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https://www.readbyqxmd.com/read/27920947/the-daniel-k-inouye-college-of-pharmacy-scripts-poha-berry-physalis-peruviana-with-potential-anti-inflammatory-and-cancer-prevention-activities
#1
Leng Chee Chang, Mayuramas Sang-Ngern, John M Pezzuto, Carolyn Ma
The Daniel K. Inouye College of Pharmacy, during a historic event in Spring 2016, graduated the first two students in the Pacific region to earn a PhD in pharmaceutical sciences at the University of Hawai'i at Hilo. The college offers PhD programs in these five disciplines: Cancer Biology, Medicinal Chemistry, Pharmaceutics, Pharmacognosy, and Pharmacology. One of the Pharmacognosy dissertations focused on plant-derived natural products with potential anti-inflammatory and cancer chemopreventive activities...
November 2016: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/27865796/bletilla-striata-medicinal-uses-phytochemistry-and-pharmacological-activities
#2
REVIEW
Xirui He, Jiacheng Fang, Xiaoxiao Wang, Zefeng Zhao, Yu Chang, Hao Guo, Linhong Huang
ETHNOPHARMACOLOGICAL RELEVANCE: Bletilla striata (Thunb.) Reichb. f. (Orchidaceae), also known as Hyacinth Orchid and Baiji (Simplified Chinese: ), not only has been widely used for the treatment of hematemesis, hemoptysis, and traumatic bleeding due to the efficacy of arresting bleeding with astringent action, but also has been applied topically to overcome ulcers, sores, swellings, and chapped skin due to the efficacy of dispersing swelling and promoting tissue regeneration. Additional medical applications include the treatment of tuberculosis, malignant ulcers, hemorrhoids, anthrax, eye diseases, and silicosis...
November 16, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27529826/non-pharmacological-interventions-for-cognitive-impairment-due-to-systemic-cancer-treatment
#3
REVIEW
Charlene J Treanor, Una C McMenamin, Roisin F O'Neill, Chris R Cardwell, Mike J Clarke, Marie Cantwell, Michael Donnelly
BACKGROUND: It is estimated that up to 75% of cancer survivors may experience cognitive impairment as a result of cancer treatment and given the increasing size of the cancer survivor population, the number of affected people is set to rise considerably in coming years. There is a need, therefore, to identify effective, non-pharmacological interventions for maintaining cognitive function or ameliorating cognitive impairment among people with a previous cancer diagnosis. OBJECTIVES: To evaluate the cognitive effects, non-cognitive effects, duration and safety of non-pharmacological interventions among cancer patients targeted at maintaining cognitive function or ameliorating cognitive impairment as a result of cancer or receipt of systemic cancer treatment (i...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27402192/polyphenol-based-nutraceuticals-for-the-control-of-angiogenesis-analysis-of-the-critical-issues-for-human-use
#4
REVIEW
Lucia Morbidelli
Angiogenesis, the formation of new blood-vessel, is crucial in the pathogenesis of several diseases, and thus represents a druggable target for the prevention and treatment of different disorders. It is nowadays well kwon how diet can control cancer development and progression, and how the use of certain diet components can prevent cancer development. Several studies, also from our lab, now indicate that natural plant products including nutraceuticals modulate tumor angiogenesis. In this review, it is reported how phytochemicals, comprising hydroxytyrosol, resveratrol, genistein, curcumin, and the green tea component epigallocatechin-3-gallate among the others, negatively regulate angiogenesis...
September 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27320046/emblica-officinalis-amla-a-review-for-its-phytochemistry-ethnomedicinal-uses-and-medicinal-potentials-with-respect-to-molecular-mechanisms
#5
REVIEW
Bhavesh C Variya, Anita K Bakrania, Snehal S Patel
Medicinal plants, having great elementary and therapeutic importance, are the gift to mankind to acquire healthy lifestyle. Emblica officinalis Gaertn. or Phyllanthus emblica Linn. (Euphorbeaceae), commonly known as Indian gooseberry or Amla, has superior value in entirely indigenous traditional system of medicine, including folklore Ayurveda, for medicinal and nutritional purposes to build up lost vitality and vigor. In this article, numerous phytochemicals isolated from E. officinalis and its ethnomedical and pharmacological potentials with molecular mechanisms are briefly deliberated and recapitulated...
