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https://www.readbyqxmd.com/read/28526929/analytical-management-of-patients-undergoing-oral-anticoagulant-therapy-could-have-a-strong-impact-on-clinical-outcomes-a-follow-up-study
#1
Vincenzo De Iuliis, Sebastiano Ursi, Gianfranco Vitullo, Irma Griffo, Antonio Marino, Marika Caruso, Francesco Cipollone, Sabrina Capodifoglio, Veronica Breda, Elena Toniato, Alfonso Pennelli, Pio Conti, Stefano Martinotti
INTRODUCTION: Oral anticoagulant therapy, such as vitamin K antagonists (VKAs), is prominent for the prevention of cerebral ischemic stroke or systemic embolism and all-cause mortality in patients with atrial fibrillation, venous thromboembolism, and mechanical or biological valve. VKA treatment requires monitoring of the international normalized ratio (INR) in order to maintain it in a therapeutic range, avoiding side effects, the main and most significant of which is bleeding. The aim of the present study was to evaluate the event rates of several clinical composite outcomes, such as bleeding, thromboembolic events, and all-cause death...
May 19, 2017: Cardiology and Therapy
https://www.readbyqxmd.com/read/28523318/hemobilia-through-aneurysm-of-the-right-hepatic-artery-22-months-after-laparoscopic-cholecystectomy-case-presentation
#2
Octavian Marius CreŢu, Radu Gheorghe Dan, Iulian Alexandru Ciprian Blidişel, LaurenŢiu Vasile Sima, Mihnea Munteanu, Ion Păun
Hemobilia is a rare cause of upper digestive bleeding, and it should be suspected when there are traumas of the liver area or surgical or exploratory interventions of the liver-bile-pancreas area in the patient's history. Iatrogenic bleeding occurs, most often, after transcutaneous bile punctures, laparoscopic cholecystectomies, cateterisms of the biliary ways. After such interventions, hemobilia may appear earlier, but also up to a few months later. We present a case of massive hemobilia occurring 22 months after a laparoscopic cholecystectomy...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28511430/study-on-the-relation-between-colorectal-cancer-and-gall-bladder-disease
#3
Siddharth Gosavi, R Rama Mishra, Vsm Praveen Kumar
INTRODUCTION: Colorectal cancer is cancer of the large intestine, the lower part of digestive system which includes the sigmoid colon and rectum. AIM: To study the relation of incidence of colorectal cancer with previous gall bladder disease or post-cholecystectomy status, a relation between gall bladder disease and smoking in particular and the most common region of colon involved in colorectal cancer in gall bladder disease and non-gall bladder disease patients...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28489846/-gastrointestinal-bleeding-and-acute-hepatic-failure-by-leptospirosis-an-entity-that-should-not-be-forgotten
#4
Carlos Alventosa Mateu, Lydia Plana Campos, Laura Larrey Ruíz, Raquel Acedo Mayordomo, Laura Sanchís Artero, Laura Peño Muñoz, Paola Concepción Núñez Martínez, Génesis Aurora Castillo López, Mercedes Latorre Sánchez, Juan José Urquijo Ponce, Moisés Diago Madrid, Javier Sempere García-Argüelles
Leptospirosis disease is caused by the spirochete Leptospira. It is a worldwide distribution zoonosis, with predominance in the tropics. In Spain, it is not frequent but some cases have been noticed especially in humid areas surrounded by rivers, lakes or ponds, such as Catalonia, Andalucia or the Valencian Community. It is transmitted by a variety of animals such as cows or rats, that are infected either by direct contact with these animals or their urine, or indirectly by consuming or being in contact with water contaminated by their urine...
January 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28463675/surgical-treatment-of-splenic-artery-pseudoaneurysm-with-digestive-tract-communication-presentation-of-two-cases
#5
Mihai Adrian Eftimie, Oana Maria Stanciulea, Leonard David, Vasile Lungu, Simona Dima, Iulian Mosteanu, Luiza Tirca, Irinel Popescu
Splenopancreatectomy performed for pancreatic pseudo-cyst with splenic artery pseudo-aneurysm and communication with the digestive tract (stomach or colon) is a very rare indication and a small number of these procedures are described in literature. Managing peri-pancreatic pseudo-aneurysm is complex and can be challenging. Surgical treatment is of curative intent and can involve multiple visceral resections. Surgery can be performed in an emergency setting, if the patient presents cataclysmic bleeding, or in a planned manner if the pseudo-aneurysm is discovered incidentally or if the patient manages to overcome the initial bleeding...
