one hour each day for three days of the week.Patients were followed-up for 12 weeks after the initial intervention. After the exercise program, patients continued their daily life activities and were called back to the clinic for additional testing after 12 weeks...
April 19, 2017: Journal of Aging and Physical Activity
https://www.readbyqxmd.com/read/28422273/a-survey-of-women-s-awareness-of-and-reasons-for-lack-of-postfracture-osteoporotic-care
#16
Denise M Boudreau, Onchee Yu, Akhila Balasubramanian, Heidi Wirtz, Andreas Grauer, Daria B Crittenden, Delia Scholes
OBJECTIVES: To identify women's beliefs and other factors associated with lack of osteoporosis (OP) pharmacotherapy (OP-RX) during the 6 months after a fragility fracture, including the woman's perspective on fracture risk, OP, and treatment. DESIGN: Cross-sectional. SETTING: Group Health Cooperative, a mixed-model delivery system. PARTICIPANTS: Female Group Health Cooperative enrollees aged 55 and older with an OP-related fracture according to diagnostic and procedure codes from January 1, 2013, to March 30, 2014 (N = 985)...
April 19, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28420922/relationship-of-anthropometric-measures-with-bone-mineral-density-in-postmenopausal-non-osteoporotic-osteopenic-and-osteoporotic-women
#17
Sundus Tariq, Saba Tariq, Khalid Parvez Lone
Background and objectives: Body mass index (BMI) has been shown to be a more important predictor of bone mineral density (BMD). The objective of this study was to investigate the relationship of anthropometric measures including body mass index with bone mineral density in postmenopausal non-osteoporotic, osteopenic and osteoporotic women. METHODS: In this cross sectional study postmenopausal females between 50-70 years of age were recruited and divided into three groups: non-osteoporotic (n=52), osteopenic (n=69) and osteoporotic females (n=47)...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28417681/proximal-femoral-nail-antirotation-versus-dynamic-hip-screw-fixation-for-treatment-of-osteoporotic-type-31-a1-intertrochanteric-femoral-fractures-in-elderly-patients
#18
Xianshang Zeng, Nan Zhang, Dan Zeng, Lili Zhang, Ping Xu, Lei Cao, Weiguang Yu, Ke Zhan, Xinchao Zhang
Objective To evaluate long-term radiographic and functional outcomes between dynamic hip screw (DHS) and proximal femoral nail antirotation (PFNA) fixation for treatment of osteoporotic type 31-A1 intertrochanteric femoral fractures (IFFs) among elderly patients Methods A retrospective comparative study was carried out. Follow-up was performed at 1, 3, 6, 9, and 12 months postoperatively and yearly thereafter. The primary outcome was the radiographic outcome, and the secondary outcome was the functional outcome...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28416837/-clinical-comparison-of-polymethylmethacrylate-and-bone-cement-in-the-treatment-of-osteoporotic-vertebral-compression-fractures-a-retrospective-study
#19
L P Shang, Y Tian, X G Liu
OBJECTIVE: To analyze the outcomes of patients with osteoporotic vertebral compression fractures treated with polymethylmethacrylate (PMMA) and GeneX bone cement in percutaneous kyphoplasty and to provide guidance in selecting the vertebral filling material for this procedure. METHODS: In this study, 86 patients with osteoporotic vertebral compression fractures treated at Peking University Third Hospital between June 2012 and June 2013 were retrospectively analyzed...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28411093/association-between-diet-inflammatory-index-and-osteoporotic-hip-fracture-in-elderly-chinese-population
#20
Zhe-Qing Zhang, Wen-Ting Cao, Nitin Shivappa, James R Hebert, Bao-Lin Li, Juan He, Xin-Yi Tang, Ya-Yong Liang, Yu-Ming Chen
BACKGROUND: Chronic inflammation provides the substrate for various mechanisms involved in osteoporotic fracture. The Dietary Inflammatory Index (DII) could shed light on the effect of the inflammatory potential of the diet on osteoporotic hip fracture. OBJECTIVE: This study tested the hypothesis that higher DII scores are associated with greater hip fracture risk in an elderly Chinese population. METHODS: A 1:1 age- (±3 years), sex- and region-matched case-control study of 1050 pairs (female/male: 781/269) of elderly (age range = 52-83 years) Chinese was conducted in Guangdong, China (2009-2015)...
April 11, 2017: Journal of the American Medical Directors Association
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