September 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27085938/local-and-traditional-uses-phytochemistry-and-pharmacology-of-sophora-japonica-l-a-review
#6
REVIEW
Xirui He, Yajun Bai, Zefeng Zhao, Xiaoxiao Wang, Jiacheng Fang, Linhong Huang, Min Zeng, Qiang Zhang, Yajun Zhang, Xiaohui Zheng
ETHNOPHARMACOLOGICAL RELEVANCE: Sophora japonica (Fabaceae), also known as Huai (Chinese: ), is a medium-sized deciduous tree commonly found in China, Japan, Korea, Vietnam, and other countries. The use of this plant has been recorded in classical medicinal treatises of ancient China, and it is currently recorded in both the Chinese Pharmacopoeia and European Pharmacopoeia. The flower buds and fruits of S. japonica, also known as Flos Sophorae Immaturus and Fructus Sophorae in China, are most commonly used in Asia (especially in China) to treat hemorrhoids, hematochezia, hematuria, hematemesis, hemorrhinia, uterine or intestinal hemorrhage, arteriosclerosis, headache, hypertension, dysentery, dizziness, and pyoderma...
July 1, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26844923/ethnomedicinal-uses-phytochemistry-and-pharmacological-properties-of-the-genus-boerhavia
#7
REVIEW
Kapil S Patil, Sanjivani R Bhalsing
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Boerhavia is widely distributed in tropical, subtropical and temperate regions of the world including Mexico, America, Africa, Asia, Indian Ocean Islands, Pacific Islands and Australia. The genus Boerhavia is extensively used by local peoples and medicinal practitioners for treatments of hepatitis, urinary disorders, gastro intestinal diseases, inflammations, skin problems, infectious diseases and asthma. Present review focused on traditional uses, phytochemistry, pharmacology and toxicology of Boerhavia genus to support potential scope for advance ethnopharmacological study...
April 22, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26785128/ptyalism-in-pregnancy-a-review-of-epidemiology-and-practices
#8
REVIEW
Karen A Thaxter Nesbeth, Leslie A Samuels, Carla Nicholson Daley, Maxine Gossell-Williams, Damian A Nesbeth
Ptyalism gravidarum is an oral pathological condition specific to gravidity. We present a review of the literature regarding epidemiology internationally, and then highlight therapies reported by patients and caregivers. This often distressing repeated filling of the mouth with watery saliva in a pregnant patient was previously exclusively associated with hyperemesis gravidarum, and the consequent maternal-fetal risk. Our dissertation includes reference to a rare case of isolated sialorrhoea of pregnancy, without nausea or emesis...
March 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26718919/alkaloids-pharmacological-activities-prospects-for-the-development-of-phytopharmaceuticals-for-neurodegenerative-diseases
#9
Soane K M Chaves, Chistiane M Feitosa, Lidiane da S Araújo
The study of natural substances has increased in recent years in the search for compounds with pharmacological properties that can be used for the development of new drugs. The alkaloids, substances extracted natural sources, show promising pharmacological activities, including pharmacological activities for the treatment of neurodegenerative diseases such as Alzheimer's disease, whose treatment is based on the use of various drugs. Thus, the article aims to a technological prospecting of alkaloids that presented important properties in the treatment of neurodegenerative diseases, namely, antioxidant, anxiolytic, anti-inflammatory and antidepressant properties...
2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/26680589/ethnomedical-research-and-review-of-q-eqchi-maya-women-s-reproductive-health-in-the-lake-izabal-region-of-guatemala-past-present-and-future-prospects
#10
REVIEW
Joanna L Michel, Armando Caceres, Gail B Mahady
ETHNOPHARMACOLOGICAL RELEVANCE: In Central America, most Maya women use ethnomedicines for all aspects of their reproductive cycle including menstruation, pregnancy and menopause. However, very few of these plants have been documented, collected and tested in appropriate pharmacological assays to determine possible safety and efficacy. The aim of this work was to provide an overview of information on the ethnomedical uses, ethnopharmacology, chemistry and pharmacological research for medicinal plants used for women's reproductive health in Guatemala, with a special emphasis on the Q'eqchi Maya of the Lake Izabal region, to demonstrate therapeutic potential and support future research in the field...