March 2017: Chirurgia
https://www.readbyqxmd.com/read/28413675/primary-mesenteric-adenocarcinoma-covered-by-abscess-of-the-mesocolon-and-intestinal-obstruction-a-case-report
#6
Yun Luo, Memgchuan Ou, Yushun Zhang, Zhiming Fu, Chongshu Wang
Primary mesenteric adenocarcinoma (PMA) is a rare malignant disease. A case of PMA that was covered by an abscess of the mesocolon and intestinal obstruction is reported in the present study. As the onset site of PMA is often obscured or hidden, there may be no clinical symptoms in the early stage. At the advanced stage, the tumor size is large enough to induce intestinal obstruction, perforation, bleeding, volvulus and other clinical symptoms in the majority of patients. Computed tomography scans, ultrasound and other auxiliary examinations are not sufficiently accurate for diagnosing PMA with non-specific characteristics in the majority of cases, causing certain difficulties in the pre-operative diagnosis of PMA, which easily lead to misdiagnosis...
April 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28405330/middle-term-mortality-and-re-bleeding-after-initial-diverticular-bleeding-a-nationwide-study-of-365-mostly-elderly-french-patients
#7
Diane Lorenzo, Claire Gallois, Pierre Lahmek, Bruno Lesgourgues, Christine Champion, Claire Charpignon, Roger Faroux, Bruno Bour, André-Jean Remy, Chantal Naouri, Magali Picon, Eric Poncin, Gilles Macaigne, Jacques-Arnaud Seyrig, David Bernardini, Guy Bellaïche, Denis Grasset, Jean Henrion, Frédéric Heluwaert, René Piperaud, Gilbert Bordes, Francois Bourhis, Jean-Pierre Arpurt, Alexandre Pariente, Stéphane Nahon
BACKGROUND AND AIMS: The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS: In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several French hospitals. We studied the follow-up of patients with DB retrospectively. The following data were collected: age, mortality rates and re-bleeding rates, drug intake, surgery and comorbidities...
February 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28405321/the-expansion-of-endoscopic-submucosal-dissection-in-france-a-prospective-nationwide-survey
#8
Maximilien Barret, Vincent Lepilliez, Dimitri Coumaros, Stanislas Chaussade, Sarah Leblanc, Thierry Ponchon, Fabien Fumex, Edouard Chabrun, Paul Bauret, Christophe Cellier, Emmanuel Coron, Philippe Bichard, Philippe Bulois, Antoine Charachon, Gabriel Rahmi, Serge Bellon, Marc Lerhun, Jean-Pierre Arpurt, Stéphane Koch, Bertrand Napoleon, Eric Vaillant, Anouk Esch, Said Farhat, Francoise Robin, Nadira Kaddour, Frédéric Prat
INTRODUCTION: Early reports of endoscopic submucosal dissection (ESD) in Europe suggested high complication rates and disappointing outcomes compared to publications from Japan. Since 2008, we have been conducting a nationwide survey to monitor the outcomes and complications of ESD over time. MATERIAL AND METHODS: All consecutive ESD cases from 14 centers in France were prospectively included in the database. Demographic, procedural, outcome and follow-up data were recorded...
February 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28380114/morphological-changes-in-the-digestive-system-of-322-necropsies-of-patients-with-acquired-immune-deficiency-syndrome-comparison-of-findings-pre-and-post-haart-highly-active-antiretroviral-therapy
#9
Lucinda Calheiros Guimarães, Ana Cristina Araújo Lemos da Silva, Adilha Misson Rua Micheletti, Everton Nunes Melo Moura, Mario Léon Silva-Vergara, Sebastião Tostes, Sheila Jorge Adad
Involvement of the digestive system in AIDS pathologies or injuries is frequent. Aiming at comparing the frequency, the importance that these lesions have for death and the survival time in patients using or not using HAART, we studied 322 necropsies classified as follows: Group A - without antiretroviral drugs (185 cases); B - one or two antiretroviral drugs or HAART for less than six months (83 cases); C - HAART for six months or longer (54 cases). In the overall analysis of the digestive system, changes were present in 73...