February 3, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26680516/nicotine-lozenges-and-behavioural-interventions-may-help-smokeless-tobacco-users-to-quit
#11
Dominic Hurst
DATA SOURCES: Cochrane Central Register of Controlled trials (CENTRAL); Medline; Embase; PsycINFO. Additional sources were also searched for early versions of the review: Web of Science, Dissertation Abstracts Online, Scopus, Healthstar, ERIC, National Technical Information Service database and Current Contents. STUDY SELECTION: Randomised controlled trials and pseudo-randomised controlled trials allocating smokeless tobacco (ST) users to an intervention or control, or to different interventions...
December 2015: Evidence-based Dentistry
https://www.readbyqxmd.com/read/26471289/the-treatment-of-rheumatoid-arthritis-using-chinese-medicinal-plants-from-pharmacology-to-potential-molecular-mechanisms
#12
REVIEW
Shaowa Lü, Qiushi Wang, Guoyu Li, Shuang Sun, Yuyan Guo, Haixue Kuang
ETHNOPHARMACOLOGICAL RELEVANCE: Rheumatoid arthritis (RA) is a common worldwide public health problem. Traditional Chinese Medicine (TCM) achieved some results to some extent in the treatment of rheumatoid arthritis (RA). Especially in China, TCM formulas are used in the clinic because of their advantages. Some of these TCM formulas have been used for thousands of years in ancient China, they pays much attention to strengthening healthy qi, cleaning heat, and wet, activating blood, etc...
December 24, 2015: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26439374/non-pharmacological-interventions-for-sleep-promotion-in-the-intensive-care-unit
#13
REVIEW
Rong-Fang Hu, Xiao-Ying Jiang, Junmin Chen, Zhiyong Zeng, Xiao Y Chen, Yueping Li, Xin Huining, David J W Evans
BACKGROUND: Adults in intensive care units (ICUs) often suffer from a lack of sleep or frequent sleep disruptions. Non-pharmacological interventions can improve the duration and quality of sleep and decrease the risk of sleep disturbance, delirium, post-traumatic stress disorder (PTSD), and the length of stay in the ICU. However, there is no clear evidence of the effectiveness and harms of different non-pharmacological interventions for sleep promotion in adults admitted to the ICU. OBJECTIVES: To assess the efficacy of non-pharmacological interventions for sleep promotion in critically ill adults in the ICU...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26432351/medicinal-plants-of-the-genus-anthocleista-a-review-of-their-ethnobotany-phytochemistry-and-pharmacology
#14
REVIEW
Gabriel O Anyanwu, Nisar-ur-Rehman, Chukwu E Onyeneke, Khalid Rauf
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Anthocleista of the Gentianaceae family contains 14 species of trees and shrub-like plants distributed in tropical Africa, in Madagascar and on the Comoros. Traditionally, they are commonly used in the treatment of diabetes, hypertension, malaria, typhoid fever, obesity, diarrhea, dysentery, hyperprolactinemia, abdominal pain, ulcer, jaundice, asthma, hemorrhoids, hernia, cancer, wounds, chest pains, inflammations, rheumatism, STDs, infertility and skin diseases...
December 4, 2015: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26417202/impact-of-chronic-pain-on-treatment-prognosis-for-patients-with-opioid-use-disorder-a-systematic-review-and-meta-analysis
#15
REVIEW
Brittany B Dennis, Monica Bawor, Leen Naji, Carol K Chan, Jaymie Varenbut, James Paul, Michael Varenbut, Jeff Daiter, Carolyn Plater, Guillaume Pare, David C Marsh, Andrew Worster, Dipika Desai, Lehana Thabane, Zainab Samaan
BACKGROUND: While a number of pharmacological interventions exist for the treatment of opioid use disorder, evidence evaluating the effect of pain on substance use behavior, attrition rate, and physical or mental health among these therapies has not been well established. We aim to evaluate these effects using evidence gathered from a systematic review of studies evaluating chronic non-cancer pain (CNCP) in patients with opioid use disorder. METHODS: We searched the Medline, EMBASE, PubMed, PsycINFO, Web of Science, Cochrane Database of Systematic Reviews, ProQuest Dissertations and theses Database, Cochrane Central Register of Controlled Trials, World Health Organization International Clinical Trials Registry Platform Search Portal, and National Institutes for Health Clinical Trials Registry databases to identify articles evaluating the impact of pain on addiction treatment outcomes for patients maintained on opioid agonist therapy...