April 3, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28279616/-when-and-how-should-small-bowel-capsule-endoscopy-be-used-in-children
#10
J Viala, L Michaud, M Bellaiche, A Lachaux
Small-bowel capsule endoscopy (CE) has recently been used in children. During the past few years, an intense research activity has defined the advantages and limitations of CE. Its uses have been established in several small-bowel pathologies such as obvious or obscure digestive bleeding, Crohn disease, and hereditary polyposis. Although the absence of biopsy reduces the specificity of CE findings, small-bowel exploration using CE achieves better accuracy in detecting lesions than most radiological examinations...
March 6, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28226349/-prevention-and-treatment-of-complications-related-to-the-digestive-tract-reconstruction-in-laparoscopic-gastric-cancer-surgery
#11
Junsheng Peng, Shi Chen
With the development of laparoscopic techniques and equipments, laparoscopic-assisted, even total laparoscopic radical surgery for gastric cancer can be performed successfully. However, the incidence of postoperative complications is higher in the laparoscopy group as compared to the open-surgery group, which is still the barrier for the total laparoscopic radical gastrectomy. Similar to open surgery, the major complications of digestive tract reconstruction after laparoscopic radical gastrectomy are anastomotic leakage, anastomotic bleeding, anastomotic stricture and stenosis of input or output loop...
February 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28223734/early-thrombomodulin-%C3%AE-administration-outcome-for-acute-disseminated-intravascular-coagulopathy-in-gastrointestinal-surgery
#12
Hirotaka Konishi, Kazuma Okamoto, Katsutoshi Shoda, Tomohiro Arita, Toshiyuki Kosuga, Ryo Morimura, Shuhei Komatsu, Yasutoshi Murayama, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi, Daisuke Ichikawa, Hitoshi Fujiwara, Eigo Otsuji
AIM: To investigate the efficacy of thrombomodulin (TM)-α for treatment of disseminated intravascular coagulopathy (DIC) in the field of gastrointestinal surgery. METHODS: Thirty-six peri-operative DIC patients in the field of gastrointestinal surgery who were treated with TM-α were retrospectively investigated. The relationships between patient demographics and the efficacy of TM-α were examined. Analysis of survival at 28 d was also performed on some parameters by means of the Kaplan-Meier method...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28219552/unusual-gastrointestinal-bleeding-after-sutureless-aortic-valve-replacement-a-word-of-caution
#13
Jules Iquille, Joseph Nader, Eric Colpart, Thierry Caus
We report the clinical case of a male patient who presented, after an aortic valve replacement with a rapid deployment bioprosthesis, a Heyde-like syndrome, secondary to a moderate aortic paravalvular leakage. All the digestive and hematologic investigations confirmed the diagnosis. A redo surgery to fill the paravalvular gap was accomplished and the postoperative course was uneventful, with a normalization of the biological parameters. To our knowledge, this is the first described case of such a complication with the new generation of sutureless bioprosthesis...
March 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28211282/signet-ring-cell-carcinoma-of-the-jejunum-an-uncommon-finding-within-the-reach-of-capsule-endoscopy
#14
José Francisco Juanmartiñena, Marta Montes, Ignacio Fernández-Urién
An 80 year-old female presented with ductal breast carcinoma (stage II) three years ago, complained of asthenia and iron-deficiency anemia. No diagnosis was obtained after conventional endoscopy and iron supplements were indicated. Ten months later visible digestive hemorrhage was presented. Upper and lower endoscopy was repeated but non-diagnosis was obtained. Thus, video capsule endoscopy was indicated identifying a stenotic lesion arising in the mucosa of distal jejunum. Histopathological examination revealed a poorly mucinous differentiated signet-ring cell adenocarcinoma with an intense peri-tumoral lymphoid (Crohn´s-like lymphoid reaction) and lympho-vascular infiltration with no nodal metastases (pT3N0;7ª edition TNM classification)...