2015: Substance Abuse: Research and Treatment
https://www.readbyqxmd.com/read/26387740/the-medicinal-uses-of-the-genus-mahonia-in-traditional-chinese-medicine-an-ethnopharmacological-phytochemical-and-pharmacological-review
#16
REVIEW
Jian-Ming He, Qing Mu
ETHNOPHARMACOLOGICAL RELEVANCE: Plants of the genus Mahonia Nuttall (Berberidaceae) have a long history of medical use in Traditional Chinese Medicine (TCM) for the treatment of a wide range of health disorders, such as tuberculosis, periodontitis, dysentery, pharyngolaryngitis, eczema, and wounds. In the theory of TCM, most Mahonia species exert the effects of relieving internal heat, eliminating dampness, removing toxins, suppressing pain, promoting blood circulation, inhibiting cough and alleviating inflammation...
December 4, 2015: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26387487/interventions-for-preventing-postpartum-constipation
#17
REVIEW
Eunice B Turawa, Alfred Musekiwa, Anke C Rohwer
BACKGROUND: Postpartum constipation, with symptoms such as pain or discomfort, straining, and hard stool, is a common condition affecting mothers. Haemorrhoids, pain at the episiotomy site, effects of pregnancy hormones and haematinics used in pregnancy can increase the risk of postpartum constipation. Eating a high-fibre diet and increasing fluid intake is usually encouraged, although laxatives are commonly used in relieving constipation. The effectiveness and safety of available interventions for preventing postpartum constipation needs to be ascertained...
2015: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26384001/the-genus-rumex-review-of-traditional-uses-phytochemistry-and-pharmacology
#18
REVIEW
Andrea Vasas, Orsolya Orbán-Gyapai, Judit Hohmann
ETHNOPHARMACOLOGICAL RELEVANCE: The approximately 200 species of the genus Rumex (sorrel, Polygonaceae) are distributed worldwide (European, Asian, African and American countries). Some species have been used traditionally as vegetables and for their medicinal properties. Based on the traditional knowledge, different phytochemical and pharmacological activities have been at the focus of research. This review aims to provide an overview of the current state of knowledge of local and traditional medical uses, chemical constituents, pharmacological activities, toxicity, and safety of Rumex species, in order to identify the therapeutic potential of Rumex species and further directions of research...
December 4, 2015: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/26225717/hydroxytyrosol-derived-compounds-a-basis-for-the-creation-of-new-pharmacological-agents-for-cancer-prevention-and-therapy
#19
Roberta Bernini, Maria Saveria Gilardini Montani, Nicolò Merendino, Annalisa Romani, Francesca Velotti
Hydroxytyrosol [2-(3,4-dihydroxyphenyl)ethanol, HTyr] is a phenolic compound found in olive leaves and fruits and extra-virgin olive oil, which has well-known strong antioxidant and radical-scavenging properties. Recently, it has received particular attention for its antiproliferative and apoptotic activities and its anti-inflammatory properties. During the past few years, more efforts have been focused on synthesizing HTyr-derived compounds with enhanced biological activities for their potential use in different chronic degenerative diseases...
December 10, 2015: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/26133313/interventions-for-post-stroke-fatigue
#20
REVIEW
Simiao Wu, Mansur A Kutlubaev, Ho-Yan Y Chun, Eileen Cowey, Alex Pollock, Malcolm R Macleod, Martin Dennis, Elizabeth Keane, Michael Sharpe, Gillian E Mead
BACKGROUND: Post-stroke fatigue (PSF) is a common and distressing problem after stroke. The best ways to prevent or treat PSF are uncertain. Several different interventions can be argued to have a rational basis. OBJECTIVES: To determine whether, among people with stroke, any intervention reduces the proportion of people with fatigue, fatigue severity, or both; and to determine the effect of intervention on health-related quality of life, disability, dependency and death, and whether such intervention is cost effective...
July 2, 2015: Cochrane Database of Systematic Reviews
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