February 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28191810/gist-institutional-experience-at-srms-ims-india
#15
Shubhanshu Gupta, Keshri Amit, Ashish Gupta, Tanu Argawal
Gastro-Intestinal Stromal Tumors (GIST) is a malignant, non-epithelial, mesenchymal tumor of the digestive tract that is not uncommon in clinical practice nowadays; diagnosis being based upon immuno-histo-chemical analysis of the resected or biopsied (FNAC) specimen. Abdominal lump with or without intra-luminal bleed is a common mode of presentation. Early diagnosis and appropriate management with surgery and/or Imatinib therapy improves recurrence free survival and may impact overall survival. We present here our institutional experience of four patients, admitted in Onco-Surgery Dept...
September 2016: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28105625/-efficacy-of-over-the-scope-clip-for-gastrointestinal-fistula
#16
Gefei Wang, Zhiming Wang, Xiuwen Wu, Yanqing Diao, Yunzhao Zhao, Jianan Ren, Jieshou Li
OBJECTIVE: To explore the efficacy of over-the-scope clip (OTSC) in the treatment of gastrointestinal fistula. METHODS: Clinical data of 12 gastrointestinal fistula patients, including 3 internal fistula and 9 external fistula treated with OTSC in our institute from March 2015 to May 2016 were retrospectively analyzed. OTSC was performed when pus was drained thoroughly and intra-abdominal infection around gastrointestinal fistula was controlled, and each patient received one clip to close fistula...
January 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28062878/-an-unusual-finding-of-two-coins-together-in-the-esophagus-of-pediatric-patients-report-of-two-cases
#17
Alexis Ormeño Julca
The ingestion of foreign bodies (EB) is a frequent complaint in the Pediatric Emergency Services. Studies report that in children occurs 80% of the EC, most frequently between 6 months and 3 years old and the second held because of urgent endoscopy in pediatrics. In 80-90% of cases the CE spontaneously passes through the upper gastrointestinal tract, however occasionally staying in the esophagus and should be removed to avoid dangerous complications such as obstruction or perforation of the upper digestive tract bleeding, ulcers, or fistulas...
October 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28062865/-poor-outcome-factors-associated-to-patients-with-lower-digestive-bleeding-in-a-public-hospital
#18
Jorge Luis Rojas-Domínguez, Alvaro Carvallo-Michelena, Alejandro Piscoya, Edson Guzmán
BACKGROUND: Lower gastrointestinal bleeding (LGIB) is an event that has shown an increase in complications and mortality rates in the last decades. Although some factors associated with poor outcome have been identified, there are several yet to be evaluated. OBJECTIVE: To identify risk factors for poor outcome in patients with LGIB in the Hospital Edgardo Rebagliati Martins of Lima, Peru. MATERIAL AND METHODS: A prospective analytic observational cohort study was made, and a census was conducted with all patients with acute LGIB between January 2010 and December 2013...
October 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28060108/diagnostic-utility-of-complement-immunohistochemical-studies-in-post-stem-cell-transplant-intestinal-thrombotic-microangiopathy-case-report
#19
Jenna E Rossoff, Jennifer Schneiderman, Sonali Chaudhury, Nicoleta C Arva
Thrombotic complications are a significant source of morbidity and mortality following hematopoietic stem cell transplants. Among them, transplant-associated thrombotic microangiopathy (TA-TMA) is a well-recognized syndrome that can affect various organ systems. Its etiology is related to endothelial injury accompanied by complement activation. As many of the signs and symptoms of the disease are also encountered in other complications following hematopoietic stem cell transplant, it can often be difficult to establish the diagnosis based on clinical data alone...
May 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28057321/-digestive-bleeding-due-to-jejunal-diverticula-a-case-report-and-literature-review
#20
Jorge Cuauhtémoc Blake-Siemsen, Marisol Kortright-Farías, Dante Rafael Casale-Menier, Jesús Gámez-Araujo
BACKGROUND: Bleeding from the small bowel is a rare pathology that represents 5-10% of gastrointestinal bleeding; 0.06% to 5% of cases are due to the presence of diverticula of the small intestine. The majority of diverticula are asymptomatic and present symptoms when there is a complication. CLINICAL CASE: We present the case of a 53-year-old male with a history of chronic renal failure and hypertension. While he was hospitalized due to cerebrovascular disease he recurrently presented lower gastrointestinal bleeding that required blood transfusion on several occasions...
January 2, 2017: Cirugia y Cirujanos
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